Comparative localization of Dax-1 and Ad4BP/SF-1 during development of the hypothalamic-pituitary-gonadal axis suggests their closely related and distinct functions

Developmental Dynamics

Volumn 220, Issue 4, 2001, Pages 363-376

  Ikeda, Yayoi ^a   Takeda, Yoshie ^b,c   Shikayama, Tatsuji ^b,c   Mukai, Tokuo ^b,c,d   Hisano, Setsuji ^a   Morohashi, Ken Ichirou ^a,b,c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Ad4BP SF 1; Dax 1; Gonadal development; Hypothalamic pituitary gonadal axis; Immunohistochemistry; Reproductive system; Sex differentiation

Indexed keywords

CELL NUCLEUS RECEPTOR; NUCLEAR RECEPTOR DAX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; GENE MUTATION; GONAD DEVELOPMENT; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MOUSE; NONHUMAN; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; SEX DIFFERENTIATION; ZONA INCERTA;

ANIMALS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FEMALE; FUSHI TARAZU TRANSCRIPTION FACTORS; GONADS; HOMEODOMAIN PROTEINS; HYPOTHALAMUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LEYDIG CELLS; MALE; MICE; OVARY; PITUITARY GLAND; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERTOLI CELLS; SEX FACTORS; TESTIS; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 0035079932     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.1116     Document Type: Article

References (34)

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4. Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
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10. The nuclear receptor steroidogenic factor 1 is essential for the formation of ventromedial hypothalamic nucleus
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12. The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis
13. DAX-1 inhibits SF-1-mediated trans-activation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita
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