Inflammasome-dependent IFN-γ drives pathogenesis in streptococcus pneumoniae meningitis

Journal of Immunology

Volumn 189, Issue 10, 2012, Pages 4970-4980

  Mitchell, Andrew J ^a,b   Yau, Belinda ^a   McQuillan, James A ^a   Ball, Helen J ^a   Too, Lay Khoon ^a   Abtin, Arby ^b   Hertzog, Paul ^c   Leib, Stephen L ^d   Jones, Cheryl A ^a,e   Gerega, Sebastien K ^e   Weninger, Wolfgang ^b   Hunt, Nicholas H ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CENTENARY INSTITUTE   (Australia)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF BERN   (Switzerland)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 18; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL LOAD; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; GAMMA INTERFERON GENE; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INDUCTION; INFLAMMATION; MALE; MOLECULAR PATHOLOGY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WILD TYPE;

ANIMALS; CHEMOKINE CCL2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMASOMES; INTERFERON-GAMMA; INTERLEUKIN-18; MENINGITIS, PNEUMOCOCCAL; MICE; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE; STREPTOCOCCUS PNEUMONIAE;

EID: 84868586467     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201687     Document Type: Article

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