Different characteristics of mitochondrial microsatellite instability between uterine leiomyomas and leiomyosarcomas

Pathology and Oncology Research

Volumn 17, Issue 2, 2011, Pages 201-205

  Lee, Jae Ho ^a   Ryu, Tae Yung ^a   Cho, Chi Heum ^a   Kim, Dae Kwang ^a,b  

^a Keimyung University   (South Korea)

^b Keimyung University School of Medicine   (South Korea)

Author keywords

Genetic instability; Mitochondrial microsatellite instability; Uterine leiomyoma; Uterine leiomyosarcomas

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DNA SEQUENCE; FEMALE; GENE DELETION; GENE INSERTION; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; LEIOMYOSARCOMA; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MICROSATELLITE MARKER; MITOCHONDRIAL GENETICS; UTERUS MYOMA;

BASE SEQUENCE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LEIOMYOMA; LEIOMYOSARCOMA; MICROSATELLITE INSTABILITY; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; TUMOR MARKERS, BIOLOGICAL; UTERINE NEOPLASMS;

EID: 80051664077     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-010-9297-z     Document Type: Article

References (36)

1. Cramer SF, Patel A (1990) The frequency of uterine leiomyomas. Am J Clin Pathol 94:435-438 (Pubitemid 20316570)
2. Parker WH (2007) Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril 87:725-736 (Pubitemid 46553757)
3. Walker CL, Stewart EA (2005) Uterine fibroids: the elephant in the room. Science 308:1589-1592 (Pubitemid 40807499)
4. Chen L, Yang B (2008) Immunohistochemical analysis of p16, p53, and Ki-67 expression in uterine smooth muscle tumors. Int J Gynecol Pathol 27:326-332
5. Packenham JP, du Manoir S, Schrock E et al (1997) Analysis of genetic alterations in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization. Mol Carcinog 19:273-279 (Pubitemid 27392007)
6. Thibodeau S, Bren G, Schaid D (1993) Microsatellite instability in cancer of the proximal colon. Science 75:1027-1038
7. Brenmall T (1995) Microsatellite instability-Shifting concepts in tumorigenesis. Am J Path 147:561-563
8. Boland CR, Thibodeau SN, Hamilton SR et al (1998) A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58:5248-5257 (Pubitemid 28521189)
9. Naidoo R, Chetty R (1998) The application of microsatellites in molecular pathology. Pathol Oncol Res 4:310-315 (Pubitemid 29081104)
10. Quade BJ, Pinto AP, Howard DR et al (1999) Frequent loss of heterozygosity for chromosome 10 in uterine leiomyosarcoma in contrast to leiomyoma. Am J Pathol 154:945-950 (Pubitemid 29122614)
11. Suwa K, Ohmori M, Miki H (1999) Microsatellite alterations in various sarcomas in Japanese patients. J Orthop Sci 4:223-230 (Pubitemid 29274700)
12. Amant F, Dorfling CM, Dreyer L et al (2001) Microsatellite instability in uterine sarcomas. Int J Gynecol Cancer 11:218-223 (Pubitemid 32624385)
13. Howell N, Kubacka I, Mackey DA (1996) How rapidly does the human mitochondrial genome evolve? Am J Hum Genet 59:501-509 (Pubitemid 26269027)
14. Pääbo S (1996) Mutational hot spots in the mitochondrial microcosm. Am J Hum Genet 59:493-496 (Pubitemid 26269025)
15. Khrapko K, Coller HA, André PC et al (1997) Mitochondrial mutational spectra in human cells and tissues. Proc Natl Acad Sci USA 94:13798-13803 (Pubitemid 28009664)
16. Richard SM, Bailliet G, Páez GL et al (2000) Nuclear and mitochondrial genome instability in human breast cancer. Cancer Res 60:4231-4237 (Pubitemid 30636610)
17. Bianchi NO, Bianchi MS, Richard SM (2001) Mitochondrial genome instability in human cancers. Mutat Res 488:9-23 (Pubitemid 32166780)
18. Wang Y, Liu VW, Ngan HY et al (2005) Frequent occurrence of mitochondrial microsatellite instability in the D-loop region of human cancers. Ann N Y Acad Sci 1042:123-129 (Pubitemid 40967629)
19. Wang Y, Liu VW, Tsang PC et al (2006) Microsatellite instability in mitochondrial genome of common female cancers. Int J Gynecol Cancer 16:259-266
20. Habano W, Nakamura S, Sugai T (1998) Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome. Oncogene 17:1931-1937 (Pubitemid 28488461)
21. Lee JH, Choi IJ, Song DK et al (2010) Genetic instability in the human lymphocyte exposed to hypoxia. Cancer Genet Cytogenet 196:83-88
22. Jeong CW, Lee JH, Sohn SS et al (2010) Mitochondrial microsatellite instability in gastric cancer and gastric epithelial dysplasia as a precancerous lesion. Cancer Epidemiol 34:323-327
23. Bell SW, Kempson RL, Hendrickson MR (1994) Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol 18:535-558 (Pubitemid 24150803)
24. Ha TW, Han KH, Son DG et al (2005) Analysis of loss of heterozygosity in Korean patients with keratoacanthoma. J Korean Med Sci 20:340-343
25. Fletcher JA, Morton CC, Paelka K et al (1990) Chromosome aberration in uterine smooth muscle tumors: potential diagnostic relevance of cytogenetic instability. Cancer Res 50:4092-4097 (Pubitemid 20225636)
26. Laxman R, Currie JL, Kurman RJ et al (1993) Cytogenetic profile of uterine sarcomas. Cancer 71:1283-1288 (Pubitemid 23054920)
27. Sreekantaiah C, Davis JR, Sandberg AA (1993) Chromosomal abnormalities in leiomyosarcomas. Am J Pathol 142:293-305 (Pubitemid 23026932)
28. Pandis N, Heim S, Bardi G et al (1991) Chromosome analysis of 96 uterine leiomyomas. Cancer Genet Cytogenet 55:11-18
29. Heim S, Nilbert M, Vanni R et al (1988) A specific translocation, t (12;14) (q14-15;q23-24), characterizes a subgroup of uterine leiomyomas. Cancer Genet Cytogenet 32:13-17
30. Ozisik YY, Meloni AM, Surti U et al (1993) Deletion 7q22 in uterine leiomyoma: a cytogenetic review. Cancer Genet Cytogenet 71:1-6 (Pubitemid 24032320)
31. Mittal KR, Chen F, Wei JJ et al (2009) Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyoma-like areas. Mod Pathol 22:1303-1311
32. French D, Cermele C, Lombardi AM et al (1998) Microsatellite alterations in uterine leiomyomas. Anticancer Res 18:349-352
33. Risinger JI, Umar A, Boyer JC et al (1995) Microsatellite instability in gynecological sarcomas and in hMSH2 mutant uterine sarcoma cell lines defective in mismatch repair activity. Cancer Res 55:5664-5669
34. Stoneking M (2000) Hypervariable sites in the mtDNA control region are mutational hotspots. Am J Hum Genet 67:1029-1032
35. Lièvre A, Chapusot C, Bouvier AM et al (2005) Clinical value of mitochondrial mutations in colorectal cancer. J Clin Oncol 23:3517-3525
36. Lee HC, Yin PH, Lin JC et al (2005) Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci 104:109-122