Neuroinflammatory role of prostaglandins during experimental meningitis: Evidence suggestive of an in vivo relationship between nitric oxide and prostaglandins

Journal of Pharmacology and Experimental Therapeutics

Volumn 304, Issue 1, 2003, Pages 319-325

  Boje, Kathleen M K ^a   Jaworowicz Jr , David ^a,b   Raybon, Joseph J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b Albany Medical College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; BACTERIUM LIPOPOLYSACCHARIDE; CYCLOOXYGENASE 2; NIMESULIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; BLOOD BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; CEREBROSPINAL FLUID; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME SYNTHESIS; EVIDENCE BASED MEDICINE; IN VIVO STUDY; INFLAMMATION; MALE; MEDIATOR; MENINGITIS; MENINX; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; STATISTICAL ANALYSIS;

ANIMALS; BLOOD-BRAIN BARRIER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; GUANIDINES; ISOENZYMES; LIPOPOLYSACCHARIDES; MALE; MENINGITIS; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES;

EID: 0037214477     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.041533     Document Type: Article

References (40)

1. Adamson DC, Wildemann B, Sasaki M, Glass JD, McArthur JC, Christov VI, Dawson TM, and Dawson VL (1996) Immunologic NO synthase: Elevation in severe AIDS dementia and induction by HIV-1 gp41. Science (Wash DC) 274:1917-1921.
2. Beckman JS, Chen J, Crow JP, and Ye YZ (1994) Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. Prog Brain Res 103:371-380.
3. Boje KM and Arora PK (1992) Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res 587:250-256.
4. Boje KMK (1995a) Cerebrovascular permeability changes during experimental meningitis in the rat. J Pharmacol Exp Ther 274:1199-1203.
5. Boje KMK (1995b) Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental meningitis in the rat. Eur J Pharmacol 272:297-300.
6. Boje KMK (1996) Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis. Brain Res. 720:75-83.
7. Boje KMK (1998) The Role of Glial Nitric Oxide in Neurotoxicity and Central Nervous System Diseases (Wood PL ed) pp 331-354, Humana Press, Totowa, NJ.
8. Boje KMK and Lakhman SS (2000) Nitric oxide redox species exert differential permeability effects on the blood-brain barrier. J Pharmacol Exp Ther 293:545-550.
9. Breitner JCS (1996) Inflammatory processes and antiinflammatory drugs in Alzheimers disease - A current appraisal. Neurobiol Aging 17:789-794.
10. Campbell IL (1996) Exacerbation of lymphocytic choriomeningitis in mice treated with the inducible nitric oxide synthase inhibitor aminoguanidine. J Neuroimmunol 71:31-36.
11. Claudio L, Raine CS, and Brosnan CF (1995) Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis. Acta Neuropathol 90:228-238.
12. Corbett JA, Kwon G, Turk J, and McDaniel ML (1993) IL-1b induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of langerhans: Activation of cyclooxygenase by nitric oxide. Biochemistry 32:13767-13770.
13. Dapino P, Ottenello L, and Dallegri F (1994) The anti-inflammatory drug nimesulide inhibits neutrophil adherence to and migration across monolayers of cytokine-activated endothelial cells. Respiration 61:336-341.
14. de Vries HE, Hoogendoorn KH, van Dijk J, Zijlstra FJ, van Dam AM, Breimer DD, van Berkel TJC, de Boer AG, and Kuiper J (1995) Eicosanoid production by rat cerebral endothelial cells: Stimulation by lipopolysaccharide, interleukin-1 and interleukin-6. J Neuroimmunol 59:1-8.
15. de Vries HE, Kuiper J, de Boer AG, van Berkel TJC, and Breimer DD (1997) The blood-brain barrier in neuroinflammatory diseases. Pharmacol Rev 49:143-155.
16. Galea E and Feinstein DL (1999) Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP. FASEB J 13:2125-2137.
17. Goodwin DC, Landino LM, and Marnett LJ (1999) Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis. FASEB J 13:1121-1136.
18. Jaworowicz DJ, Filipowski MT, and Boje KMK (1999) An improved high pressure liquid chromatographic assay for nimesulide. J Chromatogr B Biomed Sci Appl 723:293-299.
19. Jaworowicz DJ, Korytko PJ, Lakhman SS, and Boje KMK (1998) Nitric oxide and prostaglandin E2 formation parallels blood-brain barrier disruption in an experimental rat model of bacterial meningitis. Brain Res Bull 46:541-546.
20. Kadurugamuwa JL, Hengstler B, Bray MA, and Zak O (1989a) Inhibition of complement-factor-5a-induced inflammatory reactions by prostaglandin E2 in experimental meningitis. J Infect Dis 160:715-719.
21. Kadurugamuwa JL, Hengstler B, and Zak O (1989b) Cerebrospinal fluid protein profile in experimental pneumococcal meningitis and its alteration by ampicillin and anti-inflammatory agents. J Infect Dis 159:26-34.
22. Kilbourn RG and Belloni P (1990) Endothelial cell production of nitrogen oxides in response to interferon gamma in combination with tumor necrosis factor, interleukin-1, or endotoxin. J Natl Cancer Inst 82:772-776.
23. Koedel U, Bernatowicz A, Paul R, Frei K, Fontana A, and Pfister HW (1995) Experimental pneumococcal meningitis: Cerebrovascular alterations, brain edema and meningeal inflammation are linked to the production of nitric oxide. Ann Neurol 37:313-323.
24. Korytko PJ and Boje KMK (1996) Pharmacological characterization of nitric oxide production in a rat model of meningitis. Neuropharmacology 35:231-237.
25. Lee SC, Dickson DW, Brosnan CF, and Casadevall A (1994) Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism. J Exp Med 180:365-369.
26. Leib SL, Kim YS, Black SM, Tureen JH, and Tauber MG (1998) Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. J Infect Dis 177:692-699.
27. Lowry O, Rosebrough N, Farr A, and Randall R (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275.
28. McGeer PL and McGeer EG (1995) The inflammatory response system of brain: Implication for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 21:195-218.
29. Minghetti L and Levi G (1995) Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures. J Neurochem 65: 2690-2698.
30. Misko TP, Trotter JL, and Cross AH (1995) Mediation of inflammation by encephalitogenic cells: Interferon gamma induction of nitric oxide synthase and cyclooxygenase 2. J Neuroimmunol 61:195-204.
31. Mitchell JA, Larkin S, and Williams TJ (1995) Cyclooxygenase-2: Regulation and relevance in inflammation. Biochem Pharmacol 50:1535-1542.
32. Molinaholgado F, Lledo A, and Guaza C (1995) Evidence for cyclooxygenase activation by nitric oxide in astrocytes. Glia 15:167-172.
33. Rose JW, Hill KE, Wada Y, Kurtz CIB, Tsundoa I, Fujinami RS, and Cross AH (1998) Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyleination produced by Theiler's virus infection. J Neuroimmunol 81:82-89.
34. Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, and Needleman P (1994) Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Investig 93:1940-1947.
35. Stamler JS, Singel DJ, and Loscalzo J (1992) Biochemistry of nitric oxide and its redox-activated forms. Science (Wash DC) 258:1898-1902.
36. Tomimoto H, Akiguchi I, Suenaga T, Nishimura M, Wakita H, Nakamura S, and Kimura J (1996) Alterations of the blood-brain barrier and glial cells in whitematter lesions in cerebrovascular and Alzheimers disease patients. Stroke 27: 2069-2074.
37. Tuomanen E, Hengstler B, Rich R, Bray MA, Zak O, and Tomasz A (1987) Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis. J Infect Dis 155:985-990.
38. Vane JR and Botting RM (1995) New insights into the mode of action of antiinflammatory drugs. Inflamm Res 44:1-10.
39. Vane JR, Mitchel JA, Appleton I, Tomlinson A, Bishop-Bailey D, Croxtall J, and Willoughby DA (1994) Inducible isoforms of cyclooxygenase and nitric oxide synthase in inflammation. Proc Natl Acad Sci USA 91:2046-2050.
40. Zhang FY, Casey RM, Ross ME, and Iadecola C (1996) Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke 27:317-323.