Small scale screening to determine the ability of different polymers to inhibit drug crystallization upon rapid solvent evaporation

Molecular Pharmaceutics

Volumn 7, Issue 4, 2010, Pages 1328-1337

  Van Eerdenbrugh, Bernard ^a   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

amorphous state; Crystallization; physical stability; polymeric additives; solvent evaporation; spin coating; stabilization

Indexed keywords

BENZAMIDE; BIFONAZOLE; CHLORPROPAMIDE; CHLORZOXAZONE; EUDRAGIT; FLUFENAMIC ACID; FLURBIPROFEN; HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; LIDOCAINE; PHENACETIN; POLY(VINYLPYRROLIDONE VINYL ACETATE); POLYACRYLIC ACID; POLYMER; POLYSTYRENESULFONIC ACID; POVIDONE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; DISPERSION; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; EVAPORATION; PRIORITY JOURNAL;

ACRYLATES; BENZAMIDES; CHLORPROPAMIDE; CHLORZOXAZONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLIZATION; FLURBIPROFEN; IMIDAZOLES; LIDOCAINE; METHYLCELLULOSE; PHENACETIN; POLYMERS; POLYVINYLS; POVIDONE; PYRROLIDINES; SOLVENTS;

EID: 77955242670     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp1001153     Document Type: Article

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