메뉴 건너뛰기




Volumn 21, Issue 12, 2001, Pages 4016-4031

Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBRONECTIN; FOCAL ADHESION KINASE; PAXILLIN; PROTEIN TYROSINE KINASE INHIBITOR; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0035018353     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.12.4016-4031.2001     Document Type: Article
Times cited : (294)

References (81)
  • 1
    • 0345593816 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts
    • Angers-Loustau, A., J. F. Cote, A. Charest, D. Dowbenko, S. Spencer, L. A. Lasky, and M. L. Tremblay. 1999. Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J. Cell. Biol. 144:1019-1031.
    • (1999) J. Cell. Biol. , vol.144 , pp. 1019-1031
    • Angers-Loustau, A.1    Cote, J.F.2    Charest, A.3    Dowbenko, D.4    Spencer, S.5    Lasky, L.A.6    Tremblay, M.L.7
  • 2
    • 0034024403 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
    • Arcaro, A., M. J. Zvelebil, C. Wallasch, A. Ullrich, M. D. Waterfield, and J. Domin. 2000. Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. Mol. Cell. Biol. 20:3817-3830.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3817-3830
    • Arcaro, A.1    Zvelebil, M.J.2    Wallasch, C.3    Ullrich, A.4    Waterfield, M.D.5    Domin, J.6
  • 3
    • 0020039865 scopus 로고
    • Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture
    • Barnes, D. W. 1982. Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. J. Cell. Biol. 93:1-4.
    • (1982) J. Cell. Biol. , vol.93 , pp. 1-4
    • Barnes, D.W.1
  • 5
    • 0027759435 scopus 로고
    • Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells
    • Birchmeier, W., K. M. Weidner, and J. Behrens. 1993. Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells. J. Cell Sci. Suppl. 17:159-164.
    • (1993) J. Cell Sci. Suppl. , vol.17 , pp. 159-164
    • Birchmeier, W.1    Weidner, K.M.2    Behrens, J.3
  • 6
    • 0026445719 scopus 로고
    • Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
    • Burridge, K., C. E. Turner, and L. H. Romer. 1992. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J. Cell. Biol. 119:893-903.
    • (1992) J. Cell. Biol. , vol.119 , pp. 893-903
    • Burridge, K.1    Turner, C.E.2    Romer, L.H.3
  • 7
    • 0028877919 scopus 로고
    • Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases
    • Calalb, M. B., T. R. Polte, and S. K. Hanks. 1995. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol. Cell. Biol. 15:954-963.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 954-963
    • Calalb, M.B.1    Polte, T.R.2    Hanks, S.K.3
  • 8
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary, L. A., J. F. Chang, and J. L. Guan. 1996. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J. Cell Sci. 109:1787-1794.
    • (1996) J. Cell Sci. , vol.109 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.L.3
  • 9
    • 0032509565 scopus 로고    scopus 로고
    • Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration
    • Cary, L. A., D. C. Han, T. R. Polte, S. K. Hanks, and J. L. Guan. 1998. Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. J. Cell. Biol. 140:211-221.
    • (1998) J. Cell. Biol. , vol.140 , pp. 211-221
    • Cary, L.A.1    Han, D.C.2    Polte, T.R.3    Hanks, S.K.4    Guan, J.L.5
  • 10
    • 0029979722 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
    • Chen, H. C., P. A. Appeddu, H. Isoda, and J. L. Guan. 1996. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J. Biol. Chem. 271:26329-26334.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26329-26334
    • Chen, H.C.1    Appeddu, P.A.2    Isoda, H.3    Guan, J.L.4
  • 12
    • 0019497676 scopus 로고
    • Rapid rounding of human epidermoid carcinoma cells A-431 induced by epidermal growth factor
    • Chinkers, M., J. A. McKanna, and S. Cohen. 1981. Rapid rounding of human epidermoid carcinoma cells A-431 induced by epidermal growth factor. J. Cell. Biol. 88:422-429.
    • (1981) J. Cell. Biol. , vol.88 , pp. 422-429
    • Chinkers, M.1    McKanna, J.A.2    Cohen, S.3
  • 13
    • 0031797018 scopus 로고    scopus 로고
    • Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement
    • Danjo, Y., and I. K. Gipson. 1998. Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement. J. Cell Sci. 111:3323-3332.
    • (1998) J. Cell Sci. , vol.111 , pp. 3323-3332
    • Danjo, Y.1    Gipson, I.K.2
  • 14
    • 0029935297 scopus 로고    scopus 로고
    • Growth factor-independent proliferation of rat mammary carcinoma cells by autocrine secretion of neu-differentiation factor/heregulin and transforming growth factor-alpha
    • Ethier, S. P., B. C. Langton, and C. A. Dilts. 1996. Growth factor-independent proliferation of rat mammary carcinoma cells by autocrine secretion of neu-differentiation factor/heregulin and transforming growth factor-alpha. Mol. Carcinog. 15:134-143.
    • (1996) Mol. Carcinog. , vol.15 , pp. 134-143
    • Ethier, S.P.1    Langton, B.C.2    Dilts, C.A.3
  • 15
    • 0032400495 scopus 로고    scopus 로고
    • Cell migration strategies in 3-D extracellular matrix: Differences in morphology, cell matrix interactions, and integrin function
    • Friedl, P., K. S. Zanker, and E. B. Brocker. 1998. Cell migration strategies in 3-D extracellular matrix: differences in morphology, cell matrix interactions, and integrin function. Microsc. Res. Technol. 43:369-378.
    • (1998) Microsc. Res. Technol. , vol.43 , pp. 369-378
    • Friedl, P.1    Zanker, K.S.2    Brocker, E.B.3
  • 16
    • 0033524928 scopus 로고    scopus 로고
    • Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST
    • Garton, A. J., and N. K. Tonks. 1999. Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. J. Biol. Chem. 274:3811-3818.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3811-3818
    • Garton, A.J.1    Tonks, N.K.2
  • 17
    • 0022217557 scopus 로고
    • Epidermal growth factor stimulates the growth of A431 tumors in athymic mice
    • Ginsburg, E., and B. K. Vonderhaar. 1985. Epidermal growth factor stimulates the growth of A431 tumors in athymic mice. Cancer Lett. 28:143-150.
    • (1985) Cancer Lett. , vol.28 , pp. 143-150
    • Ginsburg, E.1    Vonderhaar, B.K.2
  • 18
    • 0026759309 scopus 로고
    • Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
    • Guan, J. L., and D. Shalloway. 1992. Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation. Nature 358:690-692.
    • (1992) Nature , vol.358 , pp. 690-692
    • Guan, J.L.1    Shalloway, D.2
  • 19
    • 0028951464 scopus 로고
    • Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase
    • Guinebault, C., B. Payrastre, C. Racaud-Sultan, H. Mazarguil, M. Breton, G. Mauco, M. Plantavid, and H. Chap. 1995. Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase. J. Cell. Biol. 129:831-842.
    • (1995) J. Cell. Biol. , vol.129 , pp. 831-842
    • Guinebault, C.1    Payrastre, B.2    Racaud-Sultan, C.3    Mazarguil, H.4    Breton, M.5    Mauco, G.6    Plantavid, M.7    Chap, H.8
  • 20
    • 0026028343 scopus 로고
    • Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers
    • Gullick, W. J. 1991. Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br. Med. Bull. 47:87-98.
    • (1991) Br. Med. Bull. , vol.47 , pp. 87-98
    • Gullick, W.J.1
  • 21
    • 0033603879 scopus 로고    scopus 로고
    • The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK. Cas, and paxillin
    • Guvakova, M. A., and E. Surmacz. 1999. The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK. Cas, and paxillin. Exp. Cell Res. 251:244-255.
    • (1999) Exp. Cell Res. , vol.251 , pp. 244-255
    • Guvakova, M.A.1    Surmacz, E.2
  • 22
    • 0029666251 scopus 로고    scopus 로고
    • p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase
    • Harte, M. T., J. D. Hildebrand, M. R. Burnham, A. H. Bouton, and J. T. Parsons. 1996. p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J. Biol. Chem. 271:13649-13655.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13649-13655
    • Harte, M.T.1    Hildebrand, J.D.2    Burnham, M.R.3    Bouton, A.H.4    Parsons, J.T.5
  • 23
    • 0032819098 scopus 로고    scopus 로고
    • Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins
    • Hassid, A., S. Huang, and J. Yao. 1999. Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins. Am. J. Physiol. 277:H192-H198.
    • (1999) Am. J. Physiol. , vol.277
    • Hassid, A.1    Huang, S.2    Yao, J.3
  • 24
    • 0034731351 scopus 로고    scopus 로고
    • Focal adhesion kinase facilitates platelet-derived growth factor-BB-stimulated ERK2 activation required for chemotaxis migration of vascular smooth muscle cells
    • Hauck, C. R., D. A. Hsia, and D. D. Schlaepfer. 2000. Focal adhesion kinase facilitates platelet-derived growth factor-BB-stimulated ERK2 activation required for chemotaxis migration of vascular smooth muscle cells. J. Biol. Chem. 275:41092-41099.
    • (2000) J. Biol. Chem. , vol.275 , pp. 41092-41099
    • Hauck, C.R.1    Hsia, D.A.2    Schlaepfer, D.D.3
  • 25
    • 0029055784 scopus 로고
    • Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase
    • Hildebrand, J. D., M. D. Schaller, and J. T. Parsons. 1995. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol. Biol. Cell 6:637-647.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 637-647
    • Hildebrand, J.D.1    Schaller, M.D.2    Parsons, J.T.3
  • 26
    • 0029955660 scopus 로고    scopus 로고
    • An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
    • Hildebrand, J. D., J. M. Taylor, and J. T. Parsons. 1996. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol. Cell. Biol. 16:3169-3178.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3169-3178
    • Hildebrand, J.D.1    Taylor, J.M.2    Parsons, J.T.3
  • 29
    • 0033623796 scopus 로고    scopus 로고
    • pp60(cSrc) is a caspase-3 substrate and is essential for the transformed phenotype of A431 cells
    • Karni, R., and A. Levitzki. 2000. pp60(cSrc) is a caspase-3 substrate and is essential for the transformed phenotype of A431 cells. Mol. Cell. Biol. Res. Commun. 3:98-104.
    • (2000) Mol. Cell. Biol. Res. Commun. , vol.3 , pp. 98-104
    • Karni, R.1    Levitzki, A.2
  • 30
    • 0010233988 scopus 로고
    • Growth stimulation of A431 cells by epidermal growth factor: Identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
    • Kawamoto, T., J. D. Sato, A. Le, J. Polikoff, G. H. Sato, and J. Mendelsohn. 1983. Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc. Natl. Acad. Sci. USA 80:1337-1341.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 1337-1341
    • Kawamoto, T.1    Sato, J.D.2    Le, A.3    Polikoff, J.4    Sato, G.H.5    Mendelsohn, J.6
  • 31
    • 0032833791 scopus 로고    scopus 로고
    • EGF receptor signaling in prostate morphogenesis and tumorigenesis
    • Kim, H. G., J. Kassis, J. C. Souto, T. Turner, and A. Wells. 1999. EGF receptor signaling in prostate morphogenesis and tumorigenesis. Histol. Histopathol. 14:1175-1182.
    • (1999) Histol. Histopathol. , vol.14 , pp. 1175-1182
    • Kim, H.G.1    Kassis, J.2    Souto, J.C.3    Turner, T.4    Wells, A.5
  • 32
    • 0032493871 scopus 로고    scopus 로고
    • Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
    • Kim, J., W. Yu, K. Kovalski, and L. Ossowski. 1998. Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell 94:353-362.
    • (1998) Cell , vol.94 , pp. 353-362
    • Kim, J.1    Yu, W.2    Kovalski, K.3    Ossowski, L.4
  • 34
    • 0032559562 scopus 로고    scopus 로고
    • CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
    • Klemke, R. L., J. Leng, R. Molander, P. C. Brooks, K. Vuori, and D. A. Cheresh. 1998. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J. Cell. Biol. 140:961-972.
    • (1998) J. Cell. Biol. , vol.140 , pp. 961-972
    • Klemke, R.L.1    Leng, J.2    Molander, R.3    Brooks, P.C.4    Vuori, K.5    Cheresh, D.A.6
  • 35
    • 0023242425 scopus 로고
    • An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences: Application to hemophilia A
    • Kogan, S. C., M. Doherty, and J. Gitschier. 1987. An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences: application to hemophilia A. N. Engl. J. Med. 317:985-990.
    • (1987) N. Engl. J. Med. , vol.317 , pp. 985-990
    • Kogan, S.C.1    Doherty, M.2    Gitschier, J.3
  • 36
    • 0027055575 scopus 로고
    • Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
    • Kornberg, L., H. S. Earp, J. T. Parsons, M. Schaller, and R. L. Juliano. 1992. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J. Biol. Chem. 267:23439-23442.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23439-23442
    • Kornberg, L.1    Earp, H.S.2    Parsons, J.T.3    Schaller, M.4    Juliano, R.L.5
  • 37
    • 0025219657 scopus 로고
    • Growth regulation of A431 cells. Modulation of expression of transforming growth factor-alpha mRNA and 2′,5′-oligoadenylate synthetase activity
    • Kumar, R., and J. Mendelsohn. 1990. Growth regulation of A431 cells. Modulation of expression of transforming growth factor-alpha mRNA and 2′,5′-oligoadenylate synthetase activity. J. Biol. Chem. 265:4578-4582.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4578-4582
    • Kumar, R.1    Mendelsohn, J.2
  • 38
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: A physically integrated molecular process
    • Lauffenburger, D. A., and A. F. Horwitz. 1996. Cell migration: a physically integrated molecular process. Cell 84:359-369.
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 43
    • 0031848354 scopus 로고    scopus 로고
    • Role of epidermal-growth-factor receptor in tumor progression in transformed human mammary epithelial cells
    • Ma, L., C. Gauville, Y. Berthois, A. Degeorges, G. Millot, P. M. Martin, and F. Calvo. 1998. Role of epidermal-growth-factor receptor in tumor progression in transformed human mammary epithelial cells. Int. J. Cancer 78:112-119.
    • (1998) Int. J. Cancer , vol.78 , pp. 112-119
    • Ma, L.1    Gauville, C.2    Berthois, Y.3    Degeorges, A.4    Millot, G.5    Martin, P.M.6    Calvo, F.7
  • 44
    • 0027483931 scopus 로고
    • Activation of phosphotyrosine phosphatase activity by reduction of cell-substrate adhesion
    • Maher, P. A. 1993. Activation of phosphotyrosine phosphatase activity by reduction of cell-substrate adhesion. Proc. Natl. Acad. Sci. USA 90:11177-11181.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11177-11181
    • Maher, P.A.1
  • 45
    • 0039441744 scopus 로고    scopus 로고
    • Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility
    • Manes, S., E. Mira, C. Gomez-Mouton, Z. J. Zhao, R. A. Lacalle, and A. C. Martinez. 1999. Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility. Mol. Cell. Biol. 19:3125-3135.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3125-3135
    • Manes, S.1    Mira, E.2    Gomez-Mouton, C.3    Zhao, Z.J.4    Lacalle, R.A.5    Martinez, A.C.6
  • 47
    • 0033581873 scopus 로고    scopus 로고
    • Requirement for focal adhesion kinase in tumor cell adhesion
    • Maung, K., D. J. Easty, S. P. Hill, and D. C. Bennett. 1999. Requirement for focal adhesion kinase in tumor cell adhesion. Oncogene 18:6824-6828.
    • (1999) Oncogene , vol.18 , pp. 6824-6828
    • Maung, K.1    Easty, D.J.2    Hill, S.P.3    Bennett, D.C.4
  • 48
    • 0033785409 scopus 로고    scopus 로고
    • Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
    • Miao, H., E. Burnett, M. Kinch, E. Simon, and B. Wang. 2000. Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nat. Cell Biol. 2:62-69.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 62-69
    • Miao, H.1    Burnett, E.2    Kinch, M.3    Simon, E.4    Wang, B.5
  • 49
    • 0033053127 scopus 로고    scopus 로고
    • Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9
    • Mira, E., S. Manes, R. A. Lacalle, G. Marquez, and A. C. Martinez. 1999. Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9. Endocrinology 140:1657-1664.
    • (1999) Endocrinology , vol.140 , pp. 1657-1664
    • Mira, E.1    Manes, S.2    Lacalle, R.A.3    Marquez, G.4    Martinez, A.C.5
  • 50
    • 0030001058 scopus 로고    scopus 로고
    • The configuration of fibrin clots determines capillary morphogenesis and endothelial cell migration
    • Nehls, V., and R. Herrmann. 1996. The configuration of fibrin clots determines capillary morphogenesis and endothelial cell migration. Microvasc. Res. 51:347-364.
    • (1996) Microvasc. Res. , vol.51 , pp. 347-364
    • Nehls, V.1    Herrmann, R.2
  • 51
    • 0031570728 scopus 로고    scopus 로고
    • Cytoskeletal and morphological changes associated with the specific suppression of the epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid carcinoma
    • Nelson, J. M., and D. W. Fry. 1997. Cytoskeletal and morphological changes associated with the specific suppression of the epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid carcinoma. Exp. Cell Res. 233:383-390.
    • (1997) Exp. Cell Res. , vol.233 , pp. 383-390
    • Nelson, J.M.1    Fry, D.W.2
  • 52
    • 0032784060 scopus 로고    scopus 로고
    • Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase
    • Nolan, K., J. Lacoste, and J. T. Parsons. 1999. Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase. Mol. Cell. Biol. 19:6120-6129.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6120-6129
    • Nolan, K.1    Lacoste, J.2    Parsons, J.T.3
  • 53
    • 0033002997 scopus 로고    scopus 로고
    • Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto-and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2
    • Owen, J. D., P. J. Ruest, D. W. Fry, and S. K. Hanks. 1999. Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto-and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. Mol. Cell. Biol. 19:4806-4818.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4806-4818
    • Owen, J.D.1    Ruest, P.J.2    Fry, D.W.3    Hanks, S.K.4
  • 55
    • 0029907050 scopus 로고    scopus 로고
    • A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
    • Pasqualini, R., S. Bourdoulous, E. Koivunen, V. L. Woods, Jr., and E. Ruoslahti. 1996. A polymeric form of fibronectin has antimetastatic effects against multiple tumor types. Nat. Med. 2:1197-1203.
    • (1996) Nat. Med. , vol.2 , pp. 1197-1203
    • Pasqualini, R.1    Bourdoulous, S.2    Koivunen, E.3    Woods V.L., Jr.4    Ruoslahti, E.5
  • 56
    • 0031047981 scopus 로고    scopus 로고
    • Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs
    • Polte, T. R., and S. K. Hanks. 1997. Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs. J. Biol. Chem. 272:5501-5509.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5501-5509
    • Polte, T.R.1    Hanks, S.K.2
  • 57
    • 0028889436 scopus 로고
    • Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas
    • Polte, T. R., and S. K. Hanks. 1995. Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc. Natl. Acad. Sci. USA 92:10678-10682.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10678-10682
    • Polte, T.R.1    Hanks, S.K.2
  • 58
    • 0030271724 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704
    • Price, J. T., H. M. Wilson, and N. E. Haites. 1996. Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704. Eur. J. Cancer 32A:1977-1982.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 1977-1982
    • Price, J.T.1    Wilson, H.M.2    Haites, N.E.3
  • 59
    • 0030589481 scopus 로고    scopus 로고
    • Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity
    • Retta, S. F., S. T. Barry, D. R. Critchley, P. Defilippi, L. Silengo, and G. Tarone. 1996. Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. Exp. Cell Res. 229:307-317.
    • (1996) Exp. Cell Res. , vol.229 , pp. 307-317
    • Retta, S.F.1    Barry, S.T.2    Critchley, D.R.3    Defilippi, P.4    Silengo, L.5    Tarone, G.6
  • 60
    • 0030694182 scopus 로고    scopus 로고
    • Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
    • Richardson, A., R. K. Malik, J. D. Hildebrand, and J. T. Parsons. 1997. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Mol. Cell. Biol. 17:6906-6914.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6906-6914
    • Richardson, A.1    Malik, R.K.2    Hildebrand, J.D.3    Parsons, J.T.4
  • 61
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK
    • Erratum, 381:810
    • Richardson, A., and T. Parsons. 1996. A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK. Nature 380:538-540. (Erratum, 381:810.)
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parsons, T.2
  • 62
    • 0024784640 scopus 로고
    • Protein factors which regulate cell motility
    • Rosen, E. M., and I. D. Goldberg. 1989. Protein factors which regulate cell motility. In Vitro Cell Dev. Biol. 25:1079-1087.
    • (1989) In Vitro Cell Dev. Biol. , vol.25 , pp. 1079-1087
    • Rosen, E.M.1    Goldberg, I.D.2
  • 63
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon, D. S., R. Brandt, F. Ciardiello, and N. Normanno. 1995. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 19:183-232.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 64
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer, D. D., S. K. Hanks, T. Hunter, and P. van der Geer. 1994. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372:786-791.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3    Van Der Geer, P.4
  • 66
    • 0029878429 scopus 로고    scopus 로고
    • Enhancing effects of epidermal growth factor on human squamous cell carcinoma motility and matrix degradation but not growth
    • Shibata, T., T. Kawano, H. Nagayasu, K. Okumura, M. Arisue, J. Hamada, N. Takeichi, and M. Hosokawa. 1996. Enhancing effects of epidermal growth factor on human squamous cell carcinoma motility and matrix degradation but not growth. Tumour Biol. 17:168-175.
    • (1996) Tumour Biol. , vol.17 , pp. 168-175
    • Shibata, T.1    Kawano, T.2    Nagayasu, H.3    Okumura, K.4    Arisue, M.5    Hamada, J.6    Takeichi, N.7    Hosokawa, M.8
  • 68
    • 0032531732 scopus 로고    scopus 로고
    • Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
    • Sieg, D. J., D. Ilic, K. C. Jones, C. H. Damsky, T. Hunter, and D. D. Schlaepfer. 1998. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration. EMBO J. 17:5933-5947.
    • (1998) EMBO J. , vol.17 , pp. 5933-5947
    • Sieg, D.J.1    Ilic, D.2    Jones, K.C.3    Damsky, C.H.4    Hunter, T.5    Schlaepfer, D.D.6
  • 69
    • 0030669961 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates
    • Tachibana, K., T. Urano, H. Fujita, Y. Ohashi, K. Kamiguchi, S. Iwata, H. Hirai, and C. Morimoto. 1997. Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates. J. Biol. Chem. 272:29083-29090.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29083-29090
    • Tachibana, K.1    Urano, T.2    Fujita, H.3    Ohashi, Y.4    Kamiguchi, K.5    Iwata, S.6    Hirai, H.7    Morimoto, C.8
  • 71
    • 0026093671 scopus 로고
    • Endogenous secretion of epidermal growth factor peptides stimulates growth of DU145 prostate cancer cells
    • Tillotson, J. K., and D. P. Rose. 1991. Endogenous secretion of epidermal growth factor peptides stimulates growth of DU145 prostate cancer cells. Cancer Lett. 60:109-112.
    • (1991) Cancer Lett. , vol.60 , pp. 109-112
    • Tillotson, J.K.1    Rose, D.P.2
  • 73
    • 7144227965 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials
    • Voldborg, B. R., L. Damstrup, M. Spang-Thomsen, and H. S. Poulsen. 1997. Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann. Oncol. 8:1197-1206.
    • (1997) Ann. Oncol. , vol.8 , pp. 1197-1206
    • Voldborg, B.R.1    Damstrup, L.2    Spang-Thomsen, M.3    Poulsen, H.S.4
  • 74
    • 0029664531 scopus 로고    scopus 로고
    • Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases
    • Vuori, K., H. Hirai, S. Aizawa, and E. Ruoslahti. 1996. Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol. Cell. Biol. 16:2606-2613.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2606-2613
    • Vuori, K.1    Hirai, H.2    Aizawa, S.3    Ruoslahti, E.4
  • 75
    • 0032731892 scopus 로고    scopus 로고
    • Tumor invasion: Role of growth factor-induced cell motility
    • Wells, A. 2000. Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res. 78:31-101.
    • (2000) Adv. Cancer Res. , vol.78 , pp. 31-101
    • Wells, A.1
  • 76
    • 0033063774 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its inhibition in cancer therapy
    • Woodburn, J. R. 1999. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol. Ther. 82:241-250.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 241-250
    • Woodburn, J.R.1
  • 78
    • 0028822070 scopus 로고
    • In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals
    • Xie, H., T. Turner, M. H. Wang, R. K. Singh, G. P. Siegal, and A. Wells. 1995. In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals. Clin. Exp. Metastasis 13:407-419.
    • (1995) Clin. Exp. Metastasis , vol.13 , pp. 407-419
    • Xie, H.1    Turner, T.2    Wang, M.H.3    Singh, R.K.4    Siegal, G.P.5    Wells, A.6
  • 79
  • 80
    • 3543036342 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
    • Yu, D. H., C. K. Qu, O. Henegariu, X. Lu, and G. S. Feng. 1998. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J. Biol. Chem. 273:21125-21131.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21125-21131
    • Yu, D.H.1    Qu, C.K.2    Henegariu, O.3    Lu, X.4    Feng, G.S.5
  • 81
    • 0034637509 scopus 로고    scopus 로고
    • Substrate specificity of alpha vbeta 3 integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation
    • Zheng, D. Q., A. S. Woodard, G. Tallini, and L. R. Languino. 2000. Substrate specificity of alpha vbeta 3 integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation. J. Biol. Chem. 275: 24565-24574.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24565-24574
    • Zheng, D.Q.1    Woodard, A.S.2    Tallini, G.3    Languino, L.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.