메뉴 건너뛰기




Volumn 6, Issue 9, 2011, Pages

Systemic immune activation in HIV infection is associated with decreased MDC responsiveness to TLR ligand and inability to activate naive CD4 T-cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD83 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 6; POLYINOSINIC POLYCYTIDYLIC ACID; T LYMPHOCYTE RECEPTOR; LIGAND; TOLL LIKE RECEPTOR;

EID: 80052379842     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023884     Document Type: Article
Times cited : (24)

References (50)
  • 1
    • 0030861967 scopus 로고    scopus 로고
    • Response to Hepatitis A Vaccination in Human Immunodeficiency Virus-Infected and -Uninfected Homosexual Men
    • Neilsen GA, Bodsworth NJ, Watts N, (1997) Response to Hepatitis A Vaccination in Human Immunodeficiency Virus-Infected and-Uninfected Homosexual Men. The Journal of Infectious Diseases 176: 1064-1067.
    • (1997) The Journal of Infectious Diseases , vol.176 , pp. 1064-1067
    • Neilsen, G.A.1    Bodsworth, N.J.2    Watts, N.3
  • 2
    • 27644490225 scopus 로고    scopus 로고
    • Hepatitis A and B immunizations of individuals infected with human immunodeficiency virus
    • Laurence JC, (2005) Hepatitis A and B immunizations of individuals infected with human immunodeficiency virus. The American Journal of Medicine 118: 75-83.
    • (2005) The American Journal of Medicine , vol.118 , pp. 75-83
    • Laurence, J.C.1
  • 3
    • 0033030988 scopus 로고    scopus 로고
    • Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection
    • Hay CM, Ruhl DJ, Basgoz NO, Wilson CC, Billingsley JM, et al. (1999) Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection. J Virol 73: 5509-5519.
    • (1999) J Virol , vol.73 , pp. 5509-5519
    • Hay, C.M.1    Ruhl, D.J.2    Basgoz, N.O.3    Wilson, C.C.4    Billingsley, J.M.5
  • 4
    • 0034743924 scopus 로고    scopus 로고
    • Human immunodeficiency virus pathogenesis and prospects for immune control in patients with established infection
    • Cohen DE, Walker BD, (2001) Human immunodeficiency virus pathogenesis and prospects for immune control in patients with established infection. Clin Infect Dis 32: 1756-1768.
    • (2001) Clin Infect Dis , vol.32 , pp. 1756-1768
    • Cohen, D.E.1    Walker, B.D.2
  • 5
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, et al. (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 12: 1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3    Asher, T.E.4    Silvestri, G.5
  • 6
    • 34547130280 scopus 로고    scopus 로고
    • MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands
    • Meier A, Alter G, Frahm N, Sidhu H, Li B, et al. (2007) MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands. J Virol 81: 8180-8191.
    • (2007) J Virol , vol.81 , pp. 8180-8191
    • Meier, A.1    Alter, G.2    Frahm, N.3    Sidhu, H.4    Li, B.5
  • 7
    • 58849119199 scopus 로고    scopus 로고
    • Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology
    • Baenziger S, Heikenwalder M, Johansen P, Schlaepfer E, Hofer U, et al. (2009) Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood 113: 377-388.
    • (2009) Blood , vol.113 , pp. 377-388
    • Baenziger, S.1    Heikenwalder, M.2    Johansen, P.3    Schlaepfer, E.4    Hofer, U.5
  • 8
    • 0033582629 scopus 로고    scopus 로고
    • Reciprocal control of T helper cell and dendritic cell differentiation
    • Rissoan MC, Soumelis V, Kadowaki N, Grouard G, Briere F, et al. (1999) Reciprocal control of T helper cell and dendritic cell differentiation. Science 283: 1183-1186.
    • (1999) Science , vol.283 , pp. 1183-1186
    • Rissoan, M.C.1    Soumelis, V.2    Kadowaki, N.3    Grouard, G.4    Briere, F.5
  • 9
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
    • Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, et al. (2002) Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides. J Immunol 168: 4531-4537.
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5
  • 10
    • 0035179882 scopus 로고    scopus 로고
    • Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
    • Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A, (2001) Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. European Journal of Immunology 31: 3388-3393.
    • (2001) European Journal of Immunology , vol.31 , pp. 3388-3393
    • Jarrossay, D.1    Napolitani, G.2    Colonna, M.3    Sallusto, F.4    Lanzavecchia, A.5
  • 11
    • 0141923686 scopus 로고    scopus 로고
    • Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
    • Lore K, Betts MR, Brenchley JM, Kuruppu J, Khojasteh S, et al. (2003) Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses. J Immunol 171: 4320-4328.
    • (2003) J Immunol , vol.171 , pp. 4320-4328
    • Lore, K.1    Betts, M.R.2    Brenchley, J.M.3    Kuruppu, J.4    Khojasteh, S.5
  • 12
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R, (2004) Toll-like receptor control of the adaptive immune responses. Nat Immunol 5: 987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 13
    • 0035178909 scopus 로고    scopus 로고
    • Decreased interferon-alpha production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors
    • Feldman S, Stein D, Amrute S, Denny T, Garcia Z, et al. (2001) Decreased interferon-alpha production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors. Clin Immunol 101: 201-210.
    • (2001) Clin Immunol , vol.101 , pp. 201-210
    • Feldman, S.1    Stein, D.2    Amrute, S.3    Denny, T.4    Garcia, Z.5
  • 14
    • 0036569399 scopus 로고    scopus 로고
    • Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals
    • Chehimi J, Campbell DE, Azzoni L, Bacheller D, Papasavvas E, et al. (2002) Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol 168: 4796-4801.
    • (2002) J Immunol , vol.168 , pp. 4796-4801
    • Chehimi, J.1    Campbell, D.E.2    Azzoni, L.3    Bacheller, D.4    Papasavvas, E.5
  • 15
    • 0035883082 scopus 로고    scopus 로고
    • Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients
    • Soumelis V, Scott I, Gheyas F, Bouhour D, Cozon G, et al. (2001) Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood 98: 906-912.
    • (2001) Blood , vol.98 , pp. 906-912
    • Soumelis, V.1    Scott, I.2    Gheyas, F.3    Bouhour, D.4    Cozon, G.5
  • 16
    • 1842581705 scopus 로고    scopus 로고
    • Selective impairments in dendritic cell associated function distinguish HCV and HIV infection
    • Anthony DD, Yonkers NL, Post AB, Asaad R, Heinzel FP, et al. (2004) Selective impairments in dendritic cell associated function distinguish HCV and HIV infection. J Immunol 172: 4907-4916.
    • (2004) J Immunol , vol.172 , pp. 4907-4916
    • Anthony, D.D.1    Yonkers, N.L.2    Post, A.B.3    Asaad, R.4    Heinzel, F.P.5
  • 17
    • 0032950671 scopus 로고    scopus 로고
    • Depletion in blood CD11c-positive dendritic cells from HIV-infected patients
    • Grassi F, Hosmalin A, McIlroy D, Calvez V, Debre P, et al. (1999) Depletion in blood CD11c-positive dendritic cells from HIV-infected patients. AIDS 13: 759-766.
    • (1999) AIDS , vol.13 , pp. 759-766
    • Grassi, F.1    Hosmalin, A.2    McIlroy, D.3    Calvez, V.4    Debre, P.5
  • 18
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1
    • Donaghy H, Gazzard B, Gotch F, Patterson S, (2003) Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1. Blood 101: 4505-4511.
    • (2003) Blood , vol.101 , pp. 4505-4511
    • Donaghy, H.1    Gazzard, B.2    Gotch, F.3    Patterson, S.4
  • 19
    • 0035892117 scopus 로고    scopus 로고
    • Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection
    • Pacanowski J, Kahi S, Baillet M, Lebon P, Deveau C, et al. (2001) Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection. Blood 98: 3016-3021.
    • (2001) Blood , vol.98 , pp. 3016-3021
    • Pacanowski, J.1    Kahi, S.2    Baillet, M.3    Lebon, P.4    Deveau, C.5
  • 20
    • 42649126710 scopus 로고    scopus 로고
    • Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection
    • Dillon SM, Robertson KB, Pan SC, Mawhinney S, Meditz AL, et al. (2008) Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection. J Acquir Immune Defic Syndr 48: 1-12.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 1-12
    • Dillon, S.M.1    Robertson, K.B.2    Pan, S.C.3    Mawhinney, S.4    Meditz, A.L.5
  • 21
    • 77955249196 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients
    • Lehmann C, Lafferty M, Garzino-Demo A, Jung N, Hartmann P, et al. (2010) Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients. PLoS One 5: e11110.
    • (2010) PLoS One , vol.5
    • Lehmann, C.1    Lafferty, M.2    Garzino-Demo, A.3    Jung, N.4    Hartmann, P.5
  • 22
    • 77954169603 scopus 로고    scopus 로고
    • Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction
    • Meera S, Madhuri T, Manisha G, Ramesh P, (2010) Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction. Viral Immunol 23: 241-249.
    • (2010) Viral Immunol , vol.23 , pp. 241-249
    • Meera, S.1    Madhuri, T.2    Manisha, G.3    Ramesh, P.4
  • 23
    • 41349107635 scopus 로고    scopus 로고
    • Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection
    • Lester RT, Yao XD, Ball TB, McKinnon LR, Kaul R, et al. (2008) Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection. AIDS 22: 685-694.
    • (2008) AIDS , vol.22 , pp. 685-694
    • Lester, R.T.1    Yao, X.D.2    Ball, T.B.3    McKinnon, L.R.4    Kaul, R.5
  • 24
    • 78149442321 scopus 로고    scopus 로고
    • Evidence of dysregulation of dendritic cells in primary HIV infection
    • blood-2010-2003-273763
    • Sabado RL, O'Brien M, Subedi A, Qin L, Hu N, et al. (2010) Evidence of dysregulation of dendritic cells in primary HIV infection. Blood pp. blood-2010-2003-273763.
    • (2010) Blood
    • Sabado, R.L.1    O'Brien, M.2    Subedi, A.3    Qin, L.4    Hu, N.5
  • 25
    • 40949099876 scopus 로고    scopus 로고
    • Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands
    • Martinson JA, Roman-Gonzalez A, Tenorio AR, Montoya CJ, Gichinga CN, et al. (2007) Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands. Cell Immunol 250: 75-84.
    • (2007) Cell Immunol , vol.250 , pp. 75-84
    • Martinson, J.A.1    Roman-Gonzalez, A.2    Tenorio, A.R.3    Montoya, C.J.4    Gichinga, C.N.5
  • 26
    • 67349216345 scopus 로고    scopus 로고
    • Studies on toll-like receptor stimuli responsiveness in HIV-1 and HIV-2 infections
    • Nowroozalizadeh S, Mansson F, da Silva Z, Repits J, Dabo B, et al. (2009) Studies on toll-like receptor stimuli responsiveness in HIV-1 and HIV-2 infections. Cytokine 46: 325-331.
    • (2009) Cytokine , vol.46 , pp. 325-331
    • Nowroozalizadeh, S.1    Mansson, F.2    da Silva, Z.3    Repits, J.4    Dabo, B.5
  • 27
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: new mechanisms, molecules and clinical significance
    • Biswas SK, Lopez-Collazo E, (2009) Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol 30: 475-487.
    • (2009) Trends Immunol , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 28
    • 41949103790 scopus 로고    scopus 로고
    • Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro
    • Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu AA, et al. (2008) Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro. J Virol 82: 3997-4006.
    • (2008) J Virol , vol.82 , pp. 3997-4006
    • Tilton, J.C.1    Manion, M.M.2    Luskin, M.R.3    Johnson, A.J.4    Patamawenu, A.A.5
  • 29
    • 16344367898 scopus 로고    scopus 로고
    • ELISPOT analysis of hepatitis C virus protein-specific IFN-gamma- producing peripheral blood lymphocytes in infected humans with and without cirrhosis
    • Anthony DD, Post AB, Valdez H, Peterson DL, Murphy M, et al. (2001) ELISPOT analysis of hepatitis C virus protein-specific IFN-gamma- producing peripheral blood lymphocytes in infected humans with and without cirrhosis. Clin Immunol 99: 232-240.
    • (2001) Clin Immunol , vol.99 , pp. 232-240
    • Anthony, D.D.1    Post, A.B.2    Valdez, H.3    Peterson, D.L.4    Murphy, M.5
  • 30
    • 0034651907 scopus 로고    scopus 로고
    • Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity
    • Karulin A, Hesse M, Tary-Lehmann M, Lehmann P, (2000) Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity. J Immunol 164: 1862-1872.
    • (2000) J Immunol , vol.164 , pp. 1862-1872
    • Karulin, A.1    Hesse, M.2    Tary-Lehmann, M.3    Lehmann, P.4
  • 31
    • 33947661034 scopus 로고    scopus 로고
    • TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection
    • Yonkers NL, Rodriguez B, Milkovich KA, Asaad R, Lederman MM, et al. (2007) TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection. J Immunol 178: 4436-4444.
    • (2007) J Immunol , vol.178 , pp. 4436-4444
    • Yonkers, N.L.1    Rodriguez, B.2    Milkovich, K.A.3    Asaad, R.4    Lederman, M.M.5
  • 32
    • 58149339765 scopus 로고    scopus 로고
    • B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
    • Wang X, Zhang Z, Zhang S, Fu J, Yao J, et al. (2008) B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection. Eur J Immunol 38: 3226-3236.
    • (2008) Eur J Immunol , vol.38 , pp. 3226-3236
    • Wang, X.1    Zhang, Z.2    Zhang, S.3    Fu, J.4    Yao, J.5
  • 33
    • 10344226171 scopus 로고    scopus 로고
    • PD-1 ligands, negative regulators for activation of naïve, memory, and recently activated human CD4+ T cells
    • Cai G, Karni A, Oliveira EML, Weiner HL, Hafler DA, et al. (2004) PD-1 ligands, negative regulators for activation of naïve, memory, and recently activated human CD4+ T cells. Cellular Immunology 230: 89-98.
    • (2004) Cellular Immunology , vol.230 , pp. 89-98
    • Cai, G.1    Karni, A.2    Oliveira, E.M.L.3    Weiner, H.L.4    Hafler, D.A.5
  • 34
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354.
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1    Kaufmann, D.E.2    Kiepiela, P.3    Brown, J.A.4    Moodley, E.S.5
  • 35
    • 0038784354 scopus 로고    scopus 로고
    • B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression
    • Trabattoni D, Saresella M, Biasin M, Boasso A, Piacentini L, et al. (2003) B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood 101: 2514-2520.
    • (2003) Blood , vol.101 , pp. 2514-2520
    • Trabattoni, D.1    Saresella, M.2    Biasin, M.3    Boasso, A.4    Piacentini, L.5
  • 36
    • 43149121106 scopus 로고    scopus 로고
    • Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands
    • Meier A, Bagchi A, Sidhu HK, Alter G, Suscovich TJ, et al. (2008) Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands. AIDS 22: 655-658.
    • (2008) AIDS , vol.22 , pp. 655-658
    • Meier, A.1    Bagchi, A.2    Sidhu, H.K.3    Alter, G.4    Suscovich, T.J.5
  • 37
    • 35748957454 scopus 로고    scopus 로고
    • Striking Dichotomy of PD-L1 and PD-L2 Pathways in Regulating Alloreactive CD4+ and CD8+ T Cells In Vivo
    • Habicht A, Kewalaramani R, Vu MD, Demirci G, Blazar BR, et al. (2007) Striking Dichotomy of PD-L1 and PD-L2 Pathways in Regulating Alloreactive CD4+ and CD8+ T Cells In Vivo. American Journal of Transplantation 7: 2683-2692.
    • (2007) American Journal of Transplantation , vol.7 , pp. 2683-2692
    • Habicht, A.1    Kewalaramani, R.2    Vu, M.D.3    Demirci, G.4    Blazar, B.R.5
  • 39
    • 65249133450 scopus 로고    scopus 로고
    • Immunoglobulin-like transcript 3: A crucial regulator of dendritic cell function
    • Vlad G, Chang C-C, Colovai AI, Berloco P, Cortesini R, et al. (2009) Immunoglobulin-like transcript 3: A crucial regulator of dendritic cell function. Human Immunology 70: 340-344.
    • (2009) Human Immunology , vol.70 , pp. 340-344
    • Vlad, G.1    Chang, C.-C.2    Colovai, A.I.3    Berloco, P.4    Cortesini, R.5
  • 41
    • 0025896328 scopus 로고
    • Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes
    • Bazil V, Strominger JL, (1991) Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes. J Immunol 147: 1567-1574.
    • (1991) J Immunol , vol.147 , pp. 1567-1574
    • Bazil, V.1    Strominger, J.L.2
  • 42
    • 0032530736 scopus 로고    scopus 로고
    • Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events
    • Lien E, Aukrust P, Sundan A, Muller F, Froland SS, et al. (1998) Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood 92: 2084-2092.
    • (1998) Blood , vol.92 , pp. 2084-2092
    • Lien, E.1    Aukrust, P.2    Sundan, A.3    Muller, F.4    Froland, S.S.5
  • 43
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: the tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H, (2002) Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 80: 477-483.
    • (2002) Immunol Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 45
    • 0035366248 scopus 로고    scopus 로고
    • The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics
    • Lanzavecchia A, Sallusto F, (2001) The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics. Curr Opin Immunol 13: 291-298.
    • (2001) Curr Opin Immunol , vol.13 , pp. 291-298
    • Lanzavecchia, A.1    Sallusto, F.2
  • 46
    • 0036136322 scopus 로고    scopus 로고
    • Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses
    • Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, et al. (2002) Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. J Immunol 168: 197-206.
    • (2002) J Immunol , vol.168 , pp. 197-206
    • Fanales-Belasio, E.1    Moretti, S.2    Nappi, F.3    Barillari, G.4    Micheletti, F.5
  • 47
    • 30744448648 scopus 로고    scopus 로고
    • HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood
    • Granelli-Piperno A, Shimeliovich I, Pack M, Trumpfheller C, Steinman RM, (2006) HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood. J Immunol 176: 991-998.
    • (2006) J Immunol , vol.176 , pp. 991-998
    • Granelli-Piperno, A.1    Shimeliovich, I.2    Pack, M.3    Trumpfheller, C.4    Steinman, R.M.5
  • 48
    • 10344226171 scopus 로고    scopus 로고
    • PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells
    • Cai G, Karni A, Oliveira EM, Weiner HL, Hafler DA, et al. (2004) PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells. Cell Immunol 230: 89-98.
    • (2004) Cell Immunol , vol.230 , pp. 89-98
    • Cai, G.1    Karni, A.2    Oliveira, E.M.3    Weiner, H.L.4    Hafler, D.A.5
  • 49
    • 43249118045 scopus 로고    scopus 로고
    • Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review
    • Danesh J, Kaptoge S, Mann AG, Sarwar N, Wood A, et al. (2008) Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. PLoS Med 5: e78.
    • (2008) PLoS Med , vol.5
    • Danesh, J.1    Kaptoge, S.2    Mann, A.G.3    Sarwar, N.4    Wood, A.5
  • 50
    • 42149122168 scopus 로고    scopus 로고
    • Interruption of antiretroviral therapy and risk of cardiovascular disease in persons with HIV-1 infection: exploratory analyses from the SMART trial
    • Phillips AN, Carr A, Neuhaus J, Visnegarwala F, Prineas R, et al. (2008) Interruption of antiretroviral therapy and risk of cardiovascular disease in persons with HIV-1 infection: exploratory analyses from the SMART trial. Antivir Ther 13: 177-187.
    • (2008) Antivir Ther , vol.13 , pp. 177-187
    • Phillips, A.N.1    Carr, A.2    Neuhaus, J.3    Visnegarwala, F.4    Prineas, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.