Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein

Journal of Biological Chemistry

Volumn 279, Issue 33, 2004, Pages 34603-34613

  Choudhary, Saba ^a   Sommers, Joshua A ^a   Brosh Jr , Robert M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CONCENTRATION (PROCESS); ENZYME KINETICS; GENES; MAGNESIUM PRINTING PLATES; MONOMERS; POSITIVE IONS; PROTEINS; SUBSTRATES;

COFACTORS; FLUOROMETRIC ASSAY; MOLECULAR SWITCHES; WERNER SYNDROME;

DNA;

ADENOSINE TRIPHOSPHATE MAGNESIUM; COPPER ION; EXONUCLEASE; FERROUS ION; HELICASE; MAGNESIUM ION; NICKEL; WERNER SYNDROME PROTEIN; ZINC ION; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; COPPER; DNA; ION; IRON; MAGNESIUM; MANGANESE; METAL; RECQ HELICASE; RECQL PROTEIN, HUMAN; SINGLE STRANDED DNA; WRN PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL ANALYSIS; CONTROLLED STUDY; DNA DENATURATION; ENZYME ACTIVITY; ENZYME KINETICS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUOROMETRY; HUMAN; INSECT CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; WERNER SYNDROME; ANIMAL; CELL LINE; CHEMISTRY; DOSE RESPONSE; INSECT; KINETICS; METABOLISM; PHYSIOLOGY; TIME;

ANIMALIA; INSECTA;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CATALYSIS; CELL LINE; COPPER; DNA; DNA HELICASES; DNA, SINGLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXONUCLEASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; INSECTS; IONS; IRON; KINETICS; MAGNESIUM; MANGANESE; METALS; NICKEL; RECQ HELICASES; TIME FACTORS;

EID: 4544295237     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401901200     Document Type: Article

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