Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation

Journal of Infectious Diseases

Volumn 186, Issue 6, 2002, Pages 798-806

  Echchannaoui, Hakim ^a   Frei, Karl ^c   Schnell, Christian ^b   Leib, Stephen L ^d   Zimmerli, Werner ^a   Landmann, Regine ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTRIAXONE; INTERLEUKIN 6; LUCIFERASE; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL MENINGITIS; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE PREDISPOSITION; GRAM POSITIVE BACTERIUM; IMMUNE RESPONSE; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME;

ANIMALS; CEFTRIAXONE; CEPHALOSPORINS; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; DROSOPHILA PROTEINS; INFLAMMATION; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MEMBRANE GLYCOPROTEINS; MENINGITIS, BACTERIAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMOCOCCAL INFECTIONS; RECEPTORS, CELL SURFACE; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS;

EID: 0037105727     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/342845     Document Type: Article

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