Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis

Oncogene

Volumn 18, Issue 5, 1999, Pages 1139-1146

  Bardelli, Alberto ^a   Basile, Maria Lisa ^a   Audero, Enrica ^a   Giordano, Silvia ^a   Wennström, Stefan ^b   Ménard, Sylvie ^c   Comoglio, Paolo M ^a   Ponzetto, Carola ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Grb2; Met signaling; Met mediated metastasis; PI 3 kinase; Ras

Indexed keywords

PROTEIN TYROSINE KINASE; RAS PROTEIN; SCATTER FACTOR;

ARTICLE; METASTASIS; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CONSENSUS SEQUENCE; COS CELLS; DOGS; ENZYME ACTIVATION; FIBROBLASTS; GRB2 ADAPTOR PROTEIN; MICE; MICE, NUDE; MUTATION; NEOPLASM METASTASIS; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MET; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 0033521924     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202607     Document Type: Article

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