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Volumn 3, Issue 12 II, 1997, Pages 2571-2580

The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Mullerian-inhibiting substance, and the androgen receptor

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; MUELLERIAN INHIBITING FACTOR;

EID: 0031417853     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (96)

References (52)
  • 1
    • 0021021175 scopus 로고
    • Childhood cancer incidence: Geographical and temporal variations
    • Breslow, N. E., and Langholz, B. Childhood cancer incidence: geographical and temporal variations. Int. J. Cancer, 32: 703-716, 1983.
    • (1983) Int. J. Cancer , vol.32 , pp. 703-716
    • Breslow, N.E.1    Langholz, B.2
  • 2
    • 0023880214 scopus 로고
    • Age distribution of Wilms' tumor: Report from the national Wilms' tumor study
    • Breslow, N. E., Beckwith, J. B., Ciol, M., and Sharples, K. Age distribution of Wilms' tumor: report from the national Wilms' tumor study. Cancer Res., 48: 1653-1657, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1653-1657
    • Breslow, N.E.1    Beckwith, J.B.2    Ciol, M.3    Sharples, K.4
  • 3
    • 0020032418 scopus 로고
    • Epidemiological features of Wilms' tumor: Results of the National Wilms' tumor study
    • Breslow, N. E., and Beckwith, J. B. Epidemiological features of Wilms' tumor: results of the National Wilms' tumor study. J. Natl. Cancer Instit., 68: 429-436, 1982.
    • (1982) J. Natl. Cancer Instit. , vol.68 , pp. 429-436
    • Breslow, N.E.1    Beckwith, J.B.2
  • 9
    • 0026588871 scopus 로고
    • The genomic organization and expression of the WT1 gene
    • Gessler, M., König, A., and Bruns, G. A. P. The genomic organization and expression of the WT1 gene. Genomics, 12: 807-813, 1992.
    • (1992) Genomics , vol.12 , pp. 807-813
    • Gessler, M.1    König, A.2    Bruns, G.A.P.3
  • 11
    • 0029866180 scopus 로고    scopus 로고
    • Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation
    • Hewitt, S. M., Fraizer, G. C., Wu, Y-J., Rauscher, F. J., III, and Saunders, G. F. Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation. J. Biol. Chem., 271: 8588-8592, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8588-8592
    • Hewitt, S.M.1    Fraizer, G.C.2    Wu, Y.-J.3    Rauscher III, F.J.4    Saunders, G.F.5
  • 12
    • 0025605969 scopus 로고
    • Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence
    • Washington DC
    • Rauscher, F. J., III, Morris, J. F., Tournay, O. E., Cook, D. M., and Curran, T. Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence. Science (Washington DC), 250: 1259-1262, 1990.
    • (1990) Science , vol.250 , pp. 1259-1262
    • Rauscher III, F.J.1    Morris, J.F.2    Tournay, O.E.3    Cook, D.M.4    Curran, T.5
  • 15
  • 17
    • 0028784479 scopus 로고
    • Snaring the genes that divide the sexes for mammals
    • Washington DC
    • Marx, J. Snaring the genes that divide the sexes for mammals. Science (Washington DC), 269: 1824-1825, 1995.
    • (1995) Science , vol.269 , pp. 1824-1825
    • Marx, J.1
  • 18
    • 0028324182 scopus 로고
    • Ovary? Testis? A mammalian dilemma
    • Bogan, J. S., and Page, D. C. Ovary? Testis? A mammalian dilemma. Cell, 76: 603-607, 1994.
    • (1994) Cell , vol.76 , pp. 603-607
    • Bogan, J.S.1    Page, D.C.2
  • 19
    • 0026526495 scopus 로고
    • The Wilms' tumor gene product, WT1, represses transcription of the platelet-derived growth factor A-chain gene
    • Wang, Z-Y., Madden, S. L., Deuel, T. F., and Rauscher, F. J., III. The Wilms' tumor gene product, WT1, represses transcription of the platelet-derived growth factor A-chain gene. J. Biol. Chem., 267: 21999-22002, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21999-22002
    • Wang, Z.-Y.1    Madden, S.L.2    Deuel, T.F.3    Rauscher III, F.J.4
  • 20
    • 0026669131 scopus 로고
    • Repression of the insulin-like growth factor II gene by the Wilms' tumor suppressor WT1
    • Washington DC
    • Drummond, I. A., Madden, S. L., Rohwer-Nutter, P., Bell, G. I., Sukhatme, V. P., and Rauscher, F. J., III. Repression of the insulin-like growth factor II gene by the Wilms' tumor suppressor WT1. Science (Washington DC), 257: 674-678, 1992.
    • (1992) Science , vol.257 , pp. 674-678
    • Drummond, I.A.1    Madden, S.L.2    Rohwer-Nutter, P.3    Bell, G.I.4    Sukhatme, V.P.5    Rauscher III, F.J.6
  • 21
    • 0028304008 scopus 로고
    • Repression of the transforming growth factor-β 1 gene by the Wilms' tumor suppressor WT1 gene product
    • Dey, B. R., Sukhatme, V. P., Roberts, A. B., Sporn, M. B., Rauscher, F. J., III, and Kim, S-J. Repression of the transforming growth factor-β 1 gene by the Wilms' tumor suppressor WT1 gene product. Mol. Endcrinol., 8: 595-602, 1994.
    • (1994) Mol. Endcrinol. , vol.8 , pp. 595-602
    • Dey, B.R.1    Sukhatme, V.P.2    Roberts, A.B.3    Sporn, M.B.4    Rauscher III, F.J.5    Kim, S.-J.6
  • 22
    • 0027384536 scopus 로고
    • Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus
    • Harrington, M. A., Konicek, B., Song, A., Xia, Z-L., Fredricks, W. J., and Rauscher, F. J., III. Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. J. Biol. Chem., 268: 1271-21275, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1271-21275
    • Harrington, M.A.1    Konicek, B.2    Song, A.3    Xia, Z.-L.4    Fredricks, W.J.5    Rauscher III, F.J.6
  • 23
    • 0028318393 scopus 로고
    • Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site
    • Werner, H., Rauscher, F. J., III., Sukhatme, V. P., Drummond, I. A., Roberts, C. T., and LeRoith, D. Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site. J. Biol. Chem., 269: 12577-12582, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12577-12582
    • Werner, H.1    Rauscher III, F.J.2    Sukhatme, V.P.3    Drummond, I.A.4    Roberts, C.T.5    LeRoith, D.6
  • 24
    • 0028967215 scopus 로고
    • Repression of the retinoic acid receptor-α gene by the Wilms' tumor suppressor gene product, wt1
    • Goodyer, P., Dehbi, M., Torban, E., Bruening, W., and Pelletier, J. Repression of the retinoic acid receptor-α gene by the Wilms' tumor suppressor gene product, wt1. Oncogene, 10: 1125-1129, 1995.
    • (1995) Oncogene , vol.10 , pp. 1125-1129
    • Goodyer, P.1    Dehbi, M.2    Torban, E.3    Bruening, W.4    Pelletier, J.5
  • 26
    • 0028844582 scopus 로고
    • Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1
    • Hewitt, S. M., Hamada, S., McDonnell, T. J., Rauscher, F. J., III, and Saunders, G. F. Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1. Cancer Res., 55: 5386-5389, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5386-5389
    • Hewitt, S.M.1    Hamada, S.2    McDonnell, T.J.3    Rauscher III, F.J.4    Saunders, G.F.5
  • 27
    • 0027526498 scopus 로고
    • Identification of the transcriptional unit, structural organization, and promoter sequence of the human sex-determining region Y (SRY) gene, using a reverse genetic approach
    • Su, H., and Lau, Y-F. C. Identification of the transcriptional unit, structural organization, and promoter sequence of the human sex-determining region Y (SRY) gene, using a reverse genetic approach. Am. J. Hum. Genet., 52: 24-38, 1993.
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 24-38
    • Su, H.1    Lau, Y.-F.C.2
  • 28
    • 0027238681 scopus 로고
    • Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1
    • Faber, P. W., van Rooji, H. C. J., Schipper, H. J., Brinkmann, A. O., and Trapman, J. Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1. J. Biol. Chem., 268: 9296-9301, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9296-9301
    • Faber, P.W.1    Van Rooji, H.C.J.2    Schipper, H.J.3    Brinkmann, A.O.4    Trapman, J.5
  • 30
    • 0026006382 scopus 로고
    • Transcriptional repression mediated by the WT1 Wilms' tumor gene product
    • Washington DC
    • Madden, S. L., Cook, D. M., Morris, J. F., Gashler, A., Sukhatme, V. P., and Rauscher, F. J., III. Transcriptional repression mediated by the WT1 Wilms' tumor gene product. Science (Washington DC), 253: 1550-1553, 1991.
    • (1991) Science , vol.253 , pp. 1550-1553
    • Madden, S.L.1    Cook, D.M.2    Morris, J.F.3    Gashler, A.4    Sukhatme, V.P.5    Rauscher III, F.J.6
  • 31
    • 0028206250 scopus 로고
    • Transcriptional Regulation of the Human Wilms' Tumor Gene (WT1): Constitutive Promoter and a Tissue Specific Enhancer
    • Fraizer, G. C., Wu, Y-J., Hewitt, S. M., Maity, T., Ton, C. C. T., Huff, V., and Saunders, G. F. Transcriptional Regulation of the Human Wilms' Tumor Gene (WT1): constitutive Promoter and a Tissue Specific Enhancer. J. Biol. Chem., 269: 8892-8900, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8892-8900
    • Fraizer, G.C.1    Wu, Y.-J.2    Hewitt, S.M.3    Maity, T.4    Ton, C.C.T.5    Huff, V.6    Saunders, G.F.7
  • 32
    • 0025773296 scopus 로고
    • Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1A
    • Washington DC
    • Pavletich, N. P., and Pabo, C. O. Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1A. Science (Washington DC), 252: 809-817, 1991.
    • (1991) Science , vol.252 , pp. 809-817
    • Pavletich, N.P.1    Pabo, C.O.2
  • 33
    • 0028308118 scopus 로고
    • Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: A link to the sex determination cascade
    • Shen, W-H., Moore, C. C. D., Ikeda, Y., Parker, K. L., and Ingraham, H. A. Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: a link to the sex determination cascade. Cell, 77: 651-661, 1994.
    • (1994) Cell , vol.77 , pp. 651-661
    • Shen, W.-H.1    Moore, C.C.D.2    Ikeda, Y.3    Parker, K.L.4    Ingraham, H.A.5
  • 34
    • 0028107468 scopus 로고
    • Identification of 3′, 5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter
    • Mizokami, A., Yeh, S-Y., and Chang, C. Identification of 3′, 5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter. Mol. Endocrinol., 8: 77-88, 1994.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 77-88
    • Mizokami, A.1    Yeh, S.-Y.2    Chang, C.3
  • 37
    • 0025243412 scopus 로고
    • Expression of a candidate sex-determining gene during mouse testis differentiation
    • Koopman, P., Munsterberg, A., Capel, B., Vivian, N., and Lovell-Badge, R. Expression of a candidate sex-determining gene during mouse testis differentiation. Nature (Lond.), 348: 450-452, 1990.
    • (1990) Nature (Lond.) , vol.348 , pp. 450-452
    • Koopman, P.1    Munsterberg, A.2    Capel, B.3    Vivian, N.4    Lovell-Badge, R.5
  • 38
    • 0030891372 scopus 로고    scopus 로고
    • A clinical overview of WT1 gene mutations
    • Little, M., and Wells, C. A clinical overview of WT1 gene mutations. Hum. Mutat., 9: 209-225, 1997.
    • (1997) Hum. Mutat. , vol.9 , pp. 209-225
    • Little, M.1    Wells, C.2
  • 39
    • 0028172159 scopus 로고
    • Müllerian-inhibiting substance function during mammalian sexual development
    • Behringer, R. R., Finegold, M. J., and Cate, R. L. Müllerian-inhibiting substance function during mammalian sexual development. Cell, 79: 415-425, 1994.
    • (1994) Cell , vol.79 , pp. 415-425
    • Behringer, R.R.1    Finegold, M.J.2    Cate, R.L.3
  • 40
    • 0029048140 scopus 로고
    • Expression of Sry, the mouse sex determining gene
    • Camb.
    • Hacker, A., Capel, B., Goodfellow, P., and Lovell-Badge, R. Expression of Sry, the mouse sex determining gene. Development (Camb.), 121: 1603-1614, 1994.
    • (1994) Development , vol.121 , pp. 1603-1614
    • Hacker, A.1    Capel, B.2    Goodfellow, P.3    Lovell-Badge, R.4
  • 42
    • 0025312139 scopus 로고
    • Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance
    • Behringer, R. R., Cate, R. L., Froelick, G. T., Palmiter, R. D., and Brinster, R. L. Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance. Nature (Lond.), 345: 167-170, 1990.
    • (1990) Nature (Lond.) , vol.345 , pp. 167-170
    • Behringer, R.R.1    Cate, R.L.2    Froelick, G.T.3    Palmiter, R.D.4    Brinster, R.L.5
  • 43
    • 0028903902 scopus 로고
    • WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins
    • Reddy, J. C., Morris, J. C., Wang, J., English, M. A., Haber, D. A., Shi, Y., and Licht, J. D. WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins. J. Biol. Chem., 270: 10878-10884, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10878-10884
    • Reddy, J.C.1    Morris, J.C.2    Wang, J.3    English, M.A.4    Haber, D.A.5    Shi, Y.6    Licht, J.D.7
  • 45
    • 0026968890 scopus 로고
    • Molecular biology of disorders of sex differentiation
    • Basel
    • Sultan, C., Lobaccaro, J. M., Belon, C., Terraza, A., and Lumbroso, S. Molecular biology of disorders of sex differentiation. Horm. Res. (Basel), 38: 105-113, 1992.
    • (1992) Horm. Res. , vol.38 , pp. 105-113
    • Sultan, C.1    Lobaccaro, J.M.2    Belon, C.3    Terraza, A.4    Lumbroso, S.5
  • 46
    • 33747640635 scopus 로고
    • The syndrome of testicular feminization in male pseudohermaphrodites
    • Morris, J. M. The syndrome of testicular feminization in male pseudohermaphrodites. Am. J. Obstet. Gynecol., 65: 1192-1211, 1953.
    • (1953) Am. J. Obstet. Gynecol. , vol.65 , pp. 1192-1211
    • Morris, J.M.1
  • 47
    • 0025743234 scopus 로고
    • Androgen receptor expression in developing male reproductive organs
    • Cooke, P. S., Young, P., and Cunha, G. R. Androgen receptor expression in developing male reproductive organs. Endocrinology, 128: 2867-2873, 1991.
    • (1991) Endocrinology , vol.128 , pp. 2867-2873
    • Cooke, P.S.1    Young, P.2    Cunha, G.R.3
  • 48
    • 0029150932 scopus 로고
    • Quantitative analysis of androgen receptor messenger ribonucleic acid in developing Leydig cells and Sertoli cells by in situ hybridization
    • Shan, L-X., Zhu, L-J., Bardin, W., and Hardy, M. P. Quantitative analysis of androgen receptor messenger ribonucleic acid in developing Leydig cells and Sertoli cells by in situ hybridization. Endocrinology, 136: 3856-3862, 1995.
    • (1995) Endocrinology , vol.136 , pp. 3856-3862
    • Shan, L.-X.1    Zhu, L.-J.2    Bardin, W.3    Hardy, M.P.4
  • 49
    • 0027286309 scopus 로고
    • The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains
    • Wang, Z-Y., Qui, Q-Q., and Duel, T. F. The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains. J. Biol. Chem., 268: 9172-9175, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9172-9175
    • Wang, Z.-Y.1    Qui, Q.-Q.2    Duel, T.F.3
  • 50
    • 0029560249 scopus 로고
    • The transcriptional effect of WT1 is modulated by choice of expression vector
    • Reddy, J. C., Hosono, S., and Licht, J. D. The transcriptional effect of WT1 is modulated by choice of expression vector. J. Biol. Chem., 270: 29976-29982, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29976-29982
    • Reddy, J.C.1    Hosono, S.2    Licht, J.D.3
  • 51
    • 0028897181 scopus 로고
    • Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways
    • Wang, Z-Y., Qui, Q-Q., Huang, J., Gurrieri, M., and Duel, T. F. Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways. Oncogene, 10: 415-422, 1995.
    • (1995) Oncogene , vol.10 , pp. 415-422
    • Wang, Z.-Y.1    Qui, Q.-Q.2    Huang, J.3    Gurrieri, M.4    Duel, T.F.5


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