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Volumn 109, Issue , 2012, Pages 485-502

Harmful and beneficial effects of inflammation after spinal cord injury. potential therapeutic implications

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EID: 84867765161     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-52137-8.00030-9     Document Type: Chapter
Times cited : (114)

References (163)
  • 1
    • 1542291023 scopus 로고    scopus 로고
    • The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse
    • Abraham K.E., McMillen D., Brewer K.L. The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse. Neuroscience 2004, 124:945-952.
    • (2004) Neuroscience , vol.124 , pp. 945-952
    • Abraham, K.E.1    McMillen, D.2    Brewer, K.L.3
  • 2
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy
    • Akassoglou K., Bauer J., Kassiotis G., et al. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am J Pathol 1998, 153:801-813.
    • (1998) Am J Pathol , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3
  • 3
    • 43049094722 scopus 로고    scopus 로고
    • Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury
    • Akdemir O., Berksoy I., Karaoglan A., et al. Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury. J Clin Neurosci 2008, 15:672-678.
    • (2008) J Clin Neurosci , vol.15 , pp. 672-678
    • Akdemir, O.1    Berksoy, I.2    Karaoglan, A.3
  • 4
    • 55849114955 scopus 로고    scopus 로고
    • The complement cascade: Yin-Yang in neuroinflammation - neuro-protection and -degeneration
    • Alexander J.J., Anderson A.J., Barnum S.R., et al. The complement cascade: Yin-Yang in neuroinflammation - neuro-protection and -degeneration. J Neurochem 2008, 107:1169-1187.
    • (2008) J Neurochem , vol.107 , pp. 1169-1187
    • Alexander, J.J.1    Anderson, A.J.2    Barnum, S.R.3
  • 5
    • 9744246880 scopus 로고    scopus 로고
    • Activation of complement pathways after contusion-induced spinal cord injury
    • Anderson A.J., Robert S., Huang W., et al. Activation of complement pathways after contusion-induced spinal cord injury. J Neurotrauma 2004, 21:1831-1846.
    • (2004) J Neurotrauma , vol.21 , pp. 1831-1846
    • Anderson, A.J.1    Robert, S.2    Huang, W.3
  • 6
    • 33750452715 scopus 로고    scopus 로고
    • Spinal cord injury triggers systemic autoimmunity: evidence for chronic B lymphocyte activation and lupus-like autoantibody synthesis
    • Ankeny D.P., Lucin K.M., Sanders V.M., et al. Spinal cord injury triggers systemic autoimmunity: evidence for chronic B lymphocyte activation and lupus-like autoantibody synthesis. J Neurochem 2006, 99:1073-1087.
    • (2006) J Neurochem , vol.99 , pp. 1073-1087
    • Ankeny, D.P.1    Lucin, K.M.2    Sanders, V.M.3
  • 7
    • 33744975502 scopus 로고    scopus 로고
    • Innate and adaptive immune responses of the central nervous system
    • Bailey S.L., Carpentier P.A., McMahon E.J., et al. Innate and adaptive immune responses of the central nervous system. Crit Rev Immunol 2006, 26:149-188.
    • (2006) Crit Rev Immunol , vol.26 , pp. 149-188
    • Bailey, S.L.1    Carpentier, P.A.2    McMahon, E.J.3
  • 8
    • 1642358379 scopus 로고    scopus 로고
    • Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats
    • Bao F., Chen Y., Dekaban G.A., et al. Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats. J Neurochem 2004, 88:1335-1344.
    • (2004) J Neurochem , vol.88 , pp. 1335-1344
    • Bao, F.1    Chen, Y.2    Dekaban, G.A.3
  • 9
    • 4444383094 scopus 로고    scopus 로고
    • An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats
    • Bao F., Chen Y., Dekaban G.A., et al. An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats. J Neurochem 2004, 90:1194-1204.
    • (2004) J Neurochem , vol.90 , pp. 1194-1204
    • Bao, F.1    Chen, Y.2    Dekaban, G.A.3
  • 10
    • 24144485411 scopus 로고    scopus 로고
    • Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats
    • Bao F., Dekaban G.A., Weaver L.C. Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats. J Neurochem 2005, 94:1361-1373.
    • (2005) J Neurochem , vol.94 , pp. 1361-1373
    • Bao, F.1    Dekaban, G.A.2    Weaver, L.C.3
  • 11
    • 56749098090 scopus 로고    scopus 로고
    • An integrin inhibiting molecule decreases oxidative damage and improves neurological function after spinal cord injury
    • Bao F., Chen Y., Schneider K.A., et al. An integrin inhibiting molecule decreases oxidative damage and improves neurological function after spinal cord injury. Exp Neurol 2008, 214:160-167.
    • (2008) Exp Neurol , vol.214 , pp. 160-167
    • Bao, F.1    Chen, Y.2    Schneider, K.A.3
  • 12
    • 0030842973 scopus 로고    scopus 로고
    • Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: an in situ hybridization study
    • Bartholdi D., Schwab M.E. Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: an in situ hybridization study. Eur J Neurosci 1997, 9:1422-1438.
    • (1997) Eur J Neurosci , vol.9 , pp. 1422-1438
    • Bartholdi, D.1    Schwab, M.E.2
  • 13
    • 23744457144 scopus 로고    scopus 로고
    • The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats
    • discussion 220
    • Barut S., Unlu Y.A., Karaoglan A., et al. The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats. Surg Neurol 2005, 64:213-220. discussion 220.
    • (2005) Surg Neurol , vol.64 , pp. 213-220
    • Barut, S.1    Unlu, Y.A.2    Karaoglan, A.3
  • 14
    • 0032816454 scopus 로고    scopus 로고
    • The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration
    • Bavetta S., Hamlyn P.J., Burnstock G., et al. The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. Exp Neurol 1999, 158:382-393.
    • (1999) Exp Neurol , vol.158 , pp. 382-393
    • Bavetta, S.1    Hamlyn, P.J.2    Burnstock, G.3
  • 15
    • 0031901842 scopus 로고    scopus 로고
    • The cytokine network of wallerian degeneration: IL-10 and GM-CSF
    • Be'eri H., Reichert F., Saada A., et al. The cytokine network of wallerian degeneration: IL-10 and GM-CSF. Eur J Neurosci 1998, 10:2707-2713.
    • (1998) Eur J Neurosci , vol.10 , pp. 2707-2713
    • Be'eri, H.1    Reichert, F.2    Saada, A.3
  • 16
  • 17
    • 0032739262 scopus 로고    scopus 로고
    • Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats
    • Bethea J.R., Nagashima H., Acosta M.C., et al. Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats. J Neurotrauma 1999, 16:851-863.
    • (1999) J Neurotrauma , vol.16 , pp. 851-863
    • Bethea, J.R.1    Nagashima, H.2    Acosta, M.C.3
  • 18
    • 33845667413 scopus 로고    scopus 로고
    • Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages
    • Bouhy D., Malgrange B., Multon S., et al. Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages. FASEB J 2006, 20:1239-1241.
    • (2006) FASEB J , vol.20 , pp. 1239-1241
    • Bouhy, D.1    Malgrange, B.2    Multon, S.3
  • 19
    • 80755181221 scopus 로고    scopus 로고
    • Inhibition of the Ca(2)(+)-dependent K(+) channel, KCNN4/KCa3.1, improves tissue protection and locomotor recovery after spinal cord injury
    • Bouhy D., Ghasemlou N., Lively S., Redensek A., et al. Inhibition of the Ca(2)(+)-dependent K(+) channel, KCNN4/KCa3.1, improves tissue protection and locomotor recovery after spinal cord injury. J Neurosci 2011, 31:16298-16308.
    • (2011) J Neurosci , vol.31 , pp. 16298-16308
    • Bouhy, D.1    Ghasemlou, N.2    Lively, S.3    Redensek, A.4
  • 20
    • 31544466262 scopus 로고    scopus 로고
    • Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis
    • Boven L.A., Van Meurs M., Van Zwam M., et al. Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis. Brain 2006, 129:517-526.
    • (2006) Brain , vol.129 , pp. 517-526
    • Boven, L.A.1    Van Meurs, M.2    Van Zwam, M.3
  • 21
    • 22344431751 scopus 로고    scopus 로고
    • Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    • Brambilla R., Bracchi-Ricard V., Hu W.H., et al. Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J Exp Med 2005, 202:145-156.
    • (2005) J Exp Med , vol.202 , pp. 145-156
    • Brambilla, R.1    Bracchi-Ricard, V.2    Hu, W.H.3
  • 22
    • 0025191219 scopus 로고
    • Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme
    • Bredt D.S., Snyder S.H. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci U S A 1990, 87:682-685.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 682-685
    • Bredt, D.S.1    Snyder, S.H.2
  • 23
    • 0030972140 scopus 로고    scopus 로고
    • The role of macrophages in Wallerian degeneration
    • Bruck W. The role of macrophages in Wallerian degeneration. Brain Pathol 1997, 7:741-752.
    • (1997) Brain Pathol , vol.7 , pp. 741-752
    • Bruck, W.1
  • 24
    • 0036260089 scopus 로고    scopus 로고
    • Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis
    • Brundula V., Rewcastle N.B., Metz L.M., et al. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain 2002, 125:1297-1308.
    • (2002) Brain , vol.125 , pp. 1297-1308
    • Brundula, V.1    Rewcastle, N.B.2    Metz, L.M.3
  • 25
    • 0027343542 scopus 로고
    • Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination
    • Bunge R.P., Puckett W.R., Becerra J.L., et al. Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination. Adv Neurol 1993, 59:75-89.
    • (1993) Adv Neurol , vol.59 , pp. 75-89
    • Bunge, R.P.1    Puckett, W.R.2    Becerra, J.L.3
  • 26
    • 0037468853 scopus 로고    scopus 로고
    • Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones
    • Campbell D.S., Holt C.E. Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones. Neuron 2003, 37:939-952.
    • (2003) Neuron , vol.37 , pp. 939-952
    • Campbell, D.S.1    Holt, C.E.2
  • 27
    • 84860146607 scopus 로고    scopus 로고
    • Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury
    • Casha S., Zygun D., McGowan M.D., Bains I., et al. Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury. Brain 2012, 135:1224-1236.
    • (2012) Brain , vol.135 , pp. 1224-1236
    • Casha, S.1    Zygun, D.2    McGowan, M.D.3    Bains, I.4
  • 28
    • 0036264281 scopus 로고    scopus 로고
    • Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment
    • Chatzipanteli K., Garcia R., Marcillo A.E., et al. Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment. J Neurotrauma 2002, 19:639-651.
    • (2002) J Neurotrauma , vol.19 , pp. 639-651
    • Chatzipanteli, K.1    Garcia, R.2    Marcillo, A.E.3
  • 29
    • 35348819417 scopus 로고    scopus 로고
    • Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models
    • Choi Y., Kim H.S., Shin K.Y., et al. Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models. Neuropsychopharmacology 2007, 32:2393-2404.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2393-2404
    • Choi, Y.1    Kim, H.S.2    Shin, K.Y.3
  • 30
    • 0029794989 scopus 로고    scopus 로고
    • Cerebroprotective effects of aminoguanidine in a rodent model of stroke
    • Cockroft K.M., Meistrell M., Zimmerman G.A., et al. Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke 1996, 27:1393-1398.
    • (1996) Stroke , vol.27 , pp. 1393-1398
    • Cockroft, K.M.1    Meistrell, M.2    Zimmerman, G.A.3
  • 31
    • 16844382592 scopus 로고    scopus 로고
    • Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury
    • Colak A., Karaoglan A., Barut S., et al. Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury. J Neurosurg Spine 2005, 2:327-334.
    • (2005) J Neurosurg Spine , vol.2 , pp. 327-334
    • Colak, A.1    Karaoglan, A.2    Barut, S.3
  • 32
    • 42449110295 scopus 로고    scopus 로고
    • Mechanisms of leukocyte migration across the blood-retina barrier
    • Crane I.J., Liversidge J. Mechanisms of leukocyte migration across the blood-retina barrier. Springer Semin Immunopathol 2008, 30:165-177.
    • (2008) Springer Semin Immunopathol , vol.30 , pp. 165-177
    • Crane, I.J.1    Liversidge, J.2
  • 33
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • Crowe M.J., Bresnahan J.C., Shuman S.L., et al. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997, 3:73-76.
    • (1997) Nat Med , vol.3 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3
  • 34
    • 39449092068 scopus 로고    scopus 로고
    • Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma
    • Cuzzocrea S., Genovese T., Mazzon E., et al. Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. Shock 2008, 29:362-371.
    • (2008) Shock , vol.29 , pp. 362-371
    • Cuzzocrea, S.1    Genovese, T.2    Mazzon, E.3
  • 35
    • 0042858516 scopus 로고    scopus 로고
    • Molecular approaches to spinal cord repair
    • David S., Lacroix S. Molecular approaches to spinal cord repair. Annu Rev Neurosci 2003, 26:411-440.
    • (2003) Annu Rev Neurosci , vol.26 , pp. 411-440
    • David, S.1    Lacroix, S.2
  • 36
    • 0025093295 scopus 로고
    • Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system
    • David S., Bouchard C., Tsatas O., et al. Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system. Neuron 1990, 5:463-469.
    • (1990) Neuron , vol.5 , pp. 463-469
    • David, S.1    Bouchard, C.2    Tsatas, O.3
  • 37
    • 11144354396 scopus 로고    scopus 로고
    • Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury
    • Demjen D., Klussmann S., Kleber S., et al. Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. Nat Med 2004, 10:389-395.
    • (2004) Nat Med , vol.10 , pp. 389-395
    • Demjen, D.1    Klussmann, S.2    Kleber, S.3
  • 38
    • 0036703599 scopus 로고    scopus 로고
    • Rho signaling pathway targeted to promote spinal cord repair
    • Dergham P., Ellezam B., Essagian C., et al. Rho signaling pathway targeted to promote spinal cord repair. J Neurosci 2002, 22:6570-6577.
    • (2002) J Neurosci , vol.22 , pp. 6570-6577
    • Dergham, P.1    Ellezam, B.2    Essagian, C.3
  • 39
    • 0036499074 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis
    • Diab A., Deng C., Smith J.D., et al. Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. J Immunol 2002, 168:2508-2515.
    • (2002) J Immunol , vol.168 , pp. 2508-2515
    • Diab, A.1    Deng, C.2    Smith, J.D.3
  • 40
    • 0037154659 scopus 로고    scopus 로고
    • Constitutive and inducible nitric oxide synthase activities after spinal cord contusion in rats
    • Diaz-Ruiz A., Ibarra A., Perez-Severiano F., et al. Constitutive and inducible nitric oxide synthase activities after spinal cord contusion in rats. Neurosci Lett 2002, 319:129-132.
    • (2002) Neurosci Lett , vol.319 , pp. 129-132
    • Diaz-Ruiz, A.1    Ibarra, A.2    Perez-Severiano, F.3
  • 41
    • 61749090687 scopus 로고    scopus 로고
    • Significant recovery of motor function in a patient with complete T7 paraplegia receiving etanercept
    • Dinomais M., Stana L., Egon G., et al. Significant recovery of motor function in a patient with complete T7 paraplegia receiving etanercept. J Rehabil Med 2009, 41:286-288.
    • (2009) J Rehabil Med , vol.41 , pp. 286-288
    • Dinomais, M.1    Stana, L.2    Egon, G.3
  • 42
    • 38749086493 scopus 로고    scopus 로고
    • Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
    • Donnelly D.J., Popovich P.G. Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol 2008, 209:378-388.
    • (2008) Exp Neurol , vol.209 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 43
    • 0042171820 scopus 로고    scopus 로고
    • Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
    • Dubreuil C.I., Winton M.J., McKerracher L. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J Cell Biol 2003, 162:233-243.
    • (2003) J Cell Biol , vol.162 , pp. 233-243
    • Dubreuil, C.I.1    Winton, M.J.2    McKerracher, L.3
  • 44
    • 0037266937 scopus 로고    scopus 로고
    • Response of chemokine antagonists to inflammation in injured spinal cord
    • Eng L.F., Lee Y.L. Response of chemokine antagonists to inflammation in injured spinal cord. Neurochem Res 2003, 28:95-100.
    • (2003) Neurochem Res , vol.28 , pp. 95-100
    • Eng, L.F.1    Lee, Y.L.2
  • 45
    • 0026511216 scopus 로고
    • The effect of direct current field polarity on recovery after acute experimental spinal cord injury
    • Fehlings M.G., Tator C.H. The effect of direct current field polarity on recovery after acute experimental spinal cord injury. Brain Res 1992, 579:32-42.
    • (1992) Brain Res , vol.579 , pp. 32-42
    • Fehlings, M.G.1    Tator, C.H.2
  • 46
    • 79955961172 scopus 로고    scopus 로고
    • A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury
    • Fehlings M.G., Theodore N., Harrop J., Maurais G., et al. A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury. J Neurotrauma 2011, 28:787-796.
    • (2011) J Neurotrauma , vol.28 , pp. 787-796
    • Fehlings, M.G.1    Theodore, N.2    Harrop, J.3    Maurais, G.4
  • 47
    • 0032520762 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene
    • Fenyk-Melody J.E., Garrison A.E., Brunnert S.R., et al. Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene. J Immunol 1998, 160:2940-2946.
    • (1998) J Immunol , vol.160 , pp. 2940-2946
    • Fenyk-Melody, J.E.1    Garrison, A.E.2    Brunnert, S.R.3
  • 48
    • 56149092503 scopus 로고    scopus 로고
    • Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane
    • Ferguson A.R., Christensen R.N., Gensel J.C., et al. Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane. J Neurosci 2008, 28:11391-11400.
    • (2008) J Neurosci , vol.28 , pp. 11391-11400
    • Ferguson, A.R.1    Christensen, R.N.2    Gensel, J.C.3
  • 49
    • 39649101076 scopus 로고    scopus 로고
    • Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration
    • Fischer D., Hauk T.G., Muller A., et al. Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration. Mol Cell Neurosci 2008, 37:471-479.
    • (2008) Mol Cell Neurosci , vol.37 , pp. 471-479
    • Fischer, D.1    Hauk, T.G.2    Muller, A.3
  • 50
    • 33845332735 scopus 로고    scopus 로고
    • The cellular inflammatory response in human spinal cords after injury
    • Fleming J.C., Norenberg M.D., Ramsay D.A., et al. The cellular inflammatory response in human spinal cords after injury. Brain 2006, 129:3249-3269.
    • (2006) Brain , vol.129 , pp. 3249-3269
    • Fleming, J.C.1    Norenberg, M.D.2    Ramsay, D.A.3
  • 51
    • 56749170671 scopus 로고    scopus 로고
    • Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function
    • Fleming J.C., Bao F., Chen Y., et al. Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function. Exp Neurol 2008, 214:147-159.
    • (2008) Exp Neurol , vol.214 , pp. 147-159
    • Fleming, J.C.1    Bao, F.2    Chen, Y.3
  • 52
    • 23444436221 scopus 로고    scopus 로고
    • Microglia Kv1.3 channels contribute to their ability to kill neurons
    • Fordyce C.B., Jagasia R., Zhu X., et al. Microglia Kv1.3 channels contribute to their ability to kill neurons. J Neurosci 2005, 25:7139-7149.
    • (2005) J Neurosci , vol.25 , pp. 7139-7149
    • Fordyce, C.B.1    Jagasia, R.2    Zhu, X.3
  • 53
    • 0037443069 scopus 로고    scopus 로고
    • Rho kinase inhibition enhances axonal regeneration in the injured CNS
    • Fournier A.E., Takizawa B.T., Strittmatter S.M. Rho kinase inhibition enhances axonal regeneration in the injured CNS. J Neurosci 2003, 23:1416-1423.
    • (2003) J Neurosci , vol.23 , pp. 1416-1423
    • Fournier, A.E.1    Takizawa, B.T.2    Strittmatter, S.M.3
  • 54
    • 0021333502 scopus 로고
    • Myelin breakdown and elimination in the posterior funiculus of the adult cat after dorsal rhizotomy: a light and electron microscopic qualitative and quantitative study
    • Franson P., Ronnevi L.O. Myelin breakdown and elimination in the posterior funiculus of the adult cat after dorsal rhizotomy: a light and electron microscopic qualitative and quantitative study. J Comp Neurol 1984, 223:138-151.
    • (1984) J Comp Neurol , vol.223 , pp. 138-151
    • Franson, P.1    Ronnevi, L.O.2
  • 55
    • 33847162723 scopus 로고    scopus 로고
    • A role for Nogo receptor in macrophage clearance from injured peripheral nerve
    • Fry E.J., Ho C., David S. A role for Nogo receptor in macrophage clearance from injured peripheral nerve. Neuron 2007, 53:649-662.
    • (2007) Neuron , vol.53 , pp. 649-662
    • Fry, E.J.1    Ho, C.2    David, S.3
  • 56
    • 58149390112 scopus 로고    scopus 로고
    • Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury
    • Galvan M.D., Luchetti S., Burgos A.M., et al. Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. J Neurosci 2008, 28:13876-13888.
    • (2008) J Neurosci , vol.28 , pp. 13876-13888
    • Galvan, M.D.1    Luchetti, S.2    Burgos, A.M.3
  • 57
    • 33644768268 scopus 로고    scopus 로고
    • Immunomodulatory effects of etanercept in an experimental model of spinal cord injury
    • Genovese T., Mazzon E., Crisafulli C., et al. Immunomodulatory effects of etanercept in an experimental model of spinal cord injury. J Pharmacol Exp Ther 2006, 316:1006-1016.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 1006-1016
    • Genovese, T.1    Mazzon, E.2    Crisafulli, C.3
  • 58
    • 37549029154 scopus 로고    scopus 로고
    • TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome
    • Genovese T., Mazzon E., Crisafulli C., et al. TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome. Shock 2008, 29:32-41.
    • (2008) Shock , vol.29 , pp. 32-41
    • Genovese, T.1    Mazzon, E.2    Crisafulli, C.3
  • 59
    • 61349140638 scopus 로고    scopus 로고
    • Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice
    • Genovese T., Esposito E., Mazzon E., et al. Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice. J Neurochem 2009, 108:1360-1372.
    • (2009) J Neurochem , vol.108 , pp. 1360-1372
    • Genovese, T.1    Esposito, E.2    Mazzon, E.3
  • 60
    • 0027970246 scopus 로고
    • Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model
    • George R., Griffin J.W. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model. Exp Neurol 1994, 129:225-236.
    • (1994) Exp Neurol , vol.129 , pp. 225-236
    • George, R.1    Griffin, J.W.2
  • 61
    • 26244466050 scopus 로고    scopus 로고
    • Tissue displacement and impact force are important contributors to outcome after spinal cord contusion injury
    • Ghasemlou N., Kerr B.J., David S. Tissue displacement and impact force are important contributors to outcome after spinal cord contusion injury. Exp Neurol 2005, 196:9-17.
    • (2005) Exp Neurol , vol.196 , pp. 9-17
    • Ghasemlou, N.1    Kerr, B.J.2    David, S.3
  • 62
    • 0033985419 scopus 로고    scopus 로고
    • Chemokine antagonist infusion attenuates cellular infiltration following spinal cord contusion injury in rat
    • Ghirnikar R.S., Lee Y.L., Eng L.F. Chemokine antagonist infusion attenuates cellular infiltration following spinal cord contusion injury in rat. J Neurosci Res 2000, 59:63-73.
    • (2000) J Neurosci Res , vol.59 , pp. 63-73
    • Ghirnikar, R.S.1    Lee, Y.L.2    Eng, L.F.3
  • 63
    • 4444244404 scopus 로고    scopus 로고
    • Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury
    • Glaser J., Gonzalez R., Perreau V.M., et al. Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury. J Neurosci Res 2004, 77:701-708.
    • (2004) J Neurosci Res , vol.77 , pp. 701-708
    • Glaser, J.1    Gonzalez, R.2    Perreau, V.M.3
  • 64
    • 33748564678 scopus 로고    scopus 로고
    • Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury
    • Glaser J., Gonzalez R., Sadr E., et al. Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury. J Neurosci Res 2006, 84:724-734.
    • (2006) J Neurosci Res , vol.84 , pp. 724-734
    • Glaser, J.1    Gonzalez, R.2    Sadr, E.3
  • 65
    • 35048890497 scopus 로고    scopus 로고
    • Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice
    • Gonzalez R., Hickey M.J., Espinosa J.M., et al. Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice. Regen Med 2007, 2:771-783.
    • (2007) Regen Med , vol.2 , pp. 771-783
    • Gonzalez, R.1    Hickey, M.J.2    Espinosa, J.M.3
  • 66
    • 36148960127 scopus 로고    scopus 로고
    • Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
    • Gordon P.H., Moore D.H., Miller R.G., et al. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol 2007, 6:1045-1053.
    • (2007) Lancet Neurol , vol.6 , pp. 1045-1053
    • Gordon, P.H.1    Moore, D.H.2    Miller, R.G.3
  • 67
    • 2142821430 scopus 로고    scopus 로고
    • Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
    • Gris D., Marsh D.R., Oatway M.A., et al. Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function. J Neurosci 2004, 24:4043-4051.
    • (2004) J Neurosci , vol.24 , pp. 4043-4051
    • Gris, D.1    Marsh, D.R.2    Oatway, M.A.3
  • 68
    • 0028922422 scopus 로고
    • Nitric oxide: pathophysiological mechanisms
    • Gross S.S., Wolin M.S. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol 1995, 57:737-769.
    • (1995) Annu Rev Physiol , vol.57 , pp. 737-769
    • Gross, S.S.1    Wolin, M.S.2
  • 69
    • 0036908651 scopus 로고    scopus 로고
    • The many faces of tumor necrosis factor in stroke
    • Hallenbeck J.M. The many faces of tumor necrosis factor in stroke. Nat Med 2002, 8:1363-1368.
    • (2002) Nat Med , vol.8 , pp. 1363-1368
    • Hallenbeck, J.M.1
  • 70
    • 0026323665 scopus 로고
    • Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein
    • Hevel J.M., White K.A., Marletta M.A. Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein. J Biol Chem 1991, 266:22789-22791.
    • (1991) J Biol Chem , vol.266 , pp. 22789-22791
    • Hevel, J.M.1    White, K.A.2    Marletta, M.A.3
  • 71
    • 35648944690 scopus 로고    scopus 로고
    • A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury
    • Huang W.L., King V.R., Curran O.E., et al. A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. Brain 2007, 130:3004-3019.
    • (2007) Brain , vol.130 , pp. 3004-3019
    • Huang, W.L.1    King, V.R.2    Curran, O.E.3
  • 72
    • 34247877666 scopus 로고    scopus 로고
    • GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins
    • Huang X., Choi J.K., Park S.R., et al. GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins. Neurosci Res 2007, 58:50-57.
    • (2007) Neurosci Res , vol.58 , pp. 50-57
    • Huang, X.1    Choi, J.K.2    Park, S.R.3
  • 73
    • 58149302834 scopus 로고    scopus 로고
    • GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury
    • Huang X., Kim J.M., Kong T.H., et al. GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury. J Neurol Sci 2009, 277:87-97.
    • (2009) J Neurol Sci , vol.277 , pp. 87-97
    • Huang, X.1    Kim, J.M.2    Kong, T.H.3
  • 74
    • 0342647473 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: an inappropriate standard of care
    • Hurlbert R.J. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg 2000, 93:1-7.
    • (2000) J Neurosurg , vol.93 , pp. 1-7
    • Hurlbert, R.J.1
  • 75
    • 33646790870 scopus 로고    scopus 로고
    • Strategies of medical intervention in the management of acute spinal cord injury
    • discussion S36
    • Hurlbert R.J. Strategies of medical intervention in the management of acute spinal cord injury. Spine 2006, 31:S16-S21. discussion S36.
    • (2006) Spine , vol.31
    • Hurlbert, R.J.1
  • 76
    • 42049104347 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: 5-year practice reversal
    • Hurlbert R.J., Hamilton M.G. Methylprednisolone for acute spinal cord injury: 5-year practice reversal. Can J Neurol Sci 2008, 35:41-45.
    • (2008) Can J Neurol Sci , vol.35 , pp. 41-45
    • Hurlbert, R.J.1    Hamilton, M.G.2
  • 77
    • 0031020172 scopus 로고    scopus 로고
    • Bright and dark sides of nitric oxide in ischemic brain injury
    • Iadecola C. Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci 1997, 20:132-139.
    • (1997) Trends Neurosci , vol.20 , pp. 132-139
    • Iadecola, C.1
  • 78
    • 0029294575 scopus 로고
    • Inducible nitric oxide synthase gene expression in brain following cerebral ischemia
    • Iadecola C., Zhang F., Xu S., et al. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab 1995, 15:378-384.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 378-384
    • Iadecola, C.1    Zhang, F.2    Xu, S.3
  • 79
    • 0034076496 scopus 로고    scopus 로고
    • Traumatic spinal cord injury produced by controlled contusion in mouse
    • Jakeman L.B., Guan Z., Wei P., et al. Traumatic spinal cord injury produced by controlled contusion in mouse. J Neurotrauma 2000, 17:299-319.
    • (2000) J Neurotrauma , vol.17 , pp. 299-319
    • Jakeman, L.B.1    Guan, Z.2    Wei, P.3
  • 80
    • 6344250448 scopus 로고    scopus 로고
    • Neuropathology: the foundation for new treatments in spinal cord injury
    • Kakulas B.A. Neuropathology: the foundation for new treatments in spinal cord injury. Spinal Cord 2004, 42:549-563.
    • (2004) Spinal Cord , vol.42 , pp. 549-563
    • Kakulas, B.A.1
  • 81
    • 66549114353 scopus 로고    scopus 로고
    • Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis
    • Kalyvas A., Baskakis C., Magrioti V., et al. Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis. Brain 2009, 132:1221-1235.
    • (2009) Brain , vol.132 , pp. 1221-1235
    • Kalyvas, A.1    Baskakis, C.2    Magrioti, V.3
  • 82
    • 39849083520 scopus 로고    scopus 로고
    • Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
    • Kaushal V., Schlichter L.C. Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J Neurosci 2008, 28:2221-2230.
    • (2008) J Neurosci , vol.28 , pp. 2221-2230
    • Kaushal, V.1    Schlichter, L.C.2
  • 83
    • 33846122620 scopus 로고    scopus 로고
    • The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration
    • Kaushal V., Koeberle P.D., Wang Y., et al. The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. J Neurosci 2007, 27:234-244.
    • (2007) J Neurosci , vol.27 , pp. 234-244
    • Kaushal, V.1    Koeberle, P.D.2    Wang, Y.3
  • 84
    • 38949195067 scopus 로고    scopus 로고
    • The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury
    • Kerr B.J., Girolami E.I., Ghasemlou N., et al. The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. Glia 2008, 56:436-448.
    • (2008) Glia , vol.56 , pp. 436-448
    • Kerr, B.J.1    Girolami, E.I.2    Ghasemlou, N.3
  • 85
    • 30144445614 scopus 로고    scopus 로고
    • Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury
    • Kigerl K.A., McGaughy V.M., Popovich P.G. Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury. J Comp Neurol 2006, 494:578-594.
    • (2006) J Comp Neurol , vol.494 , pp. 578-594
    • Kigerl, K.A.1    McGaughy, V.M.2    Popovich, P.G.3
  • 86
    • 0035449479 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury
    • Kim G.M., Xu J., Xu J., et al. Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury. J Neurosci 2001, 21:6617-6625.
    • (2001) J Neurosci , vol.21 , pp. 6617-6625
    • Kim, G.M.1    Xu, J.2    Xu, J.3
  • 87
    • 34447128135 scopus 로고    scopus 로고
    • Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species
    • Kunz A., Park L., Abe T., et al. Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species. J Neurosci 2007, 27:7083-7093.
    • (2007) J Neurosci , vol.27 , pp. 7083-7093
    • Kunz, A.1    Park, L.2    Abe, T.3
  • 88
    • 58849147077 scopus 로고    scopus 로고
    • Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia
    • Lambert C., Desbarats J., Arbour N., et al. Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia. J Immunol 2008, 181:8288-8297.
    • (2008) J Immunol , vol.181 , pp. 8288-8297
    • Lambert, C.1    Desbarats, J.2    Arbour, N.3
  • 89
    • 0031595870 scopus 로고    scopus 로고
    • Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
    • Lawrence C.B., Allan S.M., Rothwell N.J. Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur J Neurosci 1998, 10:1188-1195.
    • (1998) Eur J Neurosci , vol.10 , pp. 1188-1195
    • Lawrence, C.B.1    Allan, S.M.2    Rothwell, N.J.3
  • 90
    • 0033964038 scopus 로고    scopus 로고
    • Cytokine chemokine expression in contused rat spinal cord
    • Lee Y.L., Shih K., Bao P., et al. Cytokine chemokine expression in contused rat spinal cord. Neurochem Int 2000, 36:417-425.
    • (2000) Neurochem Int , vol.36 , pp. 417-425
    • Lee, Y.L.1    Shih, K.2    Bao, P.3
  • 91
    • 0034659957 scopus 로고    scopus 로고
    • Lens injury stimulates axon regeneration in the mature rat optic nerve
    • Leon S., Yin Y., Nguyen J., et al. Lens injury stimulates axon regeneration in the mature rat optic nerve. J Neurosci 2000, 20:4615-4626.
    • (2000) J Neurosci , vol.20 , pp. 4615-4626
    • Leon, S.1    Yin, Y.2    Nguyen, J.3
  • 92
    • 0034638259 scopus 로고    scopus 로고
    • Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury
    • Li M., Ona V.O., Chen M., et al. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience 2000, 99:333-342.
    • (2000) Neuroscience , vol.99 , pp. 333-342
    • Li, M.1    Ona, V.O.2    Chen, M.3
  • 93
    • 0022205428 scopus 로고
    • Ultrastructural sequence of myelin breakdown during Wallerian degeneration in the rat optic nerve
    • Liu K.M., Shen C.L. Ultrastructural sequence of myelin breakdown during Wallerian degeneration in the rat optic nerve. Cell Tissue Res 1985, 242:245-256.
    • (1985) Cell Tissue Res , vol.242 , pp. 245-256
    • Liu, K.M.1    Shen, C.L.2
  • 94
    • 0029744418 scopus 로고    scopus 로고
    • Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat
    • Loddick S.A., Rothwell N.J. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 1996, 16:932-940.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 932-940
    • Loddick, S.A.1    Rothwell, N.J.2
  • 95
    • 27444436221 scopus 로고    scopus 로고
    • FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat
    • López-Vales R., Garcia-Alias G., Fores J., et al. FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. J Neurosci Res 2005, 81:827-836.
    • (2005) J Neurosci Res , vol.81 , pp. 827-836
    • López-Vales, R.1    Garcia-Alias, G.2    Fores, J.3
  • 96
    • 33646592866 scopus 로고    scopus 로고
    • Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury
    • López-Vales R., Garcia-Alias G., Guzman-Lenis M.S., et al. Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. Spine 2006, 31:1100-1106.
    • (2006) Spine , vol.31 , pp. 1100-1106
    • López-Vales, R.1    Garcia-Alias, G.2    Guzman-Lenis, M.S.3
  • 97
    • 54949138120 scopus 로고    scopus 로고
    • Intracellular phospholipase A(2) group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury
    • López-Vales R., Navarro X., Shimizu T., et al. Intracellular phospholipase A(2) group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury. Brain 2008, 131:2620-2631.
    • (2008) Brain , vol.131 , pp. 2620-2631
    • López-Vales, R.1    Navarro, X.2    Shimizu, T.3
  • 98
    • 82655171632 scopus 로고    scopus 로고
    • Phospholipase A2 superfamily members play divergent roles after spinal cord injury
    • López-Vales R., Ghasemlou N., Redensek A., Kerr B.J., et al. Phospholipase A2 superfamily members play divergent roles after spinal cord injury. FASEB J. 2011, 25:4240-4252.
    • (2011) FASEB J. , vol.25 , pp. 4240-4252
    • López-Vales, R.1    Ghasemlou, N.2    Redensek, A.3    Kerr, B.J.4
  • 99
    • 57349179914 scopus 로고    scopus 로고
    • Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury
    • Lord-Fontaine S., Yang F., Diep Q., et al. Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury. J Neurotrauma 2008, 25:1309-1322.
    • (2008) J Neurotrauma , vol.25 , pp. 1309-1322
    • Lord-Fontaine, S.1    Yang, F.2    Diep, Q.3
  • 100
    • 0037097215 scopus 로고    scopus 로고
    • Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion
    • Ma M., Wei T., Boring L., et al. Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion. J Neurosci Res 2002, 68:691-702.
    • (2002) J Neurosci Res , vol.68 , pp. 691-702
    • Ma, M.1    Wei, T.2    Boring, L.3
  • 101
    • 0032411557 scopus 로고    scopus 로고
    • Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats
    • Madsen J.R., MacDonald P., Irwin N., et al. Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp Neurol 1998, 154:673-683.
    • (1998) Exp Neurol , vol.154 , pp. 673-683
    • Madsen, J.R.1    MacDonald, P.2    Irwin, N.3
  • 102
    • 0025297592 scopus 로고
    • Production of hemopoietic colony-stimulating factors by astrocytes
    • Malipiero U.V., Frei K., Fontana A. Production of hemopoietic colony-stimulating factors by astrocytes. J Immunol 1990, 144:3816-3821.
    • (1990) J Immunol , vol.144 , pp. 3816-3821
    • Malipiero, U.V.1    Frei, K.2    Fontana, A.3
  • 103
    • 67349208852 scopus 로고    scopus 로고
    • Erythropoietin in spinal cord injury
    • Matis G.K., Birbilis T.A. Erythropoietin in spinal cord injury. Eur Spine J 2009, 18:314-323.
    • (2009) Eur Spine J , vol.18 , pp. 314-323
    • Matis, G.K.1    Birbilis, T.A.2
  • 104
    • 7044227446 scopus 로고    scopus 로고
    • Easing the brakes on spinal cord repair
    • McKerracher L., David S. Easing the brakes on spinal cord repair. Nat Med 2004, 10:1052-1053.
    • (2004) Nat Med , vol.10 , pp. 1052-1053
    • McKerracher, L.1    David, S.2
  • 105
    • 11144354138 scopus 로고    scopus 로고
    • Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis
    • Metz L.M., Zhang Y., Yeung M., et al. Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis. Ann Neurol 2004, 55:756.
    • (2004) Ann Neurol , vol.55 , pp. 756
    • Metz, L.M.1    Zhang, Y.2    Yeung, M.3
  • 106
    • 0025784834 scopus 로고
    • Endogenous nitric oxide: physiology, pathology and clinical relevance
    • Moncada S., Higgs E.A. Endogenous nitric oxide: physiology, pathology and clinical relevance. Eur J Clin Invest 1991, 21:361-374.
    • (1991) Eur J Clin Invest , vol.21 , pp. 361-374
    • Moncada, S.1    Higgs, E.A.2
  • 107
    • 36749004288 scopus 로고    scopus 로고
    • Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation
    • Muller A., Hauk T.G., Fischer D. Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation. Brain 2007, 130:3308-3320.
    • (2007) Brain , vol.130 , pp. 3308-3320
    • Muller, A.1    Hauk, T.G.2    Fischer, D.3
  • 108
    • 1142287412 scopus 로고    scopus 로고
    • Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
    • Muppidi J.R., Siegel R.M. Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat Immunol 2004, 5:182-189.
    • (2004) Nat Immunol , vol.5 , pp. 182-189
    • Muppidi, J.R.1    Siegel, R.M.2
  • 109
    • 0038101299 scopus 로고    scopus 로고
    • Prostaglandin E1 reduces compression trauma-induced spinal cord injury in rats mainly by inhibiting neutrophil activation
    • Naruo S., Okajima K., Taoka Y., et al. Prostaglandin E1 reduces compression trauma-induced spinal cord injury in rats mainly by inhibiting neutrophil activation. J Neurotrauma 2003, 20:221-228.
    • (2003) J Neurotrauma , vol.20 , pp. 221-228
    • Naruo, S.1    Okajima, K.2    Taoka, Y.3
  • 110
    • 0034856386 scopus 로고    scopus 로고
    • IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury
    • Nesic O., Xu G.Y., McAdoo D., et al. IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury. J Neurotrauma 2001, 18:947-956.
    • (2001) J Neurotrauma , vol.18 , pp. 947-956
    • Nesic, O.1    Xu, G.Y.2    McAdoo, D.3
  • 111
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson D.W. From bench to clinic with apoptosis-based therapeutic agents. Nature 2000, 407:810-816.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 112
    • 1942425481 scopus 로고    scopus 로고
    • The pathology of human spinal cord injury: defining the problems
    • Norenberg M.D., Smith J., Marcillo A. The pathology of human spinal cord injury: defining the problems. J Neurotrauma 2004, 21:429-440.
    • (2004) J Neurotrauma , vol.21 , pp. 429-440
    • Norenberg, M.D.1    Smith, J.2    Marcillo, A.3
  • 113
    • 12744277932 scopus 로고    scopus 로고
    • Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord
    • Oatway M.A., Chen Y., Bruce J.C., et al. Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord. J Neurosci 2005, 25:637-647.
    • (2005) J Neurosci , vol.25 , pp. 637-647
    • Oatway, M.A.1    Chen, Y.2    Bruce, J.C.3
  • 114
    • 0035384902 scopus 로고    scopus 로고
    • MIP-1alpha, MCP-1, GM-CSF, and TNF-alpha control the immune cell response that mediates rapid phagocytosis of myelin from the adult mouse spinal cord
    • Ousman S.S., David S. MIP-1alpha, MCP-1, GM-CSF, and TNF-alpha control the immune cell response that mediates rapid phagocytosis of myelin from the adult mouse spinal cord. J Neurosci 2001, 21:4649-4656.
    • (2001) J Neurosci , vol.21 , pp. 4649-4656
    • Ousman, S.S.1    David, S.2
  • 115
    • 0036435517 scopus 로고    scopus 로고
    • Therapeutic strategies targeting caspase inhibition following spinal cord injury in rats
    • Ozawa H., Keane R.W., Marcillo A.E., et al. Therapeutic strategies targeting caspase inhibition following spinal cord injury in rats. Exp Neurol 2002, 177:306-313.
    • (2002) Exp Neurol , vol.177 , pp. 306-313
    • Ozawa, H.1    Keane, R.W.2    Marcillo, A.E.3
  • 116
    • 0036570042 scopus 로고    scopus 로고
    • Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion
    • Pan J.Z., Ni L., Sodhi A., et al. Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion. J Neurosci Res 2002, 68:315-322.
    • (2002) J Neurosci Res , vol.68 , pp. 315-322
    • Pan, J.Z.1    Ni, L.2    Sodhi, A.3
  • 117
    • 33847093475 scopus 로고    scopus 로고
    • Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
    • Park S.W., Yi J.H., Miranpuri G., et al. Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. J Pharmacol Exp Ther 2007, 320:1002-1012.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1002-1012
    • Park, S.W.1    Yi, J.H.2    Miranpuri, G.3
  • 118
    • 0242609183 scopus 로고    scopus 로고
    • Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury
    • Pearse D.D., Chatzipanteli K., Marcillo A.E., et al. Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury. J Neuropathol Exp Neurol 2003, 62:1096-1107.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 1096-1107
    • Pearse, D.D.1    Chatzipanteli, K.2    Marcillo, A.E.3
  • 119
    • 31444445868 scopus 로고    scopus 로고
    • Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms
    • Pereira M.P., Hurtado O., Cardenas A., et al. Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. J Cereb Blood Flow Metab 2006, 26:218-229.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 218-229
    • Pereira, M.P.1    Hurtado, O.2    Cardenas, A.3
  • 120
    • 16844365105 scopus 로고    scopus 로고
    • Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration
    • Perrin F.E., Lacroix S., Aviles-Trigueros M., et al. Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain 2005, 128:854-866.
    • (2005) Brain , vol.128 , pp. 854-866
    • Perrin, F.E.1    Lacroix, S.2    Aviles-Trigueros, M.3
  • 121
    • 33845568271 scopus 로고    scopus 로고
    • Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved
    • Pineau I., Lacroix S. Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved. J Comp Neurol 2007, 500:267-285.
    • (2007) J Comp Neurol , vol.500 , pp. 267-285
    • Pineau, I.1    Lacroix, S.2
  • 122
    • 0035126792 scopus 로고    scopus 로고
    • Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat
    • Plunkett J.A., Yu C.G., Easton J.M., et al. Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat. Exp Neurol 2001, 168:144-154.
    • (2001) Exp Neurol , vol.168 , pp. 144-154
    • Plunkett, J.A.1    Yu, C.G.2    Easton, J.M.3
  • 123
    • 43949114888 scopus 로고    scopus 로고
    • Can the immune system be harnessed to repair the CNS?
    • Popovich P.G., Longbrake E.E. Can the immune system be harnessed to repair the CNS?. Nat Rev Neurosci 2008, 9:481-493.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 481-493
    • Popovich, P.G.1    Longbrake, E.E.2
  • 124
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich P.G., Guan Z., Wei P., et al. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 1999, 158:351-365.
    • (1999) Exp Neurol , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3
  • 125
    • 0033775139 scopus 로고    scopus 로고
    • TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease
    • Probert L., Eugster H.P., Akassoglou K., et al. TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain 2000, 123:2005-2019.
    • (2000) Brain , vol.123 , pp. 2005-2019
    • Probert, L.1    Eugster, H.P.2    Akassoglou, K.3
  • 126
    • 0031418288 scopus 로고    scopus 로고
    • The astroglial response to Wallerian degeneration after spinal cord injury in humans
    • Puckett W.R., Hiester E.D., Norenberg M.D., et al. The astroglial response to Wallerian degeneration after spinal cord injury in humans. Exp Neurol 1997, 148:424-432.
    • (1997) Exp Neurol , vol.148 , pp. 424-432
    • Puckett, W.R.1    Hiester, E.D.2    Norenberg, M.D.3
  • 127
    • 33748802258 scopus 로고    scopus 로고
    • Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma
    • Qiao F., Atkinson C., Song H., et al. Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. Am J Pathol 2006, 169:1039-1047.
    • (2006) Am J Pathol , vol.169 , pp. 1039-1047
    • Qiao, F.1    Atkinson, C.2    Song, H.3
  • 128
    • 0025726977 scopus 로고
    • Proteins of the complement system and acute phase reactants in sera of patients with spinal cord injury
    • Rebhun J., Madorsky J.G., Glovsky M.M. Proteins of the complement system and acute phase reactants in sera of patients with spinal cord injury. Ann Allergy 1991, 66:335-338.
    • (1991) Ann Allergy , vol.66 , pp. 335-338
    • Rebhun, J.1    Madorsky, J.G.2    Glovsky, M.M.3
  • 129
    • 0029865092 scopus 로고    scopus 로고
    • Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat
    • Relton J.K., Martin D., Thompson R.C., et al. Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Exp Neurol 1996, 138:206-213.
    • (1996) Exp Neurol , vol.138 , pp. 206-213
    • Relton, J.K.1    Martin, D.2    Thompson, R.C.3
  • 130
    • 0031775322 scopus 로고    scopus 로고
    • Role of cyclooxygenase 2 in acute spinal cord injury
    • Resnick D.K., Graham S.H., Dixon C.E., et al. Role of cyclooxygenase 2 in acute spinal cord injury. J Neurotrauma 1998, 15:1005-1013.
    • (1998) J Neurotrauma , vol.15 , pp. 1005-1013
    • Resnick, D.K.1    Graham, S.H.2    Dixon, C.E.3
  • 131
    • 34247146400 scopus 로고    scopus 로고
    • Characterization of the early neuroinflammation after spinal cord injury in mice
    • Rice T., Larsen J., Rivest S., et al. Characterization of the early neuroinflammation after spinal cord injury in mice. J Neuropathol Exp Neurol 2007, 66:184-195.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 184-195
    • Rice, T.1    Larsen, J.2    Rivest, S.3
  • 132
    • 0029929404 scopus 로고    scopus 로고
    • Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells
    • Saada A., Reichert F., Rotshenker S. Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells. J Cell Biol 1996, 133:159-167.
    • (1996) J Cell Biol , vol.133 , pp. 159-167
    • Saada, A.1    Reichert, F.2    Rotshenker, S.3
  • 133
    • 0031960227 scopus 로고    scopus 로고
    • Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis
    • Sahrbacher U.C., Lechner F., Eugster H.P., et al. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis. Eur J Immunol 1998, 28:1332-1338.
    • (1998) Eur J Immunol , vol.28 , pp. 1332-1338
    • Sahrbacher, U.C.1    Lechner, F.2    Eugster, H.P.3
  • 134
    • 4644335622 scopus 로고    scopus 로고
    • Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury
    • Schwab J.M., Conrad S., Elbert T., et al. Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury. Glia 2004, 47:377-386.
    • (2004) Glia , vol.47 , pp. 377-386
    • Schwab, J.M.1    Conrad, S.2    Elbert, T.3
  • 135
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin E1 and protectin D1 activate inflammation-resolution programmes
    • Schwab J.M., Chiang N., Arita M., et al. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 2007, 447:869-874.
    • (2007) Nature , vol.447 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3
  • 136
    • 33646693142 scopus 로고    scopus 로고
    • Immune-based therapy for spinal cord repair: autologous macrophages and beyond
    • Schwartz M., Yoles E. Immune-based therapy for spinal cord repair: autologous macrophages and beyond. J Neurotrauma 2006, 23:360-370.
    • (2006) J Neurotrauma , vol.23 , pp. 360-370
    • Schwartz, M.1    Yoles, E.2
  • 137
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz M., Moalem G., Leibowitz-Amit R., et al. Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci 1999, 22:295-299.
    • (1999) Trends Neurosci , vol.22 , pp. 295-299
    • Schwartz, M.1    Moalem, G.2    Leibowitz-Amit, R.3
  • 138
    • 41749090254 scopus 로고    scopus 로고
    • Anti-inflammatory and proresolving lipid mediators
    • Serhan C.N., Yacoubian S., Yang R. Anti-inflammatory and proresolving lipid mediators. Annu Rev Pathol 2008, 3:279-312.
    • (2008) Annu Rev Pathol , vol.3 , pp. 279-312
    • Serhan, C.N.1    Yacoubian, S.2    Yang, R.3
  • 139
    • 0032728075 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice
    • Sinz E.H., Kochanek P.M., Dixon C.E., et al. Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice. J Clin Invest 1999, 104:647-656.
    • (1999) J Clin Invest , vol.104 , pp. 647-656
    • Sinz, E.H.1    Kochanek, P.M.2    Dixon, C.E.3
  • 140
    • 0032790541 scopus 로고    scopus 로고
    • Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
    • Springer J.E., Azbill R.D., Knapp P.E. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 1999, 5:943-946.
    • (1999) Nat Med , vol.5 , pp. 943-946
    • Springer, J.E.1    Azbill, R.D.2    Knapp, P.E.3
  • 141
    • 0037665153 scopus 로고    scopus 로고
    • Rats and mice exhibit distinct inflammatory reactions after spinal cord injury
    • Sroga J.M., Jones T.B., Kigerl K.A., et al. Rats and mice exhibit distinct inflammatory reactions after spinal cord injury. J Comp Neurol 2003, 462:223-240.
    • (2003) J Comp Neurol , vol.462 , pp. 223-240
    • Sroga, J.M.1    Jones, T.B.2    Kigerl, K.A.3
  • 142
    • 48249146633 scopus 로고    scopus 로고
    • Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry
    • Stirling D.P., Yong V.W. Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry. J Neurosci Res 2008, 86:1944-1958.
    • (2008) J Neurosci Res , vol.86 , pp. 1944-1958
    • Stirling, D.P.1    Yong, V.W.2
  • 143
    • 58849083367 scopus 로고    scopus 로고
    • Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome
    • Stirling D.P., Liu S., Kubes P., et al. Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci 2009, 29:753-764.
    • (2009) J Neurosci , vol.29 , pp. 753-764
    • Stirling, D.P.1    Liu, S.2    Kubes, P.3
  • 144
    • 0024366858 scopus 로고
    • Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression
    • Stoll G., Trapp B.D., Griffin J.W. Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression. J Neurosci 1989, 9:2327-2335.
    • (1989) J Neurosci , vol.9 , pp. 2327-2335
    • Stoll, G.1    Trapp, B.D.2    Griffin, J.W.3
  • 145
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: reversible adaptation to changing microenvironments
    • Stout R.D., Suttles J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J Leukoc Biol 2004, 76:509-513.
    • (2004) J Leukoc Biol , vol.76 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 146
    • 0036260491 scopus 로고    scopus 로고
    • Methylprednisolone and interleukin-10 reduce gray matter damage in the contused Fischer rat thoracic spinal cord but do not improve functional outcome
    • Takami T., Oudega M., Bethea J.R., et al. Methylprednisolone and interleukin-10 reduce gray matter damage in the contused Fischer rat thoracic spinal cord but do not improve functional outcome. J Neurotrauma 2002, 19:653-666.
    • (2002) J Neurotrauma , vol.19 , pp. 653-666
    • Takami, T.1    Oudega, M.2    Bethea, J.R.3
  • 147
    • 0030845563 scopus 로고    scopus 로고
    • Role of neutrophils in spinal cord injury in the rat
    • Taoka Y., Okajima K., Uchiba M., et al. Role of neutrophils in spinal cord injury in the rat. Neuroscience 1997, 79:1177-1182.
    • (1997) Neuroscience , vol.79 , pp. 1177-1182
    • Taoka, Y.1    Okajima, K.2    Uchiba, M.3
  • 148
    • 0037481943 scopus 로고    scopus 로고
    • Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice
    • Wells J.E., Hurlbert R.J., Fehlings M.G., et al. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain 2003, 126:1628-1637.
    • (2003) Brain , vol.126 , pp. 1628-1637
    • Wells, J.E.1    Hurlbert, R.J.2    Fehlings, M.G.3
  • 149
    • 63849150247 scopus 로고    scopus 로고
    • Endothelial signaling in paracellular and transcellular leukocyte transmigration
    • Wittchen E.S. Endothelial signaling in paracellular and transcellular leukocyte transmigration. Front Biosci 2009, 14:2522-2545.
    • (2009) Front Biosci , vol.14 , pp. 2522-2545
    • Wittchen, E.S.1
  • 150
    • 0021917038 scopus 로고
    • Spinal cord contusion in the rat: production of graded, reproducible, injury groups
    • Wrathall J.R., Pettegrew R.K., Harvey F. Spinal cord contusion in the rat: production of graded, reproducible, injury groups. Exp Neurol 1985, 88:108-122.
    • (1985) Exp Neurol , vol.88 , pp. 108-122
    • Wrathall, J.R.1    Pettegrew, R.K.2    Harvey, F.3
  • 151
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu D.C., Jackson-Lewis V., Vila M., et al. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 2002, 22:1763-1771.
    • (2002) J Neurosci , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3
  • 152
    • 59749091242 scopus 로고    scopus 로고
    • Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury
    • Xiong Y., Hall E.D. Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury. Exp Neurol 2009, 216:105-114.
    • (2009) Exp Neurol , vol.216 , pp. 105-114
    • Xiong, Y.1    Hall, E.D.2
  • 153
    • 33846196606 scopus 로고    scopus 로고
    • Role of peroxynitrite in secondary oxidative damage after spinal cord injury
    • Xiong Y., Rabchevsky A.G., Hall E.D. Role of peroxynitrite in secondary oxidative damage after spinal cord injury. J Neurochem 2007, 100:639-649.
    • (2007) J Neurochem , vol.100 , pp. 639-649
    • Xiong, Y.1    Rabchevsky, A.G.2    Hall, E.D.3
  • 154
    • 0034996414 scopus 로고    scopus 로고
    • INOS and nitrotyrosine expression after spinal cord injury
    • Xu J., Kim G.M., Chen S., et al. iNOS and nitrotyrosine expression after spinal cord injury. J Neurotrauma 2001, 18:523-532.
    • (2001) J Neurotrauma , vol.18 , pp. 523-532
    • Xu, J.1    Kim, G.M.2    Chen, S.3
  • 155
    • 2342596444 scopus 로고    scopus 로고
    • Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury
    • Yang L., Blumbergs P.C., Jones N.R., et al. Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury. Spine 2004, 29:966-971.
    • (2004) Spine , vol.29 , pp. 966-971
    • Yang, L.1    Blumbergs, P.C.2    Jones, N.R.3
  • 156
    • 17844406364 scopus 로고    scopus 로고
    • Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat
    • Yang L., Jones N.R., Blumbergs P.C., et al. Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat. J Clin Neurosci 2005, 12:276-284.
    • (2005) J Clin Neurosci , vol.12 , pp. 276-284
    • Yang, L.1    Jones, N.R.2    Blumbergs, P.C.3
  • 157
    • 0037444630 scopus 로고    scopus 로고
    • Macrophage-derived factors stimulate optic nerve regeneration
    • Yin Y., Cui Q., Li Y., et al. Macrophage-derived factors stimulate optic nerve regeneration. J Neurosci 2003, 23:2284-2293.
    • (2003) J Neurosci , vol.23 , pp. 2284-2293
    • Yin, Y.1    Cui, Q.2    Li, Y.3
  • 158
    • 33745712928 scopus 로고    scopus 로고
    • Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
    • Yin Y., Henzl M.T., Lorber B., et al. Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci 2006, 9:843-852.
    • (2006) Nat Neurosci , vol.9 , pp. 843-852
    • Yin, Y.1    Henzl, M.T.2    Lorber, B.3
  • 159
    • 34547915244 scopus 로고    scopus 로고
    • Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial
    • Yoon S.H., Shim Y.S., Park Y.H., et al. Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial. Stem Cells 2007, 25:2066-2073.
    • (2007) Stem Cells , vol.25 , pp. 2066-2073
    • Yoon, S.H.1    Shim, Y.S.2    Park, Y.H.3
  • 160
    • 0036454346 scopus 로고    scopus 로고
    • Spinal cord contusion models
    • Young W. Spinal cord contusion models. Prog Brain Res 2002, 137:231-255.
    • (2002) Prog Brain Res , vol.137 , pp. 231-255
    • Young, W.1
  • 161
    • 34249039892 scopus 로고    scopus 로고
    • The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study
    • Zabad R.K., Metz L.M., Todoruk T.R., et al. The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study. Mult Scler 2007, 13:517-526.
    • (2007) Mult Scler , vol.13 , pp. 517-526
    • Zabad, R.K.1    Metz, L.M.2    Todoruk, T.R.3
  • 162
    • 0029670958 scopus 로고    scopus 로고
    • Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion
    • Zhang F., Casey R.M., Ross M.E., et al. Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke 1996, 27:317-323.
    • (1996) Stroke , vol.27 , pp. 317-323
    • Zhang, F.1    Casey, R.M.2    Ross, M.E.3
  • 163
    • 45149091084 scopus 로고    scopus 로고
    • Pilot study of minocycline in relapsing-remitting multiple sclerosis
    • Zhang Y., Metz L.M., Yong V.W., et al. Pilot study of minocycline in relapsing-remitting multiple sclerosis. Can J Neurol Sci 2008, 35:185-191.
    • (2008) Can J Neurol Sci , vol.35 , pp. 185-191
    • Zhang, Y.1    Metz, L.M.2    Yong, V.W.3


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