Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes

Science

Volumn 278, Issue 5342, 1997, Pages 1462-1464

  Endres, Michael J ^a   Jaffer, Salman ^a   Haggarty, Beth ^a   Turner, Julie D ^a   Doranz, Benjamin J ^a   O'Brien, Peter J ^a   Kolson, Dennis L ^a   Hoxie, James A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; QUAIL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS ENVELOPE; VIRUS GENE;

ANIMALS; ANTIGENS, CD4; CELL LINE; GENE PRODUCTS, ENV; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIV-1; HUMANS; MACROPHAGES; PLASMIDS; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR4; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSFECTION;

EID: 0030664181     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5342.1462     Document Type: Article

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26. This work is dedicated to the memory of B. J. Endres. We thank P. Endres, L. Brass, M. Gardner, and M. Nathanson for support and encouragement; T. Keler, N. Yeilding, A. Tehranian, N. Leung, and M. Hitchcock for helpful discussions; N. Landau, R. Doms, D. Gabuzda, R. Collman, I. Verma, G. Cohen, F. Gonzalez-Scarano, V. Planelles, and P. Luciw for generously providing reagents; and J. Romano for expert technical assistance. M.J.E. was supported with a postdoctoral fellowship (NIH HL 07439). B.J.D. was supported with a predoctoral fellowship (Howard Hughes Medical Institute). Additional work was supported by grants to J.A.H. (AI33854 and AI40880) and D.L.K. (R29 NS35007). J.A.H. is a fellow of Cater-Wallace, Inc.