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Volumn 8, Issue 17, 2009, Pages 2686-2691

Whither the replisome: Emerging perspectives on the dynamic nature of the DNA replication machinery

Author keywords

DNA helicase; DNA polymerase; DNA repair; DNA replication; Replisome; Translesion polymerase

Indexed keywords

DNA POLYMERASE; DNAB HELICASE; HELICASE; REPLISOME;

EID: 69749124647     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.17.9390     Document Type: Review
Times cited : (58)

References (56)
  • 2
    • 22244478079 scopus 로고    scopus 로고
    • Cellular DNA replicases: Components and dynamics at the replication fork
    • DOI 10.1146/annurev.biochem.73.011303.073859
    • Johnson A, O'Donnell M. Cellular DNA replicases: components and dynamics at the replication fork. Annu Rev Biochem 2005; 74:283-315. (Pubitemid 40995509)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 283-315
    • Johnson, A.1    O'Donnell, M.2
  • 4
    • 0141677891 scopus 로고    scopus 로고
    • Chromosomal replicases as asymmetric dimers: Studies of subunit arrangement and functional consequences
    • McHenry CS. Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequences. Mol Microbiol 2003; 49:1157-1165
    • (2003) Mol Microbiol , vol.49 , pp. 1157-1165
    • McHenry, C.S.1
  • 5
    • 58249114971 scopus 로고    scopus 로고
    • Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
    • Hamdan SM, Loparo JJ, Takahashi M, Richardson CC, van Oijen AM. Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis. Nature 2009; 457:336-339
    • (2009) Nature , vol.457 , pp. 336-339
    • Hamdan, S.M.1    Loparo, J.J.2    Takahashi, M.3    Richardson, C.C.4    Van Oijen, A.M.5
  • 6
    • 58149357530 scopus 로고    scopus 로고
    • Replisome dynamics and use of DNA trombone loops to bypass replication blocks
    • Yao NY, O'Donnell M. Replisome dynamics and use of DNA trombone loops to bypass replication blocks. Mol Biosyst 2008; 4:1075-1084
    • (2008) Mol Biosyst , vol.4 , pp. 1075-1084
    • Yao, N.Y.1    O'Donnell, M.2
  • 7
    • 21244442328 scopus 로고    scopus 로고
    • Discontinuous or semi-discontinuous DNA replication in Escherichia coli?
    • Wang TC. Discontinuous or semi-discontinuous DNA replication in Escherichia coli? Bioessays 2005; 27:633-636
    • (2005) Bioessays , vol.27 , pp. 633-636
    • Wang, T.C.1
  • 8
    • 0030070356 scopus 로고    scopus 로고
    • Coupling of a replicative polymerase and helicase: A tau-DnaB interaction mediates rapid replication fork movement
    • DOI 10.1016/S0092-8674(00)81039-9
    • Kim S, Dallmann HG, McHenry CS, Marians KJ. Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement. Cell 1996; 84:643-650 (Pubitemid 26071744)
    • (1996) Cell , vol.84 , Issue.4 , pp. 643-650
    • Kim, S.1    Dallmann, H.G.2    McHenry, C.S.3    Marians, K.J.4
  • 9
    • 14544291633 scopus 로고    scopus 로고
    • DNA polymerase clamp loaders and DNA recognition
    • DOI 10.1016/j.febslet.2004.11.038
    • Bowman GD, Goedken ER, Kazmirski SL, O'Donnell M, Kuriyan J. DNA polymerase clamp loaders and DNA recognition. FEBS Lett 2005; 579:863-867 (Pubitemid 40361855)
    • (2005) FEBS Letters , vol.579 , Issue.4 SPEC. ISS , pp. 863-867
    • Bowman, G.D.1    Goedken, E.R.2    Kazmirski, S.L.3    O'Donnell, M.4    Kuriyan, J.5
  • 10
    • 0019223518 scopus 로고
    • Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system
    • Sinha NK, Morris CF, Alberts BM. Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system. J Biol Chem 1980; 255:4290-4293
    • (1980) J Biol Chem , vol.255 , pp. 4290-4293
    • Sinha, N.K.1    Morris, C.F.2    Alberts, B.M.3
  • 11
    • 0034602402 scopus 로고    scopus 로고
    • Two distinct triggers for cycling of the lagging strand polymerase at the replication fork
    • Li X, Marians KJ. Two distinct triggers for cycling of the lagging strand polymerase at the replication fork. J Biol Chem 2000; 275:34757-34765 (Pubitemid 30819255)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.44 , pp. 34757-34765
    • Li, X.1    Marians, K.J.2
  • 12
    • 0028093437 scopus 로고
    • An explanation for lagging strand replication: Polymerase hopping among DNA sliding clamps
    • DOI 10.1016/S0092-8674(94)90662-9
    • Stukenberg PT, Turner J, O'Donnell M. An explanation for lagging strand replication: polymerase hopping among DNA sliding clamps. Cell 1994; 78:877-887 (Pubitemid 24294462)
    • (1994) Cell , vol.78 , Issue.5 , pp. 877-887
    • Todd Stukenberg, P.1    Turner, J.2    O'Donnell, M.3
  • 13
    • 57649139149 scopus 로고    scopus 로고
    • DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA
    • Langston LD, O'Donnell M. DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. J Biol Chem 2008; 283:29522-29531
    • (2008) J Biol Chem , vol.283 , pp. 29522-29531
    • Langston, L.D.1    O'Donnell, M.2
  • 14
    • 30744446944 scopus 로고    scopus 로고
    • The control mechanism for lagging strand polymerase recycling during bacteriophage T4 DNA replication
    • DOI 10.1016/j.molcel.2005.11.029, PII S1097276505018447
    • Yang J, Nelson SW, Benkovic SJ. The control mechanism for lagging strand polymerase recycling during bacteriophage T4 DNA replication. Mol Cell 2006; 21:153-164 (Pubitemid 43099932)
    • (2006) Molecular Cell , vol.21 , Issue.2 , pp. 153-164
    • Yang, J.1    Nelson, S.W.2    Benkovic, S.J.3
  • 16
    • 9144264274 scopus 로고    scopus 로고
    • Defining the position of the switches between replicative and bypass DNA polymerases
    • DOI 10.1038/sj.emboj.7600438
    • Fujii S, Fuchs RP. Defining the position of the switches between replicative and bypass DNA polymerases. EMBO J 2004; 23:4342-4352 (Pubitemid 39546171)
    • (2004) EMBO Journal , vol.23 , Issue.21 , pp. 4342-4352
    • Fujii, S.1    Fuchs, R.P.2
  • 17
    • 0035997344 scopus 로고    scopus 로고
    • Error-prone repair DNA polymerases in prokaryotes and eukaryotes
    • Goodman MF. Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Annu Rev Biochem 2002; 71:17-50.
    • (2002) Annu Rev Biochem , vol.71 , pp. 17-50
    • Goodman, M.F.1
  • 19
    • 33745200274 scopus 로고    scopus 로고
    • Monitoring DNA replication following UV-induced damage in Escherichia coli
    • Courcelle CT, Courcelle J. Monitoring DNA replication following UV-induced damage in Escherichia coli. Methods Enzymol 2006; 409:425-441
    • (2006) Methods Enzymol , vol.409 , pp. 425-441
    • Courcelle, C.T.1    Courcelle, J.2
  • 20
    • 0037799191 scopus 로고    scopus 로고
    • Uncoupling of leading- And lagging-strand DNA replication during lesion bypass in vivo
    • DOI 10.1126/science.1083964
    • Pages V, Fuchs RP. Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo. Science 2003; 300:1300-1303 (Pubitemid 36618243)
    • (2003) Science , vol.300 , Issue.5623 , pp. 1300-1303
    • Pages, V.1    Fuchs, R.P.2
  • 21
    • 0030469755 scopus 로고    scopus 로고
    • Damage inducible mutagenesis: Recent insights into the activities of the Umu family of mutagenesis proteins
    • Woodgate R, Levine AS. Damage inducible mutagenesis: recent insights into the activities of the Umu family of mutagenesis proteins. Cancer Surv 1996; 28:117-140 (Pubitemid 27023755)
    • (1996) Cancer Surveys , vol.28 , pp. 117-140
    • Woodgate, R.1    Levine, A.S.2
  • 22
    • 65549153598 scopus 로고    scopus 로고
    • Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase
    • Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell M. Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Proc Natl Acad Sci USA 2009; 106:6031-6038
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6031-6038
    • Indiani, C.1    Langston, L.D.2    Yurieva, O.3    Goodman, M.F.4    O'Donnell, M.5
  • 23
    • 45549085521 scopus 로고    scopus 로고
    • A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp
    • Furukohri A, Goodman MF, Maki H. A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp. J Biol Chem 2008; 283:11260-11269
    • (2008) J Biol Chem , vol.283 , pp. 11260-11269
    • Furukohri, A.1    Goodman, M.F.2    Maki, H.3
  • 24
    • 24944543952 scopus 로고    scopus 로고
    • A sliding-clamp toolbelt binds high- And low-fidelity DNA polymerases simultaneously
    • DOI 10.1016/j.molcel.2005.08.011, PII S1097276505015534
    • Indiani C, McInerney P, Georgescu R, Goodman MF, O'Donnell M. A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously. Mol Cell 2005; 19:805-815 (Pubitemid 41316674)
    • (2005) Molecular Cell , vol.19 , Issue.6 , pp. 805-815
    • Indiani, C.1    McInerney, P.2    Georgescu, R.3    Goodman, M.F.4    O'Donnell, M.5
  • 27
    • 0035023305 scopus 로고    scopus 로고
    • Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli
    • Courcelle J, Khodursky A, Peter B, Brown PO, Hanawalt PC. Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics 2001; 158:41-64. (Pubitemid 32428629)
    • (2001) Genetics , vol.158 , Issue.1 , pp. 41-64
    • Tornier, C.1    Bessone, S.2    Varlet, I.3    Rudolph, C.4    Darmon, M.5    Fleck, O.6
  • 28
    • 0025815515 scopus 로고
    • Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage
    • Woodgate R, Ennis DG. Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage. Mol Gen Genet 1991; 229:10-16
    • (1991) Mol Gen Genet , vol.229 , pp. 10-16
    • Woodgate, R.1    Ennis, D.G.2
  • 29
    • 53849083443 scopus 로고    scopus 로고
    • Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal
    • Uchida K, Furukohri A, Shinozaki Y, Mori T, Ogawara D, Kanaya S, et al. Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal. Mol Microbiol 2008; 70:608-622
    • (2008) Mol Microbiol , vol.70 , pp. 608-622
    • Uchida, K.1    Furukohri, A.2    Shinozaki, Y.3    Mori, T.4    Ogawara, D.5    Kanaya, S.6
  • 30
    • 37349132340 scopus 로고    scopus 로고
    • UmuD and RecA Directly Modulate the Mutagenic Potential of the Y Family DNA Polymerase DinB
    • DOI 10.1016/j.molcel.2007.10.025, PII S1097276507007320
    • Godoy VG, Jarosz DF, Simon SM, Abyzov A, Ilyin V, Walker GC. UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. Mol Cell 2007; 28:1058-1070 (Pubitemid 350297024)
    • (2007) Molecular Cell , vol.28 , Issue.6 , pp. 1058-1070
    • Godoy, V.G.1    Jarosz, D.F.2    Simon, S.M.3    Abyzov, A.4    Ilyin, V.5    Walker, G.C.6
  • 31
    • 17644443277 scopus 로고    scopus 로고
    • A motor that makes its own track: Helicase unwinding of DNA
    • Betterton MD, Julicher F. A motor that makes its own track: helicase unwinding of DNA. Phys Rev Lett 2003; 91:258103.
    • (2003) Phys Rev Lett , vol.91 , pp. 258103
    • Betterton, M.D.1    Julicher, F.2
  • 32
    • 0029893874 scopus 로고    scopus 로고
    • Mechanisms of helicase-catalyzed DNA unwinding
    • Lohman TM, Bjornson KP. Mechanisms of helicase-catalyzed DNA unwinding. Annu Rev Biochem 1996; 65:169-214.
    • (1996) Annu Rev Biochem , vol.65 , pp. 169-214
    • Lohman, T.M.1    Bjornson, K.P.2
  • 33
    • 0035150184 scopus 로고    scopus 로고
    • Unwinding the 'Gordian knot' of helicase action
    • Soultanas P, Wigley DB. Unwinding the 'Gordian knot' of helicase action. Trends Biochem Sci 2001; 26:47-54.
    • (2001) Trends Biochem Sci , vol.26 , pp. 47-54
    • Soultanas, P.1    Wigley, D.B.2
  • 34
    • 0035951425 scopus 로고    scopus 로고
    • A general model for nucleic acid helicases and their "coupling" within macromolecular machines
    • von Hippel PH, Delagoutte E. A general model for nucleic acid helicases and their "coupling" within macromolecular machines. Cell 2001; 104:177-190
    • (2001) Cell , vol.104 , pp. 177-190
    • Von Hippel, P.H.1    Delagoutte, E.2
  • 35
    • 0345492316 scopus 로고    scopus 로고
    • Macromolecular complexes that unwind nucleic acids
    • DOI 10.1002/bies.10369
    • von Hippel PH, Delagoutte E. Macromolecular complexes that unwind nucleic acids. Bioessays 2003; 25:1168-1177 (Pubitemid 37499317)
    • (2003) BioEssays , vol.25 , Issue.12 , pp. 1168-1177
    • Von Hippel, P.H.1    Delagoutte, E.2
  • 36
    • 33749121811 scopus 로고    scopus 로고
    • Mechanisms of a ring shaped helicase
    • Donmez I, Patel SS. Mechanisms of a ring shaped helicase. Nucleic Acids Res 2006; 34:4216-4224
    • (2006) Nucleic Acids Res , vol.34 , pp. 4216-4224
    • Donmez, I.1    Patel, S.S.2
  • 37
    • 34250766751 scopus 로고    scopus 로고
    • Single-Molecule Studies Reveal Dynamics of DNA Unwinding by the Ring-Shaped T7 Helicase
    • DOI 10.1016/j.cell.2007.04.038, PII S0092867407005843
    • Johnson DS, Bai L, Smith BY, Patel SS, Wang MD. Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase. Cell 2007; 129:1299-1309 (Pubitemid 46962089)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1299-1309
    • Johnson, D.S.1    Bai, L.2    Smith, B.Y.3    Patel, S.S.4    Wang, M.D.5
  • 38
    • 0035836479 scopus 로고    scopus 로고
    • Molecular mechanisms of the functional coupling of the helicase (gp41) and polymerase (gp43) of bacteriophage T4 within the DNA replication fork
    • DOI 10.1021/bi001306l
    • Delagoutte E, von Hippel PH. Molecular mechanisms of the functional coupling of the helicase (gp41) and polymerase (gp43) of bacteriophage T4 within the DNA replication fork. Biochemistry 2001; 40:4459-4477 (Pubitemid 32319592)
    • (2001) Biochemistry , vol.40 , Issue.14 , pp. 4459-4477
    • Delagoutte, E.1    Von Hippel, P.H.2
  • 39
    • 0035830834 scopus 로고    scopus 로고
    • Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB
    • Gao D, McHenry CS. tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB. J Biol Chem 2001; 276:4441-4446
    • (2001) J Biol Chem , vol.276 , pp. 4441-4446
    • Gao, D.1    McHenry, C.S.2
  • 40
    • 34547730912 scopus 로고    scopus 로고
    • Characterization of a Triple DNA Polymerase Replisome
    • DOI 10.1016/j.molcel.2007.06.019, PII S1097276507004108
    • McInerney P, Johnson A, Katz F, O'Donnell M. Characterization of a triple DNA polymerase replisome. Mol Cell 2007; 27:527-538 (Pubitemid 47238627)
    • (2007) Molecular Cell , vol.27 , Issue.4 , pp. 527-538
    • McInerney, P.1    Johnson, A.2    Katz, F.3    O'Donnell, M.4
  • 41
    • 33747332833 scopus 로고    scopus 로고
    • The replication intermediates in Escherichia coli are not the product of DNA processing or uracil excision
    • Amado L, Kuzminov A. The replication intermediates in Escherichia coli are not the product of DNA processing or uracil excision. J Biol Chem 2006; 281:22635-22646
    • (2006) J Biol Chem , vol.281 , pp. 22635-22646
    • Amado, L.1    Kuzminov, A.2
  • 42
    • 29544437558 scopus 로고    scopus 로고
    • Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
    • DOI 10.1016/j.molcel.2005.11.015, PII S1097276505018022
    • Lopes M, Foiani M, Sogo JM. Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol Cell 2006; 21:15-27. (Pubitemid 43017845)
    • (2006) Molecular Cell , vol.21 , Issue.1 , pp. 15-27
    • Lopes, M.1    Foiani, M.2    Sogo, J.M.3
  • 43
    • 31844456472 scopus 로고    scopus 로고
    • Replication fork reactivation downstream of a blocked nascent leading strand
    • Heller RC, Marians KJ. Replication fork reactivation downstream of a blocked nascent leading strand. Nature 2006; 439:557-562
    • (2006) Nature , vol.439 , pp. 557-562
    • Heller, R.C.1    Marians, K.J.2
  • 44
    • 33745932747 scopus 로고    scopus 로고
    • DNA Replication: Keep Moving and Don't Mind the Gap
    • DOI 10.1016/j.molcel.2006.05.034, PII S1097276506003765
    • Langston LD, O'Donnell M. DNA replication: keep moving and don't mind the gap. Mol Cell 2006; 23:155-160 (Pubitemid 44062369)
    • (2006) Molecular Cell , vol.23 , Issue.2 , pp. 155-160
    • Langston, L.D.1    O'Donnell, M.2
  • 45
    • 57649129186 scopus 로고    scopus 로고
    • The replisome uses mRNA as a primer after colliding with RNA polymerase
    • Pomerantz RT, O'Donnell M. The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature 2008; 456:762-766
    • (2008) Nature , vol.456 , pp. 762-766
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 46
    • 33947432388 scopus 로고    scopus 로고
    • Replication fork stalling at natural impediments
    • Mirkin EV, Mirkin SM. Replication fork stalling at natural impediments. Microbiol Mol Biol Rev 2007; 71:13-35.
    • (2007) Microbiol Mol Biol Rev , vol.71 , pp. 13-35
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 47
    • 34249941504 scopus 로고    scopus 로고
    • Avoiding and resolving conflicts between DNA replication and transcription
    • DOI 10.1016/j.dnarep.2007.02.017, PII S1568786407000687, Replication Fork Repair Processes
    • Rudolph CJ, Dhillon P, Moore T, Lloyd RG. Avoiding and resolving conflicts between DNA replication and transcription. DNA Repair (Amst) 2007; 6:981-993 (Pubitemid 46880478)
    • (2007) DNA Repair , vol.6 , Issue.7 , pp. 981-993
    • Rudolph, C.J.1    Dhillon, P.2    Moore, T.3    Lloyd, R.G.4
  • 48
    • 0024276903 scopus 로고
    • When polymerases collide: Replication and the transcriptional organization of the E. coli chromosome
    • Brewer BJ. When polymerases collide: replication and the transcriptional organization of the E. coli chromosome. Cell 1988; 53:679-686
    • (1988) Cell , vol.53 , pp. 679-686
    • Brewer, B.J.1
  • 50
    • 0025328320 scopus 로고
    • Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin
    • DOI 10.1038/346534a0
    • Tsurimoto T, Melendy T, Stillman B. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 1990; 346:534-539 (Pubitemid 20238801)
    • (1990) Nature , vol.346 , Issue.6284 , pp. 534-539
    • Tsurimoto, T.1    Melendy, T.2    Stillman, B.3
  • 52
    • 47349114465 scopus 로고    scopus 로고
    • The Mcm2-7 Complex Has in Vitro Helicase Activity
    • DOI 10.1016/j.molcel.2008.05.020, PII S1097276508003985
    • Bochman ML, Schwacha A. The Mcm2-7 complex has in vitro helicase activity. Mol Cell 2008; 31:287-293 (Pubitemid 352001397)
    • (2008) Molecular Cell , vol.31 , Issue.2 , pp. 287-293
    • Bochman, M.L.1    Schwacha, A.2
  • 53
    • 33745925880 scopus 로고    scopus 로고
    • Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
    • Moyer SE, Lewis PW, Botchan MR. Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc Natl Acad Sci USA 2006; 103:10236-10241
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10236-10241
    • Moyer, S.E.1    Lewis, P.W.2    Botchan, M.R.3
  • 54
    • 54249092768 scopus 로고    scopus 로고
    • Dividing the workload at a eukaryotic replication fork
    • Kunkel TA, Burgers PM. Dividing the workload at a eukaryotic replication fork. Trends Cell Biol 2008; 18:521-527
    • (2008) Trends Cell Biol , vol.18 , pp. 521-527
    • Kunkel, T.A.1    Burgers, P.M.2
  • 55
    • 34447336941 scopus 로고    scopus 로고
    • Yeast DNA polymerase epsilon participates in leading-strand DNA replication
    • DOI 10.1126/science.1144067
    • Pursell ZF, Isoz I, Lundstrom EB, Johansson E, Kunkel TA. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science 2007; 317:127-130 (Pubitemid 47056472)
    • (2007) Science , vol.317 , Issue.5834 , pp. 127-130
    • Pursell, Z.F.1    Isoz, I.2    Lundstrom, E.-B.3    Johansson, E.4    Kunkel, T.A.5
  • 56
    • 0037292424 scopus 로고    scopus 로고
    • Mechanism of the E. coli tau processivity switch during lagging-strand synthesis
    • Leu FP, Georgescu R, O'Donnell M. Mechanism of the E. coli tau processivity switch during lagging-strand synthesis. Mol Cell 2003; 11:315-327
    • (2003) Mol Cell , vol.11 , pp. 315-327
    • Leu, F.P.1    Georgescu, R.2    O'Donnell, M.3


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