The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) Holliday junctions to functional replication forks

Biochemistry

Volumn 50, Issue 32, 2011, Pages 6774-6788

  MacHwe, Amrita ^a   Karale, Rajashree ^a   Xu, Xioahua ^b   Liu, Yilun ^b   Orren, David K ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; BINDING PROTEINS; BLOOM SYNDROME; BRANCH MIGRATION; CONVERSION REACTIONS; DAUGHTER STRANDS; DNA POLYMERASE; DNA SYNTHESISS; GENOMIC INSTABILITY; GENOMIC STABILITY; HOLLIDAY JUNCTION SUBSTRATES; HOLLIDAY JUNCTIONS; RECOMBINATION INTERMEDIATES; RECQ HELICASES; REPLICATION FORK;

BLOOMS (METAL); DNA; GENES;

BIOSYNTHESIS;

ADENOSINE TRIPHOSPHATE; BLOOM SYNDROME HELICASE; DNA POLYMERASE; MAGNESIUM CHLORIDE; WERNER SYNDROME PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA REPLICATION; DNA REPLICATION ORIGIN; DNA STRAND; GENE CONVERSION; HOLLIDAY JUNCTION; HUMAN; HYDROLYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

DNA; DNA REPLICATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EXODEOXYRIBONUCLEASES; HUMANS; RECOMBINANT PROTEINS; RECQ HELICASES; SUBSTRATE SPECIFICITY;

EID: 80051512519     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2001054     Document Type: Article

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