Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy

Brain

Volumn 134, Issue 1, 2011, Pages 220-234

  Giordano, Carla ^a   Montopoli, Monica ^b   Perli, Elena ^a   Orlandi, Maurizia ^a   Fantin, Marianna ^c   Ross Cisneros, Fred N ^d   Caparrotta, Laura ^b   Martinuzzi, Andrea ^c   Ragazzi, Eugenio ^b   Ghelli, Anna ^e   Sadun, Alfredo A ^d   D'Amati, Giulia ^a   Carelli, Valerio ^e  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c SCIENTIFIC INSTITUTE   (Italy)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

LHON; mitochondrial disorders; oestrogen; oestrogen receptors; oxidative stress

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR BETA; FULVESTRANT; GALACTOSE; GLUCOSE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ADD ON THERAPY; APOPTOSIS; ARTICLE; BIOGENESIS; CELL LOSS; CELL METABOLISM; CELL STRUCTURE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYBRID; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE ACTIVATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; LEBER HEREDITARY OPTIC NEUROPATHY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION; NUCLEAR LOCALIZATION SIGNAL; OXYGEN CONSUMPTION; POINT MUTATION; PREVALENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINA GANGLION CELL; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; DNA, MITOCHONDRIAL; ESTRADIOL; ESTROGENS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OPTIC ATROPHY, HEREDITARY, LEBER; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE;

EID: 78650693389     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq276     Document Type: Article

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