The extended TILAR approach: A novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes

BMC Systems Biology

Volumn 6, Issue , 2012, Pages

  Vlaic, Sebastian ^a   Schmidt Heck, Wolfgang ^a   Matz Soja, Madlen ^b   Marbach, Eugenia ^b   Linde, Jörg ^a   Meyer Baese, Anke ^c   Zellmer, Sebastian ^d   Guthke, Reinhard ^a   Gebhardt, Rolf ^b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c FLORIDA STATE UNIVERSITY   (United States)

^d FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Atf3 activating transcription factor 3; Dbp D site albumin promoter binding protein; Dynamic network inference; Gene regulation; Hepatocytes; Key regulator identification; Least angle regression; Linear modeling; Liver; Tgif1 TGFB induced factor homeobox 1; Transcription factor networks

Indexed keywords

MURINAE;

TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL CYCLE; CELL PROLIFERATION; CULTURE TECHNIQUE; CYTOLOGY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LIVER CELL; METABOLISM; METHODOLOGY; MOUSE; REPRODUCIBILITY; SYSTEMS BIOLOGY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HEPATOCYTES; MICE; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; SYSTEMS BIOLOGY; TRANSCRIPTION FACTORS;

MLCS; MLOWN;

EID: 84870053474     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-6-147     Document Type: Article

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