Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development

Developmental Biology

Volumn 215, Issue 2, 1999, Pages 208-220

  Raymond, Christopher S ^a   Kettlewell, Jae R ^a   Hirsch, Betsy ^b   Bardwell, Vivian J ^a   Zarkower, David ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

DM domain; Dmrt1; Doublesex; Mab 3; Sex determination

Indexed keywords

REGULATOR PROTEIN;

ARTICLE; BIRD; CAENORHABDITIS ELEGANS; CHICKEN; DNA BINDING; DROSOPHILA; EMBRYONIC STRUCTURES; GENE EXPRESSION REGULATION; GONAD DEVELOPMENT; KARYOTYPING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATOR GENE; SEMINIFEROUS TUBULE; SERTOLI CELL; SEX DIFFERENTIATION; SEXUAL DEVELOPMENT; TESTIS; TESTIS DEVELOPMENT; VERTEBRATE;

AVES; CAENORHABDITIS ELEGANS; GALLUS GALLUS; MAMMALIA; MURINAE; STAPHYLOCOCCUS PHAGE 3A; VERTEBRATA; WOLFFIA;

EID: 0033571276     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9461     Document Type: Article

References (49)

1. Aguinaldo A. M., Turbeville J. M., Linford L. S., Rivera M. C., Garey J. R., Raff R. A., Lake J. A. Evidence for a clade of nematodes, arthropods and other moulting animals. Nature. 387:1997;489-493.
2. Anderson R., Fassler R., Georges-Labouesse E., Hynes R. O., Bader B. L., Kreidberg J. A., Schaible K., Heasman J., Wylie C. Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads. Development. 126:1999;1655-1664.
3. Baker B. S., Ridge K. A. Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster. Genetics. 94:1980;383-423.
4. Baverstock P. R., Adams M., Polkinghorne R. W., Gelder M. A sex-linked enzyme in birds - Z-chromosome conservation but no dosage compensation. Nature. 296:1982;763-766.
5. Bennett C. P., Docherty Z., Robb S. A., Ramani P., Hawkins J. R., Grant D. Deletion 9p and sex reversal. J. Med. Genet. 30:1993;518-520.
6. Bogan J. S., Page D. C. Ovary? Testis? - A mammalian dilemma. Cell. 76:1994;603-607.
7. Bownes M. The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster. BioEssays. 16:1994;745-752.
8. Buehr M., McLaren A., Bartley A., Darling S. Proliferation and migration of primordial germ cells in We/We mouse embryos. Dev. Dyn. 198:1993;182-189.
9. Burtis K. C., Baker B. S. Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell. 56:1989;997-1010.
10. Cline T. W., Meyer B. J. Vive la difference: Males vs females in flies vs worms. Annu. Rev. Genet. 30:1996;637-702.
11. Coucouvanis E., Martin G. R. BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. Development. 126:1999;535-546.
12. de Bono M., Hodgkin J. Evolution of sex determination in Caenorhabditis: Unusually high divergence of tra-1 and its functional consequences. Genetics. 144:1996;587-595.
13. Erdman S. E., Burtis K. C. The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. EMBO J. 12:1993;527-535.
14. Erdman S. E., Chen H.-J., Burtis K. C. Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila Doublesex proteins. Genetics. 144:1996;1639-1652.
15. Flejter W. L., Fergestad J., Gorski J., Varvill T., Chandrasekharappa S. A gene involved in XY sex reversal is located on chromosome 9, distal to marker D9S1779. Am. J. Hum. Genet. 63:1998;794-802.
16. Griffiths R., Double M. C., Orr K., Dawson R. J. A DNA test to sex most birds. Mol. Ecol. 7:1998;1071-1075.
17. Guioli S., Schmitt K., Critcher R., Bouzyk M., Spurr N. K., Ogata T., Hoo J. J., Pinsky L., Gimelli G., Pasztor L., Goodfellow P. N. Molecular analysis of 9p deletions associated with XY sex reversal: Refining the localization of a sex-determining gene to the tip of the chromosome. Am. J. Hum. Genet. 63:1998;905-908.
18. Hacker A., Capel B., Goodfellow P., Lovell-Badge R. Expression of Sry, the mouse sex determining gene. Development. 121:1995;1603-1614.
19. Hamburger V., Hamilton H. L. A series of normal stages in the development of the chick embryo. J. Morphol. 88:1951;49-92.
20. Henrique D., Adam J., Myat A., Chitnis A., Lewis J., Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature. 375:1995;787-790.
21. Jost A. Studies on sex differentiation in mammals. Recent Prog. Horm. Res. 8:1953;379-418.
22. Kent J., Wheatley S. C., Andrews J. E., Sinclair A. H., Koopman P. A male-specific role for SOX9 in vertebrate sex determination. Development. 122:1996;2813-2822.
23. Kreidberg J. A., Sariola H., Loring J. M., Maeda M., Pelletier J., Housman D., Jaenisch R. WT-1 is required for early kidney development. Cell. 74:1993;679-691.
24. Kuwabara P. E. Interspecies comparison reveals evolution of control regions in the nematode sex-determining gene tra-2. Genetics. 144:1996;597-607.
25. Luo X., Ikeda Y., Parker K. L. A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell. 77:1994;481-490.
26. Marin I., Baker B. S. The evolutionary dynamics of sex determination. Science. 281:1998;1990-1994.
27. Meng A., Moore B., Tang H., Yuan B., Lin S. A Drosophila doublesex-related gene, terra, is involved in somitogenesis in vertebrates. Development. 126:1999;1259-1268.
28. Morais da Silva S., Hacker A., Harley V., Goodfellow P., Swain A., Lovell-Badge R. Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat. Genet. 14:1996;62-68.
29. Nachtigal M. W., Hirokawa Y., Enyeart-VanHouten D. L., Flanagan J. N., Hammer G. D., Ingraham H. A. Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell. 93:1998;445-454.
30. Nanda I., Shan Z., Schartl M., Burt D. W., Koehler M., Nothwang H., Grutzner F., Paton I. R., Windsor D., Dunn I., Engel W., Staeheli P., Mizuno S., Haaf T., Schmid M. 300 million years of conserved synteny between chicken Z and human chromosome 9. Nat. Genet. 21:1999;258-259.
31. Oreal E., Pieau C., Mattei M. G., Josso N., Picard J. Y., Carre-Eusebe D., Magre S. Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expression. Dev. Dyn. 212:1998;522-532.
32. Raymond C. S., Parker E. D., Kettlewell J. R., Brown L. G., Page D. C., Kusz K., Jaruzelska J., Reinberg Y., Flejter W. L., Bardwell V., Hirsch B., Zarkower D. A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators. Hum. Mol. Genet. 8:1999;989-996.
33. Raymond C. S., Shamu C. E., Shen M. M., Seifert K. J., Hirsch B., Hodgkin J., Zarkower D. Evidence for evolutionary conservation of sex-determining genes. Nature. 391:1998;691-695.
34. Schafer A. J., Goodfellow P. N. Sex determination in humans. BioEssays. 18:1996;955-963.
35. Schmid M., Enderle E., Schindler D., Schempp W. Chromosome banding and DNA replication patterns in bird karyotypes. Cytogenet. Cell Genet. 52:1989;139-146.
36. Shen M. M., Hodgkin J. a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegans. Cell. 54:1988;1019-1031.
37. Sinclair A. H., Berta P., Palmer M. S., Hawkins J. R., Griffiths B. L., Smith M. J., Foster J. W., Frischauf A. M., Lovell B. R., Goodfellow P. N. A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature. 346:1990;240-244.
38. Smith C. A., Smith M. J., Sinclair A. H. Gene expression during gonadogenesis in the chicken embryo. Gene. 234:1999;395-402.
39. Swain A., Narvaez V., Burgoyne P., Camerino G., Lovell-Badge R. Dax1 antagonizes Sry action in mammalian sex determination. Nature. 391:1998;761-767.
40. Trask B. Fluorescence in situ hybridization. Birren B., Green E., Hieter P., Myers R. Genome Analysis: A Laboratory Manual. 1997;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
41. Vainio S., Heikkila M., Kispert A., Chin N., McMahon A. P. Female development in mammals is regulated by Wnt-4 signalling. Nature. 397:1999;405-409.
42. Valentine J. W., Jablonski D., Erwin D. H. Fossils, molecules and embryos: New perspectives on the cambrian explosion. Development. 126:1999;851-859.
43. Veitia R., Nunes M., Brauner R., Doco-Fenzy M., Joanny-Flinois O., Jaubert F., Lortat-Jacob S., Fellous M., McElreavey K. Deletions of distal 9p associated with 46,XY male to female sex reversal: Definition of the breakpoints at 9p23.3-p24.1. Genomics. 41:1997;271-274.
44. Veitia R. A., Nunes M., Quintana-Murci L., Rappaport R., Thibaud E., Jaubert F., Fellous M., McElreavey K., Goncalves J., Silva M., Rodrigues J. C., Caspurro M., Boieiro F., Marques R., Lavinha J. Swyer syndrome and 46,XY partial gonadal dysgenesis associated with 9p deletions in the absence of monosomy-9p syndrome. Am. J. Hum. Genet. 63:1998;901-905.
45. Wagner T., Wirth J., Meyer J., Zabel B., Held M., Zimmer J., Pasantes J., Bricarelli F. D., Keutel J., Hustert E. Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell. 79:1994;1111-1120.
46. Whitfield L. S., Lovell-Badge R., Goodfellow P. N. Rapid sequence evolution of the mammalian sex-determining gene SRY. Nature. 364:1993;713-715.
47. Wilkie A. O., Campbell F. M., Daubeney P., Grant D. B., Daniels R. J., Mullarkey M., Affara N. A., Fitchett M., Huson S. M. Complete and partial XY sex reversal associated with terminal deletion of 10q: Report of 2 cases and literature review. Am. J. Med. Genet. 46:1993;597-600.
48. Yi W., Zarkower D. Similarity of DNA binding and transcriptional regulation by Caenorhabditis elegans MAB-3 and Drosophila melanogaster DSX suggests conservation of sex determining mechanisms. Development. 126:1999;873-881.
49. Yu R. N., Ito M., Saunders T. L., Camper S. A., Jameson J. L. Role of Ahch in gonadal development and gametogenesis. Nat. Genet. 20:1998;353-357.