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Volumn 762, Issue , 2013, Pages 239-261

HIV-derived vectors for gene therapy targeting dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BLOOD CLOTTING FACTOR 9; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DACLIZUMAB; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ANTIBODY; LENTIVIRUS VECTOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TACROLIMUS; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

EID: 84869062794     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-4433-6-9     Document Type: Article
Times cited : (8)

References (138)
  • 3
    • 15244351083 scopus 로고    scopus 로고
    • Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
    • DOI 10.1038/nbt1049
    • Amendola M, Venneri MA, Biffi A, Vigna E, Naldini L (2005) Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol 23(1):108-116 (Pubitemid 41724633)
    • (2005) Nature Biotechnology , vol.23 , Issue.1 , pp. 108-116
    • Amendola, M.1    Venneri, M.A.2    Biffi, A.3    Vigna, E.4    Naldini, L.5
  • 4
    • 67349250445 scopus 로고    scopus 로고
    • Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform
    • Amendola M, Passerini L, Pucci F, Gentner B, Bacchetta R, Naldini L (2009) Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform. Mol Ther 17(6):1039-1052
    • (2009) Mol Ther , vol.17 , Issue.6 , pp. 1039-1052
    • Amendola, M.1    Passerini, L.2    Pucci, F.3    Gentner, B.4    Bacchetta, R.5    Naldini, L.6
  • 6
    • 34548832740 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1182/blood-2006-11-059873
    • Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L et al (2007) The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen- presenting cells but not by CD4+ CD25+ regulatory T cells. Blood 110(6):1788-1796 (Pubitemid 47443889)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1788-1796
    • Annoni, A.1    Battaglia, M.2    Follenzi, A.3    Lombardo, A.4    Sergi-Sergi, L.5    Naldini, L.6    Roncarolo, M.-G.7
  • 7
    • 73949157699 scopus 로고    scopus 로고
    • In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance
    • Annoni A, Brown BD, Cantore A, Sergi LS, Naldini L, Roncarolo MG (2009) In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance. Blood 114(25):5152-5161
    • (2009) Blood , vol.114 , Issue.25 , pp. 5152-5161
    • Annoni, A.1    Brown, B.D.2    Cantore, A.3    Sergi, L.S.4    Naldini, L.5    Roncarolo, M.G.6
  • 8
    • 69949173615 scopus 로고    scopus 로고
    • Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization
    • Arce F, Rowe HM, Chain B, Lopes L, Collins MK (2009) Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization. Mol Ther 17(9):1643-1650
    • (2009) Mol Ther , vol.17 , Issue.9 , pp. 1643-1650
    • Arce, F.1    Rowe, H.M.2    Chain, B.3    Lopes, L.4    Collins, M.K.5
  • 9
    • 69949184405 scopus 로고    scopus 로고
    • Strategies to modulate immune responses: A new frontier for gene therapy
    • Arruda VR, Favaro P, Finn JD (2009) Strategies to modulate immune responses: a new frontier for gene therapy. Mol Ther 17(9):1492-1503
    • (2009) Mol Ther , vol.17 , Issue.9 , pp. 1492-1503
    • Arruda, V.R.1    Favaro, P.2    Finn, J.D.3
  • 10
    • 33845994066 scopus 로고    scopus 로고
    • + hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication
    • DOI 10.1038/sj.mt.6300025, PII 6300025
    • Bahner I, Sumiyoshi T, Kagoda M, Swartout R, Peterson D, Pepper K et al (2007) Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication. Mol Ther 15(1):76-85 (Pubitemid 46043652)
    • (2007) Molecular Therapy , vol.15 , Issue.1 , pp. 76-85
    • Bahner, I.1    Sumiyoshi, T.2    Kagoda, M.3    Swartout, R.4    Peterson, D.5    Pepper, K.6    Dorey, F.7    Reiser, J.8    Kohn, D.B.9
  • 12
    • 76749152709 scopus 로고    scopus 로고
    • Integrase-defective lentiviral vectors: Progress and applications
    • Banasik MB, McCray PB Jr (2010) Integrase-defective lentiviral vectors: progress and applications. Gene Ther 17(2): 150-157
    • (2010) Gene Ther , vol.17 , Issue.2 , pp. 150-157
    • Banasik, M.B.1    McCray Jr., P.B.2
  • 14
    • 0037217830 scopus 로고    scopus 로고
    • Influence of plasma viremia on defects in number and immunophenotype of blood dendritic cell subsets in human immunodeficiency virus 1-infected individuals
    • DOI 10.1086/345957
    • Barron MA, Blyveis N, Palmer BE, MaWhinney S, Wilson CC (2003) Influence of plasma viremia on defects in number and immunophenotype of blood dendritic cell subsets in human immunodeficiency virus 1-infected individuals. J Infect Dis 187(1):26-37 (Pubitemid 36034468)
    • (2003) Journal of Infectious Diseases , vol.187 , Issue.1 , pp. 26-37
    • Barron, M.A.1    Blyveis, N.2    Palmer, B.E.3    MaWhinney, S.4    Wilson, C.C.5
  • 16
    • 79954733266 scopus 로고    scopus 로고
    • Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection
    • Biffi A, Bartolomae CC, Cesana D, Cartier N, Aubourg P, Ranzani M et al (2011) Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection. Blood 117(20):5332-5339
    • (2011) Blood , vol.117 , Issue.20 , pp. 5332-5339
    • Biffi, A.1    Bartolomae, C.C.2    Cesana, D.3    Cartier, N.4    Aubourg, P.5    Ranzani, M.6
  • 18
    • 60649096118 scopus 로고    scopus 로고
    • Lentiviral vectors for anti-tumor immunotherapy
    • Breckpot K, Emeagi PU, Thielemans K (2008) Lentiviral vectors for anti-tumor immunotherapy. Curr Gene Ther 8(6):438-448
    • (2008) Curr Gene Ther , vol.8 , Issue.6 , pp. 438-448
    • Breckpot, K.1    Emeagi, P.U.2    Thielemans, K.3
  • 19
    • 33646564701 scopus 로고    scopus 로고
    • Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
    • Brown BD, Venneri MA, Zingale A, Sergi Sergi L, Naldini L (2006) Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer. Nat Med 12(5):585-591
    • (2006) Nat Med , vol.12 , Issue.5 , pp. 585-591
    • Brown, B.D.1    Ma, V.2    Zingale, A.3    Sergi Sergi, L.4    Naldini, L.5
  • 20
    • 36849053006 scopus 로고    scopus 로고
    • A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice
    • DOI 10.1182/blood-2007-03-078493
    • Brown BD, Cantore A, Annoni A, Sergi LS, Lombardo A, Della Valle P et al (2007a) A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice. Blood 110(13):4144-4152 (Pubitemid 351377775)
    • (2007) Blood , vol.110 , Issue.13 , pp. 4144-4152
    • Brown, B.D.1    Cantore, A.2    Annoni, A.3    Sergi, L.S.4    Lombardo, A.5    Della Valle, P.6    D'Angelo, A.7    Naldini, L.8
  • 21
    • 33947583453 scopus 로고    scopus 로고
    • In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance
    • DOI 10.1182/blood-2006-10-049312
    • Brown BD, Sitia G, Annoni A, Hauben E, Sergi LS, Zingale A et al (2007b) In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance. Blood 109(7):2797-2805 (Pubitemid 46482074)
    • (2007) Blood , vol.109 , Issue.7 , pp. 2797-2805
    • Brown, B.D.1    Sitia, G.2    Annoni, A.3    Hauben, E.4    Sergi, L.S.5    Zingale, A.6    Roncarolo, M.G.7    Guidotti, L.G.8    Naldini, L.9
  • 22
    • 0035026049 scopus 로고    scopus 로고
    • Primate and feline lentivirus vector RNA packaging and propagation by heterologous lentivirus virions
    • DOI 10.1128/JVI.75.11.5129-5140.2001
    • Browning MT, Schmidt RD, Lew KA, Rizvi TA (2001) Primate and feline lentivirus vector RNA packaging and propagation by heterologous lentivirus virions. J Virol 75(11):5129-5140 (Pubitemid 32448535)
    • (2001) Journal of Virology , vol.75 , Issue.11 , pp. 5129-5140
    • Browning, M.T.1    Schmidt, R.D.2    Lew, K.A.3    Rizvi, T.A.4
  • 23
    • 4644251528 scopus 로고    scopus 로고
    • Evidence for gene expression by unintegrated human immunodeficiency virus type 1 DNA species
    • DOI 10.1128/JVI.78.20.11263-11271.2004
    • Brussel A, Sonigo P (2004) Evidence for gene expression by unintegrated human immunodeficiency virus type 1 DNA species. J Virol 78(20):11263-11271 (Pubitemid 39299665)
    • (2004) Journal of Virology , vol.78 , Issue.20 , pp. 11263-11271
    • Brussel, A.1    Sonigo, P.2
  • 24
    • 0032796643 scopus 로고    scopus 로고
    • Interaction of human immunodeficiency virus-derived vectors with wild- type virus in transduced cells
    • Bukovsky AA, Song JP, Naldini L (1999) Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells. J Virol 73(8):7087-7092 (Pubitemid 29327900)
    • (1999) Journal of Virology , vol.73 , Issue.8 , pp. 7087-7092
    • Bukovsky, A.A.1    Song, J.-P.2    Naldini, L.3
  • 25
    • 2942620287 scopus 로고    scopus 로고
    • + T cell responses induced by dendritic cells generated in the presence of IFN-α
    • Carbonneil C, Donkova-Petrini V, Aouba A, Weiss L (2004) Defective dendritic cell function in HIV-infected patients receiving effective highly active antiretroviral therapy: neutralization of IL-10 production and depletion of CD4+ CD25+ T cells restore high levels of HIV-specific CD4+ T cell responses induced by dendritic cells generated in the presence of IFN-alpha. J Immunol 172(12):7832-7840 (Pubitemid 38747651)
    • (2004) Journal of Immunology , vol.172 , Issue.12 , pp. 7832-7840
    • Carbonneil, C.1    Donkova-Petrini, V.2    Aouba, A.3    Weiss, L.4
  • 26
    • 18144413140 scopus 로고    scopus 로고
    • Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells
    • Chen X, He J, Chang LJ (2004) Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells. Retrovirology 1:37
    • (2004) Retrovirology , vol.1 , pp. 37
    • Chen, X.1    He, J.2    Chang, L.J.3
  • 27
    • 70349254607 scopus 로고    scopus 로고
    • TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type i IFN
    • Di Domizio J, Blum A, Gallagher-Gambarelli M, Molens JP, Chaperot L, Plumas J (2009) TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN. Blood 114(9):1794-1802
    • (2009) Blood , vol.114 , Issue.9 , pp. 1794-1802
    • Di Domizio, J.1    Blum, A.2    Gallagher-Gambarelli, M.3    Molens, J.P.4    Chaperot, L.5    Plumas, J.6
  • 28
    • 77955608799 scopus 로고    scopus 로고
    • RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDSrelated lymphoma
    • DiGiusto DL, Krishnan A, Li L, Li H, Li S, Rao A et al (2010) RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDSrelated lymphoma. Sci Transl Med 2(36):36ra43
    • (2010) Sci Transl Med , vol.2 , Issue.36
    • Digiusto, D.L.1    Krishnan, A.2    Li, L.3    Li, H.4    Li, S.5    Rao, A.6
  • 30
    • 0035889156 scopus 로고    scopus 로고
    • Loss of blood CD11c(+) myeloid and CD11c(+) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load
    • Donaghy H, Pozniak A, Gazzard B, Qazi N, Gilmour J, Gotch F et al (2001) Loss of blood CD11c(+) myeloid and CD11c(+) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load. Blood 98(8):2574-2576
    • (2001) Blood , vol.98 , Issue.8 , pp. 2574-2576
    • Donaghy, H.1    Pozniak, A.2    Gazzard, B.3    Qazi, N.4    Gilmour, J.5    Gotch, F.6
  • 31
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1
    • DOI 10.1182/blood-2002-10-3189
    • Donaghy H, Gazzard B, Gotch F, Patterson S (2003) Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1. Blood 101(11): 4505-4511 (Pubitemid 36857821)
    • (2003) Blood , vol.101 , Issue.11 , pp. 4505-4511
    • Donaghy, H.1    Gazzard, B.2    Gotch, F.3    Patterson, S.4
  • 32
    • 0026515136 scopus 로고
    • Functional characterization of a U5 ribozyme: Intracellular suppression of human immunodeficiency virus type 1 expression
    • Dropulic B, Lin NH, Martin MA, Jeang KT (1992) Functional characterization of a U5 ribozyme: intracellular suppression of human immunodeficiency virus type 1 expression. J Virol 66(3): 1432-1441
    • (1992) J Virol , vol.66 , Issue.3 , pp. 1432-1441
    • Dropulic, B.1    Lin, N.H.2    Ma, M.3    Jeang, K.T.4
  • 34
    • 33645098473 scopus 로고    scopus 로고
    • Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors
    • Dullaers M, Van Meirvenne S, Heirman C, Straetman L, Bonehill A, Aerts JL et al (2006) Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors. Gene Ther 13(7):630-640
    • (2006) Gene Ther , vol.13 , Issue.7 , pp. 630-640
    • Dullaers, M.1    Van Meirvenne, S.2    Heirman, C.3    Straetman, L.4    Bonehill, A.5    Aerts, J.L.6
  • 36
    • 0035169569 scopus 로고    scopus 로고
    • Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes
    • DOI 10.1182/blood.V97.1.114
    • Dyall J, Latouche JB, Schnell S, Sadelain M (2001) Lentivirus-transduced human monocytederived dendritic cells Efficiently stimulate antigen-specific cytotoxic T lymphocytes. Blood 97(1):114-121 (Pubitemid 32061250)
    • (2001) Blood , vol.97 , Issue.1 , pp. 114-121
    • Dyall, J.1    Latouche, J.-B.2    Schnell, S.3    Sadelain, M.4
  • 37
    • 27744489220 scopus 로고    scopus 로고
    • Silencing and variegation of gammaretrovirus and lentivirus vectors
    • DOI 10.1089/hum.2005.16.1241
    • Ellis J (2005) Silencing and variegation of gammaretrovirus and lentivirus vectors. Hum Gene Ther 16(11):1241-1246 (Pubitemid 41611651)
    • (2005) Human Gene Therapy , vol.16 , Issue.11 , pp. 1241-1246
    • Ellis, J.1
  • 40
    • 0036171327 scopus 로고    scopus 로고
    • Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors
    • DOI 10.1089/10430340252769770
    • Follenzi A, Sabatino G, Lombardo A, Boccaccio C, Naldini L (2002) Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors. Hum Gene Ther 13(2):243-260 (Pubitemid 34164109)
    • (2002) Human Gene Therapy , vol.13 , Issue.2 , pp. 243-260
    • Follenzi, A.1    Sabatino, G.2    Lombardo, A.3    Boccaccio, C.4    Naldini, L.5
  • 41
    • 2342561729 scopus 로고    scopus 로고
    • Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice
    • DOI 10.1182/blood-2003-09-3217
    • Follenzi A, Battaglia M, Lombardo A, Annoni A, Roncarolo MG, Naldini L (2004) Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. Blood 103(10): 3700-3709 (Pubitemid 38596285)
    • (2004) Blood , vol.103 , Issue.10 , pp. 3700-3709
    • Follenzi, A.1    Battaglia, M.2    Lombardo, A.3    Annoni, A.4    Roncarolo, M.G.5    Naldini, L.6
  • 42
    • 35349024379 scopus 로고    scopus 로고
    • Immune responses to lentiviral vectors
    • DOI 10.2174/156652307782151515
    • Follenzi A, Santambrogio L, Annoni A (2007) Immune responses to lentiviral vectors. Curr Gene Ther 7(5):306-315 (Pubitemid 47595773)
    • (2007) Current Gene Therapy , vol.7 , Issue.5 , pp. 306-315
    • Follenzi, A.1    Santambrogio, L.2    Annoni, A.3
  • 44
    • 0141519281 scopus 로고    scopus 로고
    • Pathogens target DC-SIGN to influence their fate: DC-SIGN functions as a pathogen receptor with broad specificity
    • DOI 10.1034/j.1600-0463.2003.11107803.x
    • Geijtenbeek TB, Van Kooyk Y (2003) Pathogens target DC-SIGN to Influence their fate DC-SIGN functions as a pathogen receptor with broad specificity. APMIS 111(7-8):698-714 (Pubitemid 37130018)
    • (2003) APMIS , vol.111 , Issue.7-8 , pp. 698-714
    • Geijtenbeek, T.B.H.1    Van Kooyk, Y.2
  • 45
    • 48749085127 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases
    • Gilliet M, Cao W, Liu YJ (2008) Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol 8(8):594-606
    • (2008) Nat Rev Immunol , vol.8 , Issue.8 , pp. 594-606
    • Gilliet, M.1    Cao, W.2    Liu, Y.J.3
  • 46
    • 84864367347 scopus 로고    scopus 로고
    • Manipulating immune tolerance with micro-RNA regulated gene therapy
    • Goudy KS, Annoni A, Naldini L, Roncarolo MG (2011) Manipulating immune tolerance with micro-RNA regulated gene therapy. Front Microbiol 2:221
    • (2011) Front Microbiol , vol.2 , pp. 221
    • Goudy, K.S.1    Annoni, A.2    Naldini, L.3    Roncarolo, M.G.4
  • 47
    • 0041387471 scopus 로고    scopus 로고
    • Heterologous human immunodeficiency virus type 1 lentiviral vectors packaging a simian immunodeficiency virus-derived genome display a specific postentry transduction defect in dendritic cells
    • DOI 10.1128/JVI.77.17.9295-9304.2003
    • Goujon C, Jarrosson-Wuilleme L, Bernaud J, Rigal D, Darlix JL, Cimarelli A (2003) Heterologous human immunodeficiency virus type 1 lentiviral vectors packaging a simian immunodeficiency virus-derived genome display a specific postentry transduction defect in dendritic cells. J Virol 77(17):9295-9304 (Pubitemid 37011026)
    • (2003) Journal of Virology , vol.77 , Issue.17 , pp. 9295-9304
    • Goujon, C.1    Jarrosson-Wuilleme, L.2    Bernaud, J.3    Rigal, D.4    Darlix, J.-L.5    Cimarelli, A.6
  • 50
    • 0032950671 scopus 로고    scopus 로고
    • Depletion in blood CD11c-positive dendritic cells from HIV-infected patients
    • DOI 10.1097/00002030-199905070-00004
    • Grassi F, Hosmalin A, McIlroy D, Calvez V, Debre P, Autran B (1999) Depletion in blood CD11cpositive dendritic cells from HIV-infected patients. AIDS 13(7):759-766 (Pubitemid 29224577)
    • (1999) AIDS , vol.13 , Issue.7 , pp. 759-766
    • Grassi, F.1    Hosmalin, A.2    McIlroy, D.3    Calvez, V.4    Debre, P.5    Autran, B.6
  • 51
    • 0034663035 scopus 로고    scopus 로고
    • Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro
    • Gruber A, Kan-Mitchell J, Kuhen KL, Mukai T, Wong-Staal F (2000) Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIVspecific cytotoxic T-lymphocyte response in vitro. Blood 96(4):1327-1333 (Pubitemid 30658460)
    • (2000) Blood , vol.96 , Issue.4 , pp. 1327-1333
    • Gruber, A.1    Kan-Mitchell, J.2    Kuhen, K.L.3    Mukai, T.4    Wong-Staal, F.5
  • 54
    • 54949104686 scopus 로고    scopus 로고
    • Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adenoassociated virus gene vector: Short-term results of a phase i trial
    • Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, Wang L et al (2008) Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adenoassociated virus gene vector: short-term results of a phase I trial. Hum Gene Ther 19(10):979-990
    • (2008) Hum Gene Ther , vol.19 , Issue.10 , pp. 979-990
    • Hauswirth, W.W.1    Aleman, T.S.2    Kaushal, S.3    Cideciyan, A.V.4    Schwartz, S.B.5    Wang, L.6
  • 56
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, Ganepola S, Mussig A, Allers K et al (2009) Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 360(7):692-698
    • (2009) N Engl J Med , vol.360 , Issue.7 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3    Ganepola, S.4    Mussig, A.5    Allers, K.6
  • 57
    • 77953311689 scopus 로고    scopus 로고
    • Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody
    • Joseph A, Zheng JH, Chen K, Dutta M, Chen C, Stiegler G et al (2010) Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody. J Virol 84(13):6645-6653
    • (2010) J Virol , vol.84 , Issue.13 , pp. 6645-6653
    • Joseph, A.1    Zheng, J.H.2    Chen, K.3    Dutta, M.4    Chen, C.5    Stiegler, G.6
  • 58
    • 23944484509 scopus 로고    scopus 로고
    • Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer
    • DOI 10.1182/blood-2004-11-4358
    • Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL et al (2005) Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood 106(5):1552-1558 (Pubitemid 41208565)
    • (2005) Blood , vol.106 , Issue.5 , pp. 1552-1558
    • Kang, Y.1    Xie, L.2    Tran, D.T.3    Stein, C.S.4    Hickey, M.5    Davidson, B.L.6    McCray Jr., P.B.7
  • 59
    • 34250683023 scopus 로고    scopus 로고
    • Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: An open label, phase I trial
    • DOI 10.1016/S0140-6736(07)60982-9, PII S0140673607609829
    • Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA et al (2007) Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet 369(9579):2097-2105 (Pubitemid 46935946)
    • (2007) Lancet , vol.369 , Issue.9579 , pp. 2097-2105
    • Kaplitt, M.G.1    Feigin, A.2    Tang, C.3    Fitzsimons, H.L.4    Mattis, P.5    Lawlor, P.A.6    Bland, R.J.7    Young, D.8    Strybing, K.9    Eidelberg, D.10    During, M.J.11
  • 60
    • 0037446635 scopus 로고    scopus 로고
    • + T cell proliferation and IL-2 production by highly enriched populations of HIV-infected dendritic cells
    • Kawamura T, Gatanaga H, Borris DL, Connors M, Mitsuya H, Blauvelt A (2003) Decreased stimulation of CD4+ T cell proliferation and IL-2 production by highly enriched populations of HIV-infected dendritic cells. J Immunol 170(8):4260-4266 (Pubitemid 36428193)
    • (2003) Journal of Immunology , vol.170 , Issue.8 , pp. 4260-4266
    • Kawamura, T.1    Gatanaga, H.2    Borris, D.L.3    Connors, M.4    Mitsuya, H.5    Blauvelt, A.6
  • 61
    • 0036136882 scopus 로고    scopus 로고
    • IFN-α secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymus
    • Keir ME, Stoddart CA, Linquist-Stepps V, Moreno ME, McCune JM (2002) IFN-alpha secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymus. J Immunol 168(1):325-331 (Pubitemid 34014133)
    • (2002) Journal of Immunology , vol.168 , Issue.1 , pp. 325-331
    • Keir, M.E.1    Stoddart, C.A.2    Linquist-Stepps, V.3    Moreno, M.E.4    McCune, J.M.5
  • 62
    • 0031985685 scopus 로고    scopus 로고
    • Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1
    • Kim VN, Mitrophanous K, Kingsman SM, Kingsman AJ (1998) Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1. J Virol 72(1):811-816 (Pubitemid 28048905)
    • (1998) Journal of Virology , vol.72 , Issue.1 , pp. 811-816
    • Kim, V.N.1    Mitrophanous, K.2    Kingsman, S.M.3    Kingsman, A.J.4
  • 63
    • 32044462951 scopus 로고    scopus 로고
    • Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects
    • DOI 10.1086/499597
    • Krathwohl MD, Schacker TW, Anderson JL (2006) Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects. J Infect Dis 193(4):494-504 (Pubitemid 43202740)
    • (2006) Journal of Infectious Diseases , vol.193 , Issue.4 , pp. 494-504
    • Krathwohl, M.D.1    Schacker, T.W.2    Anderson, J.L.3
  • 65
    • 0028561948 scopus 로고
    • Transfer of an anti- HIV-1 ribozyme gene into primary human lymphocytes
    • Leavitt MC, Yu M, Yamada O, Kraus G, Looney D, Poeschla E et al (1994) Transfer of an anti- HIV-1 ribozyme gene into primary human lymphocytes. Hum Gene Ther 5(9):1115-1120
    • (1994) Hum Gene Ther , vol.5 , Issue.9 , pp. 1115-1120
    • Leavitt, M.C.1    Yu, M.2    Yamada, O.3    Kraus, G.4    Looney, D.5    Poeschla, E.6
  • 66
    • 80052157712 scopus 로고    scopus 로고
    • Engineered lentiviral vectors pseudotyped with a cd4 receptor and a fusogenic protein can target cells expressing hiv-1 envelope proteins
    • Lee CL, Dang J, Joo KI, Wang P (2011) Engineered lentiviral vectors pseudotyped with a CD4 receptor and a fusogenic protein can target cells expressing HIV-1 envelope proteins. Virus Res 160(1-2):340-350
    • (2011) Virus Res , vol.160 , Issue.1-2 , pp. 340-350
    • Lee, C.L.1    Dang, J.2    Joo, K.I.3    Wang, P.4
  • 67
    • 77955249196 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients
    • Lehmann C, Lafferty M, Garzino-Demo A, Jung N, Hartmann P, Fatkenheuer G et al (2010) Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients. PLoS One 5(6):e11110
    • (2010) PLoS One , vol.5 , Issue.6
    • Lehmann, C.1    Lafferty, M.2    Garzino-Demo, A.3    Jung, N.4    Hartmann, P.5    Fatkenheuer, G.6
  • 69
    • 74149088961 scopus 로고    scopus 로고
    • Activation of transgene-specific T cells following lentivirus-mediated gene delivery to mouse lung
    • Limberis MP, Bell CL, Heath J, Wilson JM (2010) Activation of transgene-specific T cells following lentivirus-mediated gene delivery to mouse lung. Mol Ther 18(1):143-150
    • (2010) Mol Ther , vol.18 , Issue.1 , pp. 143-150
    • Limberis, M.P.1    Bell, C.L.2    Heath, J.3    Wilson, J.M.4
  • 70
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu YJ (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 23:275-306
    • (2005) Annu Rev Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 71
    • 1842636260 scopus 로고    scopus 로고
    • Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells
    • DOI 10.1089/104303404322959542
    • Lizee G, Gonzales MI, Topalian SL (2004) Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells. Hum Gene Ther 15(4):393-404 (Pubitemid 38469781)
    • (2004) Human Gene Therapy , vol.15 , Issue.4 , pp. 393-404
    • Lizee, G.1    Gonzales, M.I.2    Topalian, S.L.3
  • 72
    • 33646343768 scopus 로고    scopus 로고
    • Lentiviral vector expression of tumour antigens in dendritic cells as an immunotherapeutic strategy
    • DOI 10.1007/s00262-005-0095-5
    • Lopes L, Fletcher K, Ikeda Y, Collins M (2006) Lentiviral vector expression of tumour antigens in dendritic cells as an immunotherapeutic strategy. Cancer Immunol Immunother 55(8):1011-1016 (Pubitemid 43673592)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.8 , pp. 1011-1016
    • Lopes, L.1    Fletcher, K.2    Ikeda, Y.3    Collins, M.4
  • 74
    • 70449515073 scopus 로고    scopus 로고
    • Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain
    • Markusic DM, Van Til NP, Hiralall JK, Elferink RP, Seppen J (2009) Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain. BMC Biotechnol 9:85
    • (2009) BMC Biotechnol , vol.9 , pp. 85
    • Markusic, D.M.1    Van Til, N.P.2    Hiralall, J.K.3    Elferink, R.P.4    Seppen, J.5
  • 75
    • 0035802924 scopus 로고    scopus 로고
    • CD4 down modulation on T-cells: An 'immune' checkpoint for HIV
    • DOI 10.1016/S0165-2478(01)00286-3, PII S0165247801002863
    • Marodon G (2001) CD4 down modulation on T-cells: an 'immune' checkpoint for HIV. Immunol Lett 79(3):165-168 (Pubitemid 32971888)
    • (2001) Immunology Letters , vol.79 , Issue.3 , pp. 165-168
    • Marodon, G.1
  • 76
    • 0036310322 scopus 로고    scopus 로고
    • Enhanced presentation of major histocompatibility complex class I-restricted human immunodeficiency virus type 1 (HIV-1) Gag-specific epitopes after DNA immunization with vectors coding for vesicular stomatitis virus glycoprotein-pseudotyped HIV-1 Gag particles
    • DOI 10.1128/JVI.76.15.7544-7553.2002
    • Marsac D, Loirat D, Petit C, Schwartz O, Michel ML (2002) Enhanced presentation of major histocompatibility complex class I-restricted human immunodeficiency virus type 1 (HIV-1) Gagspecific epitopes after DNA immunization with vectors coding for vesicular stomatitis virus glycoprotein-pseudotyped HIV-1 Gag particles. J Virol 76(15):7544-7553 (Pubitemid 34760977)
    • (2002) Journal of Virology , vol.76 , Issue.15 , pp. 7544-7553
    • Marsac, D.1    Loirat, D.2    Petit, C.3    Schwartz, O.4    Michel, M.-L.5
  • 78
    • 79955114567 scopus 로고    scopus 로고
    • Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigenspecific tolerance in mice with low genotoxic risk
    • Matrai J, Cantore A, Bartholomae CC, Annoni A, Wang W, Acosta-Sanchez A et al (2011) Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigenspecific tolerance in mice with low genotoxic risk. Hepatology 53(5):1696-1707
    • (2011) Hepatology , vol.53 , Issue.5 , pp. 1696-1707
    • Matrai, J.1    Cantore, A.2    Bartholomae, C.C.3    Annoni, A.4    Wang, W.5    Acosta-Sanchez, A.6
  • 79
    • 0034692440 scopus 로고    scopus 로고
    • Potent inhibition of human immunodeficiency virus type 1 replication by conditionally replicating human immunodeficiency virus-based lentiviral vectors expressing envelope antisense mRNA
    • Mautino MR, Morgan RA (2000) Potent inhibition of human immunodeficiency virus type 1 replication by conditionally replicating human immunodeficiency virus-based lentiviral vectors expressing envelope antisense mRNA. Hum Gene Ther 11(14):2025-2037
    • (2000) Hum Gene Ther , vol.11 , Issue.14 , pp. 2025-2037
    • Mautino, M.R.1    Morgan, R.A.2
  • 80
    • 0030880814 scopus 로고    scopus 로고
    • A CXCR4/CD4 pseudotype rhabdovirus that selectively infects HIV-1 envelope protein-expressing cells
    • DOI 10.1016/S0092-8674(00)80349-9
    • Mebatsion T, Finke S, Weiland F, Conzelmann KK (1997) A CXCR4/CD4 pseudotype rhabdovirus that selectively infects HIV-1 envelope protein-expressing cells. Cell 90(5):841-847 (Pubitemid 27381623)
    • (1997) Cell , vol.90 , Issue.5 , pp. 841-847
    • Mebatsion, T.1    Finke, S.2    Weiland, F.3    Conzelmann, K.-K.4
  • 81
    • 77954169603 scopus 로고    scopus 로고
    • Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction
    • Meera S, Madhuri T, Manisha G, Ramesh P (2010) Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction. Viral Immunol 23(3):241-249
    • (2010) Viral Immunol , vol.23 , Issue.3 , pp. 241-249
    • Meera, S.1    Madhuri, T.2    Manisha, G.3    Ramesh, P.4
  • 84
    • 0031666744 scopus 로고    scopus 로고
    • Development of a self-inactivating lentivirus vector
    • Miyoshi H, Blomer U, Takahashi M, Gage FH, Verma IM (1998) Development of a self-inactivating lentivirus vector. J Virol 72(10):8150-8157
    • (1998) J Virol , vol.72 , Issue.10 , pp. 8150-8157
    • Miyoshi, H.1    Blomer, U.2    Takahashi, M.3    Gage, F.H.4    Verma, I.M.5
  • 86
    • 65249101260 scopus 로고    scopus 로고
    • The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
    • Montini E, Cesana D, Schmidt M, Sanvito F, Bartholomae CC, Ranzani M et al (2009) The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J Clin Invest 119(4):964-975
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 964-975
    • Montini, E.1    Cesana, D.2    Schmidt, M.3    Sanvito, F.4    Bartholomae, C.C.5    Ranzani, M.6
  • 87
    • 34547152610 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and the quest for transplant tolerance
    • DOI 10.1038/nri2132, PII NRI2132
    • Morelli AE, Thomson AW (2007) Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol 7(8):610-621 (Pubitemid 47123548)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.8 , pp. 610-621
    • Morelli, A.E.1    Thomson, A.W.2
  • 88
    • 3042841635 scopus 로고    scopus 로고
    • Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection
    • DOI 10.2174/1570162043484906
    • Morris KV, Rossi JJ (2004) Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection. Curr HIV Res 2(2):185-191 (Pubitemid 38854930)
    • (2004) Current HIV Research , vol.2 , Issue.2 , pp. 185-191
    • Morris, K.V.1    Rossi, J.J.2
  • 89
    • 3042773732 scopus 로고    scopus 로고
    • Transduction of cell lines and primary cells by FIV-packaged HIV vectors
    • DOI 10.1016/j.ymthe.2004.03.019, PII S1525001604001224
    • Morris KV, Gilbert J, Wong-Staal F, Gasmi M, Looney DJ (2004) Transduction of cell lines and primary cells by FIV-packaged HIV vectors. Mol Ther 10(1):181-190 (Pubitemid 38878160)
    • (2004) Molecular Therapy , vol.10 , Issue.1 , pp. 181-190
    • Morris, K.V.1    Gilbert, J.2    Wong-Staal, F.3    Gasmi, M.4    Looney, D.J.5
  • 90
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH et al (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272(5259):263-267 (Pubitemid 26119138)
    • (1996) Science , vol.272 , Issue.5259 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8
  • 91
    • 0032191380 scopus 로고    scopus 로고
    • Lentiviruses as gene transfer agents for delivery to non-dividing cells
    • DOI 10.1016/S0958-1669(98)80029-3
    • Naldini L (1998) Lentiviruses as gene transfer agents for delivery to non-dividing cells. Curr Opin Biotechnol 9(5):457-463 (Pubitemid 28478965)
    • (1998) Current Opinion in Biotechnology , vol.9 , Issue.5 , pp. 457-463
    • Naldini, L.1
  • 92
    • 77949424429 scopus 로고    scopus 로고
    • Progress and prospects: Immune responses to viral vectors
    • Nayak S, Herzog RW (2010) Progress and prospects: immune responses to viral vectors. Gene Ther 17(3):295-304
    • (2010) Gene Ther , vol.17 , Issue.3 , pp. 295-304
    • Nayak, S.1    Herzog, R.W.2
  • 94
    • 67349216345 scopus 로고    scopus 로고
    • Studies on tolllike receptor stimuli responsiveness in HIV-1 and HIV-2 infections
    • Nowroozalizadeh S, Mansson F, da Silva Z, Repits J, Dabo B, Pereira C et al (2009) Studies on tolllike receptor stimuli responsiveness in HIV-1 and HIV-2 infections. Cytokine 46(3):325-331
    • (2009) Cytokine , vol.46 , Issue.3 , pp. 325-331
    • Nowroozalizadeh, S.1    Mansson, F.2    Da Silva, Z.3    Repits, J.4    Dabo, B.5    Pereira, C.6
  • 95
    • 79851502456 scopus 로고    scopus 로고
    • Leukodystrophy and gene therapy with a dimmer switch
    • Orchard PJ, Wagner JE (2011) Leukodystrophy and gene therapy with a dimmer switch. N Engl J Med 364(6):572-573
    • (2011) N Engl J Med , vol.364 , Issue.6 , pp. 572-573
    • Orchard, P.J.1    Wagner, J.E.2
  • 96
    • 0035892117 scopus 로고    scopus 로고
    • Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection
    • Pacanowski J, Kahi S, Baillet M, Lebon P, Deveau C, Goujard C et al (2001) Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection. Blood 98(10):3016-3021
    • (2001) Blood , vol.98 , Issue.10 , pp. 3016-3021
    • Pacanowski, J.1    Kahi, S.2    Baillet, M.3    Lebon, P.4    Deveau, C.5    Goujard, C.6
  • 97
    • 13444309711 scopus 로고    scopus 로고
    • Liver immunobiology
    • DOI 10.1080/01926230590522365
    • Parker GA, Picut CA (2005) Liver immunobiology. Toxicol Pathol 33(1):52-62 (Pubitemid 40216804)
    • (2005) Toxicologic Pathology , vol.33 , Issue.1 , pp. 52-62
    • Parker, G.A.1    Picut, C.A.2
  • 98
    • 20444406490 scopus 로고    scopus 로고
    • Human BDCA-1-positive blood dendritic cells differentiate into phenotypically distinct immature and mature populations in the absence of exogenous maturational stimuli: Differentiation failure in HIV infection
    • Patterson S, Donaghy H, Amjadi P, Gazzard B, Gotch F, Kelleher P (2005) Human BDCA-1- positive blood dendritic cells differentiate into phenotypically distinct immature and mature populations in the absence of exogenous maturational stimuli: differentiation failure in HIV infection. J Immunol 174(12):8200-8209 (Pubitemid 40806332)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 8200-8209
    • Patterson, S.1    Donaghy, H.2    Amjadi, P.3    Gazzard, B.4    Gotch, F.5    Kelleher, P.6
  • 99
    • 30844469306 scopus 로고    scopus 로고
    • Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles
    • DOI 10.1016/j.virol.2005.09.054, PII S0042682205006276
    • Peretti S, Schiavoni I, Pugliese K, Federico M (2006) Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles. Virology 345(1):115-126 (Pubitemid 43107577)
    • (2006) Virology , vol.345 , Issue.1 , pp. 115-126
    • Peretti, S.1    Schiavoni, I.2    Pugliese, K.3    Federico, M.4
  • 100
    • 33846081072 scopus 로고    scopus 로고
    • Tubulovesicular structures within Vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via toll-like receptor 9
    • DOI 10.1128/JVI.01818-06
    • Pichlmair A, Diebold SS, Gschmeissner S, Takeuchi Y, Ikeda Y, Collins MK et al (2007) Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9. J Virol 81(2):539-547 (Pubitemid 46067881)
    • (2007) Journal of Virology , vol.81 , Issue.2 , pp. 539-547
    • Pichlmair, A.1    Diebold, S.S.2    Gschmeissner, S.3    Takeuchi, Y.4    Ikeda, Y.5    Collins, M.K.6    Reis E Sousa, C.7
  • 101
    • 82655183583 scopus 로고    scopus 로고
    • Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy
    • Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum CJ, Chougnet CA (2011) Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS One 6(12):e28118
    • (2011) PLoS One , vol.6 , Issue.12
    • Presicce, P.1    Orsborn, K.2    King, E.3    Pratt, J.4    Fichtenbaum, C.J.5    Chougnet, C.A.6
  • 104
    • 79951840580 scopus 로고    scopus 로고
    • HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells
    • Rossetti M, Gregori S, Hauben E, Brown BD, Sergi LS, Naldini L et al (2011) HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells. Hum Gene Ther 22(2):177-188
    • (2011) Hum Gene Ther , vol.22 , Issue.2 , pp. 177-188
    • Rossetti, M.1    Gregori, S.2    Hauben, E.3    Brown, B.D.4    Sergi, L.S.5    Naldini, L.6
  • 105
    • 0036708227 scopus 로고    scopus 로고
    • Lentiviral-mediated gene delivery in human monocyte-derived dendritic cells: Optimized design and procedures for highly efficient transduction compatible with clinical constraints
    • DOI 10.1038/sj.cgt.7700500
    • Rouas R, Uch R, Cleuter Y, Jordier F, Bagnis C, Mannoni P et al (2002) Lentiviral-mediated gene delivery in human monocyte-derived dendritic cells: optimized design and procedures for highly Efficient transduction compatible with clinical constraints. Cancer Gene Ther 9(9): 715-724 (Pubitemid 34971302)
    • (2002) Cancer Gene Therapy , vol.9 , Issue.9 , pp. 715-724
    • Rouas, R.1    Uch, R.2    Cleuter, Y.3    Jordier, F.4    Bagnis, C.5    Mannoni, P.6    Lewalle, P.7    Martiat, P.8    Van Den Broeke, A.9
  • 106
    • 30344475525 scopus 로고    scopus 로고
    • Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene
    • DOI 10.1016/j.ymthe.2005.08.025, PII S1525001605016187
    • Rowe HM, Lopes L, Ikeda Y, Bailey R, Barde I, Zenke M et al (2006) Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene. Mol Ther 13(2):310-319 (Pubitemid 43056896)
    • (2006) Molecular Therapy , vol.13 , Issue.2 , pp. 310-319
    • Rowe, H.M.1    Lopes, L.2    Ikeda, Y.3    Bailey, R.4    Barde, I.5    Zenke, M.6    Chain, B.M.7    Collins, M.K.8
  • 107
    • 78149442321 scopus 로고    scopus 로고
    • Evidence of dysregulation of dendritic cells in primary HIV infection
    • Sabado RL, O'Brien M, Subedi A, Qin L, Hu N, Taylor E et al (2010) Evidence of dysregulation of dendritic cells in primary HIV infection. Blood 116(19):3839-3852
    • (2010) Blood , vol.116 , Issue.19 , pp. 3839-3852
    • Sabado, R.L.1    O'Brien, M.2    Subedi, A.3    Qin, L.4    Hu, N.5    Taylor, E.6
  • 108
    • 0035404586 scopus 로고    scopus 로고
    • Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells
    • DOI 10.1002/1521-2254(200107/08)3:4 <311::AID-JGM198>3.0.CO;2-B
    • Salmon P, Arrighi JF, Piguet V, Chapuis B, Zubler RH, Trono D et al (2001) Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgeneexpressing immature and mature dendritic cells. J Gene Med 3(4):311-320 (Pubitemid 33691770)
    • (2001) Journal of Gene Medicine , vol.3 , Issue.4 , pp. 311-320
    • Salmon, P.1    Arrighi, J.-F.2    Piguet, V.3    Chapuis, B.4    Zubler, R.H.5    Trono, D.6    Kindler, V.7
  • 109
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • DOI 10.1016/S0092-8674(02)00864-4
    • Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F (2002) HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110(4):521-529 (Pubitemid 35232295)
    • (2002) Cell , vol.110 , Issue.4 , pp. 521-529
    • Schroder, A.R.W.1    Shinn, P.2    Chen, H.3    Berry, C.4    Ecker, J.R.5    Bushman, F.6
  • 110
    • 0034135980 scopus 로고    scopus 로고
    • Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system
    • Schroers R, Sinha I, Segall H, Schmidt-Wolf IG, Rooney CM, Brenner MK et al (2000) Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system. Mol Ther 1(2):171-179
    • (2000) Mol Ther , vol.1 , Issue.2 , pp. 171-179
    • Schroers, R.1    Sinha, I.2    Segall, H.3    Schmidt-Wolf, I.G.4    Rooney, C.M.5    Brenner, M.K.6
  • 111
    • 85047692244 scopus 로고    scopus 로고
    • Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
    • DOI 10.1172/JCI200420243
    • Sevilla N, McGavern DB, Teng C, Kunz S, Oldstone MB (2004) Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion. J Clin Invest 113(5):737-745 (Pubitemid 38544167)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.5 , pp. 737-745
    • Sevilla, N.1    McGavern, D.B.2    Teng, C.3    Kunz, S.4    Oldstone, M.B.A.5
  • 112
    • 77949885010 scopus 로고    scopus 로고
    • A highly Efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
    • Shimizu S, Hong P, Arumugam B, Pokomo L, Boyer J, Koizumi N et al (2010) A highly Efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood 115(8):1534-1544
    • (2010) Blood , vol.115 , Issue.8 , pp. 1534-1544
    • Shimizu, S.1    Hong, P.2    Arumugam, B.3    Pokomo, L.4    Boyer, J.5    Koizumi, N.6
  • 113
    • 26444589094 scopus 로고    scopus 로고
    • Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer
    • DOI 10.1128/JVI.79.20.12818-12827.2005
    • Sinn PL, Burnight ER, Hickey MA, Blissard GW, McCray PB Jr (2005) Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer. J Virol 79(20):12818-12827 (Pubitemid 41433201)
    • (2005) Journal of Virology , vol.79 , Issue.20 , pp. 12818-12827
    • Sinn, P.L.1    Burnight, E.R.2    Hickey, M.A.3    Blissard, G.W.4    McCray Jr., P.B.5
  • 115
    • 0034672356 scopus 로고    scopus 로고
    • The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
    • Sirven A, P fl umio F, Zennou V, Titeux M, Vainchenker W, Coulombel L et al (2000) The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. Blood 96(13): 4103-4110
    • (2000) Blood , vol.96 , Issue.13 , pp. 4103-4110
    • Sirven, A.P.1    Fl Umio, F.2    Zennou, V.3    Titeux, M.4    Vainchenker, W.5    Coulombel, L.6
  • 116
    • 7244240713 scopus 로고    scopus 로고
    • HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation
    • DOI 10.1182/blood-2003-07-2314
    • Smed-Sorensen A, Lore K, Walther-Jallow L, Andersson J, Spetz AL (2004) HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation. Blood 104(9):2810-2817 (Pubitemid 39434966)
    • (2004) Blood , vol.104 , Issue.9 , pp. 2810-2817
    • Smed-Sorensen, A.1    Lore, K.2    Walther-Jallow, L.3    Andersson, J.4    Spetz, A.-L.5
  • 117
    • 21644483118 scopus 로고    scopus 로고
    • Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells
    • DOI 10.1128/JVI.79.14.8861-8869.2005
    • Smed-Sorensen A, Lore K, VasudeVan J, Louder MK, Andersson J, Mascola JR et al (2005) Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells. J Virol 79(14):8861-8869 (Pubitemid 40934796)
    • (2005) Journal of Virology , vol.79 , Issue.14 , pp. 8861-8869
    • Smed-Sorensen, A.1    Lore, K.2    VasudeVan, J.3    Louder, M.K.4    Andersson, J.5    Mascola, J.R.6    Spetz, A.-L.7    Koup, R.A.8
  • 118
    • 0035883082 scopus 로고    scopus 로고
    • Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients
    • Soumelis V, Scott I, Gheyas F, Bouhour D, Cozon G, Cotte L et al (2001) Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood 98(4):906-912
    • (2001) Blood , vol.98 , Issue.4 , pp. 906-912
    • Soumelis, V.1    Scott, I.2    Gheyas, F.3    Bouhour, D.4    Cozon, G.5    Cotte, L.6
  • 120
    • 0025350783 scopus 로고
    • Integration is not necessary for expression of human immunodeficiency virus type 1 protein products
    • Stevenson M, Haggerty S, Lamonica CA, Meier CM, Welch SK, Wasiak AJ (1990) Integration is not necessary for expression of human immunodeficiency virus type 1 protein products. J Virol 64(5):2421-2425 (Pubitemid 20148495)
    • (1990) Journal of Virology , vol.64 , Issue.5 , pp. 2421-2425
    • Stevenson, M.1    Haggerty, S.2    Lamonica, C.A.3    Meier, C.M.4    Welch, S.-K.5    Wasiak, A.J.6
  • 121
    • 0029120442 scopus 로고
    • Target sequence-specific inhibition of HIV-1 replication by ribozymes directed to tat RNA
    • Sun LQ, Wang L, Gerlach WL, Symonds G (1995) Target sequence-specific inhibition of HIV-1 replication by ribozymes directed to tat RNA. Nucleic Acids Res 23(15):2909-2913
    • (1995) Nucleic Acids Res , vol.23 , Issue.15 , pp. 2909-2913
    • Sun, L.Q.1    Wang, L.2    Gerlach, W.L.3    Symonds, G.4
  • 126
    • 33747863620 scopus 로고    scopus 로고
    • +- derived Langerhans cells with lentiviral vectors in the absence of phenotypic and functional maturation
    • DOI 10.1002/jgm.923
    • Veron P, Boutin S, Bernard J, Danos O, Davoust J, Masurier C (2006) Efficient transduction of monocyte- and CD34+-derived Langerhans cells with lentiviral vectors in the absence of phenotypic and functional maturation. J Gene Med 8(8):951-961 (Pubitemid 44282991)
    • (2006) Journal of Gene Medicine , vol.8 , Issue.8 , pp. 951-961
    • Veron, P.1    Boutin, S.2    Bernard, J.3    Danos, O.4    Davoust, J.5    Masurier, C.6
  • 127
    • 0034278156 scopus 로고    scopus 로고
    • Lentiviral vectors: Excellent tools for experimental gene transfer and promising candidates for gene therapy
    • Vigna E, Naldini L (2000) Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy. J Gene Med 2(5):308-316
    • (2000) J Gene Med , vol.2 , Issue.5 , pp. 308-316
    • Vigna, E.1    Naldini, L.2
  • 128
    • 13844320402 scopus 로고    scopus 로고
    • HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
    • DOI 10.1093/nar/gki220
    • Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B (2005) HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res 33(2):796-804 (Pubitemid 40361009)
    • (2005) Nucleic Acids Research , vol.33 , Issue.2 , pp. 796-804
    • Westerhout, E.M.1    Ooms, M.2    Vink, M.3    Das, A.T.4    Berkhout, B.5
  • 130
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • DOI 10.1126/science.1083413
    • Wu X, Li Y, Crise B, Burgess SM (2003) Transcription start regions in the human genome are favored targets for MLV integration. Science 300(5626):1749-1751 (Pubitemid 36712571)
    • (2003) Science , vol.300 , Issue.5626 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 132
    • 29944431988 scopus 로고    scopus 로고
    • Targeted infection of HIV-1 Env expressing cells by HIV(CD4/CXCR4) vectors reveals a potential new rationale for HIV-1 mediated down-modulation of CD4
    • Ye Z, Harmison GG, Ragheb JA, Schubert M (2005) Targeted infection of HIV-1 Env expressing cells by HIV(CD4/CXCR4) vectors reveals a potential new rationale for HIV-1 mediated down-modulation of CD4. Retrovirology 2:80
    • (2005) Retrovirology , vol.2 , pp. 80
    • Ye, Z.1    Harmison, G.G.2    Ragheb, J.A.3    Schubert, M.4
  • 133
    • 80052379842 scopus 로고    scopus 로고
    • Systemic immune activation in HIV infection is associated with decreased MDC responsiveness to TLR ligand and inability to activate naive CD4 T-cells
    • Yonkers NL, Rodriguez B, Asaad R, Lederman MM, Anthony DD (2011) Systemic immune activation in HIV infection is associated with decreased MDC responsiveness to TLR ligand and inability to activate naive CD4 T-cells. PLoS One 6(9):e23884
    • (2011) PLoS One , vol.6 , Issue.9
    • Yonkers, N.L.1    Rodriguez, B.2    Asaad, R.3    Lederman, M.M.4    Anthony, D.D.5
  • 134
    • 0034646513 scopus 로고    scopus 로고
    • HIV-1 genome nuclear import is mediated by a central DNA flap
    • DOI 10.1016/S0092-8674(00)80828-4
    • Zennou V, Petit C, Guetard D, Nerhbass U, Montagnier L, Charneau P (2000) HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 101(2):173-185 (Pubitemid 32004745)
    • (2000) Cell , vol.101 , Issue.2 , pp. 173-185
    • Zennou, V.1    Petit, C.2    Guetard, D.3    Nerhbass, U.4    Montagnier, L.5    Charneau, P.6
  • 135
    • 0027973382 scopus 로고
    • Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes
    • DOI 10.1016/0378-1119(94)90409-X
    • Zhou C, Bahner IC, Larson GP, Zaia JA, Rossi JJ, Kohn EB (1994) Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes. Gene 149(1):33-39 (Pubitemid 24347697)
    • (1994) Gene , vol.149 , Issue.1 , pp. 33-39
    • Zhou, C.1    Bahner, I.C.2    Larson, G.P.3    Zaia, J.A.4    Rossi, J.J.5    Kohn, D.B.6
  • 136
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves Efficient gene delivery in vivo
    • Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D (1997) Multiply attenuated lentiviral vector achieves Efficient gene delivery in vivo. Nat Biotechnol 15(9):871-875
    • (1997) Nat Biotechnol , vol.15 , Issue.9 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 138
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R, Donello JE, Trono D, Hope TJ (1999) Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 73(4):2886-2892 (Pubitemid 29135675)
    • (1999) Journal of Virology , vol.73 , Issue.4 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4


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