-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144(5), 646-74.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg R., .A.2
-
2
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast. 1889
-
2673568 1:STN:280:DyaL1Mzns1OmsA%3D%3D
-
Paget, S. (1989). The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Reviews, 8(2), 98-101.
-
(1989)
Cancer Metastasis Reviews
, vol.8
, Issue.2
, pp. 98-101
-
-
Paget, S.1
-
3
-
-
0019983407
-
Evidence for the clonal origin of spontaneous metastases
-
6953592 1:STN:280:DyaL383itlyisg%3D%3D
-
Talmadge, J. E.; Wolman, S. R.; & Fidler, I. J. (1982). Evidence for the clonal origin of spontaneous metastases. Science, 217(4557), 361-363.
-
(1982)
Science
, vol.217
, Issue.4557
, pp. 361-363
-
-
Talmadge, J.E.1
Wolman, S.R.2
Fidler, I.J.3
-
4
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
15210113 1:CAS:528:DC%2BD2cXlsFWnu7w%3D
-
Yang, J.; et al. (2004). Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell, 117(7), 927-939.
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
-
5
-
-
0036984640
-
Role of angiogenesis in tumor growth and metastasis
-
12516034 1:CAS:528:DC%2BD3sXlvFSqtg%3D%3D
-
Folkman, J. (2002). Role of angiogenesis in tumor growth and metastasis. Seminars in Oncology, 29(6 Suppl 16), 15-18.
-
(2002)
Seminars in Oncology
, vol.29
, Issue.6 SUPPL. 16
, pp. 15-18
-
-
Folkman, J.1
-
6
-
-
82255165125
-
Tumor immune escape mechanisms that operate during metastasis
-
Croci, D. O.; & Salatino M. (2011). Tumor immune escape mechanisms that operate during metastasis. Current Pharmaceutical Biotechnology, 12(11), 1923-1936.
-
(2011)
Current Pharmaceutical Biotechnology
, vol.12
, Issue.11
, pp. 1923-1936
-
-
Croci D., .O.1
Salatino, M.2
-
7
-
-
33751328082
-
ErbB receptors: New insights on mechanisms and biology
-
17085050 1:CAS:528:DC%2BD28Xht1OhtLnM
-
Linggi, B.; & Carpenter, G. (2006). ErbB receptors: New insights on mechanisms and biology. Trends in Cell Biology, 16(12), 649-656.
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.12
, pp. 649-656
-
-
Linggi, B.1
Carpenter, G.2
-
8
-
-
0024203849
-
Growth effects of epidermal growth factor (EGF) and a monoclonal antibody against the EGF receptor on four glioma cell lines
-
3265834 1:CAS:528:DyaL1MXovFChtg%3D%3D
-
Werner, M. H.; et al. (1988). Growth effects of epidermal growth factor (EGF) and a monoclonal antibody against the EGF receptor on four glioma cell lines. Acta Neuropathologica, 77(2), 196-201.
-
(1988)
Acta Neuropathologica
, vol.77
, Issue.2
, pp. 196-201
-
-
Werner, M.H.1
-
9
-
-
0023595325
-
Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene
-
3500513 1:CAS:528:DyaL1cXjt12ktg%3D%3D
-
Velu, T. J.; et al. (1987). Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene. Science, 238(4832), 1408-1410.
-
(1987)
Science
, vol.238
, Issue.4832
, pp. 1408-1410
-
-
Velu, T.J.1
-
10
-
-
0023663896
-
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
-
3500791
-
Di Fiore, P. P.; et al. (1987). Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell, 51(6), 1063-1070.
-
(1987)
Cell
, vol.51
, Issue.6
, pp. 1063-1070
-
-
Di Fiore, P.P.1
-
11
-
-
0023279839
-
Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer
-
2884496 1:STN:280:DyaL2s3islOqtw%3D%3D
-
Sainsbury, J. R.; et al. (1987). Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer. Lancet, 1(8547), 1398-1402.
-
(1987)
Lancet
, vol.1
, Issue.8547
, pp. 1398-1402
-
-
Sainsbury, J.R.1
-
12
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
3477813 1:CAS:528:DyaL1cXktVyq
-
Wong, A. J.; et al. (1987). Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proceedings of the National Academy of Sciences of the United States of America, 84(19), 6899-6903.
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.19
, pp. 6899-6903
-
-
Wong, A.J.1
-
13
-
-
0023261096
-
Epidermal growth factor receptors in non-small cell lung cancer
-
3038157 1:STN:280:DyaL2s3ntFClsQ%3D%3D
-
Veale, D.; et al. (1987). Epidermal growth factor receptors in non-small cell lung cancer. British Journal of Cancer, 55(5), 513-516.
-
(1987)
British Journal of Cancer
, vol.55
, Issue.5
, pp. 513-516
-
-
Veale, D.1
-
14
-
-
0035018353
-
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase
-
11359909 1:CAS:528:DC%2BD3MXktFWgtLw%3D
-
Lu, Z.; et al. (2001). Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Molecular and Cellular Biology, 21(12), 4016-4031.
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.12
, pp. 4016-4031
-
-
Lu, Z.1
-
15
-
-
0345736990
-
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion
-
14706341 1:CAS:528:DC%2BD2cXitFOjtw%3D%3D
-
Lu, Z.; et al. (2003). Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell, 4(6), 499-515.
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 499-515
-
-
Lu, Z.1
-
16
-
-
20144386716
-
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities
-
15719014 1:CAS:528:DC%2BD2MXitV2itrs%3D
-
Onodera, Y.; et al. (2005). Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. EMBO Journal, 24(5), 963-973.
-
(2005)
EMBO Journal
, vol.24
, Issue.5
, pp. 963-973
-
-
Onodera, Y.1
-
17
-
-
84861679836
-
EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation
-
Huang, M.; et al. (2012). EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene, 31, 2783-2793.
-
(2012)
Oncogene
, vol.31
, pp. 2783-2793
-
-
Huang, M.1
-
18
-
-
44949117528
-
Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells
-
1:CAS:528:DC%2BD1cXnsF2jsbY%3D
-
Ueno, Y.; et al. (2008). Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells. International Journal of Cancer, 123(2), 340-347.
-
(2008)
International Journal of Cancer
, vol.123
, Issue.2
, pp. 340-347
-
-
Ueno, Y.1
-
19
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
16049480 1:CAS:528:DC%2BD2MXmsFCgs7o%3D
-
Minn, A. J.; et al. (2005). Genes that mediate breast cancer metastasis to lung. Nature, 436(7050), 518-524.
-
(2005)
Nature
, vol.436
, Issue.7050
, pp. 518-524
-
-
Minn, A.J.1
-
20
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
19421193 1:CAS:528:DC%2BD1MXlsVKksLc%3D
-
Bos, P. D.; et al. (2009). Genes that mediate breast cancer metastasis to the brain. Nature, 459(7249), 1005-1009.
-
(2009)
Nature
, vol.459
, Issue.7249
, pp. 1005-1009
-
-
Bos, P.D.1
-
21
-
-
34548118196
-
The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells
-
17601710 1:CAS:528:DC%2BD2sXpsFKhs7c%3D
-
Guo, Z.; et al. (2007). The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells. Colloids and Surfaces. B, Biointerfaces, 60(1), 1-6.
-
(2007)
Colloids and Surfaces. B, Biointerfaces
, vol.60
, Issue.1
, pp. 1-6
-
-
Guo, Z.1
-
22
-
-
36749003738
-
Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma
-
1:CAS:528:DC%2BD2sXhsVSgtb3N
-
Kajiyama, H.; et al. (2008). Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. International Journal of Cancer, 122(1), 91-99.
-
(2008)
International Journal of Cancer
, vol.122
, Issue.1
, pp. 91-99
-
-
Kajiyama, H.1
-
23
-
-
0026659262
-
Identification of heregulin, a specific activator of p185erbB2
-
1350381 1:CAS:528:DyaK3sXitFSgt70%3D
-
Holmes, W. E.; et al. (1992). Identification of heregulin, a specific activator of p185erbB2. Science, 256(5060), 1205-1210.
-
(1992)
Science
, vol.256
, Issue.5060
, pp. 1205-1210
-
-
Holmes, W.E.1
-
24
-
-
0026700010
-
Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses
-
1349015 1:CAS:528:DyaK38Xit1ynsrg%3D
-
Spivak-Kroizman, T.; et al. (1992). Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. Journal of Biological Chemistry, 267(12), 8056-8063.
-
(1992)
Journal of Biological Chemistry
, vol.267
, Issue.12
, pp. 8056-8063
-
-
Spivak-Kroizman, T.1
-
25
-
-
0037931402
-
Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: Distribution of homo- and heterodimers depends on relative HER2 levels
-
12686539 1:CAS:528:DC%2BD3sXkslygs7k%3D
-
Hendriks, B. S.; et al. (2003). Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: Distribution of homo- and heterodimers depends on relative HER2 levels. Journal of Biological Chemistry, 278(26), 23343-23351.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 23343-23351
-
-
Hendriks, B.S.1
-
26
-
-
0024976405
-
Neu receptor dimerization
-
2567498 1:CAS:528:DyaL1MXkvFanurc%3D
-
Sternberg, M. J.; & Gullick, W. J. (1989). Neu receptor dimerization. Nature, 339(6226), 587.
-
(1989)
Nature
, vol.339
, Issue.6226
, pp. 587
-
-
Sternberg, M.J.1
Gullick, W.J.2
-
27
-
-
0023618780
-
Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis
-
3330785 1:STN:280:DyaL1c3mt1agtQ%3D%3D
-
Varley, J. M.; et al. (1987). Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis. Oncogene, 1(4), 423-430.
-
(1987)
Oncogene
, vol.1
, Issue.4
, pp. 423-430
-
-
Varley, J.M.1
-
28
-
-
0023124598
-
Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene
-
3299059
-
van de Vijver, M.; et al. (1987). Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene. Molecular and Cellular Biology, 7(5), 2019-2023.
-
(1987)
Molecular and Cellular Biology
, vol.7
, Issue.5
, pp. 2019-2023
-
-
Van De Vijver, M.1
-
29
-
-
0024259860
-
Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: Correlation with poor prognosis
-
2905033 1:STN:280:DyaL1M%2Fotlajug%3D%3D
-
Guerin, M.; et al. (1988). Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: Correlation with poor prognosis. Oncogene Research, 3(1), 21-31.
-
(1988)
Oncogene Research
, vol.3
, Issue.1
, pp. 21-31
-
-
Guerin, M.1
-
30
-
-
0025662028
-
Neu (C-erbB-2) oncogene in breast cancer and its possible association with the risk of distant metastases. A retrospective study and review of literature
-
1979748 1:STN:280:DyaK3M%2FosVShsw%3D%3D
-
Makar, A. P.; et al. (1990). Neu (C-erbB-2) oncogene in breast cancer and its possible association with the risk of distant metastases. A retrospective study and review of literature. Acta Oncologica, 29(7), 931-934.
-
(1990)
Acta Oncologica
, vol.29
, Issue.7
, pp. 931-934
-
-
Makar, A.P.1
-
31
-
-
0025940263
-
Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells
-
1682865 1:CAS:528:DyaK38XhvFSlug%3D%3D
-
Yu, D. H.; & Hung, M. C. (1991). Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells. Oncogene, 6(11), 1991-1996.
-
(1991)
Oncogene
, vol.6
, Issue.11
, pp. 1991-1996
-
-
Yu, D.H.1
Hung, M.C.2
-
32
-
-
0026443229
-
Mechanisms of c-erbB2/neu oncogene-induced metastasis and repression of metastatic properties by adenovirus 5 E1A gene products
-
1359495 1:CAS:528:DyaK3sXmt1ejtrY%3D
-
Yu, D.; et al. (1992). Mechanisms of c-erbB2/neu oncogene-induced metastasis and repression of metastatic properties by adenovirus 5 E1A gene products. Oncogene, 7(11), 2263-2270.
-
(1992)
Oncogene
, vol.7
, Issue.11
, pp. 2263-2270
-
-
Yu, D.1
-
33
-
-
0028278501
-
C-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties
-
7911396 1:CAS:528:DyaK2cXksFCqsr0%3D
-
Yu, D.; et al. (1994). c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties. Cancer Research, 54(12), 3260-3266.
-
(1994)
Cancer Research
, vol.54
, Issue.12
, pp. 3260-3266
-
-
Yu, D.1
-
34
-
-
0030059213
-
Transfected neu oncogene induces human prostate cancer metastasis
-
8604395 1:CAS:528:DyaK28Xhslyntr4%3D
-
Zhau, H. Y.; et al. (1996). Transfected neu oncogene induces human prostate cancer metastasis. Prostate, 28(2), 73-83.
-
(1996)
Prostate
, vol.28
, Issue.2
, pp. 73-83
-
-
Zhau, H.Y.1
-
35
-
-
19044370434
-
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
-
12498714 1:CAS:528:DC%2BD3sXht1ylsA%3D%3D
-
Moody, S. E.; et al. (2002). Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. Cancer Cell, 2(6), 451-461.
-
(2002)
Cancer Cell
, vol.2
, Issue.6
, pp. 451-461
-
-
Moody, S.E.1
-
36
-
-
33646169430
-
HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion
-
16377629 1:CAS:528:DC%2BD28Xhs1eksrc%3D
-
Hsu, M. C.; Chang, H. C.; & Hung, W. C. (2006). HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. Journal of Biological Chemistry, 281(8), 4718-4725.
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.8
, pp. 4718-4725
-
-
Hsu, M.C.1
Chang, H.C.2
Hung, W.C.3
-
37
-
-
67649234062
-
A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis
-
19364815 1:CAS:528:DC%2BD1MXnt1Ggu70%3D
-
Pedersen, K.; et al. (2009). A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis. Molecular and Cellular Biology, 29(12), 3319-3331.
-
(2009)
Molecular and Cellular Biology
, vol.29
, Issue.12
, pp. 3319-3331
-
-
Pedersen, K.1
-
38
-
-
33644529055
-
ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells
-
16489002 1:CAS:528:DC%2BD28XhsFamu78%3D
-
Klos, K. S.; et al. (2006). ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells. Cancer Research, 66(4), 2028-2037.
-
(2006)
Cancer Research
, vol.66
, Issue.4
, pp. 2028-2037
-
-
Klos, K.S.1
-
39
-
-
7944223780
-
Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis
-
15542430 1:CAS:528:DC%2BD2cXhtVGlurvF
-
Li, Y. M.; et al. (2004). Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell, 6(5), 459-469.
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 459-469
-
-
Li, Y.M.1
-
40
-
-
0024523622
-
Tyrosine kinase receptor indistinguishable from the c-met protein
-
2541345 1:CAS:528:DyaL1MXkslenu7s%3D
-
Giordano, S.; et al. (1989). Tyrosine kinase receptor indistinguishable from the c-met protein. Nature, 339(6220), 155-156.
-
(1989)
Nature
, vol.339
, Issue.6220
, pp. 155-156
-
-
Giordano, S.1
-
41
-
-
0017773394
-
The use of limovanil in pregnancy
-
846706 1:STN:280:DyaE2s7kslyktQ%3D%3D
-
Gardo, S. (1977). The use of limovanil in pregnancy. Orvosi Hetilap, 118(11), 660.
-
(1977)
Orvosi Hetilap
, vol.118
, Issue.11
, pp. 660
-
-
Gardo, S.1
-
42
-
-
0025788025
-
The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase
-
1718989 1:CAS:528:DyaK3MXmslCgs70%3D
-
Graziani, A.; et al. (1991). The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase. Journal of Biological Chemistry, 266(33), 22087-22090.
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.33
, pp. 22087-22090
-
-
Graziani, A.1
-
43
-
-
38549115197
-
The Met tyrosine kinase receptor in development and cancer
-
18175071 1:CAS:528:DC%2BD1cXhtV2gu74%3D
-
Gentile, A.; Trusolino, L.; & Comoglio, P. M. (2008). The Met tyrosine kinase receptor in development and cancer. Cancer Metastasis Reviews, 27(1), 85-94.
-
(2008)
Cancer Metastasis Reviews
, vol.27
, Issue.1
, pp. 85-94
-
-
Gentile, A.1
Trusolino, L.2
Comoglio, P.M.3
-
44
-
-
0028276786
-
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation
-
8197126 1:CAS:528:DyaK2cXktlahs7Y%3D
-
Rong, S.; et al. (1994). Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proceedings of the National Academy of Sciences of the United States of America, 91(11), 4731-4735.
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.11
, pp. 4731-4735
-
-
Rong, S.1
-
45
-
-
0032558793
-
Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis
-
9798673 1:CAS:528:DyaK1cXnt1Glt7g%3D
-
Webb, C. P.; et al. (1998). Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis. Oncogene, 17(16), 2019-2025.
-
(1998)
Oncogene
, vol.17
, Issue.16
, pp. 2019-2025
-
-
Webb, C.P.1
-
46
-
-
0035845485
-
Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase
-
11535809 1:CAS:528:DC%2BD3MXntVGmsrc%3D
-
Furge, K. A.; et al. (2001). Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America, 98(19), 10722-10727.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10722-10727
-
-
Furge, K.A.1
-
47
-
-
72949083968
-
Co-overexpression of Met and hepatocyte growth factor promotes systemic metastasis in NCI-H460 non-small cell lung carcinoma cells
-
20019837 1:CAS:528:DC%2BD1MXhsFejurjI
-
Navab, R.; et al. (2009). Co-overexpression of Met and hepatocyte growth factor promotes systemic metastasis in NCI-H460 non-small cell lung carcinoma cells. Neoplasia, 11(12), 1292-1300.
-
(2009)
Neoplasia
, vol.11
, Issue.12
, pp. 1292-1300
-
-
Navab, R.1
-
48
-
-
0031471232
-
A point mutation in the MET oncogene abrogates metastasis without affecting transformation
-
9391119 1:CAS:528:DyaK2sXotVart7Y%3D
-
Giordano, S.; et al. (1997). A point mutation in the MET oncogene abrogates metastasis without affecting transformation. Proceedings of the National Academy of Sciences of the United States of America, 94(25), 13868-13872.
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.25
, pp. 13868-13872
-
-
Giordano, S.1
-
49
-
-
0033521924
-
Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis
-
10022119 1:CAS:528:DyaK1MXhsVykt7c%3D
-
Bardelli, A.; et al. (1999). Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis. Oncogene, 18(5), 1139-1146.
-
(1999)
Oncogene
, vol.18
, Issue.5
, pp. 1139-1146
-
-
Bardelli, A.1
-
50
-
-
77952581424
-
Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and beta-catenin/Wnt pathways
-
Previdi, S.; et al. (2010). Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and beta-catenin/Wnt pathways. European Journal of Cancer, 46(9), 1679-1691.
-
(2010)
European Journal of Cancer
, vol.46
, Issue.9
, pp. 1679-1691
-
-
Previdi, S.1
-
51
-
-
84855675936
-
Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown
-
Previdi, S.; et al. (2011). Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown. Molecular Cancer Therapeutics, 11(1), 214-223.
-
(2011)
Molecular Cancer Therapeutics
, vol.11
, Issue.1
, pp. 214-223
-
-
Previdi, S.1
-
52
-
-
4344694684
-
Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor
-
15221009 1:CAS:528:DC%2BD2cXmslCmtLw%3D
-
Dong, G.; et al. (2004). Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor. Oncogene, 23(37), 6199-6208.
-
(2004)
Oncogene
, vol.23
, Issue.37
, pp. 6199-6208
-
-
Dong, G.1
-
53
-
-
0030039519
-
Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network
-
8622656 1:CAS:528:DyaK28XhtFOls7k%3D
-
Jeffers, M.; Rong, S.; & Vande Woude, G. F. (1996). Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network. Molecular and Cellular Biology, 16(3), 1115-1125.
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.3
, pp. 1115-1125
-
-
Jeffers, M.1
Rong, S.2
Vande Woude, G.F.3
-
54
-
-
0033999314
-
Disassociation of met-mediated biological responses in vivo: The natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis
-
10688652 1:CAS:528:DC%2BD3cXhsVKmsb0%3D
-
Otsuka, T.; et al. (2000). Disassociation of met-mediated biological responses in vivo: The natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis. Molecular and Cellular Biology, 20(6), 2055-2065.
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.6
, pp. 2055-2065
-
-
Otsuka, T.1
-
55
-
-
0037093106
-
Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model
-
12019177 1:CAS:528:DC%2BD38XjvFSmtLk%3D
-
Yu, Y.; & Merlino, G. (2002). Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model. Cancer Research, 62(10), 2951-2956.
-
(2002)
Cancer Research
, vol.62
, Issue.10
, pp. 2951-2956
-
-
Yu, Y.1
Merlino, G.2
-
56
-
-
0031685620
-
TGF-beta signal transduction
-
9759503 1:CAS:528:DyaK1cXlsFOmsbY%3D
-
Massague, J. (1998). TGF-beta signal transduction. Annual Review of Biochemistry, 67, 753-791.
-
(1998)
Annual Review of Biochemistry
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
57
-
-
78649982907
-
The dynamic roles of TGF-beta in cancer
-
Meulmeester, E.; & Ten Dijke, P. (2011). The dynamic roles of TGF-beta in cancer. Journal of Pathology, 223(2), 205-218.
-
(2011)
Journal of Pathology
, vol.223
, Issue.2
, pp. 205-218
-
-
Meulmeester, E.1
Ten Dijke, P.2
-
58
-
-
25444479744
-
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
-
16172383 1:CAS:528:DC%2BD2MXhtVOqsbjM
-
Kang, Y.; et al. (2005). Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proceedings of the National Academy of Sciences of the United States of America, 102(39), 13909-13914.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.39
, pp. 13909-13914
-
-
Kang, Y.1
-
59
-
-
33644534795
-
The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells
-
16489022 1:CAS:528:DC%2BD28XhsFals78%3D
-
Deckers, M.; et al. (2006). The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells. Cancer Research, 66(4), 2202-2209.
-
(2006)
Cancer Research
, vol.66
, Issue.4
, pp. 2202-2209
-
-
Deckers, M.1
-
60
-
-
33746145265
-
Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type i receptor kinase inhibitor
-
16818646 1:CAS:528:DC%2BD28XmsVamu7o%3D
-
Bandyopadhyay, A.; et al. (2006). Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor. Cancer Research, 66(13), 6714-6721.
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6714-6721
-
-
Bandyopadhyay, A.1
-
61
-
-
68349160814
-
Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis
-
19597504 1:CAS:528:DC%2BD1MXosFWhtr0%3D
-
Korpal, M.; et al. (2009). Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. Nature Medicine, 15(8), 960-966.
-
(2009)
Nature Medicine
, vol.15
, Issue.8
, pp. 960-966
-
-
Korpal, M.1
-
62
-
-
77952609184
-
Targeting the transforming growth factor-beta pathway inhibits human basal-like breast cancer metastasis
-
Ganapathy, V.; et al. (2010). Targeting the transforming growth factor-beta pathway inhibits human basal-like breast cancer metastasis. Molecular Cancer, 9, 122.
-
(2010)
Molecular Cancer
, vol.9
, pp. 122
-
-
Ganapathy, V.1
-
63
-
-
80855128847
-
Anti-transforming growth factor ss antibody treatment rescues bone loss and prevents breast cancer metastasis to bone
-
Biswas, S.; et al. (2011). Anti-transforming growth factor ss antibody treatment rescues bone loss and prevents breast cancer metastasis to bone. PLoS One, 6(11), e27090.
-
(2011)
PLoS One
, vol.6
, Issue.11
-
-
Biswas, S.1
-
64
-
-
79551514021
-
TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling
-
Johnson, R. W.; et al. (2011). TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling. Cancer Research, 71(3), 822-831.
-
(2011)
Cancer Research
, vol.71
, Issue.3
, pp. 822-831
-
-
Johnson, R.W.1
-
65
-
-
77949265948
-
Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
-
Petersen, M.; et al. (2009). Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis. Oncogene, 29(9), 1351-1361.
-
(2009)
Oncogene
, vol.29
, Issue.9
, pp. 1351-1361
-
-
Petersen, M.1
-
66
-
-
33845947297
-
TGF-beta promotes the establishment of renal cell carcinoma bone metastasis
-
17032147 1:CAS:528:DC%2BD2sXhtVWntbg%3D
-
Kominsky, S. L.; et al. (2007). TGF-beta promotes the establishment of renal cell carcinoma bone metastasis. Journal of Bone and Mineral Research, 22(1), 37-44.
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.1
, pp. 37-44
-
-
Kominsky, S.L.1
-
67
-
-
57049115389
-
MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-beta1
-
1:CAS:528:DC%2BD1MXht1yqsb0%3D
-
Kominsky, S. L.; et al. (2008). MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-beta1. Clinical & Experimental Metastasis, 25(8), 865-870.
-
(2008)
Clinical & Experimental Metastasis
, vol.25
, Issue.8
, pp. 865-870
-
-
Kominsky, S.L.1
-
68
-
-
0029615462
-
Anti-(transforming growth factor beta) antibodies with predefined specificity inhibit metastasis of highly tumorigenic human xenotransplants in nu/nu mice
-
8536276 1:CAS:528:DyaK28Xhtlymsbo%3D
-
Hoefer, M.; & Anderer, F. A. (1995). Anti-(transforming growth factor beta) antibodies with predefined specificity inhibit metastasis of highly tumorigenic human xenotransplants in nu/nu mice. Cancer Immunology, Immunotherapy, 41(5), 302-308.
-
(1995)
Cancer Immunology, Immunotherapy
, vol.41
, Issue.5
, pp. 302-308
-
-
Hoefer, M.1
Anderer, F.A.2
-
69
-
-
59149102419
-
Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain
-
19141644 1:CAS:528:DC%2BD1MXhtFOktrk%3D
-
Zhang, C.; et al. (2009). Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain. Cancer Research, 69(3), 828-835.
-
(2009)
Cancer Research
, vol.69
, Issue.3
, pp. 828-835
-
-
Zhang, C.1
-
70
-
-
79955862101
-
TGF-beta1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells
-
Pakala, S. B.; et al. (2011). TGF-beta1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells. Oncogene, 30(19), 2230-2241.
-
(2011)
Oncogene
, vol.30
, Issue.19
, pp. 2230-2241
-
-
Pakala, S.B.1
-
71
-
-
0035902805
-
Enhanced VEGF production and decreased immunogenicity induced by TGF-beta 1 promote liver metastasis of pancreatic cancer
-
11506504 1:CAS:528:DC%2BD3MXmvFKks7s%3D
-
Teraoka, H.; et al. (2001). Enhanced VEGF production and decreased immunogenicity induced by TGF-beta 1 promote liver metastasis of pancreatic cancer. British Journal of Cancer, 85(4), 612-617.
-
(2001)
British Journal of Cancer
, vol.85
, Issue.4
, pp. 612-617
-
-
Teraoka, H.1
-
72
-
-
0035486830
-
TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion
-
11562745 1:CAS:528:DC%2BD3MXnsFSmtbY%3D
-
Teraoka, H.; et al. (2001). TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion. International Journal of Oncology, 19(4), 709-715.
-
(2001)
International Journal of Oncology
, vol.19
, Issue.4
, pp. 709-715
-
-
Teraoka, H.1
-
73
-
-
34347400681
-
TGF-beta1 down-regulates ICAM-1 expression and enhances liver metastasis of pancreatic cancer
-
17357279 1:CAS:528:DC%2BD2sXitlais74%3D
-
Sawada, T.; et al. (2006). TGF-beta1 down-regulates ICAM-1 expression and enhances liver metastasis of pancreatic cancer. Advances in Medical Sciences, 51, 60-65.
-
(2006)
Advances in Medical Sciences
, vol.51
, pp. 60-65
-
-
Sawada, T.1
-
74
-
-
42249099019
-
LY2109761, a novel transforming growth factor beta receptor type i and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
-
18413796 1:CAS:528:DC%2BD1cXks1GmsL4%3D
-
Melisi, D.; et al. (2008). LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. Molecular Cancer Therapeutics, 7(4), 829-840.
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.4
, pp. 829-840
-
-
Melisi, D.1
-
75
-
-
0035887461
-
Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis
-
11606377 1:CAS:528:DC%2BD3MXnvFShsL4%3D
-
Weeks, B. H.; et al. (2001). Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis. Cancer Research, 61(20), 7435-7443.
-
(2001)
Cancer Research
, vol.61
, Issue.20
, pp. 7435-7443
-
-
Weeks, B.H.1
-
76
-
-
22144490495
-
Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis
-
15937546 1:CAS:528:DC%2BD2MXlvF2qtr4%3D
-
Han, G.; et al. (2005). Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. The Journal of Clinical Investigation, 115(7), 1714-1723.
-
(2005)
The Journal of Clinical Investigation
, vol.115
, Issue.7
, pp. 1714-1723
-
-
Han, G.1
-
77
-
-
77956893106
-
TGF-beta inhibits metastasis in late stage human squamous cell carcinoma of the skin by a mechanism that does not involve Id1
-
Ganapathy, A.; et al. (2010). TGF-beta inhibits metastasis in late stage human squamous cell carcinoma of the skin by a mechanism that does not involve Id1. Cancer Letters, 298(1), 107-118.
-
(2010)
Cancer Letters
, vol.298
, Issue.1
, pp. 107-118
-
-
Ganapathy, A.1
-
78
-
-
0035199487
-
Invasion and metastasis of a mammary tumor involves TGF-beta signaling
-
1:CAS:528:DC%2BD3cXovF2htLk%3D
-
McEarchern, J. A.; et al. (2001). Invasion and metastasis of a mammary tumor involves TGF-beta signaling. International Journal of Cancer, 91(1), 76-82.
-
(2001)
International Journal of Cancer
, vol.91
, Issue.1
, pp. 76-82
-
-
McEarchern, J.A.1
-
79
-
-
0037816160
-
Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
-
12808151 1:CAS:528:DC%2BD3sXlsFGntLc%3D
-
Siegel, P. M.; et al. (2003). Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis. Proceedings of the National Academy of Sciences of the United States of America, 100(14), 8430-8435.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8430-8435
-
-
Siegel, P.M.1
-
80
-
-
51049111434
-
Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: Implications for proliferation and migration in vitro and metastasis in vivo
-
18676771 1:CAS:528:DC%2BD1cXpt1eis7s%3D
-
Moore, L. D.; et al. (2008). Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo. Clinical Cancer Research, 14(15), 4961-4970.
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.15
, pp. 4961-4970
-
-
Moore, L.D.1
-
81
-
-
0033215194
-
A soluble transforming growth factor beta type III receptor suppresses tumorigenicity and metastasis of human breast cancer MDA-MB-231 cells
-
10519421 1:CAS:528:DyaK1MXmslWkurs%3D
-
Bandyopadhyay, A.; et al. (1999). A soluble transforming growth factor beta type III receptor suppresses tumorigenicity and metastasis of human breast cancer MDA-MB-231 cells. Cancer Research, 59(19), 5041-5046.
-
(1999)
Cancer Research
, vol.59
, Issue.19
, pp. 5041-5046
-
-
Bandyopadhyay, A.1
-
82
-
-
3042738106
-
Smad-binding defective mutant of transforming growth factor beta type i receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
-
15231662 1:CAS:528:DC%2BD2cXltlOrsLk%3D
-
Tian, F.; et al. (2004). Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Research, 64(13), 4523-4530.
-
(2004)
Cancer Research
, vol.64
, Issue.13
, pp. 4523-4530
-
-
Tian, F.1
-
83
-
-
16844373628
-
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis
-
15781643 1:CAS:528:DC%2BD2MXisFGnsro%3D
-
Forrester, E.; et al. (2005). Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Cancer Research, 65(6), 2296-2302.
-
(2005)
Cancer Research
, vol.65
, Issue.6
, pp. 2296-2302
-
-
Forrester, E.1
-
84
-
-
37349100945
-
+ myeloid cells that promote metastasis
-
18167337 1:CAS:528:DC%2BD1cXnsVKnuw%3D%3D
-
+ myeloid cells that promote metastasis. Cancer Cell, 13(1), 23-35.
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 23-35
-
-
Yang, L.1
-
85
-
-
0033032231
-
Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice
-
10100726 1:CAS:528:DyaK1MXitVyitrw%3D
-
Stearns, M. E.; et al. (1999). Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice. Clinical Cancer Research, 5(3), 711-720.
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.3
, pp. 711-720
-
-
Stearns, M.E.1
-
86
-
-
10744222982
-
The loss of TGF-beta signaling promotes prostate cancer metastasis
-
12869309 1:CAS:528:DC%2BD3sXlvF2ltrY%3D
-
Tu, W. H.; et al. (2003). The loss of TGF-beta signaling promotes prostate cancer metastasis. Neoplasia, 5(3), 267-277.
-
(2003)
Neoplasia
, vol.5
, Issue.3
, pp. 267-277
-
-
Tu, W.H.1
-
87
-
-
0015008620
-
Isolation of a tumor factor responsible for angiogenesis
-
4332371 1:STN:280:DyaE38%2Fot1SgsA%3D%3D
-
Folkman, J.; et al. (1971). Isolation of a tumor factor responsible for angiogenesis. The Journal of Experimental Medicine, 133(2), 275-288.
-
(1971)
The Journal of Experimental Medicine
, vol.133
, Issue.2
, pp. 275-288
-
-
Folkman, J.1
-
88
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
6823562 1:STN:280:DyaL3s7hvF2mtw%3D%3D
-
Senger, D. R.; et al. (1983). Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science, 219(4587), 983-985.
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 983-985
-
-
Senger, D.R.1
-
89
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
2479986 1:CAS:528:DyaK3cXls1GltLo%3D
-
Leung, D. W.; et al. (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 246(4935), 1306-1309.
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1306-1309
-
-
Leung, D.W.1
-
90
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
7683111 1:CAS:528:DyaK3sXktVKju7s%3D
-
Kim, K. J.; et al. (1993). Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature, 362(6423), 841-844.
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
-
91
-
-
0030059075
-
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
-
8631034 1:CAS:528:DyaK28XhtVCltrc%3D
-
Melnyk, O.; Shuman, M. A.; & Kim, K. J. (1996). Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth. Cancer Research, 56(4), 921-924.
-
(1996)
Cancer Research
, vol.56
, Issue.4
, pp. 921-924
-
-
Melnyk, O.1
Shuman, M.A.2
Kim, K.J.3
-
92
-
-
13144262858
-
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
-
9671758 1:CAS:528:DyaK1cXkvFalsbY%3D
-
Goldman, C. K.; et al. (1998). Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proceedings of the National Academy of Sciences of the United States of America, 95(15), 8795-8800.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.15
, pp. 8795-8800
-
-
Goldman, C.K.1
-
93
-
-
17044441694
-
Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers
-
12086892 1:CAS:528:DC%2BD38XitlCmsbY%3D
-
Eriksson, A.; et al. (2002). Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers. Cancer Cell, 1(1), 99-108.
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 99-108
-
-
Eriksson, A.1
-
94
-
-
0036023438
-
Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production
-
12171905 1:CAS:528:DC%2BD38XmvVaht7o%3D
-
Sweeney, P.; et al. (2002). Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production. Clinical Cancer Research, 8(8), 2714-2724.
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.8
, pp. 2714-2724
-
-
Sweeney, P.1
-
95
-
-
70349439129
-
Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells
-
19597469 1:CAS:528:DC%2BD1MXosFWhsbk%3D
-
Dai, J.; et al. (2009). Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells. Oncogene, 28(38), 3412-3422.
-
(2009)
Oncogene
, vol.28
, Issue.38
, pp. 3412-3422
-
-
Dai, J.1
-
96
-
-
0035137171
-
Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: Implications for human breast cancer
-
11238891 1:CAS:528:DC%2BD3MXhtlGhs70%3D
-
Dankort, D.; et al. (2001). Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: Implications for human breast cancer. Molecular and Cellular Biology, 21(5), 1540-1551.
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.5
, pp. 1540-1551
-
-
Dankort, D.1
-
97
-
-
1642453824
-
Angiogenic acceleration of Neu induced mammary tumor progression and metastasis
-
14729621 1:CAS:528:DC%2BD2cXkslymtw%3D%3D
-
Oshima, R. G.; et al. (2004). Angiogenic acceleration of Neu induced mammary tumor progression and metastasis. Cancer Research, 64(1), 169-179.
-
(2004)
Cancer Research
, vol.64
, Issue.1
, pp. 169-179
-
-
Oshima, R.G.1
-
98
-
-
1842836011
-
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells
-
12748308 1:CAS:528:DC%2BD3sXkvVersb8%3D
-
Laird, A. D.; et al. (2003). Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells. Molecular Cancer Therapeutics, 2(5), 461-469.
-
(2003)
Molecular Cancer Therapeutics
, vol.2
, Issue.5
, pp. 461-469
-
-
Laird, A.D.1
-
99
-
-
34248397608
-
Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells
-
12509223
-
Chou, M. T.; Wang, J.; & Fujita, D. J. (2002). Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells. BMC Biochemistry, 3, 32.
-
(2002)
BMC Biochemistry
, vol.3
, pp. 32
-
-
Chou, M.T.1
Wang, J.2
Fujita, D.J.3
-
100
-
-
0033393771
-
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
-
10635317 1:CAS:528:DC%2BD3cXislarsw%3D%3D
-
Eliceiri, B. P.; et al. (1999). Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Molecular Cell, 4(6), 915-924.
-
(1999)
Molecular Cell
, vol.4
, Issue.6
, pp. 915-924
-
-
Eliceiri, B.P.1
-
101
-
-
7244247062
-
Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis
-
15504909 1:CAS:528:DC%2BD2cXptVKqt7c%3D
-
Weis, S.; et al. (2004). Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. The Journal of Cell Biology, 167(2), 223-229.
-
(2004)
The Journal of Cell Biology
, vol.167
, Issue.2
, pp. 223-229
-
-
Weis, S.1
-
102
-
-
81155126054
-
Chemotherapy enhances metastasis formation via VEGFR-1-expressing endothelial cells
-
Daenen, L. G.; et al. (2011). Chemotherapy enhances metastasis formation via VEGFR-1-expressing endothelial cells. Cancer Research, 71(22), 6976-6985.
-
(2011)
Cancer Research
, vol.71
, Issue.22
, pp. 6976-6985
-
-
Daenen, L.G.1
-
103
-
-
65449159747
-
A compact VEGF signature associated with distant metastases and poor outcomes
-
19291283
-
Hu, Z.; et al. (2009). A compact VEGF signature associated with distant metastases and poor outcomes. BMC Medicine, 7, 9.
-
(2009)
BMC Medicine
, vol.7
, pp. 9
-
-
Hu, Z.1
-
104
-
-
0037461934
-
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
-
12545153 1:CAS:528:DC%2BD3sXlsV2ltA%3D%3D
-
Wei, D.; et al. (2003). Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene, 22(3), 319-329.
-
(2003)
Oncogene
, vol.22
, Issue.3
, pp. 319-329
-
-
Wei, D.1
-
105
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
16007214 1:CAS:528:DC%2BD2MXovVOns7c%3D
-
Xu, Q.; et al. (2005). Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene, 24(36), 5552-5560.
-
(2005)
Oncogene
, vol.24
, Issue.36
, pp. 5552-5560
-
-
Xu, Q.1
-
106
-
-
34547093162
-
Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model
-
17634549 1:CAS:528:DC%2BD2sXnvVChsLs%3D
-
Verheul, H. M.; et al. (2007). Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model. Clinical Cancer Research, 13(14), 4201-4208.
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.14
, pp. 4201-4208
-
-
Verheul, H.M.1
-
107
-
-
0033763198
-
Expression of vascular endothelial growth factor by human renal cancer cells enhances angiogenesis of primary tumors and production of ascites but not metastasis to the lungs in nude mice
-
1:CAS:528:DC%2BD3cXos1Oku7Y%3D
-
Kanayama, H.; et al. (1999). Expression of vascular endothelial growth factor by human renal cancer cells enhances angiogenesis of primary tumors and production of ascites but not metastasis to the lungs in nude mice. Clinical & Experimental Metastasis, 17(10), 831-840.
-
(1999)
Clinical & Experimental Metastasis
, vol.17
, Issue.10
, pp. 831-840
-
-
Kanayama, H.1
-
108
-
-
0034283023
-
Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
-
10987309 1:CAS:528:DC%2BD3cXmsFWhsb0%3D
-
Rofstad, E. K.; & Halsor, E. F. (2000). Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts. Cancer Research, 60(17), 4932-4938.
-
(2000)
Cancer Research
, vol.60
, Issue.17
, pp. 4932-4938
-
-
Rofstad, E.K.1
Halsor, E.F.2
-
109
-
-
73849129203
-
Real-time imaging reveals the single steps of brain metastasis formation
-
Kienast, Y.; et al. (2009). Real-time imaging reveals the single steps of brain metastasis formation. Nature Medicine, 16(1), 116-122.
-
(2009)
Nature Medicine
, vol.16
, Issue.1
, pp. 116-122
-
-
Kienast, Y.1
-
110
-
-
0141725532
-
Novel therapeutic strategies targeting the epidermal growth factor receptor (EGFR) family and its downstream effectors in breast cancer
-
12954573 1:STN:280:DC%2BD3svhsV2qtQ%3D%3D
-
Atalay, G.; et al. (2003). Novel therapeutic strategies targeting the epidermal growth factor receptor (EGFR) family and its downstream effectors in breast cancer. Annals of Oncology, 14(9), 1346-1363.
-
(2003)
Annals of Oncology
, vol.14
, Issue.9
, pp. 1346-1363
-
-
Atalay, G.1
-
111
-
-
80052591747
-
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab
-
Yonesaka, K.; et al. (2011). Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Science Translational Medicine, 3(99), 99ra86.
-
(2011)
Science Translational Medicine
, vol.3
, Issue.99
-
-
Yonesaka, K.1
-
112
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo, M.; et al. (2010). Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. New England Journal of Medicine, 362(25), 2380-2388.
-
(2010)
New England Journal of Medicine
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
-
113
-
-
84857088600
-
Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer metastatic to the brain
-
Jamal-Hanjani, M.; & Spicer, J. (2011). Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer metastatic to the brain. Clinical Cancer Research, 18(4), 938-944.
-
(2011)
Clinical Cancer Research
, vol.18
, Issue.4
, pp. 938-944
-
-
Jamal-Hanjani, M.1
Spicer, J.2
-
114
-
-
77949754385
-
Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer
-
Cristofanilli, M.; et al. (2010). Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer. Clinical Cancer Research, 16(6), 1904-1914.
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.6
, pp. 1904-1914
-
-
Cristofanilli, M.1
-
115
-
-
57149089886
-
EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
-
18794545 1:CAS:528:DC%2BD1MXmsVSkug%3D%3D
-
Takano, T.; et al. (2008). EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan. Journal of Clinical Oncology, 26(34), 5589-5595.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.34
, pp. 5589-5595
-
-
Takano, T.1
-
116
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
Sequist, L. V.; et al. (2011). Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Science Translational Medicine, 3(75), 75ra26.
-
(2011)
Science Translational Medicine
, vol.3
, Issue.75
-
-
Sequist, L.V.1
-
117
-
-
84655162706
-
Treatment of HER2-positive breast cancer: Current status and future perspectives
-
Arteaga, C. L.; et al. (2011). Treatment of HER2-positive breast cancer: current status and future perspectives. Nature Reviews Clinical Oncology, 9(1), 16-32.
-
(2011)
Nature Reviews Clinical Oncology
, vol.9
, Issue.1
, pp. 16-32
-
-
Arteaga, C.L.1
-
118
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
11821453 1:CAS:528:DC%2BD38XhsVGmt7o%3D
-
Vogel, C. L.; et al. (2002). Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. Journal of Clinical Oncology, 20(3), 719-726.
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.3
, pp. 719-726
-
-
Vogel, C.L.1
-
119
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
16236737 1:CAS:528:DC%2BD2MXhtFansr3L
-
Piccart-Gebhart, M. J.; et al. (2005). Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. The New England Journal of Medicine, 353(16), 1659-1672.
-
(2005)
The New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
-
120
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
16236738 1:CAS:528:DC%2BD2MXhtFansr3F
-
Romond, E. H.; et al. (2005). Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. The New England Journal of Medicine, 353(16), 1673-1684.
-
(2005)
The New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
-
121
-
-
62549135630
-
Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients
-
19240719 1:CAS:528:DC%2BD1MXjt1Gjsb8%3D
-
Park, Y. H.; et al. (2009). Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients. British Journal of Cancer, 100(6), 894-900.
-
(2009)
British Journal of Cancer
, vol.100
, Issue.6
, pp. 894-900
-
-
Park, Y.H.1
-
122
-
-
79953745096
-
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
-
Zhang, S.; et al. (2011). Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nature Medicine, 17(4), 461-469.
-
(2011)
Nature Medicine
, vol.17
, Issue.4
, pp. 461-469
-
-
Zhang, S.1
-
123
-
-
77953200582
-
Trastuzumab emtansine, an antibody-drug conjugate for the treatment of HER2+ metastatic breast cancer
-
Niculescu-Duvaz, I. (2010). Trastuzumab emtansine, an antibody-drug conjugate for the treatment of HER2+ metastatic breast cancer. Curr Opin Mol Ther, 12(3), 350-360.
-
(2010)
Curr Opin Mol Ther
, vol.12
, Issue.3
, pp. 350-360
-
-
Niculescu-Duvaz, I.1
-
124
-
-
83255186301
-
Multi-targeted tyrosine kinase inhibitors in clinical development: Focus on XL-184 (cabozantinib)
-
Barcelona, Spain
-
Bowles, D. W.; Kessler, E. R.; & Jimeno, A. (2011). Multi-targeted tyrosine kinase inhibitors in clinical development: focus on XL-184 (cabozantinib). Drugs Today (Barcelona, Spain), 47(11), 857-868.
-
(2011)
Drugs Today
, vol.47
, Issue.11
, pp. 857-868
-
-
Bowles D., .W.1
Kessler E., .R.2
Jimeno, A.3
-
125
-
-
84879783728
-
ARQ 197 Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous
-
Accessed on 1 Mar 2012
-
ArQule, D. S. D. L. (2012). ARQ 197 Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung Cancer. http://clinicaltrials.gov/ct2/show/NCT01244191. Accessed on 1 Mar 2012.
-
(2012)
Non-small-cell Lung Cancer
-
-
Arqule, D.S.D.L.1
-
127
-
-
32944467848
-
Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors
-
16452232 1:CAS:528:DC%2BD28XpsVelsg%3D%3D
-
Burgess, T.; et al. (2006). Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors. Cancer Research, 66(3), 1721-1729.
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1721-1729
-
-
Burgess, T.1
-
128
-
-
4143136640
-
Vascular endothelial growth factor: Basic science and clinical progress
-
15294883 1:CAS:528:DC%2BD2cXns1Ght74%3D
-
Ferrara, N. (2004). Vascular endothelial growth factor: Basic science and clinical progress. Endocrine Reviews, 25(4), 581-611.
-
(2004)
Endocrine Reviews
, vol.25
, Issue.4
, pp. 581-611
-
-
Ferrara, N.1
-
129
-
-
84868001100
-
Roche still sees peak Avastin sales 7 billion francs
-
Roche still sees peak Avastin sales 7 billion francs. Reuters, 2011.
-
(2011)
Reuters
-
-
-
131
-
-
84855425106
-
Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
Burger, R. A.; et al. (2011). Incorporation of bevacizumab in the primary treatment of ovarian cancer. New England Journal of Medicine, 365(26), 2473-2483.
-
(2011)
New England Journal of Medicine
, vol.365
, Issue.26
, pp. 2473-2483
-
-
Burger, R.A.1
-
132
-
-
77951473661
-
Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: Results from a randomised phase III trial (AVAiL)
-
Reck, M.; et al. (2010). Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Annals of Oncology, 21(9), 1804-1809.
-
(2010)
Annals of Oncology
, vol.21
, Issue.9
, pp. 1804-1809
-
-
Reck, M.1
-
133
-
-
84876288831
-
A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as frontline therapy for metastatic colorectal cancer. A Fox Chase extramural research study
-
doi: 10.1007/s12029-012-9368-3
-
Dotan, E.; et al. (2012). A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as frontline therapy for metastatic colorectal cancer. A Fox Chase extramural research study. Journal of Gastrointestinal Cancer. doi: 10.1007/s12029-012-9368-3.
-
(2012)
Journal of Gastrointestinal Cancer
-
-
Dotan, E.1
-
134
-
-
75349102521
-
Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: A systematic review and economic evaluation
-
iii-iv
-
Thompson Coon, J.; et al. (2010). Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: A systematic review and economic evaluation. Health Technology Assessessment, 14(2), 1-184, iii-iv.
-
(2010)
Health Technology Assessessment
, vol.14
, Issue.2
, pp. 1-184
-
-
Thompson Coon, J.1
-
135
-
-
84860248128
-
Pazopanib: An orally administered multi-targeted tyrosine kinase inhibitor for locally advanced or metastatic renal cell carcinoma
-
Koc, G.; Wang, X.; & Luo, Y. (2011). Pazopanib: an orally administered multi-targeted tyrosine kinase inhibitor for locally advanced or metastatic renal cell carcinoma. The Canadian Journal of Urology, 18(6), 5991-5997.
-
(2011)
The Canadian Journal of Urology
, vol.18
, Issue.6
, pp. 5991-5997
-
-
Koc, G.1
Wang, X.2
Luo, Y.3
-
136
-
-
84855379256
-
Market watch: Upcoming market catalysts in Q1 2012
-
Inui, E. (2012). Market watch: upcoming market catalysts in Q1 2012. Nature Reviews Drug Discovery, 11(1), 10.
-
(2012)
Nature Reviews Drug Discovery
, vol.11
, Issue.1
, pp. 10
-
-
Inui, E.1
-
137
-
-
84857407549
-
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
-
Conley, S. J.; et al. (2012). Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia. Proceedings of the National Academy of Sciences of the United States of America, 109(8), 2784-2789.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.8
, pp. 2784-2789
-
-
Conley, S.J.1
-
138
-
-
80054793877
-
Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis
-
Park, E. S.; et al. (2011). Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis. Proceedings of the National Academy of Sciences of the United States of America, 108(42), 17456-17461.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.42
, pp. 17456-17461
-
-
Park, E.S.1
-
139
-
-
78650305549
-
The bone remodeling environment is a factor in breast cancer bone metastasis
-
Ooi, L. L.; et al. (2011). The bone remodeling environment is a factor in breast cancer bone metastasis. Bone, 48(1), 66-70.
-
(2011)
Bone
, vol.48
, Issue.1
, pp. 66-70
-
-
Ooi, L.L.1
-
140
-
-
53849106456
-
Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption
-
1:CAS:528:DC%2BD1cXht1Knt73J
-
Sims, N. A.; & Gooi, J. H. (2008). Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption. Seminars in Cell & Developmental Biology, 19(5), 444-451.
-
(2008)
Seminars in Cell & Developmental Biology
, vol.19
, Issue.5
, pp. 444-451
-
-
Sims, N.A.1
Gooi, J.H.2
-
141
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi, N.; et al. (2011). Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell, 19(2), 192-205.
-
(2011)
Cancer Cell
, vol.19
, Issue.2
, pp. 192-205
-
-
Sethi, N.1
-
143
-
-
77953455677
-
Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model
-
Yang, J. C.; et al. (2010). Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model. Molecular Cancer Therapeutics, 9(6), 1629-1637.
-
(2010)
Molecular Cancer Therapeutics
, vol.9
, Issue.6
, pp. 1629-1637
-
-
Yang, J.C.1
-
145
-
-
0035966319
-
MicroRNAs: Tiny regulators with great potential
-
11779458 1:CAS:528:DC%2BD38XjtlKmtg%3D%3D
-
Ambros, V. (2001). microRNAs: Tiny regulators with great potential. Cell, 107(7), 823-826.
-
(2001)
Cell
, vol.107
, Issue.7
, pp. 823-826
-
-
Ambros, V.1
-
146
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
14744438 1:CAS:528:DC%2BD2cXhtVals7o%3D
-
Bartel, D. P. (2004). MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell, 116(2), 281-297.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
147
-
-
84862872964
-
MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer
-
doi: 10.1002/pros.22466
-
Xu, B.; et al. (2012). MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. Prostate. doi: 10.1002/pros.22466.
-
(2012)
Prostate
-
-
Xu, B.1
-
148
-
-
79956313718
-
Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
-
Gong, C.; et al. (2011). Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. The Journal of Biological Chemistry, 286(21), 19127-19137.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.21
, pp. 19127-19137
-
-
Gong, C.1
-
149
-
-
80054047147
-
MiR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer
-
Tsuruta, T.; et al. (2011). miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. Cancer Research, 71(20), 6450-6462.
-
(2011)
Cancer Research
, vol.71
, Issue.20
, pp. 6450-6462
-
-
Tsuruta, T.1
-
150
-
-
84856369168
-
MIR-99a and MIR-99b modulate TGF-beta induced epithelial to mesenchymal plasticity in normal murine mammary gland cells
-
Turcatel, G.; et al. (2012). MIR-99a and MIR-99b modulate TGF-beta induced epithelial to mesenchymal plasticity in normal murine mammary gland cells. PLoS One, 7(1), e31032.
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Turcatel, G.1
-
151
-
-
84863031502
-
MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A
-
Yue, X.; et al. (2011). MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A. Oncology Reports, 27(4), 1200-1206.
-
(2011)
Oncology Reports
, vol.27
, Issue.4
, pp. 1200-1206
-
-
Yue, X.1
-
153
-
-
84855543629
-
EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers
-
Garofalo, M.; et al. (2011). EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nature Medicine, 18(1), 74-82.
-
(2011)
Nature Medicine
, vol.18
, Issue.1
, pp. 74-82
-
-
Garofalo, M.1
|