Decreased mitochondrial DNA mutagenesis in human colorectal cancer

PLoS Genetics

Volumn 8, Issue 6, 2012, Pages

  Ericson, Nolan G ^a   Kulawiec, Mariola ^a   Vermulst, Marc ^b   Sheahan, Kieran ^c   O'Sullivan, Jacintha ^c   Salk, Jesse J ^d   Bielas, Jason H ^a,d  

^a Fred Hutchinson Cancer Research Center   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; GLUCOSE;

ADULT; AGED; ANAEROBIC GLYCOLYSIS; ARTICLE; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA DAMAGE; FEMALE; GENE FREQUENCY; GENE MUTATION; GLUCOSE METABOLISM; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRIAL GENOME; MUTAGENESIS; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; COLORECTAL TUMOR; GENETICS; GENOMIC INSTABILITY; GLYCOLYSIS; METABOLISM; MIDDLE AGED; POINT MUTATION;

AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA, MITOCHONDRIAL; FEMALE; GENOMIC INSTABILITY; GLUCOSE; GLYCOLYSIS; HUMANS; MALE; MIDDLE AGED; MUTAGENESIS; OXIDATIVE STRESS; POINT MUTATION; REACTIVE OXYGEN SPECIES;

EID: 84864039117     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002689     Document Type: Article

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