Interferon-γ-inducing factor (IL-18) and interferon-γ in inflammatory CNS diseases

Neurology

Volumn 53, Issue 5, 1999, Pages 1104-1106

  Fassbender, K ^b   Mielke, O ^c   Bertsch, T ^c   Muehlhauser, F ^c   Hennerici, M ^c   Kurimoto, M ^a   Rossol, S ^c  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c NONE

Author keywords

Bacterial meningitis; Interleukin 18; MS

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIAL MENINGITIS; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; INTERFERON PRODUCTION; MAJOR CLINICAL STUDY; MALE; MENINGOENCEPHALITIS; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0033595448     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.53.5.1104     Document Type: Article

References (15)

1. Okamura H, Tsutsui H, Komatsu T, et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995;378:88-91.
2. Dinarello CA, Novick D, Puren AJ, et al. Overview of interleukin-18: more than an interferon-gamma inducing factor. J Leukoc Biol 1998;63:658-664.
3. intIL-2R β+ T cells. J Immunol 1998;161:1483-1492.
4. Sareneva T, Matikainen S, Kurimoto M, Julkunen I. Influenza A virus-induced IFN-α/β and IL-18 synergistically enhance IFN-γ gene expression in human T cells. J Immunol 1998;160:6032-6038.
5. Bohn E, Sing A, Zumbihl R, et al. IL-18 (IFN-γ-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice. J Immunol 1998;160:299-307.
6. Rothe H, Hibino T, Itoh Y, et al. Systemic production of interferon-gamma inducing factor (IGIF) versus local IFN-γ expression involved in the development of Th1 insulinitis in NOD mice. J Autoimmun 1997:10:251-256.
7. Panitch HS, Haley AS, Hirsch RI, Johnson KP. Exacerbations of multiple sclerosis in patients treated with gamma-interferon. Lancet 1987;i:893-895.
8. Horwitz MS, Evans CF, McGavern DB, et al. Primary demyelination in transgenic mice expressing interferon-gamma. Nat Med 1997:3:1037-1041.
9. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983:13:227-231.
10. Stoll S, Jonuleit H, Schmitt E, et al. Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development. Eur J Immunol 1998;28:3231-3239.
11. Rossol S, Marinos G, Carucci P, et al. Interleukin-12 induction of Th1 cytokines is important for viral clearance in chronic hepatitis B. J Clin Invest 1997;99:3025-3033.
12. Fassbender K, Ries S. Schminke U, et al. Inflammatory cytokines in CSF in bacterial meningitis: association with altered blood flow velocities in basal cerebral arteries. J Neurol Neurosurg Psychiatr 1996;61:57-61.
13. Kawakami K, Qureshi MH, Zhang T, Okamura H, Kurimoto M, Saito A. IL-18 protects mice against pulmonary and disseminated infection with Cryptococcus neoformans by inducing IFN-gamma production. J Immunol 1997;159:5528-5534.
14. Takeda K, Tsutsui H, Yoshimoto T, et al. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 1998;8:383-390.
15. Tsutsui H, Matsui K, Kawada N et al. IL-18 accounts for both TNF-α- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice. J Immunol 1997;159: 3961-3967.