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Volumn 27, Issue 11, 2012, Pages 1361-1383

Genes promoting and disturbing testis development

Author keywords

AMH; CTNNB1; DAX1; DMRT1; FGF9; FOG2; FOXL2; GATA4; PDGFRa; SF1; SOX10; SOX3; SOX8; SOX9; SRY; WT1

Indexed keywords

ANIMAL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; MALE; METABOLISM; ORGANOGENESIS; PRENATAL DEVELOPMENT; REVIEW; SEX DIFFERENTIATION; TESTIS;

EID: 84869437982     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (44)

References (288)
  • 2
    • 0032990419 scopus 로고    scopus 로고
    • A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans
    • Achermann J.C., Ito M., Ito M., Hindmarsh P.C. and Jameson J.L. (1999). A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans. Nat. Genet. 22, 125-126.
    • (1999) Nat. Genet. , vol.22 , pp. 125-126
    • Achermann, J.C.1    Ito, M.2    Ito, M.3    Hindmarsh, P.C.4    Jameson, J.L.5
  • 4
    • 0036337282 scopus 로고    scopus 로고
    • Sexually dimorphic development of mouse primordial germ cells: Switching from oogenesis to spermatogenesis
    • Adams I.R. and McLaren A. (2002). Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. Development 129, 1155-1164.
    • (2002) Development , vol.129 , pp. 1155-1164
    • Adams, I.R.1    McLaren, A.2
  • 5
    • 1842406592 scopus 로고    scopus 로고
    • Hormonal and cellular regulation of Sertoli cell anti-Mullerian hormone production in the postnatal mouse
    • Al-Attar L., Noel K., Dutertre M., Belville C., Forest M., Burgoyne P., Josso N. and Rey R. (1997). Hormonal and cellular regulation of Sertoli cell anti-Mullerian hormone production in the postnatal mouse. J. Clin. Invest. 100, 1335-1343.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1335-1343
    • Al-Attar, L.1    Noel, K.2    Dutertre, M.3    Belville, C.4    Forest, M.5    Burgoyne, P.6    Josso, N.7    Rey, R.8
  • 6
    • 0035578297 scopus 로고    scopus 로고
    • Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor
    • Albrecht K.H. and Eicher E.M. (2001). Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor. Dev. Biol. 240, 92-107.
    • (2001) Dev. Biol. , vol.240 , pp. 92-107
    • Albrecht, K.H.1    Eicher, E.M.2
  • 7
  • 8
    • 0037377936 scopus 로고    scopus 로고
    • FOG-2 and GATA-4 are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression
    • Anttonen M., Ketola I., Parviainen H., Pusa A. and Heikinheimo M. (2003). FOG-2 and GATA-4 are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression. Biol. Reprod. 68, 1333-1340.
    • (2003) Biol. Reprod. , vol.68 , pp. 1333-1340
    • Anttonen, M.1    Ketola, I.2    Parviainen, H.3    Pusa, A.4    Heikinheimo, M.5
  • 9
    • 0032705186 scopus 로고    scopus 로고
    • Targeted mutagenesis of the endogenous mouse Mis gene promoter: In vivo de?nition of genetic pathways of vertebrate sexual development
    • Arango N.A., Lovell-Badge R. and Behringer R.R. (1999). Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo de?nition of genetic pathways of vertebrate sexual development. Cell 99, 409-419.
    • (1999) Cell , vol.99 , pp. 409-419
    • Arango, N.A.1    Lovell-Badge, R.2    Behringer, R.R.3
  • 10
    • 0027450889 scopus 로고
    • Mouse GATA-4: A retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart
    • Arceci R.J., King A.A., Simon M.C., Orkin S.H. and Wilson D.B. (1993). Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell. Biol. 13, 2235-2246.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2235-2246
    • Arceci, R.J.1    King, A.A.2    Simon, M.C.3    Orkin, S.H.4    Wilson, D.B.5
  • 11
    • 67449090378 scopus 로고    scopus 로고
    • Epithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development
    • Archambeault D.R., Tomaszewski J., Joseph A., Hinton B.T. and Yao H.H. (2009). Epithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development. Genesis 47, 40-48.
    • (2009) Genesis , vol.47 , pp. 40-48
    • Archambeault, D.R.1    Tomaszewski, J.2    Joseph, A.3    Hinton, B.T.4    Yao, H.H.5
  • 12
    • 0027054125 scopus 로고
    • The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo
    • Armstrong J., Pritchard-Jones K., Bickmore W., Hastie N. and Bard J. (1993). The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech. Dev. 40, 85-97.
    • (1993) Mech. Dev. , vol.40 , pp. 85-97
    • Armstrong, J.1    Pritchard-Jones, K.2    Bickmore, W.3    Hastie, N.4    Bard, J.5
  • 13
    • 0026470288 scopus 로고
    • Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome
    • Baird P., Groves N., Haber D., Housman D. and Cowell J. (1992). Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome. Oncogene 7, 2141-2149.
    • (1992) Oncogene , vol.7 , pp. 2141-2149
    • Baird, P.1    Groves, N.2    Haber, D.3    Housman, D.4    Cowell, J.5
  • 16
    • 76549106275 scopus 로고    scopus 로고
    • SOX E genes: SOX9 and SOX8 in mammalian testis development
    • Barrionuevo F. and Scherer G. (2010). SOX E genes: SOX9 and SOX8 in mammalian testis development. Int. J. Biochem. Cell. Biol. 42, 433-436.
    • (2010) Int. J. Biochem. Cell. Biol. , vol.42 , pp. 433-436
    • Barrionuevo, F.1    Scherer, G.2
  • 17
    • 33746027560 scopus 로고    scopus 로고
    • Sox9 is required for notochord maintenance in mice
    • Barrionuevo F., Taketo M.M., Scherer G. and Kispert A. (2006a). Sox9 is required for notochord maintenance in mice. Dev. Biol. 295, 128-140.
    • (2006) Dev. Biol. , vol.295 , pp. 128-140
    • Barrionuevo, F.1    Taketo, M.M.2    Scherer, G.3    Kispert, A.4
  • 19
    • 60849087698 scopus 로고    scopus 로고
    • Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8
    • Barrionuevo F., Georg I., Scherthan H., Lécureuil C., Guillou F., Wegner M. and Scherer G. (2009). Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev. Biol. 327, 301-312.
    • (2009) Dev. Biol. , vol.327 , pp. 301-312
    • Barrionuevo, F.1    Georg, I.2    Scherthan, H.3    Lécureuil, C.4    Guillou, F.5    Wegner, M.6    Scherer, G.7
  • 20
    • 58549121150 scopus 로고    scopus 로고
    • Blurring the edges in vertebrate sex determination
    • Barske L.A. and Capel B. (2008). Blurring the edges in vertebrate sex determination. Curr. Opin. Genet. Dev. 18, 499-505.
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 499-505
    • Barske, L.A.1    Capel, B.2
  • 22
    • 0025312139 scopus 로고
    • Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance
    • Behringer R., Cate R., Froelick G., Palmiter R. and Brinster R. (1990). Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance. Nature 345, 167-70.
    • (1990) Nature , vol.345 , pp. 167-170
    • Behringer, R.1    Cate, R.2    Froelick, G.3    Palmiter, R.4    Brinster, R.5
  • 25
    • 0042703900 scopus 로고    scopus 로고
    • Dimerization of SOX9 is required for chondrogenesis, but not for sex determination
    • Bernard P., Tang P., Liu S., Dewing P., Harley V.R. and Vilain E. (2003). Dimerization of SOX9 is required for chondrogenesis, but not for sex determination. Hum. Mol. Genet. 12, 1755-1765.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1755-1765
    • Bernard, P.1    Tang, P.2    Liu, S.3    Dewing, P.4    Harley, V.R.5    Vilain, E.6
  • 30
    • 55749084389 scopus 로고    scopus 로고
    • WNT4 and sex development
    • Biason-Lauber A. and Konrad D. (2008). WNT4 and sex development. Sex. Dev. 2, 210-218.
    • (2008) Sex. Dev. , vol.2 , pp. 210-218
    • Biason-Lauber, A.1    Konrad, D.2
  • 31
    • 4143139955 scopus 로고    scopus 로고
    • A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46, XX woman
    • Biason-Lauber A., Konrad D., Navratil F. and Schoenle E.J. (2004). A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46, XX woman. N. Engl. J. Med. 351, 792-798.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 792-798
    • Biason-Lauber, A.1    Konrad, D.2    Navratil, F.3    Schoenle, E.J.4
  • 32
    • 65149088653 scopus 로고    scopus 로고
    • Ovaries and female phenotype in a girl with 46, XY karyotype and mutations in the CBX2 gene
    • Biason-Lauber A., Konrad D., Meyer M., DeBeaufort C. and Schoenle E.J. (2009). Ovaries and female phenotype in a girl with 46, XY karyotype and mutations in the CBX2 gene. Am. J. Hum. Genet. 84, 658-663.
    • (2009) Am. J. Hum. Genet. , vol.84 , pp. 658-663
    • Biason-Lauber, A.1    Konrad, D.2    Meyer, M.3    DeBeaufort, C.4    Schoenle, E.J.5
  • 37
    • 35448952936 scopus 로고    scopus 로고
    • Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice
    • Bouma G.J., Washburn L.L., Albrecht K.H. and Eicher E.M. (2007). Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice. Proc. Natl. Acad. Sci. USA 104, 14994-14999.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14994-14999
    • Bouma, G.J.1    Washburn, L.L.2    Albrecht, K.H.3    Eicher, E.M.4
  • 40
    • 0345700294 scopus 로고    scopus 로고
    • Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad
    • Brennan J., Tilmann C. and Capel B. (2003). Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad. Genes Dev. 17, 800-810.
    • (2003) Genes Dev. , vol.17 , pp. 800-810
    • Brennan, J.1    Tilmann, C.2    Capel, B.3
  • 41
    • 0035047940 scopus 로고    scopus 로고
    • G protein-coupled prostanoid receptors and the kidney
    • Breyer M.D. and Breyer R.M. (2001). G protein-coupled prostanoid receptors and the kidney. Annu. Rev. Physiol. 63, 579-605.
    • (2001) Annu. Rev. Physiol. , vol.63 , pp. 579-605
    • Breyer, M.D.1    Breyer, R.M.2
  • 43
    • 0035023631 scopus 로고    scopus 로고
    • Spatially dynamic expression of Sry in mouse genital ridges
    • Bullejos M. and Koopman P. (2001). Spatially dynamic expression of Sry in mouse genital ridges. Dev. Dyn. 221, 201-205.
    • (2001) Dev. Dyn. , vol.221 , pp. 201-205
    • Bullejos, M.1    Koopman, P.2
  • 46
  • 47
    • 0035480007 scopus 로고    scopus 로고
    • Hematopoietic development: A balancing act
    • Cantor A. and Orkin S. (2001). Hematopoietic development: a balancing act. Curr. Opin. Genet. Dev. 11, 513-519.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 513-519
    • Cantor, A.1    Orkin, S.2
  • 48
    • 33750486857 scopus 로고    scopus 로고
    • R-spondin1 tips the balance in sex determination
    • Capel B. (2006). R-spondin1 tips the balance in sex determination. Nat. Genet. 38, 1233-1234.
    • (2006) Nat. Genet. , vol.38 , pp. 1233-1234
    • Capel, B.1
  • 53
    • 49349112654 scopus 로고    scopus 로고
    • Wt1 negatively regulates beta-catenin signaling during testis development
    • Chang H., Gao F., Guillou F., Taketo M.M., Huff V. and Behringer R.R. (2008). Wt1 negatively regulates beta-catenin signaling during testis development. Development 135, 1875-1885.
    • (2008) Development , vol.135 , pp. 1875-1885
    • Chang, H.1    Gao, F.2    Guillou, F.3    Taketo, M.M.4    Huff, V.5    Behringer, R.R.6
  • 57
    • 0032857909 scopus 로고    scopus 로고
    • Genomic organization and embryonic expression of the mouse?broblast growth factor 9 gene
    • Colvin J.S., Feldman B., Nadeau J.H., Goldfarb M. and Ornitz D.M. (1999). Genomic organization and embryonic expression of the mouse? broblast growth factor 9 gene. Dev. Dyn. 216, 72-88.
    • (1999) Dev. Dyn. , vol.216 , pp. 72-88
    • Colvin, J.S.1    Feldman, B.2    Nadeau, J.H.3    Goldfarb, M.4    Ornitz, D.M.5
  • 58
    • 0035937405 scopus 로고    scopus 로고
    • Male-to-female sex reversal in mice lacking fibroblast growth factor 9
    • Colvin J.S., Green R.P., Schmahl J., Capel B. and Ornitz D.M. (2001). Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell 104, 875-889.
    • (2001) Cell , vol.104 , pp. 875-889
    • Colvin, J.S.1    Green, R.P.2    Schmahl, J.3    Capel, B.4    Ornitz, D.M.5
  • 59
    • 78650924037 scopus 로고    scopus 로고
    • A SOX9 duplication and familial 46, XX developmental testicular disorder
    • Cox J.J., Willatt L., Homfray T. and Woods C.G. (2011). A SOX9 duplication and familial 46, XX developmental testicular disorder. N. Engl. J. Med. 364, 91-93.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 91-93
    • Cox, J.J.1    Willatt, L.2    Homfray, T.3    Woods, C.G.4
  • 60
    • 0035312839 scopus 로고    scopus 로고
    • Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
    • Crispino J., Lodish M., Thurberg B., Litovsky S., Collins T., Molkentin J. and Orkin S. (2001). Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 15, 839-844.
    • (2001) Genes Dev. , vol.15 , pp. 839-844
    • Crispino, J.1    Lodish, M.2    Thurberg, B.3    Litovsky, S.4    Collins, T.5    Molkentin, J.6    Orkin, S.7
  • 62
    • 0033708825 scopus 로고    scopus 로고
    • Expression and action of neurotropin-3 and nerve growth factor in embryonic and early postnatal rat testis development
    • Cupp A.S., Kim G.H. and Skinner M.K. (2000). Expression and action of neurotropin-3 and nerve growth factor in embryonic and early postnatal rat testis development. Biol. Reprod. 63, 1617-1628.
    • (2000) Biol. Reprod. , vol.63 , pp. 1617-1628
    • Cupp, A.S.1    Kim, G.H.2    Skinner, M.K.3
  • 63
    • 0035988260 scopus 로고    scopus 로고
    • Testis developmental phenotypes in neurotropin receptor TRKA and TRKC null mutations: Role in formation of seminiferous cords and germ cell survival
    • Cupp A.S., Tessarollo L. and Skinner M.K. (2002). Testis developmental phenotypes in neurotropin receptor TRKA and TRKC null mutations: role in formation of seminiferous cords and germ cell survival. Biol. Reprod. 66, 1838-1845.
    • (2002) Biol. Reprod. , vol.66 , pp. 1838-1845
    • Cupp, A.S.1    Tessarollo, L.2    Skinner, M.K.3
  • 64
    • 0037837127 scopus 로고    scopus 로고
    • Chemotactic role of neurotropin 3 in the embryonic testis that facilitates male sex determination
    • Cupp A.S., Uzumcu M. and Skinner M.K. (2003). Chemotactic role of neurotropin 3 in the embryonic testis that facilitates male sex determination. Biol. Reprod. 68, 2033-2037.
    • (2003) Biol. Reprod. , vol.68 , pp. 2033-2037
    • Cupp, A.S.1    Uzumcu, M.2    Skinner, M.K.3
  • 65
    • 77954181403 scopus 로고    scopus 로고
    • Role of apoptosis and cell proliferation in the testicular dynamics of seasonal breeding mammals: A study in the Iberian mole, Talpa occidentalis
    • Dadhich R.K., Real F.M., Zurita F., Barrionuevo F.J., Burgos M. and Jiménez R. (2010). Role of apoptosis and cell proliferation in the testicular dynamics of seasonal breeding mammals: a study in the Iberian mole, Talpa occidentalis. Biol. Reprod. 83, 83-91.
    • (2010) Biol. Reprod. , vol.83 , pp. 83-91
    • Dadhich, R.K.1    Real, F.M.2    Zurita, F.3    Barrionuevo, F.J.4    Burgos, M.5    Jiménez, R.6
  • 66
    • 1242285636 scopus 로고    scopus 로고
    • Genomic imprinting at the Wt1 gene involves a novel coding transcript (aWt1) that shows deregulation in Wilms' tumours
    • Dallosso A.R., Hancock A.L., Brown K.W., Williams A.C., Jackson S. and Malik K. (2004). Genomic imprinting at the Wt1 gene involves a novel coding transcript (aWt1) that shows deregulation in Wilms' tumours. Hum. Mol. Genet. 13, 405-415.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 405-415
    • Dallosso, A.R.1    Hancock, A.L.2    Brown, K.W.3    Williams, A.C.4    Jackson, S.5    Malik, K.6
  • 68
    • 0033986543 scopus 로고    scopus 로고
    • The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation
    • De Grandi A., Calvari V., Bertini V., Bulfone A., Peverali G., Camerino G., Borsani G. and Guioli S. (2000). The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation. Mech. Dev. 90, 323-326.
    • (2000) Mech. Dev. , vol.90 , pp. 323-326
    • de Grandi, A.1    Calvari, V.2    Bertini, V.3    Bulfone, A.4    Peverali, G.5    Camerino, G.6    Borsani, G.7    Guioli, S.8
  • 69
    • 0014119131 scopus 로고
    • Association of an anatomo-pathological syndrome of male pseudohermaphroditism, Wilms' tumor, parenchymatous nephropathy and XX/XY mosaicism
    • Denys P., Malvaux P., Van Den Berghe H., Tanghe W. and Proesmans W. (1967). Association of an anatomo-pathological syndrome of male pseudohermaphroditism, Wilms' tumor, parenchymatous nephropathy and XX/XY mosaicism. Arch. Fr. Pediatr. 24, 729-739.
    • (1967) Arch. Fr. Pediatr. , vol.24 , pp. 729-739
    • Denys, P.1    Malvaux, P.2    Van Den Berghe, H.3    Tanghe, W.4    Proesmans, W.5
  • 71
    • 0034050638 scopus 로고    scopus 로고
    • Expression and subcellular localization of SF1, SOX9, WT1, and AMH proteins during early human testicular development
    • De Santa Barbara P., Moniot B., Poulat F. and Berta P. (2000). Expression and subcellular localization of SF1, SOX9, WT1, and AMH proteins during early human testicular development. Dev. Dyn. 217, 293-298.
    • (2000) Dev. Dyn. , vol.217 , pp. 293-298
    • De Santa Barbara, P.1    Moniot, B.2    Poulat, F.3    Berta, P.4
  • 72
    • 38049014941 scopus 로고    scopus 로고
    • SRY and the standoff in sex determination
    • DiNapoli L. and Capel B. (2008). SRY and the standoff in sex determination. Mol. Endocrinol. 22, 1-9.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 1-9
    • DiNapoli, L.1    Capel, B.2
  • 73
    • 33646715639 scopus 로고    scopus 로고
    • FGF9 promotes survival of germ cells in the fetal testis
    • DiNapoli L., Batchvarov J. and Capel B. (2006). FGF9 promotes survival of germ cells in the fetal testis. Development 133, 1519-1527.
    • (2006) Development , vol.133 , pp. 1519-1527
    • DiNapoli, L.1    Batchvarov, J.2    Capel, B.3
  • 74
    • 0014775569 scopus 로고
    • A syndrome of pseudo-hermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease
    • Drash A., Sherman F., Hartmann W. and Blizzard R. (1970). A syndrome of pseudo-hermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease. J. Pediatr. 76, 585-593.
    • (1970) J. Pediatr. , vol.76 , pp. 585-593
    • Drash, A.1    Sherman, F.2    Hartmann, W.3    Blizzard, R.4
  • 75
    • 0028356524 scopus 로고
    • Cloning of novel Wilms tumor gene (Wt1) cDNAs; evidence for antisense transcription of Wt1
    • Eccles M.R., Grubb G., Ogawa O., Szeto J. and Reeve A.E. (1994). Cloning of novel Wilms tumor gene (Wt1) cDNAs; evidence for antisense transcription of Wt1. Oncogene 9, 2059-2063.
    • (1994) Oncogene , vol.9 , pp. 2059-2063
    • Eccles, M.R.1    Grubb, G.2    Ogawa, O.3    Szeto, J.4    Reeve, A.E.5
  • 78
    • 0028288951 scopus 로고
    • An SRY-related sequence on the marsupial X chromosome: Implications for the evolution of the mammalian testis-determining gene
    • Foster J.W. and Graves J.A. (1994). An SRY-related sequence on the marsupial X chromosome: implications for the evolution of the mammalian testis-determining gene. Proc. Natl. Acad. Sci. USA 91, 1927-1931.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1927-1931
    • Foster, J.W.1    Graves, J.A.2
  • 80
    • 0033577703 scopus 로고    scopus 로고
    • Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers
    • Fox A., Liew C., Holmes M., Kowalski K., Mackay J. and Crossley M. (1999). Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. EMBO J. 18, 2812-2822.
    • (1999) EMBO J. , vol.18 , pp. 2812-2822
    • Fox, A.1    Liew, C.2    Holmes, M.3    Kowalski, K.4    McKay, J.5    Crossley, M.6
  • 81
    • 33747064675 scopus 로고    scopus 로고
    • The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis
    • Gao F., Maiti S., Alam N., Zhang Z., Deng J.M., Behringer R., Lécureuil C., Guillou F. and Huff V. (2006). The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc. Natl. Acad. Sci. USA 103, 11987-11992.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11987-11992
    • Gao, F.1    Maiti, S.2    Alam, N.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.6    Lécureuil, C.7    Guillou, F.8    Huff, V.9
  • 83
    • 0023181195 scopus 로고
    • Novel non-isotopic in situ hybridization technique detects small (1 kb) unique sequences in routinely G-banded human chromosomes:?ne mapping of N-MYC and BETA-NGF genes
    • Garson J.A., van den Berghe J.A. and Kemshead J.T. (1987). Novel non-isotopic in situ hybridization technique detects small (1 kb) unique sequences in routinely G-banded human chromosomes:?ne mapping of N-MYC and BETA-NGF genes. Nucleic Acids Res. 15, 4761-4770.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 4761-4770
    • Garson, J.A.1    van den Berghe, J.A.2    Kemshead, J.T.3
  • 84
    • 0037143766 scopus 로고    scopus 로고
    • A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination
    • Gasca S., Canizares. J., De Santa Barbara P., Mejean C., Poulat F., Berta P. and Boizet-Bonhoure B. (2002). A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination. Proc. Natl. Acad. Sci. USA 99, 11199-11204.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11199-11204
    • Gasca, S.1    Canizares, J.2    De Santa Barbara, P.3    Mejean, C.4    Poulat, F.5    Berta, P.6    Boizet-Bonhoure, B.7
  • 85
    • 78049340340 scopus 로고    scopus 로고
    • Mutations of the SRY-responsive enhancer of SOX9 are uncommon in XY gonadal dysgenesis
    • Georg I., Bagheri-Fam. S., Knower K.C., Wieacker P., Scherer G. and Harley V.R. (2010). Mutations of the SRY-responsive enhancer of SOX9 are uncommon in XY gonadal dysgenesis. Sex. Dev. 4, 321-325.
    • (2010) Sex. Dev. , vol.4 , pp. 321-325
    • Georg, I.1    Bagheri-Fam, S.2    Knower, K.C.3    Wieacker, P.4    Scherer, G.5    Harley, V.R.6
  • 86
    • 0025098654 scopus 로고
    • Homozygous deletion in Wilms tumours of a zincfinger gene identi?ed by chromosome jumping
    • Gessler M., Poustka A., Cavenee W., Neve R.L., Orkin S.H. and Bruns G.A. (1990). Homozygous deletion in Wilms tumours of a zincfinger gene identi?ed by chromosome jumping. Nature 343, 774-778.
    • (1990) Nature , vol.343 , pp. 774-778
    • Gessler, M.1    Poustka, A.2    Cavenee, W.3    Neve, R.L.4    Orkin, S.H.5    Bruns, G.A.6
  • 87
    • 0030922218 scopus 로고    scopus 로고
    • The nuclear receptor SF-1 mediates sexually dimorphic expression of Müllerian Inhibiting Substance in vivo
    • Giuili G., Shen W. and IngrahAm. H. (1997). The nuclear receptor SF-1 mediates sexually dimorphic expression of Müllerian Inhibiting Substance in vivo. Development 124, 1799-1807.
    • (1997) Development , vol.124 , pp. 1799-1807
    • Giuili, G.1    Shen, W.2    IngrahAm, H.3
  • 88
    • 0028839606 scopus 로고
    • Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action
    • Gnessi L., Emidi A., Jannini E., Carosa E., Maroder M., Arizzi M., Ulisse S. and Spera G. (1995). Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action. J. Cell Biol. 131, 1105-1121.
    • (1995) J. Cell Biol. , vol.131 , pp. 1105-1121
    • Gnessi, L.1    Emidi, A.2    Jannini, E.3    Carosa, E.4    Maroder, M.5    Arizzi, M.6    Ulisse, S.7    Spera, G.8
  • 90
    • 0025328296 scopus 로고
    • A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
    • Gubbay J., Collignon J., Koopman P., Capel B., Economou A., Münsterberg A., Vivian N., Goodfellow P. and Lovell-Badge R. (1990). A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346, 245-250.
    • (1990) Nature , vol.346 , pp. 245-250
    • Gubbay, J.1    Collignon, J.2    Koopman, P.3    Capel, B.4    Economou, A.5    Münsterberg, A.6    Vivian, N.7    Goodfellow, P.8    Lovell-Badge, R.9
  • 91
    • 0035839099 scopus 로고    scopus 로고
    • Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation
    • Hammes A., Guo J., Lutsch G., Leheste J., Landrock D., Ziegler U., Gubler M. and Schedl A. (2001). Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell 106, 319-329.
    • (2001) Cell , vol.106 , pp. 319-329
    • Hammes, A.1    Guo, J.2    Lutsch, G.3    Leheste, J.4    Landrock, D.5    Ziegler, U.6    Gubler, M.7    Schedl, A.8
  • 93
    • 0041852775 scopus 로고    scopus 로고
    • The molecular action and regulation of the testis-determining factors, SRY (sexdetermining region on the and chromosome) and SOX9 [SRYrelated high-mobility group (HMG) box 9]
    • Harley V.R., Clarkson M.J. and Argentaro A. (2003). The molecular action and regulation of the testis-determining factors, SRY (sexdetermining region on the and chromosome) and SOX9 [SRYrelated high-mobility group (HMG) box 9]. Endocr. Rev. 24, 466-487.
    • (2003) Endocr. Rev. , vol.24 , pp. 466-487
    • Harley, V.R.1    Clarkson, M.J.2    Argentaro, A.3
  • 96
    • 0142243109 scopus 로고    scopus 로고
    • Roles of PDGF in animal development
    • Hoch R. and Soriano P. (2003). Roles of PDGF in animal development. Development 130, 4769-4784.
    • (2003) Development , vol.130 , pp. 4769-4784
    • Hoch, R.1    Soriano, P.2
  • 97
    • 0002001380 scopus 로고
    • Possible location of a recessive testis forming gene on 9p24
    • Hoo J., Salafsky I., Lin C. and Pinsky L. (1989). Possible location of a recessive testis forming gene on 9p24. Am. J. Hum. Genet. (Suppl. 45) A78.
    • (1989) Am. J. Hum. Genet. , Issue.SUPPL. 45
    • Hoo, J.1    Salafsky, I.2    Lin, C.3    Pinsky, L.4
  • 98
    • 0035907372 scopus 로고    scopus 로고
    • The human sex-determining gene SRY is a direct target of WT1
    • Hossain A. and Saunders G.F. (2001). The human sex-determining gene SRY is a direct target of WT1. J. Biol. Chem. 276, 16817-16823.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16817-16823
    • Hossain, A.1    Saunders, G.F.2
  • 99
    • 41549115361 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: New (and old) players and new insights
    • Huang H. and He X. (2008). Wnt/beta-catenin signaling: new (and old) players and new insights. Cur. Opin. Cell Biol. 20, 119-125.
    • (2008) Cur. Opin. Cell Biol. , vol.20 , pp. 119-125
    • Huang, H.1    He, X.2
  • 101
    • 0028910107 scopus 로고
    • Identification of a GATA motif in the cardiac alpha-myosin heavy-chain-encoding gene and isolation of a human GATA-4 cDNA
    • Huang W., Cukerman E. and Liew C. (1995). Identification of a GATA motif in the cardiac alpha-myosin heavy-chain-encoding gene and isolation of a human GATA-4 cDNA. Gene 155, 219-223.
    • (1995) Gene , vol.155 , pp. 219-223
    • Huang, W.1    Cukerman, E.2    Liew, C.3
  • 102
    • 0029987045 scopus 로고    scopus 로고
    • Assignment of the human GATA4 gene to 8p23.1->p22 using fluorescence in situ hybridization analysis
    • Huang W., Heng H. and Liew C. (1996). Assignment of the human GATA4 gene to 8p23.1->p22 using fluorescence in situ hybridization analysis. CytoGenet. Cell Genet. 72, 217-218.
    • (1996) CytoGenet. Cell Genet. , vol.72 , pp. 217-218
    • Huang, W.1    Heng, H.2    Liew, C.3
  • 104
    • 0028276035 scopus 로고
    • Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases
    • Ikeda Y., Shen W.H., Ingraham H.A. and Parker K.L. (1994). Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol. Endocrinol. 8, 654-662.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 654-662
    • Ikeda, Y.1    Shen, W.H.2    Ingraham, H.A.3    Parker, K.L.4
  • 106
    • 0035079932 scopus 로고    scopus 로고
    • Comparative localization of DAX-1 and Ad4BP/SF-1 during development of the hypothalamic-pituitarygonadal axis suggests their closely related and distinct functions
    • Ikeda Y., Takeda Y., Shikayama T., Mukai T., Hisano S. and Morohashi K.I. (2001). Comparative localization of DAX-1 and Ad4BP/SF-1 during development of the hypothalamic-pituitarygonadal axis suggests their closely related and distinct functions. Dev. Dyn. 220, 363-376.
    • (2001) Dev. Dyn. , vol.220 , pp. 363-376
    • Ikeda, Y.1    Takeda, Y.2    Shikayama, T.3    Mukai, T.4    Hisano, S.5    Morohashi, K.I.6
  • 107
    • 0025258480 scopus 로고
    • A human XY female with a frame shift mutation in the candidate testisdetermining gene SRY
    • Jäger R.J., Anvret M., Hall K. and Scherer G. (1990). A human XY female with a frame shift mutation in the candidate testisdetermining gene SRY. Nature 348, 452-454.
    • (1990) Nature , vol.348 , pp. 452-454
    • Jäger, R.J.1    Anvret, M.2    Hall, K.3    Scherer, G.4
  • 109
    • 0041508536 scopus 로고    scopus 로고
    • Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad
    • Jeays-Ward K., Hoyle C., Brennan J., Dandonneau M., Alldus G., Capel B. and Swain A. (2003). Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad. Development 130, 3663-3670.
    • (2003) Development , vol.130 , pp. 3663-3670
    • Jeays-Ward, K.1    Hoyle, C.2    Brennan, J.3    Dandonneau, M.4    Alldus, G.5    Capel, B.6    Swain, A.7
  • 110
    • 10044235047 scopus 로고    scopus 로고
    • Wnt4 is required for proper male as well as female sexual development
    • Jeays-Ward K., Dandonneau M. and Swain A. (2004). Wnt4 is required for proper male as well as female sexual development. Dev. Biol. 276, 431-440.
    • (2004) Dev. Biol. , vol.276 , pp. 431-440
    • Jeays-Ward, K.1    Dandonneau, M.2    Swain, A.3
  • 111
    • 77949304854 scopus 로고    scopus 로고
    • Ovarian organogenesis in mammals: Mice cannot tell us everything
    • Jiménez R. (2009). Ovarian organogenesis in mammals: mice cannot tell us everything. Sex. Dev. 3, 291-301.
    • (2009) Sex. Dev. , vol.3 , pp. 291-301
    • Jiménez, R.1
  • 112
    • 0344043347 scopus 로고    scopus 로고
    • Mammalian sex determination: Joining pieces of the genetic puzzle
    • Jiménez R. and Burgos M. (1998). Mammalian sex determination: joining pieces of the genetic puzzle. Bioessays 20, 696-699.
    • (1998) Bioessays , vol.20 , pp. 696-699
    • Jiménez, R.1    Burgos, M.2
  • 115
    • 0141591505 scopus 로고    scopus 로고
    • Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy
    • Jordan B.K., Shen J.H., Olaso R., Ingraham. H.A. and Vilain E. (2003). Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy. Proc. Natl. Acad. Sci. USA 100, 10866-10871.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10866-10871
    • Jordan, B.K.1    Shen, J.H.2    Olaso, R.3    Ingraham, H.A.4    Vilain, E.5
  • 116
    • 0001664017 scopus 로고
    • Recherches sur la differenciation sexuelle de l'embryon de lapin
    • Jost A. (1947). Recherches sur la differenciation sexuelle de l'embryon de lapin. Arch. Anat. Microsc. Morphol. Exp. 36, 271-315.
    • (1947) Arch. Anat. Microsc. Morphol. Exp. , vol.36 , pp. 271-315
    • Jost, A.1
  • 117
    • 0000009634 scopus 로고
    • Problems of fetal endocrinology: The gonadal and the hypophyseal hormones
    • Jost A. (1953). Problems of fetal endocrinology: the gonadal and the hypophyseal hormones. Recent Prog. Horm. Res. 8, 379-418.
    • (1953) Recent Prog. Horm. Res. , vol.8 , pp. 379-418
    • Jost, A.1
  • 118
    • 0010365655 scopus 로고
    • The prenatal development of bovine freemartins
    • Reinborn R. (ed). Springer-Verlag. Berlin
    • Jost A., Perchellet J., Prepin J. and Vigier B. (1975). The prenatal development of bovine freemartins. In: Symposium on intersexuality. Reinborn R. (ed). Springer-Verlag. Berlin. pp 392-406.
    • (1975) Symposium on intersexuality , pp. 392-406
    • Jost, A.1    Perchellet, J.2    Prepin, J.3    Vigier, B.4
  • 119
    • 1642300426 scopus 로고    scopus 로고
    • R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants
    • Kamata T., Katsube K.I., Michikawa M., Yamada M., Takada S. and Mizusawa H. (2004). R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Biochim. Biophys. Acta 1676, 51-62.
    • (2004) Biochim. Biophys. Acta , vol.1676 , pp. 51-62
    • Kamata, T.1    Katsube, K.I.2    Michikawa, M.3    Yamada, M.4    Takada, S.5    Mizusawa, H.6
  • 121
    • 0032774661 scopus 로고    scopus 로고
    • Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle
    • Karlsson L., Bondjers C. and Betsholtz C. (1999). Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development 126, 2611-2621.
    • (1999) Development , vol.126 , pp. 2611-2621
    • Karlsson, L.1    Bondjers, C.2    Betsholtz, C.3
  • 122
    • 0033832891 scopus 로고    scopus 로고
    • Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) de?cient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis
    • Karlsson L., Lindahl P., Heath J. and Betsholtz C. (2000). Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) de?cient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development 127, 3457-3466.
    • (2000) Development , vol.127 , pp. 3457-3466
    • Karlsson, L.1    Lindahl, P.2    Heath, J.3    Betsholtz, C.4
  • 123
    • 78649823499 scopus 로고    scopus 로고
    • Sry: The master switch in mammalian sex determination
    • Kashimada K. and Koopman P. (2010). Sry: the master switch in mammalian sex determination. Development 137, 3921-3930.
    • (2010) Development , vol.137 , pp. 3921-3930
    • Kashimada, K.1    Koopman, P.2
  • 124
    • 78650840062 scopus 로고    scopus 로고
    • FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development
    • Kashimada K., Pelosi E., Chen H., Schlessinger D., Wilhelm D. and Koopman P. (2011). FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology 152, 272-280.
    • (2011) Endocrinology , vol.152 , pp. 272-280
    • Kashimada, K.1    Pelosi, E.2    Chen, H.3    Schlessinger, D.4    Wilhelm, D.5    Koopman, P.6
  • 128
    • 0036739521 scopus 로고    scopus 로고
    • Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis
    • Ketola I., Anttonen M., Vaskivuo T., Tapanainen J., Toppari J. and Heikinheimo M. (2002). Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis. Eur. J. Endocrinol. 147, 397-406.
    • (2002) Eur. J. Endocrinol. , vol.147 , pp. 397-406
    • Ketola, I.1    Anttonen, M.2    Vaskivuo, T.3    Tapanainen, J.4    Toppari, J.5    Heikinheimo, M.6
  • 129
    • 33748313401 scopus 로고    scopus 로고
    • Balancing the bipotential gonad between alternative organ fates: A new perspective on an old problem
    • Kim Y. and Capel B. (2006). Balancing the bipotential gonad between alternative organ fates: a new perspective on an old problem. Dev. Dyn. 235, 2292-2300.
    • (2006) Dev. Dyn. , vol.235 , pp. 2292-2300
    • Kim, Y.1    Capel, B.2
  • 130
    • 0032981181 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor gene (Wt1) product regulates Dax-1 gene expression during gonadal differentiation
    • Kim J., Prawitt D., Bardeesy N., Torban E., Vicaner C., Goodyer P., Zabel B. and Pelletier J. (1999). The Wilms' tumor suppressor gene (Wt1) product regulates Dax-1 gene expression during gonadal differentiation. Mol. Cell. Biol. 19, 2289-2299.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2289-2299
    • Kim, J.1    Prawitt, D.2    Bardeesy, N.3    Torban, E.4    Vicaner, C.5    Goodyer, P.6    Zabel, B.7    Pelletier, J.8
  • 131
    • 0037347326 scopus 로고    scopus 로고
    • Sexually dimorphic expression of multiple doublesexrelated genes in the embryonic mouse gonad
    • Kim S., Kettlewell J., Anderson R., Bardwell V. and Zarkower D. (2003). Sexually dimorphic expression of multiple doublesexrelated genes in the embryonic mouse gonad. Gene Expr. Patterns 3, 77-82.
    • (2003) Gene Expr. Patterns , vol.3 , pp. 77-82
    • Kim, S.1    Kettlewell, J.2    Anderson, R.3    Bardwell, V.4    Zarkower, D.5
  • 134
  • 135
    • 0025243412 scopus 로고
    • Expression of a candidate sex-determining gene during mouse testis differentiation
    • Koopman P., Münsterberg A., Capel B., Vivian N. and Lovell-Badge R. (1990). Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 348, 450-452.
    • (1990) Nature , vol.348 , pp. 450-452
    • Koopman, P.1    Münsterberg, A.2    Capel, B.3    Vivian, N.4    Lovell-Badge, R.5
  • 136
    • 0025877323 scopus 로고
    • Male development of chromosomally female mice transgenic for Sry
    • Koopman P., Gubbay J., Vivian N., Goodfellow P. and Lovell-Badge R. (1991). Male development of chromosomally female mice transgenic for Sry. Nature 351, 117-121.
    • (1991) Nature , vol.351 , pp. 117-121
    • Koopman, P.1    Gubbay, J.2    Vivian, N.3    Goodfellow, P.4    Lovell-Badge, R.5
  • 140
    • 0034710898 scopus 로고    scopus 로고
    • Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein
    • Laity J.H., Dyson H.J. and Wright P.E. (2000). Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein. Proc. Natl. Acad. Sci. USA 97, 11932-11935.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11932-11935
    • Laity, J.H.1    Dyson, H.J.2    Wright, P.E.3
  • 143
    • 0345732638 scopus 로고    scopus 로고
    • GATA4 regulates testis expression of Dmrt1
    • Lei N. and Heckert L. (2004). GATA4 regulates testis expression of Dmrt1. Mol. Cell. Biol. 24, 377-388.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 377-388
    • Lei, N.1    Heckert, L.2
  • 145
    • 0033980930 scopus 로고    scopus 로고
    • Role of neurotropins in rat embryonic testis morphogenesis (cord formation)
    • Levine E., Cupp A.S. and Skinner M.K. (2000). Role of neurotropins in rat embryonic testis morphogenesis (cord formation). Biol. Reprod. 62, 132-142.
    • (2000) Biol. Reprod. , vol.62 , pp. 132-142
    • Levine, E.1    Cupp, A.S.2    Skinner, M.K.3
  • 146
    • 0035891369 scopus 로고    scopus 로고
    • Overexpression of PDGF-A in the lung epithelium of transgenic mice produces a lethal phenotype associated with hyperplasia of mesenchymal cells
    • Li J. and Hoyle G. (2001). Overexpression of PDGF-A in the lung epithelium of transgenic mice produces a lethal phenotype associated with hyperplasia of mesenchymal cells. Dev. Biol. 239, 338-349.
    • (2001) Dev. Biol. , vol.239 , pp. 338-349
    • Li, J.1    Hoyle, G.2
  • 147
    • 55749088979 scopus 로고    scopus 로고
    • Steroidogenic factor-1 (SF-1, Ad4BP, NR5A1) and disorders of testis development
    • Lin L. and Achermann J.C. (2008). Steroidogenic factor-1 (SF-1, Ad4BP, NR5A1) and disorders of testis development. Sex. Dev. 2, 200-209.
    • (2008) Sex. Dev. , vol.2 , pp. 200-209
    • Lin, L.1    Achermann, J.C.2
  • 148
    • 11244331302 scopus 로고    scopus 로고
    • The N termini of friend of GATA (FOG) proteins de?ne a novel transcriptional repression motif and a superfamily of transcriptional repressors
    • Lin A., Roche A., Wilk J. and Svensson E. (2004). The N termini of friend of GATA (FOG) proteins de?ne a novel transcriptional repression motif and a superfamily of transcriptional repressors. J. Biol. Chem. 279, 55017-55023.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55017-55023
    • Lin, A.1    Roche, A.2    Wilk, J.3    Svensson, E.4
  • 149
    • 58749112778 scopus 로고    scopus 로고
    • Sex-speci?c roles of beta-catenin in mouse gonadal development
    • Liu C., Bingham. N., Parker K. and Yao H.H. (2009). Sex-speci?c roles of beta-catenin in mouse gonadal development. Hum. Mol. Genet. 18, 405-417.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 405-417
    • Liu, C.1    Bingham, N.2    Parker, K.3    Yao, H.H.4
  • 151
    • 1842418671 scopus 로고    scopus 로고
    • Sex determination: A 'window' of DAX1 activity
    • Ludbrook L.M. and Harley V.R. (2004). Sex determination: a 'window' of DAX1 activity. Trends Endocrinol. Metab. 15, 116-121.
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 116-121
    • Ludbrook, L.M.1    Harley, V.R.2
  • 152
    • 0028303959 scopus 로고
    • A cell-speci?c nuclear receptor is essential for adrenal and gonadal development and sexual differentiation
    • Luo X., Ikeda Y. and Parker K.L. (1994). A cell-speci?c nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77, 481-490.
    • (1994) Cell , vol.77 , pp. 481-490
    • Luo, X.1    Ikeda, Y.2    Parker, K.L.3
  • 157
    • 59149105257 scopus 로고    scopus 로고
    • Ovarian development in mice requires the GATA4-FOG2 transcription complex
    • Manuylov N.L., Smagulova F.O., Leach L. and Tevosian S.G. (2008). Ovarian development in mice requires the GATA4-FOG2 transcription complex. Development 135, 3731-3743.
    • (2008) Development , vol.135 , pp. 3731-3743
    • Manuylov, N.L.1    Smagulova, F.O.2    Leach, L.3    Tevosian, S.G.4
  • 158
    • 0019497899 scopus 로고
    • Genetics of Wilms' tumor
    • Matsunaga E. (1981). Genetics of Wilms' tumor. Hum. Genet. 57, 231-246.
    • (1981) Hum. Genet. , vol.57 , pp. 231-246
    • Matsunaga, E.1
  • 163
    • 0036952330 scopus 로고    scopus 로고
    • Sexually dimorphic gene expression in the developing mouse gonad
    • Menke D.B. and Page D.C. (2002). Sexually dimorphic gene expression in the developing mouse gonad. Gene. Expr. Patterns 2, 359-367.
    • (2002) Gene. Expr. Patterns , vol.2 , pp. 359-367
    • Menke, D.B.1    Page, D.C.2
  • 164
    • 0026010220 scopus 로고
    • Testicular differentiation in mammals under normal and experimental conditions
    • Merchant-Larios H. and Taketo T. (1975). Testicular differentiation in mammals under normal and experimental conditions. J. Electr. Microsc. Tech. 19, 158-171.
    • (1975) J. Electr. Microsc. Tech. , vol.19 , pp. 158-171
    • Merchant-Larios, H.1    Taketo, T.2
  • 167
    • 0029658831 scopus 로고    scopus 로고
    • Genetic analysis of the Müllerianinhibiting substance signal transduction pathway in mammalian sexual differentiation
    • Mishina Y., Rey R., Finegold M.J., Matzuk M.M., Josso N., Cate R.L. and Behringer R.R. (1996). Genetic analysis of the Müllerianinhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev. 10, 2577-2587.
    • (1996) Genes Dev. , vol.10 , pp. 2577-2587
    • Mishina, Y.1    Rey, R.2    Finegold, M.J.3    Matzuk, M.M.4    Josso, N.5    Cate, R.L.6    Behringer, R.R.7
  • 168
    • 0027155561 scopus 로고
    • Molecular cloning of a novel cytokine cDNA encoding the ninth member of the? broblast growth factor family, which has a unique secretion property
    • Miyamoto M., Naruo K., Seko C., Matsumoto S., Kondo T. and Kurokawa T. (1993). Molecular cloning of a novel cytokine cDNA encoding the ninth member of the? broblast growth factor family, which has a unique secretion property. Mol. Cell. Biol. 13, 4251-4259.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4251-4259
    • Miyamoto, M.1    Naruo, K.2    Seko, C.3    Matsumoto, S.4    Kondo, T.5    Kurokawa, T.6
  • 170
    • 0037383725 scopus 로고    scopus 로고
    • Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) gene transcription is regulated by WNT4 in the female developing gonad
    • Mizusaki H., Kawabe K., Mukai T., Ariyoshi E., Kasahara M., Yoshioka H., SwainA. and Morohashi K. (2003). Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) gene transcription is regulated by WNT4 in the female developing gonad. Mol. Endocrinol. 17, 507-519.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 507-519
    • Mizusaki, H.1    Kawabe, K.2    Mukai, T.3    Ariyoshi, E.4    Kasahara, M.5    Yoshioka, H.6    Swain, A.7    Morohashi, K.8
  • 171
    • 0033998008 scopus 로고    scopus 로고
    • Male specific expression suggests role of DMRT1 in human sex determination
    • Moniot B., Berta P., Scherer G., Südbeck P. and Poulat F. (2000). Male specific expression suggests role of DMRT1 in human sex determination. Mech. Dev. 91, 323-325.
    • (2000) Mech. Dev. , vol.91 , pp. 323-325
    • Moniot, B.1    Berta, P.2    Scherer, G.3    Südbeck, P.4    Poulat, F.5
  • 173
    • 0023477994 scopus 로고
    • Chronic renal failure and XY gonadal dysgenesis: "Frasier" syndrome-a commentary on reported cases
    • Moorthy A., Chesney R. and Lubinsky M. (1987). Chronic renal failure and XY gonadal dysgenesis: "Frasier" syndrome-a commentary on reported cases. Am. J. Med. Genet. Suppl. 3, 297-302.
    • (1987) Am. J. Med. Genet. Suppl. , vol.3 , pp. 297-302
    • Moorthy, A.1    Chesney, R.2    Lubinsky, M.3
  • 174
    • 0029742909 scopus 로고    scopus 로고
    • Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
    • Morais da Silva S., Hacker A., Harley V., Goodfellow P., Swain A. and Lovell-Badge R. (1996). Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nature Genet. 14, 62-68.
    • (1996) Nature Genet. , vol.14 , pp. 62-68
    • Morais da Silva, S.1    Hacker, A.2    Harley, V.3    Goodfellow, P.4    Swain, A.5    Lovell-Badge, R.6
  • 176
    • 0027378413 scopus 로고
    • Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues
    • Mundlos S., Pelletier J., Darveau A., Bachmann M., Winterpacht A. and Zabel B. (1993). Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. Development 119, 1329-1341.
    • (1993) Development , vol.119 , pp. 1329-1341
    • Mundlos, S.1    Pelletier, J.2    Darveau, A.3    Bachmann, M.4    Winterpacht, A.5    Zabel, B.6
  • 177
    • 0025950803 scopus 로고
    • Expression of the mouse anti-Müllerian hormone gene suggests a role in both male and female sexual differentiation
    • Münsterberg A. and Lovell-Badge R. (1991). Expression of the mouse anti-Müllerian hormone gene suggests a role in both male and female sexual differentiation. Development 113, 613-624.
    • (1991) Development , vol.113 , pp. 613-624
    • Münsterberg, A.1    Lovell-Badge, R.2
  • 179
    • 0032076964 scopus 로고    scopus 로고
    • Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression
    • Nachtigal M., Hirokawa Y., Enyeart-VanHouten D., Flanagan J., Hammer G. and Ingrahm. H. (1998). Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell 93, 445-454.
    • (1998) Cell , vol.93 , pp. 445-454
    • Nachtigal, M.1    Hirokawa, Y.2    Enyeart-VanHouten, D.3    Flanagan, J.4    Hammer, G.5    Ingrahm, H.6
  • 180
    • 33744964431 scopus 로고    scopus 로고
    • Mouse Cristin/R-spondin family proteins are novel ligands for the frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • Nam. J., Turcotte T.J., Smith P.F., Choi S. and Yoon J.K. (2006). Mouse Cristin/R-spondin family proteins are novel ligands for the frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J. Biol. Chem. 281, 13247-13257.
    • (2006) J. Biol. Chem. , vol.281 , pp. 13247-13257
    • Nam, J.1    Turcotte, T.J.2    Smith, P.F.3    Choi, S.4    Yoon, J.K.5
  • 190
    • 0033808669 scopus 로고    scopus 로고
    • Deletions of 9p and the quest for a conserved mechanism of sex determination
    • Ottolenghi C. and McElreavey K. (2000). Deletions of 9p and the quest for a conserved mechanism of sex determination. Mol. Genet. Metab. 71, 397-404.
    • (2000) Mol. Genet. Metab. , vol.71 , pp. 397-404
    • Ottolenghi, C.1    McElreavey, K.2
  • 191
    • 0036193087 scopus 로고    scopus 로고
    • Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination
    • Ottolenghi C., Fellous M., Barbieri M. and McElreavey K. (2002). Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. Genomics 79, 333-343.
    • (2002) Genomics , vol.79 , pp. 333-343
    • Ottolenghi, C.1    Fellous, M.2    Barbieri, M.3    McElreavey, K.4
  • 194
    • 21044446418 scopus 로고    scopus 로고
    • Nuclear receptors SF1 and DAX1 function cooperatively to mediate somatic cell differentiation during testis development
    • Park S.Y., Meeks J.J., Raverot G., Pfaff L.E., Weiss J., Hammer G.D. and Jameson J.L. (2005). Nuclear receptors SF1 and DAX1 function cooperatively to mediate somatic cell differentiation during testis development. Development 132, 2415-2423.
    • (2005) Development , vol.132 , pp. 2415-2423
    • Park, S.Y.1    Meeks, J.J.2    Raverot, G.3    Pfaff, L.E.4    Weiss, J.5    Hammer, G.D.6    Jameson, J.L.7
  • 197
    • 0036668278 scopus 로고    scopus 로고
    • The GATA family (vertebrates and invertebrates)
    • Patient R. and McGhee J. (2002). The GATA family (vertebrates and invertebrates). Curr. Opin. Genet. Dev. 12, 416-422.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 416-422
    • Patient, R.1    McGhee, J.2
  • 198
    • 0034718796 scopus 로고    scopus 로고
    • Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
    • Pellegrini L., Burke D.F., van Delft F., Mulloy B. and Blundell T.L. (2001). Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature 407, 1029-1034.
    • (2001) Nature , vol.407 , pp. 1029-1034
    • Pellegrini, L.1    Burke, D.F.2    van Delft, F.3    Mulloy, B.4    Blundell, T.L.5
  • 200
    • 0017236069 scopus 로고
    • Congenital anomalies in children with Wilms' tumor: A new survey
    • Pendergrass T. (1976). Congenital anomalies in children with Wilms' tumor: a new survey. Cancer 37, 403-408.
    • (1976) Cancer , vol.37 , pp. 403-408
    • Pendergrass, T.1
  • 201
    • 0033358653 scopus 로고    scopus 로고
    • Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: Evidence for an extended control region
    • Pfeifer D., Kist R., Dewar K., Devon K., Lander E.S., Birren B., Korniszewski L., Back E. and Scherer G. (1999). Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: evidence for an extended control region. Am. J. Hum. Genet. 65, 111-124.
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 111-124
    • Pfeifer, D.1    Kist, R.2    Dewar, K.3    Devon, K.4    Lander, E.S.5    Birren, B.6    Korniszewski, L.7    Back, E.8    Scherer, G.9
  • 202
    • 0033995606 scopus 로고    scopus 로고
    • The SOX8 gene is located within 700 kb of the tip of chromosome 16p and is deleted in a patient with ATR-16 syndrome
    • Pfeifer D., Poulat F., Holinski-Feder E., Kooy F. and Scherer G. (2000). The SOX8 gene is located within 700 kb of the tip of chromosome 16p and is deleted in a patient with ATR-16 syndrome. Genomics 63, 108-116.
    • (2000) Genomics , vol.63 , pp. 108-116
    • Pfeifer, D.1    Poulat, F.2    Holinski-Feder, E.3    Kooy, F.4    Scherer, G.5
  • 205
    • 77949876407 scopus 로고    scopus 로고
    • Sox10 gain-of-function causes XX sex reversal in mice: Implications for human 22q-linked disorders of sex development
    • Polanco J.C., Wilhelm D., Davidson T., Knight D. and Koopman P. (2010). Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development. Hum. Mol. Genet. 19, 506-516.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 506-516
    • Polanco, J.C.1    Wilhelm, D.2    Davidson, T.3    Knight, D.4    Koopman, P.5
  • 207
    • 0031660707 scopus 로고    scopus 로고
    • The SOX10/Sox10 gene from human and mouse: Sequence, expression, and transactivation by the encoded HMG domain transcription factor
    • Pusch C., Hustert E., Pfeifer D., Südbeck P., Kist R., Roe B., Wang Z., Balling R., Blin N. and Scherer G. (1998). The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor. Hum. Genet. 103, 115-123.
    • (1998) Hum. Genet. , vol.103 , pp. 115-123
    • Pusch, C.1    Hustert, E.2    Pfeifer, D.3    Südbeck, P.4    Kist, R.5    Roe, B.6    Wang, Z.7    Balling, R.8    Blin, N.9    Scherer, G.10
  • 208
    • 18144402886 scopus 로고    scopus 로고
    • Sox9 is sufficient for functional testis development producing fertile male mice in the absence of Sry
    • Qin Y. and Bishop C.E. (2005). Sox9 is sufficient for functional testis development producing fertile male mice in the absence of Sry. Hum. Mol. Genet. 14, 1221-1229.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1221-1229
    • Qin, Y.1    Bishop, C.E.2
  • 210
    • 23844540300 scopus 로고    scopus 로고
    • Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice
    • Ragolia L., Palaia T., Hall C.E., Maesaka J.K., Eguchi N. and Urade Y. (2005). Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice. J. Biol. Chem. 280, 29946-29955.
    • (2005) J. Biol. Chem. , vol.280 , pp. 29946-29955
    • Ragolia, L.1    Palaia, T.2    Hall, C.E.3    Maesaka, J.K.4    Eguchi, N.5    Urade, Y.6
  • 212
    • 0033571276 scopus 로고    scopus 로고
    • Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development
    • Raymond C., Kettlewell J., Hirsch B., Bardwell V. and Zarkower D. (1999a). Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development. Dev. Biol. 215, 208-220.
    • (1999) Dev. Biol. , vol.215 , pp. 208-220
    • Raymond, C.1    Kettlewell, J.2    Hirsch, B.3    Bardwell, V.4    Zarkower, D.5
  • 214
    • 0034668046 scopus 로고    scopus 로고
    • Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
    • Raymond C., Murphy M., O'Sullivan M., Bardwell V. and Zarkower D. (2000). Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 14, 2587-2595.
    • (2000) Genes Dev. , vol.14 , pp. 2587-2595
    • Raymond, C.1    Murphy, M.2    O'Sullivan, M.3    Bardwell, V.4    Zarkower, D.5
  • 215
    • 0017883401 scopus 로고
    • Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion
    • Riccardi V., Sujansky E., Smith A. and Francke U. (1978). Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion. Pediatrics 61, 604-610.
    • (1978) Pediatrics , vol.61 , pp. 604-610
    • Riccardi, V.1    Sujansky, E.2    Smith, A.3    Francke, U.4
  • 216
    • 3442887352 scopus 로고    scopus 로고
    • Embryonic mouse testis development: Role of platelet derived growth factor (PDGF-BB)
    • Ricci G., Catizone A. and Galdieri M. (2004). Embryonic mouse testis development: role of platelet derived growth factor (PDGF-BB). J. Cell. Physiol. 200, 458-467.
    • (2004) J. Cell. Physiol. , vol.200 , pp. 458-467
    • Ricci, G.1    Catizone, A.2    Galdieri, M.3
  • 217
    • 0041381351 scopus 로고    scopus 로고
    • The human fetal testis is a site of expression of neurotrophins and their receptors: Regulation of the germ cell and peritubular cell population
    • Robinson L.L.L., Townsend J. and Anderson R.A. (2003). The human fetal testis is a site of expression of neurotrophins and their receptors: regulation of the germ cell and peritubular cell population. J. Clin. Endocrinol. Metab. 88, 3943-3951.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 3943-3951
    • Robinson, L.L.L.1    Townsend, J.2    Anderson, R.A.3
  • 219
    • 54949097010 scopus 로고    scopus 로고
    • New insights into SRY regulation through identi?cation of 5' conserved sequences
    • Ross D.G.F., Bowles J., Koopman P. and Lehnert S. (2008). New insights into SRY regulation through identi?cation of 5' conserved sequences. BMC Mol. Biol. 9, 85.
    • (2008) BMC Mol. Biol. , vol.9 , pp. 85
    • Ross, D.G.F.1    Bowles, J.2    Koopman, P.3    Lehnert, S.4
  • 220
    • 0033551774 scopus 로고    scopus 로고
    • Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties
    • Scharnhorst V., Dekker P., van der Eb A.J. and Jochemsen A.G. (1999). Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties. J. Biol. Chem. 274, 23456-23462.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23456-23462
    • Scharnhorst, V.1    Dekker, P.2    van der Eb, A.J.3    Jochemsen, A.G.4
  • 221
    • 0041845263 scopus 로고    scopus 로고
    • SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro
    • Schepers G.E., Wilson M., Wilhelm D. and Koopman P. (2003). SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro. J. Biol. Chem. 278, 28101-28108.
    • (2003) J. Biol. Chem. , vol.278 , pp. 28101-28108
    • Schepers, G.E.1    Wilson, M.2    Wilhelm, D.3    Koopman, P.4
  • 222
    • 1342327343 scopus 로고    scopus 로고
    • The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance
    • Schmidt D., Ovitt C.E., Anlag K., Fehsenfeld S., Gredsted L., Treier A. and Treier M. (2004). The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance. Development 131, 933-942.
    • (2004) Development , vol.131 , pp. 933-942
    • Schmidt, D.1    Ovitt, C.E.2    Anlag, K.3    Fehsenfeld, S.4    Gredsted, L.5    Treier, A.6    Treier, M.7
  • 224
    • 45149093155 scopus 로고    scopus 로고
    • Sex determination involves synergistic action of SRY and SF1 on a speci?c Sox9 enhancer
    • Sekido R. and Lovell-Badge R. (2008). Sex determination involves synergistic action of SRY and SF1 on a speci?c Sox9 enhancer. Nature 453, 930-934.
    • (2008) Nature , vol.453 , pp. 930-934
    • Sekido, R.1    Lovell-Badge, R.2
  • 226
    • 18844411825 scopus 로고    scopus 로고
    • Variability of sexual phenotype in 46, XX(SRY+). patients: The in?uence of spreading X inactivation versus position effects
    • Sharp A., Kusz K., Jaruzelska J., Tapper W., Szarras-Czapnik M., Wolski J. and Jacobs P. (2005). Variability of sexual phenotype in 46, XX(SRY+). patients: the in?uence of spreading X inactivation versus position effects. J. Med. Genet. 42, 420-427.
    • (2005) J. Med. Genet. , vol.42 , pp. 420-427
    • Sharp, A.1    Kusz, K.2    Jaruzelska, J.3    Tapper, W.4    Szarras-Czapnik, M.5    Wolski, J.6    Jacobs, P.7
  • 227
    • 0028308118 scopus 로고
    • Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: A link to the sex determination cascade
    • Shen W.H., Moore C.C., Ikeda Y., Parker K.L. and Ingraham. H.A. (1994). Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: a link to the sex determination cascade. Cell 77, 651-661.
    • (1994) Cell , vol.77 , pp. 651-661
    • Shen, W.H.1    Moore, C.C.2    Ikeda, Y.3    Parker, K.L.4    Ingraham, H.A.5
  • 228
    • 0031417853 scopus 로고    scopus 로고
    • The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor
    • Shimamura R., Fraizer G.C., Trapman J., Lau Y.C. and Saunders G. (1997). The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor. Clin. Cancer Res. 3, 2571-2580.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2571-2580
    • Shimamura, R.1    Fraizer, G.C.2    Trapman, J.3    Lau, Y.C.4    Saunders, G.5
  • 230
    • 71149084102 scopus 로고    scopus 로고
    • Females battle to suppress their inner male
    • Sinclair A. and Smith C. (2009). Females battle to suppress their inner male. Cell 139, 1051-1053.
    • (2009) Cell , vol.139 , pp. 1051-1053
    • Sinclair, A.1    Smith, C.2
  • 232
  • 234
    • 0034807930 scopus 로고    scopus 로고
    • Idiopathic weight reduction in mice de?cient in the highmobility-group transcription factor Sox8
    • Sock E., Schmidt K., Hermanns-Borgmeyer I., Bösl M.R. and Wegner M. (2001). Idiopathic weight reduction in mice de?cient in the highmobility-group transcription factor Sox8. Mol. Cel. Biol. 21, 6951-6959.
    • (2001) Mol. Cel. Biol. , vol.21 , pp. 6951-6959
    • Sock, E.1    Schmidt, K.2    Hermanns-Borgmeyer, I.3    Bösl, M.R.4    Wegner, M.5
  • 235
    • 0038039240 scopus 로고    scopus 로고
    • Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia
    • Sock E., Pagon R.A., Keymolen K., Lissens W., Wegner M. and Scherer G. (2003). Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia. Hum. Mol. Genet. 12, 1439-1447.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1439-1447
    • Sock, E.1    Pagon, R.A.2    Keymolen, K.3    Lissens, W.4    Wegner, M.5    Scherer, G.6
  • 238
    • 0037663384 scopus 로고    scopus 로고
    • The SOX9 transcription factor determines glial fate choice in the developing spinal cord
    • Stolt C.C., Lommes P., Sock E., Chaboissier M., Schedl A. and Wegner M. (2003). The SOX9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 17, 1677-1689.
    • (2003) Genes Dev. , vol.17 , pp. 1677-1689
    • Stolt, C.C.1    Lommes, P.2    Sock, E.3    Chaboissier, M.4    Schedl, A.5    Wegner, M.6
  • 239
    • 79952109036 scopus 로고    scopus 로고
    • Ontogenesis of testis development and function in humans
    • Stukenborg J.B., Colón E. and Söder O. (2010). Ontogenesis of testis development and function in humans. Sex. Dev. 4, 199-212.
    • (2010) Sex. Dev. , vol.4 , pp. 199-212
    • Stukenborg, J.B.1    Colón, E.2    Söder, O.3
  • 240
    • 0142164604 scopus 로고    scopus 로고
    • Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9
    • Südbeck P. and Scherer G. (1997). Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9. J. Biol. Chem. 272, 27848-27852.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27848-27852
    • Südbeck, P.1    Scherer, G.2
  • 241
    • 0029977067 scopus 로고    scopus 로고
    • Sex reversal by loss of the C-terminal transactivation domain of human SOX9
    • Südbeck P., Schmitz M.L., Baeuerle P.A. and Scherer G. (1996). Sex reversal by loss of the C-terminal transactivation domain of human SOX9. Nat. Genet. 13, 230-232.
    • (1996) Nat. Genet. , vol.13 , pp. 230-232
    • Südbeck, P.1    Schmitz, M.L.2    Baeuerle, P.A.3    Scherer, G.4
  • 242
    • 0033678523 scopus 로고    scopus 로고
    • A human YAC transgene rescues craniofacial and neural tube development in PDGFR-alpha knockout mice and uncovers a role for PDGFR-alpha in prenatal lung growth
    • Sun T., Jayatilake D., Afink G., Ataliotis P., Nister M., Richardson W. and Smith H. (2000). A human YAC transgene rescues craniofacial and neural tube development in PDGFR-alpha knockout mice and uncovers a role for PDGFR-alpha in prenatal lung growth. Development 127, 4519-4529.
    • (2000) Development , vol.127 , pp. 4519-4529
    • Sun, T.1    Jayatilake, D.2    Afink, G.3    Ataliotis, P.4    Nister, M.5    Richardson, W.6    Smith, H.7
  • 244
    • 0034617095 scopus 로고    scopus 로고
    • A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription
    • Svensson E., Huggins G., Dardik F., Polk C. and Leiden J. (2000). A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription. J. Biol. Chem. 275, 20762-20769.
    • (2000) J. Biol. Chem. , vol.275 , pp. 20762-20769
    • Svensson, E.1    Huggins, G.2    Dardik, F.3    Polk, C.4    Leiden, J.5
  • 245
  • 246
    • 0021646534 scopus 로고
    • Timing and irreversibility of Mullerian duct inhibition in the embryonic reproductive tract of the human male
    • Taguchi O., Cunha G., Lawrence W. and Robboy S. (1984). Timing and irreversibility of Mullerian duct inhibition in the embryonic reproductive tract of the human male. Dev. Biol. 106, 394-398.
    • (1984) Dev. Biol. , vol.106 , pp. 394-398
    • Taguchi, O.1    Cunha, G.2    Lawrence, W.3    Robboy, S.4
  • 247
    • 53149147384 scopus 로고    scopus 로고
    • Ectopic expression of mouse Sry interferes with Wnt/beta-catenin signaling in mouse embryonal carcinoma cell lines
    • Tamashiro D.A.A., Alarcón V.B. and Marikawa Y. (2008). Ectopic expression of mouse Sry interferes with Wnt/beta-catenin signaling in mouse embryonal carcinoma cell lines. Biochim. Biophys. Acta 1780, 1395-1402.
    • (2008) Biochim. Biophys. Acta , vol.1780 , pp. 1395-1402
    • Tamashiro, D.A.A.1    Alarcón, V.B.2    Marikawa, Y.3
  • 248
    • 0028000696 scopus 로고
    • Diaphragmatic herniae and translocations involving 8q22 in two patients
    • Temple I., Barber J., James R. and Burge D. (1994). Diaphragmatic herniae and translocations involving 8q22 in two patients. J. Med. Genet. 31, 735-737.
    • (1994) J. Med. Genet. , vol.31 , pp. 735-737
    • Temple, I.1    Barber, J.2    James, R.3    Burge, D.4
  • 249
    • 0034705318 scopus 로고    scopus 로고
    • FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
    • Tevosian S., Deconinck A., Tanaka M., Schinke M., Litovsky S., Izumo S., Fujiwara Y. and Orkin S. (2000). FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell 101, 729-739.
    • (2000) Cell , vol.101 , pp. 729-739
    • Tevosian, S.1    Deconinck, A.2    Tanaka, M.3    Schinke, M.4    Litovsky, S.5    Izumo, S.6    Fujiwara, Y.7    Orkin, S.8
  • 250
    • 0036796863 scopus 로고    scopus 로고
    • Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2
    • Tevosian S., Albrecht K., Crispino J., Fujiwara Y., Eicher E. and Orkin S. (2002). Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development 129, 4627-4634.
    • (2002) Development , vol.129 , pp. 4627-4634
    • Tevosian, S.1    Albrecht, K.2    Crispino, J.3    Fujiwara, Y.4    Eicher, E.5    Orkin, S.6
  • 251
    • 0036377459 scopus 로고    scopus 로고
    • Cellular and molecular pathways regulating mammalian sex determination
    • Tilmann C. and Capel B. (2002). Cellular and molecular pathways regulating mammalian sex determination. Recent Prog. Horm. Res. 57, 1-18.
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 1-18
    • Tilmann, C.1    Capel, B.2
  • 254
    • 0033305667 scopus 로고    scopus 로고
    • Transcription factor GATA-4 enhances Mullerian inhibiting substance gene transcription through a direct interaction with the nuclear receptor SF-1
    • Tremblay J. and Viger R. (1999). Transcription factor GATA-4 enhances Mullerian inhibiting substance gene transcription through a direct interaction with the nuclear receptor SF-1. Mol. Endocrinol. 13, 1388-1401.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 1388-1401
    • Tremblay, J.1    Viger, R.2
  • 255
    • 0035076553 scopus 로고    scopus 로고
    • Nuclear receptor Dax-1 represses the transcriptional cooperation between GATA-4 and SF-1 in Sertoli cells
    • Tremblay J. and Viger R. (2001). Nuclear receptor Dax-1 represses the transcriptional cooperation between GATA-4 and SF-1 in Sertoli cells. Biol. Reprod. 64, 1191-1199.
    • (2001) Biol. Reprod. , vol.64 , pp. 1191-1199
    • Tremblay, J.1    Viger, R.2
  • 256
    • 0142180064 scopus 로고    scopus 로고
    • A mutated form of steroidogenic factor 1 (SF-1 G35E) that causes sex reversal in humans fails to synergize with transcription factor GATA-4
    • Tremblay J. and Viger R. (2003). A mutated form of steroidogenic factor 1 (SF-1 G35E) that causes sex reversal in humans fails to synergize with transcription factor GATA-4. J. Biol. Chem. 278, 42637-42642.
    • (2003) J. Biol. Chem. , vol.278 , pp. 42637-42642
    • Tremblay, J.1    Viger, R.2
  • 257
    • 0034824467 scopus 로고    scopus 로고
    • Modulation of endogenous GATA-4 activity reveals its dual contribution to Mullerian inhibiting substance gene transcription in Sertoli cells
    • Tremblay J., Robert N. and Viger R. (2001). Modulation of endogenous GATA-4 activity reveals its dual contribution to Mullerian inhibiting substance gene transcription in Sertoli cells. Mol. Endocrinol. 15, 1636-1650.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1636-1650
    • Tremblay, J.1    Robert, N.2    Viger, R.3
  • 258
    • 0031472234 scopus 로고    scopus 로고
    • FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
    • Tsang A., Visvader J., Turner C., Fujiwara Y., Yu C., Weiss M., Crossley M. and Orkin S. (1997). FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90, 109-119.
    • (1997) Cell , vol.90 , pp. 109-119
    • Tsang, A.1    Visvader, J.2    Turner, C.3    Fujiwara, Y.4    Yu, C.5    Weiss, M.6    Crossley, M.7    Orkin, S.8
  • 260
    • 33745505572 scopus 로고    scopus 로고
    • Foxl2 function in ovarian development
    • Uhlenhaut N.H. and Treier M. (2006). Foxl2 function in ovarian development. Mol. Genet. Metab. 88, 225-234.
    • (2006) Mol. Genet. Metab. , vol.88 , pp. 225-234
    • Uhlenhaut, N.H.1    Treier, M.2
  • 262
    • 0033521967 scopus 로고    scopus 로고
    • Female development in mammals is regulated by Wnt-4 signalling
    • Vainio S., Heikkilä M., Kispert A., Chin N. and McMahon A.P. (1999). Female development in mammals is regulated by Wnt-4 signalling. Nature 397, 405-409.
    • (1999) Nature , vol.397 , pp. 405-409
    • Vainio, S.1    Heikkilä, M.2    Kispert, A.3    Chin, N.4    McMahon, A.P.5
  • 263
  • 266
    • 0031876652 scopus 로고    scopus 로고
    • Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter
    • Viger R., Mertineit C., Trasler J. and Nemer M. (1998). Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter. Development 125, 2665-2675.
    • (1998) Development , vol.125 , pp. 2665-2675
    • Viger, R.1    Mertineit, C.2    Trasler, J.3    Nemer, M.4
  • 267
    • 21644441621 scopus 로고    scopus 로고
    • Role of the GATA family of transcription factors in andrology
    • Viger R., Taniguchi H., Robert N. and Tremblay J. (2004). Role of the GATA family of transcription factors in andrology. J. Androl. 25, 441-452.
    • (2004) J. Androl. , vol.25 , pp. 441-452
    • Viger, R.1    Taniguchi, H.2    Robert, N.3    Tremblay, J.4
  • 268
    • 0023266218 scopus 로고
    • Puri?ed bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to it in vitro
    • Vigier B., Watrin F., Magre S., Tran D. and Josso N. (1987). Puri?ed bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to it in vitro. Development 100, 43-55.
    • (1987) Development , vol.100 , pp. 43-55
    • Vigier, B.1    Watrin, F.2    Magre, S.3    Tran, D.4    Josso, N.5
  • 269
  • 271
    • 0034651236 scopus 로고    scopus 로고
    • Endogenous expression of Mullerian inhibiting substance in early postnatal rat Sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites
    • Watanabe K., Clarke T., Lane A., Wang X. and Donahoe P. (2000). Endogenous expression of Mullerian inhibiting substance in early postnatal rat Sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites. Proc. Natl. Acad. Sci. USA 97, 1624-1629.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1624-1629
    • Watanabe, K.1    Clarke, T.2    Lane, A.3    Wang, X.4    Donahoe, P.5
  • 272
    • 34447526784 scopus 로고    scopus 로고
    • R-spondin1 is a high af?nity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling
    • Wei Q., Yokota C., Semenov M.V., Doble B., Woodgett J. and He X. (2007). R-spondin1 is a high af?nity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. J. Biol. Chem. 282, 15903-15911.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15903-15911
    • Wei, Q.1    Yokota, C.2    Semenov, M.V.3    Doble, B.4    Woodgett, J.5    He, X.6
  • 273
    • 0028883199 scopus 로고
    • GATA transcription factors: Key regulators of hematopoiesis
    • Weiss M. and Orkin S. (1995). GATA transcription factors: key regulators of hematopoiesis. Exp. Hematol. 23, 99-107.
    • (1995) Exp. Hematol. , vol.23 , pp. 99-107
    • Weiss, M.1    Orkin, S.2
  • 274
    • 0242664116 scopus 로고    scopus 로고
    • Sox3 is required for gonadal function, but not sex determination, in males and females
    • Weiss J., Meeks J.J., Hurley L., Raverot G., Frassetto A. and Jameson J.L. (2003). Sox3 is required for gonadal function, but not sex determination, in males and females. Mol. Cell. Biol. 23, 8084-8091.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8084-8091
    • Weiss, J.1    Meeks, J.J.2    Hurley, L.3    Raverot, G.4    Frassetto, A.5    Jameson, J.L.6
  • 275
    • 0029024472 scopus 로고
    • Assignment of the transcription factor GATA4 gene to human chromosome 8 and mouse chromosome 14: Gata4 is a candidate gene for Ds (disorganization)
    • White R., Dowler L., Pasztor L., Gatson L., Adkison L., Angeloni S. and Wilson D. (1995). Assignment of the transcription factor GATA4 gene to human chromosome 8 and mouse chromosome 14: Gata4 is a candidate gene for Ds (disorganization). Genomics 27, 20-26.
    • (1995) Genomics , vol.27 , pp. 20-26
    • White, R.1    Dowler, L.2    Pasztor, L.3    Gatson, L.4    Adkison, L.5    Angeloni, S.6    Wilson, D.7
  • 276
    • 34248150313 scopus 로고    scopus 로고
    • WNT4 and RSPO1 are not involved in a case of male-to-female sex reversal with partial duplication of 1p
    • Wieacker P. and Volleth M. (2007). WNT4 and RSPO1 are not involved in a case of male-to-female sex reversal with partial duplication of 1p. Sex. Dev. 1, 111-113.
    • (2007) Sex. Dev. , vol.1 , pp. 111-113
    • Wieacker, P.1    Volleth, M.2
  • 277
    • 0037099299 scopus 로고    scopus 로고
    • The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1
    • Wilhelm D. and Englert C. (2002). The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1. Genes Dev. 16, 1839-1851.
    • (2002) Genes Dev. , vol.16 , pp. 1839-1851
    • Wilhelm, D.1    Englert, C.2
  • 278
    • 27744559963 scopus 로고    scopus 로고
    • Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination
    • Wilhelm D., Martinson F., Bradford S., Wilson M.J., Combes A.N., Beverdam. A., Bowles J., Mizusaki H. and Koopman P. (2005). Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev. Biol. 287, 111-124.
    • (2005) Dev. Biol. , vol.287 , pp. 111-124
    • Wilhelm, D.1    Martinson, F.2    Bradford, S.3    Wilson, M.J.4    Combes, A.N.5    Beverdam, A.6    Bowles, J.7    Mizusaki, H.8    Koopman, P.9
  • 279
    • 34249854973 scopus 로고    scopus 로고
    • SOX9 regulates prostaglandin-D-synthase gene transcription in vivo to ensure testis development
    • Wilhelm D., Hiramatsu R., Mizusaki H., Widjaja L., Combes A.N., Kanai Y. and Koopman P. (2007). SOX9 regulates prostaglandin-D-synthase gene transcription in vivo to ensure testis development. J. Biol. Chem. 282, 10553-10560.
    • (2007) J. Biol. Chem. , vol.282 , pp. 10553-10560
    • Wilhelm, D.1    Hiramatsu, R.2    Mizusaki, H.3    Widjaja, L.4    Combes, A.N.5    Kanai, Y.6    Koopman, P.7
  • 281
    • 14044260735 scopus 로고    scopus 로고
    • The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
    • Wilson M.J., Jeyasuria P., Parker K.L. and Koopman P. (2005). The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J. Biol. Chem. 280, 5917-5923.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5917-5923
    • Wilson, M.J.1    Jeyasuria, P.2    Parker, K.L.3    Koopman, P.4
  • 284
    • 33645957960 scopus 로고    scopus 로고
    • Sexually dimorphic regulation of inhibin beta B in establishing gonadal vasculature in mice
    • Yao H.H., Aardema J. and Holthusen K. (2006). Sexually dimorphic regulation of inhibin beta B in establishing gonadal vasculature in mice. Biol. Reprod. 74, 978-983.
    • (2006) Biol. Reprod. , vol.74 , pp. 978-983
    • Yao, H.H.1    Aardema, J.2    Holthusen, K.3
  • 286
    • 0035064929 scopus 로고    scopus 로고
    • Transcriptional regulation of the androgen signaling pathway by the Wilms' tumor suppressor gene WT1
    • Zaia A., Fraizer G., Piantanelli L. and Saunders G. (2001). Transcriptional regulation of the androgen signaling pathway by the Wilms' tumor suppressor gene WT1. Anticancer Res. 21, 1-10.
    • (2001) Anticancer Res. , vol.21 , pp. 1-10
    • Zaia, A.1    Fraizer, G.2    Piantanelli, L.3    Saunders, G.4
  • 288
    • 0035293669 scopus 로고    scopus 로고
    • Establishing sexual dimorphism: Conservation amidst diversity?
    • Zarkower D. (2001). Establishing sexual dimorphism: conservation amidst diversity? Nat. Rev. Genet. 2, 175-185.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 175-185
    • Zarkower, D.1


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