Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 32, 2010, Pages 14122-14127

  Brannigan, Grace ^a   LeBard, David N ^a   Hénin, Jérôme ^b   Eckenhoff, Roderic G ^c   Klein, Michael L ^a  

^a Temple University   (United States)

^b AIX MARSEILLE UNIVERSITY   (France)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anesthesia; Cys loop receptor; Ligand gated ion channel

Indexed keywords

ISOFLURANE; NICOTINIC RECEPTOR; ANESTHETIC AGENT; BACTERIAL PROTEIN; ION CHANNEL; MEMBRANE LIPID; MEMBRANE PROTEIN;

ARTICLE; LIPID MEMBRANE; MOLECULAR DYNAMICS; MUTAGENESIS; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RECEPTOR BINDING; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ANESTHETICS, GENERAL; BACTERIAL PROTEINS; BINDING SITES; ION CHANNELS; ISOFLURANE; MEMBRANE LIPIDS; MEMBRANE PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC;

EID: 77956275726     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1008534107     Document Type: Article

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