메뉴 건너뛰기




Volumn 10, Issue 20, 1996, Pages 2577-2587

Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation

Author keywords

anti Mullerian hormone; testis; TGF gene family; tumorigenesis

Indexed keywords

MUELLERIAN INHIBITING FACTOR; TRANSFORMING GROWTH FACTOR BETA; INHIBIN; LIGAND; MULLERIAN INHIBITING SUBSTANCE RECEPTOR; MULLERIAN-INHIBITING SUBSTANCE RECEPTOR; RECEPTOR;

EID: 0029658831     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.20.2577     Document Type: Article
Times cited : (313)

References (55)
  • 1
    • 0026527384 scopus 로고
    • Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
    • Attisano, L., J.L. Wrana, S. Cheifetz, and J. Massagué. 1992. Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors. Cell 68: 97-108.
    • (1992) Cell , vol.68 , pp. 97-108
    • Attisano, L.1    Wrana, J.L.2    Cheifetz, S.3    Massagué, J.4
  • 2
    • 0027525105 scopus 로고
    • Identification of human activin and TGFβ type I receptors that form heterodimeric kinase complexes with type II receptors
    • Attisano, L., J. Cárcamo, F. Ventura, F.M.B. Weis, J. Massagué, and J.L. Wrana. 1993. Identification of human activin and TGFβ type I receptors that form heterodimeric kinase complexes with type II receptors. Cell 75: 671-680.
    • (1993) Cell , vol.75 , pp. 671-680
    • Attisano, L.1    Cárcamo, J.2    Ventura, F.3    Weis, F.M.B.4    Massagué, J.5    Wrana, J.L.6
  • 4
    • 0028972865 scopus 로고
    • Anti-Müllerian hormone and anti-Müllerian hormone type II receptor messenger ribonucleic acid expression during postnatal testis development and in the adult testis of the rat
    • Baarends, W.M., J.W. Hoogerbrugghe, M. Post, J.A. Visser, D.G. de Rooij, M. Parvinen, A.P.N. Themmen, and J.A. Grootegoed. 1995a. Anti-Müllerian hormone and anti-Müllerian hormone type II receptor messenger ribonucleic acid expression during postnatal testis development and in the adult testis of the rat. Endocrinology 136: 5614-5622.
    • (1995) Endocrinology , vol.136 , pp. 5614-5622
    • Baarends, W.M.1    Hoogerbrugghe, J.W.2    Post, M.3    Visser, J.A.4    De Rooij, D.G.5    Parvinen, M.6    Themmen, A.P.N.7    Grootegoed, J.A.8
  • 5
    • 0028973297 scopus 로고
    • Anti-Mülerian hormone and anti-Müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth
    • Baarends, W.M., J.T.J. Uilenbroek, P. Kramer, J.W. Hoogerbrugghe, J.P. de Winter, B. Karels, L.G. Wilming, E.C.M. van Leeuwen, A.P.N. Themmen, and J.A. Grootegoed. 1995b. Anti-Mülerian hormone and anti-Müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth. Endocrinology 136: 4951-4962.
    • (1995) Endocrinology , vol.136 , pp. 4951-4962
    • Baarends, W.M.1    Uilenbroek, J.T.J.2    Kramer, P.3    Hoogerbrugghe, J.W.4    De Winter, J.P.5    Karels, B.6    Wilming, L.G.7    Van Leeuwen, E.C.M.8    Themmen, A.P.N.9    Grootegoed, J.A.10
  • 6
    • 0025312139 scopus 로고
    • Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance
    • Behringer, R.R., R.L. Cate, G.J. Froelick, R.D. Palmiter, and R.L. Brinster. 1990. Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance. Nature 345: 167-170.
    • (1990) Nature , vol.345 , pp. 167-170
    • Behringer, R.R.1    Cate, R.L.2    Froelick, G.J.3    Palmiter, R.D.4    Brinster, R.L.5
  • 7
    • 0028172159 scopus 로고
    • Müllerian-inhibiting substance function during mammalian sexual development
    • Behringer, R.R., M.J. Finegold, and R.L. Cate. 1994. Müllerian- inhibiting substance function during mammalian sexual development. Cell 79: 415-425.
    • (1994) Cell , vol.79 , pp. 415-425
    • Behringer, R.R.1    Finegold, M.J.2    Cate, R.L.3
  • 8
  • 9
    • 0027008377 scopus 로고
    • Variants of the anti-Müllerian hormone gene in a compound heterozygotes with the persistent Müllerian duct syndrome and his family
    • Carré-Eusèbe, D., S. Imbeaud, M. Harbison, M.I. New, N. Josso, and J.-Y. Picard. 1992. Variants of the anti-Müllerian hormone gene in a compound heterozygotes with the persistent Müllerian duct syndrome and his family. Hum. Genet. 90: 389-394.
    • (1992) Hum. Genet. , vol.90 , pp. 389-394
    • Carré-Eusèbe, D.1    Imbeaud, S.2    Harbison, M.3    New, M.I.4    Josso, N.5    Picard, J.-Y.6
  • 10
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction
    • Chomczynski, P. and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 13
    • 0027219671 scopus 로고
    • Cloning of a type I TGFβ receptor and its effect on TGFβ binding to the type II receptor
    • Ebner, R., R.-H. Chen, L. Shum, S. Lawler, T.F. Zioncheck, A. Lee, A.R. Lopez, and R. Derynck. 1993. Cloning of a type I TGFβ receptor and its effect on TGFβ binding to the type II receptor. Science 260: 1344-1348.
    • (1993) Science , vol.260 , pp. 1344-1348
    • Ebner, R.1    Chen, R.-H.2    Shum, L.3    Lawler, S.4    Zioncheck, T.F.5    Lee, A.6    Lopez, A.R.7    Derynck, R.8
  • 14
    • 0027332995 scopus 로고
    • Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGF beta type II receptor
    • Franzén, P. P. ten Dijke, H. Ichijo, H. Yamshita, P. Schul, C.-H. Heldin, and K. Miyazono. 1993. Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGF beta type II receptor. Cell 75: 681-692.
    • (1993) Cell , vol.75 , pp. 681-692
    • Franzén1    Ten Dijke, P.P.2    Ichijo, H.3    Yamshita, H.4    Schul, P.5    Heldin, C.-H.6    Miyazono, K.7
  • 15
    • 0028985296 scopus 로고
    • The GS domain of the transforming growth factor-beta type 1 receptor is important in signal transduction
    • Franzén, P., C.-H. Heldin, and K. Miyazono. 1995. The GS domain of the transforming growth factor-beta type 1 receptor is important in signal transduction. Biochem. Biophys. Res. Comm. 207: 682-689.
    • (1995) Biochem. Biophys. Res. Comm. , vol.207 , pp. 682-689
    • Franzén, P.1    Heldin, C.-H.2    Miyazono, K.3
  • 17
  • 18
    • 0027240959 scopus 로고
    • Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth factor-beta type II receptor family
    • He, W.W., M.L. Gustafson, S. Hirobe, and P.K. Donahoe. 1993. Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth factor-beta type II receptor family. Dev. Dyn. 196: 133-142.
    • (1993) Dev. Dyn. , vol.196 , pp. 133-142
    • He, W.W.1    Gustafson, M.L.2    Hirobe, S.3    Donahoe, P.K.4
  • 19
    • 0028118823 scopus 로고
    • Molecular genetics of the persistent Müllerian duct syndrome: A study of 19 families
    • Imbeaud, S., D. Carreàbe, R. Rey, C. Belville, N. Josso, and J.-Y. Picard. 1994. Molecular genetics of the persistent Müllerian duct syndrome: A study of 19 families. Hum. Mol. Genet. 3: 125-131.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 125-131
    • Imbeaud, S.1    Carreàbe, D.2    Rey, R.3    Belville, C.4    Josso, N.5    Picard, J.-Y.6
  • 21
    • 0029811588 scopus 로고    scopus 로고
    • A 27 base-pair deletion of the anti-Müllerian type II receptor gene is the most common cause of the persistent Müllerian duct syndrome
    • in press
    • Imbeaud, S., C. Belville, L. Messika-Zeitoin, R. Rey, N. di Clemente, N. Josso, and J.-Y. Picard. 1996. A 27 base-pair deletion of the anti-Müllerian type II receptor gene is the most common cause of the persistent Müllerian duct syndrome. Hum. Mol. Genet. (in press).
    • (1996) Hum. Mol. Genet.
    • Imbeaud, S.1    Belville, C.2    Messika-Zeitoin, L.3    Rey, R.4    Di Clemente, N.5    Josso, N.6    Picard, J.-Y.7
  • 23
    • 0000009634 scopus 로고
    • Problems of fetal endocrinology: The gonadal and hypophyseal hormones
    • Jost, A. 1953. Problems of fetal endocrinology: The gonadal and hypophyseal hormones. Recent Prog. Horm. Res. 8: 379-418.
    • (1953) Recent Prog. Horm. Res. , vol.8 , pp. 379-418
    • Jost, A.1
  • 25
    • 0028180315 scopus 로고
    • The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley, D.M. 1994. The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes & Dev. 8: 133-146.
    • (1994) Genes & Dev. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 26
    • 0025920616 scopus 로고
    • Anti-Müllerian hormone Bruxelles: A non-sense mutation in the last exon of the anti Müllerian hormone gene associated with the persistent Müllerian duct syndrome in three brothers
    • Knebelmann, B., L. Boussin, D. Guerrier, L. Legeai, A. Kahn, N. Josso, and J.-Y. Picard. 1991. Anti-Müllerian hormone Bruxelles: A non-sense mutation in the last exon of the anti Müllerian hormone gene associated with the persistent Müllerian duct syndrome in three brothers. Proc. Natl. Acad. Sci. 88: 3767-3771.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 3767-3771
    • Knebelmann, B.1    Boussin, L.2    Guerrier, D.3    Legeai, L.4    Kahn, A.5    Josso, N.6    Picard, J.-Y.7
  • 28
    • 0028797535 scopus 로고
    • Ontogeny of reproductive abnormalities induced by deregulation of anti-Müllerian hormone expression in transgenic mice
    • Lyet, L., F. Louis, M.G. Forest, N. Josso, R.R. Behringer, and B. Vigier. 1995. Ontogeny of reproductive abnormalities induced by deregulation of anti-Müllerian hormone expression in transgenic mice. Biol. Reprod. 52: 444-454.
    • (1995) Biol. Reprod. , vol.52 , pp. 444-454
    • Lyet, L.1    Louis, F.2    Forest, M.G.3    Josso, N.4    Behringer, R.R.5    Vigier, B.6
  • 29
    • 0025188130 scopus 로고
    • The Wnt-1 (int-1) protooncogene is required for development of a large region of the mouse brain
    • McMahon, A.P. and A. Bradley. 1990. The Wnt-1 (int-1) protooncogene is required for development of a large region of the mouse brain. Cell 62: 1073-1085.
    • (1990) Cell , vol.62 , pp. 1073-1085
    • McMahon, A.P.1    Bradley, A.2
  • 30
    • 0024296027 scopus 로고
    • Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to nonselectable genes
    • Mansour, S.L., K.R. Thomas, and M.R. Capecchi. 1988. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to nonselectable genes. Nature 336: 348-352.
    • (1988) Nature , vol.336 , pp. 348-352
    • Mansour, S.L.1    Thomas, K.R.2    Capecchi, M.R.3
  • 31
  • 32
    • 0027254208 scopus 로고
    • A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, or bone morphogenetic factor
    • Matsuzaki, K., J. Xu, F. Wang, W.L. McKeehan, L. Krummen, and M. Kan. 1993. A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, or bone morphogenetic factor. J. Biol. Chem. 268: 12718-12723.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12718-12723
    • Matsuzaki, K.1    Xu, J.2    Wang, F.3    McKeehan, W.L.4    Krummen, L.5    Kan, M.6
  • 33
    • 0026621796 scopus 로고
    • α-Inhibin is a tumour-suppressor gene with gonadal specificity in mice
    • Matzuk, M.M., M.J. Finegold, J.-G.J. Su, A.J.W. Hsueh, and A. Bradley. 1992. α-Inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360: 313-319.
    • (1992) Nature , vol.360 , pp. 313-319
    • Matzuk, M.M.1    Finegold, M.J.2    Su, J.-G.J.3    Hsueh, A.J.W.4    Bradley, A.5
  • 34
    • 0029144102 scopus 로고
    • Synergistic effects of inhibins and Müllerian-inhibiting substance on testicular tumorigenesis
    • Matzuk, M.M., M.J. Finegold, Y. Mishina, A. Bradley, and R.R. Behringer. 1995a. Synergistic effects of inhibins and Müllerian-inhibiting substance on testicular tumorigenesis. Mol. Endocrin. 9: 1337-1345.
    • (1995) Mol. Endocrin. , vol.9 , pp. 1337-1345
    • Matzuk, M.M.1    Finegold, M.J.2    Mishina, Y.3    Bradley, A.4    Behringer, R.R.5
  • 35
    • 0028929864 scopus 로고
    • Different phenotypes for mice deficient in either activins or activin receptor type II
    • Matzuk, M.M., T.R. Kumar, and A. Bradley. 1995b. Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 374: 356-360.
    • (1995) Nature , vol.374 , pp. 356-360
    • Matzuk, M.M.1    Kumar, T.R.2    Bradley, A.3
  • 37
    • 0024854249 scopus 로고
    • Müllerian inhibiting substance is present in testes of dogs with persistent Müllerian duct syndrome
    • Meyers-Wallen, V.N., P.K. Donahoe, S. Ueno, T.F. Manganaro, and D.F. Patterson. 1989. Müllerian inhibiting substance is present in testes of dogs with persistent Müllerian duct syndrome. Biol. Reprod. 41: 881-888.
    • (1989) Biol. Reprod. , vol.41 , pp. 881-888
    • Meyers-Wallen, V.N.1    Donahoe, P.K.2    Ueno, S.3    Manganaro, T.F.4    Patterson, D.F.5
  • 38
    • 0028796635 scopus 로고
    • Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
    • Mishina, Y., A. Suzuki, N. Ueno, and R.R. Behringer. 1995. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes & Dev. 206: 310-317.
    • (1995) Genes & Dev. , vol.206 , pp. 310-317
    • Mishina, Y.1    Suzuki, A.2    Ueno, N.3    Behringer, R.R.4
  • 39
    • 0025950803 scopus 로고
    • Expression of the mouse anti-Müllerian hormone gene suggests a role in both male and female sexual differentiation
    • Münsterberg, A., and R. Lovell-Badge. 1991 Expression of the mouse anti-Müllerian hormone gene suggests a role in both male and female sexual differentiation. Development 113: 613-624.
    • (1991) Development , vol.113 , pp. 613-624
    • Münsterberg, A.1    Lovell-Badge, R.2
  • 41
    • 0017111158 scopus 로고
    • Familial persistent Müllerian duct syndrome
    • Sloan, W.R. and P.C. Walsh. 1976. Familial persistent Müllerian duct syndrome. J. Urol. 115: 459-461.
    • (1976) J. Urol. , vol.115 , pp. 459-461
    • Sloan, W.R.1    Walsh, P.C.2
  • 42
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
    • Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64: 693-702.
    • (1991) Cell , vol.64 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4
  • 43
    • 0028176586 scopus 로고
    • A mouse TGF-β type I receptor that requires type II receptor for ligand binding
    • Suzuki, A., N. Shioda, T. Maeda, M. Tada, and N. Ueno. 1994. A mouse TGF-β type I receptor that requires type II receptor for ligand binding. Biochem. Biophys. Res. Comm. 298: 1063-1069.
    • (1994) Biochem. Biophys. Res. Comm. , vol.298 , pp. 1063-1069
    • Suzuki, A.1    Shioda, N.2    Maeda, T.3    Tada, M.4    Ueno, N.5
  • 45
    • 0027328191 scopus 로고
    • Activin receptor-like kinases: A novel subclass of cell-surface receptors with predicted serine/threonine kinase activity
    • ten Dijke, P., H. Ichijo, P. Franzén, P. Schulz, J. Saras, H. Toyoshima, C.-H. Heldin, and K. Miyazono. 1993. Activin receptor-like kinases: A novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene 8: 2879-2887.
    • (1993) Oncogene , vol.8 , pp. 2879-2887
    • Ten Dijke, P.1    Ichijo, H.2    Franzén, P.3    Schulz, P.4    Saras, J.5    Toyoshima, H.6    Heldin, C.-H.7    Miyazono, K.8
  • 47
    • 0000775642 scopus 로고
    • The inhibin/activin family of hormones and growth factors
    • ed. M.B. Sporn and A.B. Roberts, Springer-Verlag, Germany
    • Vale, W., A. Hsueh, C. Rivier, and J. Yu. 1990. The inhibin/activin family of hormones and growth factors. In Peptide growth factors and their receptors II (ed. M.B. Sporn and A.B. Roberts), pp. 211-248. Springer-Verlag, Germany.
    • (1990) Peptide Growth Factors and Their Receptors II , vol.2 , pp. 211-248
    • Vale, W.1    Hsueh, A.2    Rivier, C.3    Yu, J.4
  • 48
    • 0028176755 scopus 로고
    • Activin/inhibin βB subunit gene disruption leads to defects in eyelid development and female reproduction
    • Vassalli, A., M.M. Matzuk, H.A.R. Gardner, K.-F. Lee, and R. Jaenisch. 1994. Activin/inhibin βB subunit gene disruption leads to defects in eyelid development and female reproduction. Genes & Dev. 8: 414-427.
    • (1994) Genes & Dev. , vol.8 , pp. 414-427
    • Vassalli, A.1    Matzuk, M.M.2    Gardner, H.A.R.3    Lee, K.-F.4    Jaenisch, R.5
  • 49
    • 0021288021 scopus 로고
    • Production of anti-Müllerian hormone: Another homology between Sertoli and granulosa cells
    • Vigier, B., J.-Y. Picard, D. Tran, L. Legai, and N. Josso. 1984. Production of anti-Müllerian hormone: Another homology between Sertoli and granulosa cells. Endocrinology 114: 1315-1320.
    • (1984) Endocrinology , vol.114 , pp. 1315-1320
    • Vigier, B.1    Picard, J.-Y.2    Tran, D.3    Legai, L.4    Josso, N.5
  • 50
    • 0023266218 scopus 로고
    • Purified bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to it in vitro
    • Vigier, B., F. Watrin, S. Magre, D. Tran, and N. Josso. 1987. Purified bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to it in vitro. Development 100: 43-55.
    • (1987) Development , vol.100 , pp. 43-55
    • Vigier, B.1    Watrin, F.2    Magre, S.3    Tran, D.4    Josso, N.5
  • 52
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 (BMP-4) is required for mesoderm formation and patterning in the mouse
    • Winnier, G., M. Blessing, P.A. Labosky, and B.L.M. Hogan. 1995. Bone morphogenetic protein-4 (BMP-4) is required for mesoderm formation and patterning in the mouse. Genes & Dev. 9: 2105-2116.
    • (1995) Genes & Dev. , vol.9 , pp. 2105-2116
    • Winnier, G.1    Blessing, M.2    Labosky, P.A.3    Hogan, B.L.M.4
  • 55
    • 0029850112 scopus 로고    scopus 로고
    • Mice deficient for BMP-2 are non-viable and have defects in amnion/chorion and cardiac development
    • Zhang, H. and A. Bradley. 1996. Mice deficient for BMP-2 are non-viable and have defects in amnion/chorion and cardiac development. Development 122: 2977-2986.
    • (1996) Development , vol.122 , pp. 2977-2986
    • Zhang, H.1    Bradley, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.