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Volumn 256, Issue 3, 1996, Pages 577-589

The I binding specificity of human VH4-34 (VH4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3

Author keywords

Antibody engineering; Baculovirus expression system; Framework region 1; Human cold agglutinins; I binding

Indexed keywords

COLD AGGLUTININ; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY;

EID: 0029979577     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0110     Document Type: Article
Times cited : (89)

References (77)
  • 1
    • 0013787006 scopus 로고
    • Anti-I antibody in normal human newborn infants
    • Adinolfi, M. (1965). Anti-I antibody in normal human newborn infants. Immunology, 9, 43-52.
    • (1965) Immunology , vol.9 , pp. 43-52
    • Adinolfi, M.1
  • 2
    • 0027095905 scopus 로고
    • Probing the human antibody repertoire to exogenous antigens: Characterization of the H and L chain V region gene segments from anti-hepatitis B virus antibodies
    • Andris, J. S., Ehrlich, P. H., Ostberg, L. & Capra, J. D. (1992). Probing the human antibody repertoire to exogenous antigens: characterization of the H and L chain V region gene segments from anti-hepatitis B virus antibodies. J. Immunol. 149, 4053-4059.
    • (1992) J. Immunol. , vol.149 , pp. 4053-4059
    • Andris, J.S.1    Ehrlich, P.H.2    Ostberg, L.3    Capra, J.D.4
  • 4
    • 0027444774 scopus 로고
    • Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord blood cells
    • Bhat, N. M., Bieber, M. M., Chapman, C. J., Stevenson, F. K. & Teng, N. N. H. (1993). Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord blood cells. J. Immunol. 151, 5011-5021.
    • (1993) J. Immunol. , vol.151 , pp. 5011-5021
    • Bhat, N.M.1    Bieber, M.M.2    Chapman, C.J.3    Stevenson, F.K.4    Teng, N.N.H.5
  • 6
    • 0027053660 scopus 로고
    • Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutaion and repertoire shift
    • Bye, M. M., Carter, C., Cui, Y, Gorick, B. D., Songsivlai, S., Winter, G., Hughes-Jones, N. C. & Marks, J. D. (1992). Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutaion and repertoire shift. J. Clin. Invest. 90, 2481-2490.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2481-2490
    • Bye, M.M.1    Carter, C.2    Cui, Y.3    Gorick, B.D.4    Songsivlai, S.5    Winter, G.6    Hughes-Jones, N.C.7    Marks, J.D.8
  • 9
    • 0020684155 scopus 로고
    • Evidence for the occurrence of O-glycosidically linked oligosaccharides of poly-N-acetyllactosamine type on the human leucocyte common
    • Childs, R. A., Dalchau, R., Scudder, P. Hounsell, E. F., Fabre J. W. & Feizi, T. (1983). Evidence for the occurrence of O-glycosidically linked oligosaccharides of poly-N-acetyllactosamine type on the human leucocyte common. Biochem. Biophys. Res. Commun. 110, 424-431.
    • (1983) Biochem. Biophys. Res. Commun. , vol.110 , pp. 424-431
    • Childs, R.A.1    Dalchau, R.2    Scudder, P.3    Hounsell, E.F.4    Fabre, J.W.5    Feizi, T.6
  • 10
    • 0020596513 scopus 로고
    • Association of bacterial carbohydrate-specific cold agglutinin antibody production with immunization by group C, group B type III, and Streptococcus pneumoniae type XIV streptococcal vaccines
    • Colling, R. G., Pearson, T. C. & Brown, J. C. (1983). Association of bacterial carbohydrate-specific cold agglutinin antibody production with immunization by group C, group B Type III, and Streptococcus pneumoniae type XIV streptococcal vaccines. Infect. Immunol. 41, 205-213.
    • (1983) Infect. Immunol. , vol.41 , pp. 205-213
    • Colling, R.G.1    Pearson, T.C.2    Brown, J.C.3
  • 12
    • 0041615392 scopus 로고
    • Experimental production of cold agglutinins in rabbits
    • Costea, M., Yakulis, V. & Heller, P. (1965). Experimental production of cold agglutinins in rabbits. Blood, 26, 323-340.
    • (1965) Blood , vol.26 , pp. 323-340
    • Costea, M.1    Yakulis, V.2    Heller, P.3
  • 13
    • 0029061664 scopus 로고
    • Heavy chain variable region, light chain variable region, and heavy chain CDR3 influences on the mono- and poly reactivity and on the affinity of human monoclonal rheumatoid factors
    • Crouzier, R., Martin, T. & Pasquali, J.-L. (1995). Heavy chain variable region, light chain variable region, and heavy chain CDR3 influences on the mono- and poly reactivity and on the affinity of human monoclonal rheumatoid factors. J. Immunol. 153, 4526-4535.
    • (1995) J. Immunol. , vol.153 , pp. 4526-4535
    • Crouzier, R.1    Martin, T.2    Pasquali, J.-L.3
  • 15
    • 0014217729 scopus 로고
    • Lambda chains in cold agglutinins
    • Feizi, T. (1967a). Lambda chains in cold agglutinins. Science, 156, 1111-1112.
    • (1967) Science , vol.156 , pp. 1111-1112
    • Feizi, T.1
  • 16
    • 0014220663 scopus 로고
    • Monotypic cold agglutinins in infection by Mycoplasma pneumoniae
    • Feizi, T. (1967b). Monotypic cold agglutinins in infection by Mycoplasma pneumoniae. Nature, 215, 540-542.
    • (1967) Nature , vol.215 , pp. 540-542
    • Feizi, T.1
  • 17
    • 84907111482 scopus 로고
    • The blood group Ii system: A carbohydrate antigen system defined by naturally monoclonal or oligoclonal autoantibodies of man
    • Feizi, T. (1981). The blood group Ii system: a carbohydrate antigen system defined by naturally monoclonal or oligoclonal autoantibodies of man. Immunol. Commun. 10, 127-156.
    • (1981) Immunol. Commun. , vol.10 , pp. 127-156
    • Feizi, T.1
  • 18
    • 0018741036 scopus 로고
    • Three types of blood group I specificity among monoclonal anti-I autoantibodies revealed by analogues of a branched erythrocyte glycolipid
    • Feizi, T., Childs, R. A., Watanabe, K. & Hakomori, S. I. (1979). Three types of blood group I specificity among monoclonal anti-I autoantibodies revealed by analogues of a branched erythrocyte glycolipid. J. Expt. Med. 149, 975-980.
    • (1979) J. Expt. Med. , vol.149 , pp. 975-980
    • Feizi, T.1    Childs, R.A.2    Watanabe, K.3    Hakomori, S.I.4
  • 19
    • 0026559783 scopus 로고
    • Antibody framework residues affecting the conformation of the hypervariable loops
    • Foote, J. & Winter, G. (1992). Antibody framework residues affecting the conformation of the hypervariable loops. J. Mol. Biol. 224, 487-499.
    • (1992) J. Mol. Biol. , vol.224 , pp. 487-499
    • Foote, J.1    Winter, G.2
  • 21
    • 0019443775 scopus 로고
    • Blood group ABH and Ii antigens of human erythrocytes: Chemistry polymorphism and their developmental change
    • Hakamori, S. (1981). Blood group ABH and Ii antigens of human erythrocytes: chemistry polymorphism and their developmental change. Semin. Hematol. 18, 39-62.
    • (1981) Semin. Hematol. , vol.18 , pp. 39-62
    • Hakamori, S.1
  • 22
    • 0025340630 scopus 로고
    • High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system
    • Hasemann, C. A. & Capra, J. D. (1990). High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system. Proc. Natl Acad. Sci. USA, 87, 3942-3946.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 3942-3946
    • Hasemann, C.A.1    Capra, J.D.2
  • 23
    • 0027156463 scopus 로고
    • Human B-cell clones expressing lupus nephritis-associated anti-DNA idiotypes are preferentially expanded without somatic mutation
    • Hirabayashi, Y, Munakata, Y, Takai, O., Shibata, S., Sasakim T. & Sano, H. (1993). Human B-cell clones expressing lupus nephritis-associated anti-DNA idiotypes are preferentially expanded without somatic mutation. Scand. J. Immunol. 37, 533-540.
    • (1993) Scand. J. Immunol. , vol.37 , pp. 533-540
    • Hirabayashi, Y.1    Munakata, Y.2    Takai, O.3    Shibata, S.4    Sasakim, T.5    Sano, H.6
  • 24
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K. & Pease, L. R. (1989). Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene, 77, 51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 29
    • 0025898888 scopus 로고
    • Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45
    • Justement, L. B., Campbell, K. S., Chien, N. C. & Cambier, J. C. (1991). Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45. Science, 252, 1839-1842.
    • (1991) Science , vol.252 , pp. 1839-1842
    • Justement, L.B.1    Campbell, K.S.2    Chien, N.C.3    Cambier, J.C.4
  • 30
    • 0025823716 scopus 로고
    • Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites
    • Kabat, E. A. & Wu, T. T. (1991). Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites. J. Immunol. 147, 1709-1719.
    • (1991) J. Immunol. , vol.147 , pp. 1709-1719
    • Kabat, E.A.1    Wu, T.T.2
  • 31
    • 0026336406 scopus 로고
    • Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries
    • Kang, A. S., Jones, T. M. & Burton, D. R. (1991). Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries. Proc. Natl Acad. Sci. USA, 88, 11120-11123.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 11120-11123
    • Kang, A.S.1    Jones, T.M.2    Burton, D.R.3
  • 32
    • 0029029375 scopus 로고
    • Evidence for the overexpression of the VH4-34 (VH4.21 ) ig gene segment in the normal adult human peripheral blood B cell repertoire
    • Kraj, P., Friedman, D. F., Stevenson, F. & Silberstein, L. E. (1995). Evidence for the overexpression of the VH4-34 (VH4.21 ) Ig gene segment in the normal adult human peripheral blood B cell repertoire. J. Immunol. 154, 6406-6420.
    • (1995) J. Immunol. , vol.154 , pp. 6406-6420
    • Kraj, P.1    Friedman, D.F.2    Stevenson, F.3    Silberstein, L.E.4
  • 33
    • 0025757249 scopus 로고
    • The primary structure of the Fab fragment of protein KAU, a monoclonal immunoglobulin M cold agglutinin
    • Leoni, L., Ghiso, J., Goni, F. & Frangione, B. (1991). The primary structure of the Fab fragment of protein KAU, a monoclonal immunoglobulin M cold agglutinin. J. Biol. Chem. 266, 2836-2842.
    • (1991) J. Biol. Chem. , vol.266 , pp. 2836-2842
    • Leoni, L.1    Ghiso, J.2    Goni, F.3    Frangione, B.4
  • 34
    • 0026612987 scopus 로고
    • Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection
    • Logtenberg, T., Schutte, M. E. M., Ebling, S. B., Gmelig-Meyling, F H. J. & van Es, J. H. (1992). Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection. Immunol. Rev. 128, 23-47.
    • (1992) Immunol. Rev. , vol.128 , pp. 23-47
    • Logtenberg, T.1    Schutte, M.E.M.2    Ebling, S.B.3    Gmelig-Meyling, F.H.J.4    Van Es, J.H.5
  • 35
    • 0014769477 scopus 로고
    • A lambda light chain cold agglutinin-cryomacroblobulin occurring in Waldenstrom's macroglobulinemia
    • Macris, N. T., Capra, J. D., Frankel, G. J., Ioachim, H. L., Satz, H. & Bruno, M. S. (1970). A lambda light chain cold agglutinin-cryomacroblobulin occurring in Waldenstrom's macroglobulinemia. Am. J. Med. 48, 524-529.
    • (1970) Am. J. Med. , vol.48 , pp. 524-529
    • Macris, N.T.1    Capra, J.D.2    Frankel, G.J.3    Ioachim, H.L.4    Satz, H.5    Bruno, M.S.6
  • 39
    • 0018926221 scopus 로고
    • Human homologue of mouse T200 glycoprotein
    • Omary M. B., Trobridge, I. & Battifora, H. (1980). Human homologue of mouse T200 glycoprotein. J. Expt. Med. 152, 842-852.
    • (1980) J. Expt. Med. , vol.152 , pp. 842-852
    • Omary, M.B.1    Trobridge, I.2    Battifora, H.3
  • 43
    • 0026700882 scopus 로고
    • Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3
    • Pascual, V., Victor, K., Randen, I., Thompson, K., Steinitz, M., Forre, O., Fu, S.-M., Natvig, J. B. & Capra, J. D. (1992a). Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3. Scand. J. Immunol. 36, 349-362.
    • (1992) Scand. J. Immunol. , vol.36 , pp. 349-362
    • Pascual, V.1    Victor, K.2    Randen, I.3    Thompson, K.4    Steinitz, M.5    Forre, O.6    Fu, S.-M.7    Natvig, J.B.8    Capra, J.D.9
  • 45
    • 0028226636 scopus 로고
    • Nucleotide sequence analysis of natural and combinatorial anti-PDC-E2 antibodies in patients with primary biliary cirrhosis: Recapitulating immune selection with molecular biology
    • Pascual, V., Cha, S., Gershwin, M. E., Capra, J. D. & Leung, P. S. C. (1994). Nucleotide sequence analysis of natural and combinatorial anti-PDC-E2 antibodies in patients with primary biliary cirrhosis: recapitulating immune selection with molecular biology. J. Immunol. 153, 2577-2585.
    • (1994) J. Immunol. , vol.153 , pp. 2577-2585
    • Pascual, V.1    Cha, S.2    Gershwin, M.E.3    Capra, J.D.4    Leung, P.S.C.5
  • 46
    • 0027153974 scopus 로고
    • Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette"
    • Portolano, S., Chazenbalk, G. D., Hutchison, J. S., McLachlan, S. M., & Rapoport, B. (1993). Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette". J. Immunol. 150, 880-887.
    • (1993) J. Immunol. , vol.150 , pp. 880-887
    • Portolano, S.1    Chazenbalk, G.D.2    Hutchison, J.S.3    McLachlan, S.M.4    Rapoport, B.5
  • 49
    • 0025942329 scopus 로고
    • Molecular characterisation of a supratypic cross-reactive idiotype associated with IgM autoantibodies
    • Pratt, L. F., Szubin, R., Carson, D. A. & Kipps, T. J. (1991). Molecular characterisation of a supratypic cross-reactive idiotype associated with IgM autoantibodies. J. Immunol. 147, 2041-2046.
    • (1991) J. Immunol. , vol.147 , pp. 2041-2046
    • Pratt, L.F.1    Szubin, R.2    Carson, D.A.3    Kipps, T.J.4
  • 50
    • 0015972878 scopus 로고
    • Clinical and immunochemical studies of IgM cold agglutinins with lambda type light chains
    • Pruzanski, W., Cowan, D. H. & Parr, D. M. (1974). Clinical and immunochemical studies of IgM cold agglutinins with lambda type light chains. Clin. Immunol. Immunopathol. 2, 234-245.
    • (1974) Clin. Immunol. Immunopathol. , vol.2 , pp. 234-245
    • Pruzanski, W.1    Cowan, D.H.2    Parr, D.M.3
  • 51
    • 0021158396 scopus 로고
    • Cold agglutinins: Antibodies with biological diversity
    • Pruzanski, W. & Katz, A. (1984). Cold agglutinins: antibodies with biological diversity. Clin. Immunol. Rev. 3, 131-150.
    • (1984) Clin. Immunol. Rev. , vol.3 , pp. 131-150
    • Pruzanski, W.1    Katz, A.2
  • 52
    • 0026029759 scopus 로고
    • Ig H and L chain contributions to autoimmune specificities
    • Radic, M. Z., Mascelli, M. A., Erikson, J., Shan, H. & Weigert, M. (1991). Ig H and L chain contributions to autoimmune specificities. J. Immunol. 140, 176-182.
    • (1991) J. Immunol. , vol.140 , pp. 176-182
    • Radic, M.Z.1    Mascelli, M.A.2    Erikson, J.3    Shan, H.4    Weigert, M.5
  • 55
    • 0023934039 scopus 로고
    • Human naive and memory T cells: Reinterpretation of helper-inducer and suppressor-inducer subsets
    • Sanders, M. E., Makgoba, M. W. & Shaw, S. (1988). Human naive and memory T cells: reinterpretation of helper-inducer and suppressor-inducer subsets. Immunol. Today, 9, 195-199.
    • (1988) Immunol. Today , vol.9 , pp. 195-199
    • Sanders, M.E.1    Makgoba, M.W.2    Shaw, S.3
  • 56
    • 0019162146 scopus 로고
    • Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing
    • Sanger, F., Carlson, A. R., Barrel, B. G., Smith, A. J. H. & Roe, B. (1980). Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J. Mol. Biol. 143, 161-178.
    • (1980) J. Mol. Biol. , vol.143 , pp. 161-178
    • Sanger, F.1    Carlson, A.R.2    Barrel, B.G.3    Smith, A.J.H.4    Roe, B.5
  • 57
    • 0023123378 scopus 로고
    • Vκ and Jκ gene segments of A/J Ars-A antibodies: Somatic recombination generates the essential arginine at the junction of the variable and joining regions
    • Sanz, I. & Capra, J. D. (1987). Vκ and Jκ gene segments of A/J Ars-A antibodies: somatic recombination generates the essential arginine at the junction of the variable and joining regions. Proc. Natl Acad. Sci. USA, 84, 1085-1089.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 1085-1089
    • Sanz, I.1    Capra, J.D.2
  • 58
    • 0028223116 scopus 로고
    • Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions
    • Sato, K., Tsuchiya, M., Saldanha, J., Koishihara, Y., Ohsugi, Y., Kishimoto, T. & Bendig, M. M. (1994). Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions. Mol. Immunol. 31, 371-381.
    • (1994) Mol. Immunol. , vol.31 , pp. 371-381
    • Sato, K.1    Tsuchiya, M.2    Saldanha, J.3    Koishihara, Y.4    Ohsugi, Y.5    Kishimoto, T.6    Bendig, M.M.7
  • 59
    • 0022441434 scopus 로고
    • Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells
    • Schlomchik, M. J., Nemazee, D. A., Sato, V. L., Van Snick, J., Carson, D. A. & Weigert, M. G. (1986). Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. J. Expt. Med. 164, 407-427.
    • (1986) J. Expt. Med. , vol.164 , pp. 407-427
    • Schlomchik, M.J.1    Nemazee, D.A.2    Sato, V.L.3    Van Snick, J.4    Carson, D.A.5    Weigert, M.G.6
  • 60
    • 0027333555 scopus 로고
    • H4.21-encoded natural autoantibodies with anti-i specificity mirror those associated with cold hemagglutinin disease
    • H4.21-encoded natural autoantibodies with anti-i specificity mirror those associated with cold hemagglutinin disease. J. Immunol. 151, 6569-6576.
    • (1993) J. Immunol. , vol.151 , pp. 6569-6576
    • Schutte, M.E.M.1    Van Es, J.H.2    Silberstein, L.E.3    Logtenberg, T.4
  • 63
    • 0027268489 scopus 로고
    • Natural and pathologic human autoimmune responses to carbohydrate antigens on red blood cells
    • Silberstein, L. E. (1993). Natural and pathologic human autoimmune responses to carbohydrate antigens on red blood cells. Springer Semin. Immunopathol. 15, 139-153.
    • (1993) Springer Semin. Immunopathol. , vol.15 , pp. 139-153
    • Silberstein, L.E.1
  • 67
    • 0024604730 scopus 로고
    • Identificaction of normal B-cell counterparts of neoplastic cells which secrete cold agglutinins of anti-I and anti-i specificity
    • Stevenson, F. K., Smith, G. J., North, J., Hamblin, T. J. & Glennie, M. J. (1989). Identificaction of normal B-cell counterparts of neoplastic cells which secrete cold agglutinins of anti-I and anti-i specificity. Brit. J. Haematol. 72, 9-15.
    • (1989) Brit. J. Haematol. , vol.72 , pp. 9-15
    • Stevenson, F.K.1    Smith, G.J.2    North, J.3    Hamblin, T.J.4    Glennie, M.J.5
  • 68
    • 0028908879 scopus 로고
    • Striking inverse correlation between IgG anti-F(ab′)2 and autoantibody production in patients with cold agglutination
    • Terness, P., Kirschfink, M., Navolan, D., Dufter, C., Kohl, I., Opetz, G., & Roelcke, D. (1995). Striking inverse correlation between IgG anti-F(ab′)2 and autoantibody production in patients with cold agglutination. Blood, 85, 548-551.
    • (1995) Blood , vol.85 , pp. 548-551
    • Terness, P.1    Kirschfink, M.2    Navolan, D.3    Dufter, C.4    Kohl, I.5    Opetz, G.6    Roelcke, D.7
  • 70
    • 0026645402 scopus 로고
    • Human monoclonal antibodies specific for blood group antigens demonstrate multispecific properties characteristic of natural autoantibodies
    • Thompson, K. M., Sutherland, J., Barden, G., Melamed, M. D., Wright, M. G., Bailey, S. & Thorpe, S. J. (1992). Human monoclonal antibodies specific for blood group antigens demonstrate multispecific properties characteristic of natural autoantibodies. Immunol. 76, 146-157.
    • (1992) Immunol. , vol.76 , pp. 146-157
    • Thompson, K.M.1    Sutherland, J.2    Barden, G.3    Melamed, M.D.4    Wright, M.G.5    Bailey, S.6    Thorpe, S.J.7
  • 71
    • 0025978752 scopus 로고
    • Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus
    • van Es, J., Meyling, F. H. J. G., van de Akker, W., Aanstoot, H., Derksin, R. H. W. M. & Logtenberg, T. (1991). Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus. J. Expt. Med. 173, 461-470.
    • (1991) J. Expt. Med. , vol.173 , pp. 461-470
    • Van Es, J.1    Meyling, F.H.J.G.2    Van De Akker, W.3    Aanstoot, H.4    Derksin, R.H.W.M.5    Logtenberg, T.6
  • 73
    • 0025763929 scopus 로고
    • Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po and Bla cross-reactive idiotypes
    • Victor, K. D., Randen, I., Thompson, K., Forre, O., Natvig, J. B., Fu, S-M. & Capra, J. D. (1991). Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po and Bla cross-reactive idiotypes. J. Clin. Invest. 87, 1603-1613.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1603-1613
    • Victor, K.D.1    Randen, I.2    Thompson, K.3    Forre, O.4    Natvig, J.B.5    Fu, S.-M.6    Capra, J.D.7
  • 74
    • 0026466049 scopus 로고
    • Human anti-acetylcholine receptor antibodies use variable gene segments analogous to those used in autoantibodies of various specificities
    • Victor, K. D., Pascual, V., Lefvert, A. K. & Capra, J. D. (1992). Human anti-acetylcholine receptor antibodies use variable gene segments analogous to those used in autoantibodies of various specificities. Mol. Immunol. 29, 1501-1506.
    • (1992) Mol. Immunol. , vol.29 , pp. 1501-1506
    • Victor, K.D.1    Pascual, V.2    Lefvert, A.K.3    Capra, J.D.4
  • 75
    • 0014430976 scopus 로고
    • Antigenic specificities related to the cold agglutinin activity of gamma m globulins
    • Williams, R. C., Kunkel, H. G. & Capra, J. D. (1968). Antigenic specificities related to the cold agglutinin activity of gamma M globulins. Science, 161, 379-381.
    • (1968) Science , vol.161 , pp. 379-381
    • Williams, R.C.1    Kunkel, H.G.2    Capra, J.D.3
  • 76
    • 0026629492 scopus 로고
    • Possible use of similar framework region amino acid sequences between human and mouse immunoglobulins for humanizing mouse antibodies
    • Wu, T. T. & Kabat, E. A. (1992). Possible use of similar framework region amino acid sequences between human and mouse immunoglobulins for humanizing mouse antibodies. Mol. Immunol. 29, 1141-1146.
    • (1992) Mol. Immunol. , vol.29 , pp. 1141-1146
    • Wu, T.T.1    Kabat, E.A.2
  • 77
    • 0025727162 scopus 로고
    • Modification in framework region 1 results in a decreased affinity of chimeric anti-TAG72 antibody
    • Xiang, J., Roder, J., Pan, Z., Rooifman, C. & Hozumi, N. (1991). Modification in framework region 1 results in a decreased affinity of chimeric anti-TAG72 antibody. Mol. Immunol. 28, 141-148.
    • (1991) Mol. Immunol. , vol.28 , pp. 141-148
    • Xiang, J.1    Roder, J.2    Pan, Z.3    Rooifman, C.4    Hozumi, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.