Molecular characterization of immunoglobulin gene rearrangements in diffuse large B-cell lymphoma: Antigen-driven origin and IGHV4-34 as a particular subgroup of the non-GCB subtype

American Journal of Pathology

Volumn 181, Issue 5, 2012, Pages 1879-1888

  Sebastián, Elena ^a,b   Alcoceba, Miguel ^a,b   Balanzategui, Ana ^a,b   Marín, Luis ^a,b   Montes Moreno, Santiago ^c   Flores, Teresa ^a   González, David ^d   Sarasquete, M Eugenia ^a,b   Chillón, M Carmen ^a,b   Puig, Noemí ^a,b   Corral, Rocío ^a,b   Pardal, Emilia ^c   Martín, Alejandro ^a,b,c   González Barca, Eva ^c   Caballero, M Dolores ^a,c   San Miguel, Jesús F ^a,c,e   García Sanz, Ramón ^a,c,e   González, Marcos ^a,c,e  

^a HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^b INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE SALAMANCA IBSAL   (Spain)

^c HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e Centro de Investigacion del Cancer   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; IMMUNOGLOBULIN HEAVY CHAIN; RITUXIMAB;

ADOLESCENT; ADULT; AGED; ARTICLE; DNA EXTRACTION; FEMALE; FOLLOW UP; GENE REARRANGEMENT; GENE SEQUENCE; HUMAN; IGHD GENE; IGHJ GENE; IGHV GENE; IMMUNOGENETICS; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR GENETICS; PRIORITY JOURNAL; SOMATIC HYPERMUTATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; AMINO ACIDS; ANTIGENS, NEOPLASM; CLONE CELLS; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GERMINAL CENTER; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOHISTOCHEMISTRY; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; V(D)J RECOMBINATION; YOUNG ADULT;

EID: 84868121638     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.07.028     Document Type: Article

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