Relating hydrogen-bonding interactions with the phase behavior of naproxen/PVP K 25 solid dispersions: Evaluation of solution-cast and quench-cooled films

Molecular Pharmaceutics

Volumn 9, Issue 11, 2012, Pages 3301-3317

  Paudel, Amrit ^a   Nies, Erik ^a   Van Den Mooter, Guy ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

amorphous solid dispersion; H bonding; kinetic miscibility; phase behavior; quench cooled films; solution IR; solution cast films

Indexed keywords

NAPROXEN; POVIDONE;

ABSORPTION; ARTICLE; DISPERSION; DRUG SOLUBILITY; FLORY HUGGINS THEORY; HEAT; HYDROGEN BOND; HYDROPHOBICITY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; SOLID; SOLUBILITY; THERMODYNAMICS; X RAY POWDER DIFFRACTION;

DRUG COMPOUNDING; DRUG STABILITY; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NAPROXEN; PHASE TRANSITION; POVIDONE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 84868585792     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3003495     Document Type: Article

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