Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression

European Journal of Immunology

Volumn 27, Issue 6, 1997, Pages 1398-1405

  Küppers, Ralf ^a   Rajewsky, Klaus ^a   Hansmann, Martin Leo ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Diffuse large cell lymphoma; Somatic hypermutation; V gene

Indexed keywords

ANTIBODY;

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; GERMINAL CENTER; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOBLAST; IMMUNOGLOBULIN GENE; LARGE CELL LYMPHOMA; MALE; MEMORY CELL; PRIORITY JOURNAL; SOMATIC MUTATION; T LYMPHOCYTE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODY FORMATION; B-LYMPHOCYTES; BASE SEQUENCE; CELL DIFFERENTIATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOMA, LARGE-CELL, DIFFUSE; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 1842290375     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270616     Document Type: Article

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