Expression and subcellular localization of SF-1, SOX9, WT1, and AMH proteins during early human testicular development

Developmental Dynamics

Volumn 217, Issue 3, 2000, Pages 293-298

  De Santa Barbara, Pascal ^a,b   Moniot, Brigitte ^a   Poulat, Francis ^a   Berta, Philippe ^a,c  

^a INSTITUTE OF HUMAN GENETICS   (France)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c CNRS   (France)

Author keywords

AMH; Human embryo; Immunohistochemistry; MIS; Sex determination; SF 1; SOX9; WT1

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; EMBRYO DEVELOPMENT; GENE LOCATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SERTOLI CELL; SEX DETERMINATION; STEROIDOGENESIS; TESTIS DEVELOPMENT; TRANSCRIPTION REGULATION;

DNA-BINDING PROTEINS; FUSHI TARAZU TRANSCRIPTION FACTORS; GLYCOPROTEINS; GROWTH INHIBITORS; HIGH MOBILITY GROUP PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MALE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SUBCELLULAR FRACTIONS; TESTICULAR HORMONES; TESTIS; TRANSCRIPTION FACTORS; WT1 PROTEINS;

EUTHERIA; MAMMALIA;

EID: 0034050638     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(200003)217:3<293::AID-DVDY7>3.0.CO;2-P     Document Type: Article

References (29)

1. Cox R, Peifer M. 1998. Wingless signaling: the inconvenient complexities of life. Curr Biol 8:R140-R144.
2. de Santa Barbara P, Bonneaud N, Boizet B, Desclozeaux M, Moniot B, Sudbeck P, Scherer G, Poulat F, Berta P. 1998a. Direct interaction of SRY-related protein SOX9 and steroidogenic factor-1 regulates transcription of the human anti-Müllerian hormone gene. Mol Cell Biol 18:6653-6665.
3. de Santa Barbara P, Moniot B, Poulat F, Boizet B, Berta P. 1998b. Steroidogenic factor-1 regulates transcription of the human anti-Müllerian hormone receptor. J Biol Chem 273:29654-29660.
4. Foster JW, Dominguez-Steglich MA, Guioli S, Kwok C, Weller PA, Stevanovic M, Weissenbach J, Mansour S, Young ID, Goodfellow PN, Brook JD, Schafer AJ. 1994. Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 372:525-530.
5. Giuli G, Shen WH, Ingraham HA. 1997. The nuclear receptor SF-1 mediates sexually dimorphic expression of Müllerian inhibiting substance, in vivo. Development 124:1799-1807.
6. Hanley NA, Ball SG, Clement-Jones M, Hagan DM, Strachan T, Lindsay S, Robson S, Ostrer H, Parker KL, Wilson DI. 1999. Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination. Mech Dev 87:175-180.
7. Hatano O, Takayama K, Imai T, Waterman MR, Takakusu A, Omura T, Morohashi KI. 1994. Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. Development 120: 2787-2797.
8. Ikeda Y, Shen WH, Ingraham HA, Parker KL. 1994. Development expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol 94:654-662.
9. Josso N, Lamarre I, Picard JY, Berta P, Davies N, Morichon N, Peschanski M, Jeny R. 1993. Anti-Müllerian hormone in early human development. Early Hum Dev 33:91-99.
10. Kent J, Wheatley SC, Andrews JE, Sinclair AH, Koopman P. 1996. A male-specific role for SOX9 in vertebrate sex determination. Development 122:2813-2822.
11. Ketola I, Rahman N, Toppari J, Bielinska M, Porter-Tinge SB, Tapanainen JS, Huhtaniemi IT, Wilson DB, Heikinheimo M. 1999. Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology 140:1470-1480.
12. Lefebvre V, de Crombrugghe B. 1998. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol 16:529-540.
13. Ma Y, Niemitz EL, Nambu PA, Shan X, Sackerson C, Fujioka M, Goto T, Nambu JR. 1998. Gene regulatory functions of Drosophila Fishhook, a high mobility group domain Sox protein. Mech Dev 73:168-182.
14. Morais da Silva S, Hacker A, Harley V, Goodfellow P, Swain A, Lovell-Badge R. 1996. Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat Genet 14:62-68.
15. Nachtigal MW, Hirokawa Y, Enyeart-VanHouten DL, Flanagan JN, Hammer GD, Ingraham HA. 1998. Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell 93:445-454.
16. O'Rahilly R. 1983. The timing and sequence of events in the development of the human reproductive system during the embryonic period proper. Anat Embryol 166:247-261.
17. Oreal E, Pieau C, Mattei M-G, Josso N, Picard J-Y, Carré-Eusèbe D, Magre S. 1998. Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expression. Dev Dyn 212:522-532.
18. Poulat F, Girard F, Chevron MP, Gozé C, Rebillard X, Calas B, Lamb N, Berta P. 1995. Nuclear localization of the testis determining gene product SRY. J Cell Biol 5:737-748.
19. Schafer AJ, Goodfellow PN. 1996. Sex determination in humans. Bioessays 18:955-963.
20. Shen WH, Moore CCD, Ikeda Y, Parker KL, Ingraham HA. 1994. Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: a link to the sex determination cascade. Cell 77:651-661.
21. Smith CA, Smith MJ, Sinclair AH. 1999. Gene expression during gonadogenesis in the chicken embryo. Gene 234:395-402.
22. Soullier S, Jay P, Poulat F, Vanacker JM, Berta P, Laudet V. 1999. Diversification pattern of the HMG and SOX family members during evolution. J Mol Evol 48:517-527.
23. Südbeck P, Scherer G. 1997. Two independent nuclear localization signals are present in the DNA-binding high mobility group domains of SRY and SOX9. J Biol Chem 272:27848-27852.
24. Swain A, Lovell-Badge R. 1999. Mammalian sex determination. Genes Dev 13:755-767.
25. Tremblay JJ, Viger RS. 1999. Transcription factor GATA-4 enhances Müllerian inhibiting substance gene transcription through a direct interaction with the nuclear receptor SF-1. Mol Endocrinol 13: 1388-1401.
26. Viger RS, Mertineit C, Trasler JM, Nemer M. 1998. Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter. Development 125:2665-2675.
27. Wagner T, Wirth J, Meyer J, Zabel B, Held M, Zimmer J, Pasantes J, Bricarelli FD, Keutel J, Hustert E, Wolf U, Tommerup N, Schempp W, Scherer G. 1994. Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY related gene SOX9. Cell 79:1111-1120.
28. Wen W, Meinkoth JL, Tsien RY, Taylor SS. 1995. Identification of a signal for rapid export of proteins from the nucleus. Cell 82:463-473.
29. Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE. 1999. Regulation of Wnt signaling by SOX proteins: Xsox17α/β and Xsox3 physically interact with β-catenin. Mol Cell 4:487-498.