Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: Synthesis

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 22, 2012, Pages 6687-6708

  Manzoni, Leonardo ^a   Belvisi, Laura ^b   Bianchi, Aldo ^c   Conti, Annalisa ^d   Drago, Carmelo ^c   De Matteo, Marilenia ^c   Ferrante, Luca ^c   Mastrangelo, Eloise ^b   Perego, Paola ^d   Potenza, Donatella ^b   Scolastico, Carlo ^c   Servida, Federica ^b   Timpano, Gabriele ^c   Vasile, Francesca ^b   Rizzo, Vincenzo ^c   Seneci, Pierfausto ^b,c  

^a CNR Consiglio Nazionale delle Ricerche   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c CISI Scrl   (Italy)

^d NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Apoptosis; IAP inhibitors; Oncology; Peptidomimetics; Smac mimetics

Indexed keywords

1 AZA 2 OXOBICYCLO[5.3.0]DECANE DERIVATIVE; HETERODIMER; HOMODIMER; INHIBITOR OF APOPTOSIS PROTEIN INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS;

BIOMIMETIC MATERIALS; DIMERIZATION; INHIBITOR OF APOPTOSIS PROTEINS; OLIGOPEPTIDES;

EID: 84867891317     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.09.020     Document Type: Article

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