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Volumn 172, Issue 12, 2004, Pages 7832-7840

Defective dendritic cell function in HIV-infected patients receiving effective highly active antiretroviral therapy: Neutralization of IL-10 production and depletion of CD4+CD25+ T cells restore high levels of HIV-specific CD4+ T cell responses induced by dendritic cells generated in the presence of IFN-α

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ANTIGEN P24; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; DIDANOSINE; EFAVIRENZ; INDINAVIR; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; RECOMBINANT ALPHA2B INTERFERON; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 4; RITONAVIR; STAVUDINE; TUBERCULIN; ZIDOVUDINE;

EID: 2942620287     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.12.7832     Document Type: Article
Times cited : (47)

References (55)
  • 4
    • 0032482274 scopus 로고    scopus 로고
    • Immunology: License to kill
    • Lanzavecchia, A. 1998. Immunology: license to kill. Nature 393:413.
    • (1998) Nature , vol.393 , pp. 413
    • Lanzavecchia, A.1
  • 14
    • 0029870407 scopus 로고    scopus 로고
    • Modulation of T cell responses to recall antigens presented by Langerhans cells in HIV-discordant identical twins by anti-interleukin (IL)-10 antibodies and IL-12
    • Blauvelt, A., C. Chougnet, G. M. Shearer, and S. I. Katz. 1996. Modulation of T cell responses to recall antigens presented by Langerhans cells in HIV-discordant identical twins by anti-interleukin (IL)-10 antibodies and IL-12. J. Clin. Invest. 97:1550.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1550
    • Blauvelt, A.1    Chougnet, C.2    Shearer, G.M.3    Katz, S.I.4
  • 15
    • 0033179535 scopus 로고    scopus 로고
    • Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: Implications for immunotherapy
    • Chougnet, C., S. S. Cohen, T. Kawamura, A. L. Landay, H. A. Kessler, E. Thomas, A. Blauvelt, and G. M. Shearer. 1999. Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: implications for immunotherapy. J. Immunol. 163:1666.
    • (1999) J. Immunol. , vol.163 , pp. 1666
    • Chougnet, C.1    Cohen, S.S.2    Kawamura, T.3    Landay, A.L.4    Kessler, H.A.5    Thomas, E.6    Blauvelt, A.7    Shearer, G.M.8
  • 16
    • 0031573052 scopus 로고    scopus 로고
    • Cultured blood dendritic cells retain HIV-1 antigen-presenting capacity for memory CTL during progressive HIV-1 infection
    • Fan, Z., X. L. Huang, L. Zheng, C. Wilson, L. Borowski, J. Liebmann, P. Gupta, J. Margolick, and C. Rinaldo. 1997. Cultured blood dendritic cells retain HIV-1 antigen-presenting capacity for memory CTL during progressive HIV-1 infection. J. Immunol. 159:4973.
    • (1997) J. Immunol. , vol.159 , pp. 4973
    • Fan, Z.1    Huang, X.L.2    Zheng, L.3    Wilson, C.4    Borowski, L.5    Liebmann, J.6    Gupta, P.7    Margolick, J.8    Rinaldo, C.9
  • 17
    • 0026608067 scopus 로고
    • Antigen-presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection
    • Macatonia, S. E., M. Gompels, A. J. Pinching, S. Patterson, and S. C. Knight. 1992. Antigen-presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection. Immunology 75:576.
    • (1992) Immunology , vol.75 , pp. 576
    • Macatonia, S.E.1    Gompels, M.2    Pinching, A.J.3    Patterson, S.4    Knight, S.C.5
  • 18
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1
    • Donaghy, H., B. Gazzard, F. Gotch, and S. Patterson. 2003. Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1. Blood 101:4505.
    • (2003) Blood , vol.101 , pp. 4505
    • Donaghy, H.1    Gazzard, B.2    Gotch, F.3    Patterson, S.4
  • 20
    • 0033935467 scopus 로고    scopus 로고
    • ++ cells derived in vitro from peripheral blood monocytes exhibit phenotypic and functional dendritic cell-like characteristics
    • ++ cells derived in vitro from peripheral blood monocytes exhibit phenotypic and functional dendritic cell-like characteristics. Eur. J. Immunol. 30:1872.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1872
    • Ancuta, P.1    Weiss, L.2    Haeffner-Cavaillon, N.3
  • 22
    • 0035751104 scopus 로고    scopus 로고
    • HIV-1 Tat protein induces IL-10 production by human monocytes: Implications of the PKC and calcium pathway
    • Yamina, B., C. Xavier, M. Marc, L. Catherine, B. Abdallah, and E. Bahraoui. 2001. HIV-1 Tat protein induces IL-10 production by human monocytes: implications of the PKC and calcium pathway. J. Soc. Biol. 195:319.
    • (2001) J. Soc. Biol. , vol.195 , pp. 319
    • Yamina, B.1    Xavier, C.2    Marc, M.3    Catherine, L.4    Abdallah, B.5    Bahraoui, E.6
  • 23
    • 0033790254 scopus 로고    scopus 로고
    • Monocytes are target cells for IL-10 induction by HIV-1 Nef protein
    • Tangsinmankong, N., N. K. Day, R. A. Good, and S. Haraguchi. 2000. Monocytes are target cells for IL-10 induction by HIV-1 Nef protein. Cytokine 12:1506.
    • (2000) Cytokine , vol.12 , pp. 1506
    • Tangsinmankong, N.1    Day, N.K.2    Good, R.A.3    Haraguchi, S.4
  • 24
    • 0031013905 scopus 로고    scopus 로고
    • Split activity of interleukin-10 on antigen capture and antigen presentation by human dendritic cells: Definition of a maturative step
    • Morel, A. S., S. Quaratino, D. C. Douek, and M. Londei. 1997. Split activity of interleukin-10 on antigen capture and antigen presentation by human dendritic cells: definition of a maturative step. Eur. J. Immunol. 27:26.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 26
    • Morel, A.S.1    Quaratino, S.2    Douek, D.C.3    Londei, M.4
  • 28
    • 0035890108 scopus 로고    scopus 로고
    • + T cell immunity to gag in HIV-1-infected individuals with differential disease progression: Reciprocal interferon-γ and interleukin-10 responses
    • + T cell immunity to gag in HIV-1-infected individuals with differential disease progression: reciprocal interferon-γ and interleukin-10 responses. J. Infect. Dis. 184:1268.
    • (2001) J. Infect. Dis. , vol.184 , pp. 1268
    • Ostrowski, M.A.1    Gu, J.X.2    Kovacs, C.3    Freedman, J.4    Luscher, M.A.5    MacDonald, K.S.6
  • 31
    • 0028791730 scopus 로고
    • Dysregulated production of interleukin-10 (IL-10) and IL-12 by peripheral blood lymphocytes from human immunodeficiency virus-infected individuals is associated with altered proliferative responses to recall antigens
    • Daftarian, M. P., F. Diaz-Mitoma, W. D. Creery, W. Cameron, and A. Kumar. 1995. Dysregulated production of interleukin-10 (IL-10) and IL-12 by peripheral blood lymphocytes from human immunodeficiency virus-infected individuals is associated with altered proliferative responses to recall antigens. Clin. Diagn. Lab. Immunol. 2:712.
    • (1995) Clin. Diagn. Lab. Immunol. , vol.2 , pp. 712
    • Daftarian, M.P.1    Diaz-Mitoma, F.2    Creery, W.D.3    Cameron, W.4    Kumar, A.5
  • 32
    • 0033766287 scopus 로고    scopus 로고
    • Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: Implication of protein kinase C-dependent pathway
    • Badou, A., Y. Bennasser, M. Moreau, C. Leclerc, M. Benkirane, and E. Bahraoui. 2000. Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway. J. Virol. 74:10551.
    • (2000) J. Virol. , vol.74 , pp. 10551
    • Badou, A.1    Bennasser, Y.2    Moreau, M.3    Leclerc, C.4    Benkirane, M.5    Bahraoui, E.6
  • 33
    • 0030908348 scopus 로고    scopus 로고
    • Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway
    • Brigino, E., S. Haraguchi, A. Koutsonikolis, G. J. Cianciolo, U. Owens, R. A. Good, and N. K. Day. 1997. Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway. Proc. Natl. Acad. Sci. USA 94:3178.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3178
    • Brigino, E.1    Haraguchi, S.2    Koutsonikolis, A.3    Cianciolo, G.J.4    Owens, U.5    Good, R.A.6    Day, N.K.7
  • 34
    • 0030903990 scopus 로고    scopus 로고
    • HIV-1 recombinant gp41 induces IL-10 expression and production in peripheral blood monocytes but not in T-lymphocytes
    • Koutsonikolis, A., S. Haraguchi, E. N. Brigino, U. E. Owens, R. A. Good, and N. K. Day. 1997. HIV-1 recombinant gp41 induces IL-10 expression and production in peripheral blood monocytes but not in T-lymphocytes. Immunol. Lett. 55:109.
    • (1997) Immunol. Lett. , vol.55 , pp. 109
    • Koutsonikolis, A.1    Haraguchi, S.2    Brigino, E.N.3    Owens, U.E.4    Good, R.A.5    Day, N.K.6
  • 35
    • 0032955893 scopus 로고    scopus 로고
    • IL-10 in HIV infection: Increasing serum IL-10 levels with disease progression-down-regulatory effect of potent anti-retroviral therapy
    • Stylianou, E., P. Aukrust, D. Kvale, F. Muller, and S. S. Froland. 1999. IL-10 in HIV infection: increasing serum IL-10 levels with disease progression-down-regulatory effect of potent anti-retroviral therapy. Clin. Exp. Immunol. 116:115.
    • (1999) Clin. Exp. Immunol. , vol.116 , pp. 115
    • Stylianou, E.1    Aukrust, P.2    Kvale, D.3    Muller, F.4    Froland, S.S.5
  • 40
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
    • (1998) Nature , vol.392 , pp. 245
    • Banchereau, J.1    Steinman, R.M.2
  • 42
    • 0033104946 scopus 로고    scopus 로고
    • Interleukin-10 inhibits expression of both interferon α- and interferon γ-induced genes by suppressing tyrosine phosphorylation of STAT1
    • Ito, S., P. Ansari, M. Sakatsume, H. Dickensheets, N. Vazquez, R. P. Donnelly, A. C. Larner, and D. S. Finbloom. 1999. Interleukin-10 inhibits expression of both interferon α- and interferon γ-induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 93:1456.
    • (1999) Blood , vol.93 , pp. 1456
    • Ito, S.1    Ansari, P.2    Sakatsume, M.3    Dickensheets, H.4    Vazquez, N.5    Donnelly, R.P.6    Larner, A.C.7    Finbloom, D.S.8
  • 43
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Gougeon, M. L. 2003. Apoptosis as an HIV strategy to escape immune attack. Nat. Rev. Immunol. 3:392.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 392
    • Gougeon, M.L.1
  • 45
    • 0036284386 scopus 로고    scopus 로고
    • Regulation of major histocompatibility complex class II synthesis by interleukin-10
    • Morel, A. S., G. Coulton, and M. Londei. 2002. Regulation of major histocompatibility complex class II synthesis by interleukin-10. Immunology 106:229.
    • (2002) Immunology , vol.106 , pp. 229
    • Morel, A.S.1    Coulton, G.2    Londei, M.3
  • 46
    • 0032988870 scopus 로고    scopus 로고
    • - T cells of human immunodeficiency virus-infected individuals: Effects of interleukin-15 and comparison with interleukin-2
    • - T cells of human immunodeficiency virus-infected individuals: effects of interleukin-15 and comparison with interleukin-2. Immunology 97:181.
    • (1999) Immunology , vol.97 , pp. 181
    • Naora, H.1    Gougeon, M.2
  • 47
    • 0034658658 scopus 로고    scopus 로고
    • Type 1 interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice
    • Santini, S. M., C. Lapenta, M. Logozzi, S. Parlato, M. Spada, T. Di Pucchio, and F. Belardelli. 2000. Type 1 interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J. Exp. Med. 191:1777.
    • (2000) J. Exp. Med. , vol.191 , pp. 1777
    • Santini, S.M.1    Lapenta, C.2    Logozzi, M.3    Parlato, S.4    Spada, M.5    Di Pucchio, T.6    Belardelli, F.7
  • 50
    • 0037436193 scopus 로고    scopus 로고
    • Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: A randomized controlled trial
    • Levy, Y., C. Durier, R. Krzysiek, C. Rabian, C. Capitant, A. S. Lascaux, C. Michon, E. Oksenhendler, L. Weiss, J. A. Gastaut, et al. 2003. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: a randomized controlled trial. AIDS 17:343.
    • (2003) AIDS , vol.17 , pp. 343
    • Levy, Y.1    Durier, C.2    Krzysiek, R.3    Rabian, C.4    Capitant, C.5    Lascaux, A.S.6    Michon, C.7    Oksenhendler, E.8    Weiss, L.9    Gastaut, J.A.10
  • 53
    • 0042662852 scopus 로고    scopus 로고
    • Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-α
    • Lapenta, C., S. M. Santini, M. Logozzi, M. Spada, M. Andreotti, T. Di Pucchio, S. Parlato, and F. Belardelli. 2003. Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-α. J. Exp. Med. 198:361.
    • (2003) J. Exp. Med. , vol.198 , pp. 361
    • Lapenta, C.1    Santini, S.M.2    Logozzi, M.3    Spada, M.4    Andreotti, M.5    Di Pucchio, T.6    Parlato, S.7    Belardelli, F.8
  • 55
    • 85088004512 scopus 로고    scopus 로고
    • + T-cell proliferation: Modulation by autocrine IL-10, enhanced T-cell apoptosis and T regulatory type 1 cells
    • In press
    • + T-cell proliferation: modulation by autocrine IL-10, enhanced T-cell apoptosis and T regulatory type 1 cells. Int. Immunol. In press.
    • Int. Immunol.
    • Carbonneil, C.1    Saidi, H.2    Donkova-Petrini, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.