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Volumn 153, Issue 3, 1998, Pages 801-813

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; LIGAND; MYELIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0031659763     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65622-2     Document Type: Article
Times cited : (288)

References (70)
  • 2
    • 0030056639 scopus 로고    scopus 로고
    • Mechanisms of immune injury in multiple sclerosis
    • Brosnan CF, Raine CS: Mechanisms of immune injury in multiple sclerosis. Brain Pathol 1996, 6:243-257
    • (1996) Brain Pathol , vol.6 , pp. 243-257
    • Brosnan, C.F.1    Raine, C.S.2
  • 3
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis
    • Lucchinetti CF, Bruck W, Rodriguez M, Lassmann H: Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis. Brain Pathol 1996, 6:259-274
    • (1996) Brain Pathol , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Bruck, W.2    Rodriguez, M.3    Lassmann, H.4
  • 4
    • 0029960673 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain
    • Dowling P, Shang G, Raval S, Menonna J, Cook S, Husar W: Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J Exp Med 1996, 184:1513-1518
    • (1996) J Exp Med , vol.184 , pp. 1513-1518
    • Dowling, P.1    Shang, G.2    Raval, S.3    Menonna, J.4    Cook, S.5    Husar, W.6
  • 5
    • 0029410743 scopus 로고
    • Interferon-γ induced oligodendrocytes cell death: Implications for the pathogenesis of multiple sclerosis
    • Vartanian T, Li Y, Zhao M, Stefansson K: Interferon-γ induced oligodendrocytes cell death: implications for the pathogenesis of multiple sclerosis. Mol Med 1995, 1:732-743
    • (1995) Mol Med , vol.1 , pp. 732-743
    • Vartanian, T.1    Li, Y.2    Zhao, M.3    Stefansson, K.4
  • 7
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil SS, Steinman L: The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol 1990, 8:579-621
    • (1990) Annu Rev Immunol , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 10
    • 0028872064 scopus 로고
    • Two models of multiple sclerosis experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection; a pathological and immunological comparison
    • Dal Canto MC, Melvold RW, Kim BS, Miller SD: Two models of multiple sclerosis experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection; a pathological and immunological comparison. Microsc Res Tech 1995, 32:215-229
    • (1995) Microsc Res Tech , vol.32 , pp. 215-229
    • Dal Canto, M.C.1    Melvold, R.W.2    Kim, B.S.3    Miller, S.D.4
  • 11
    • 0030589225 scopus 로고    scopus 로고
    • The balance between persistent virus infection and immune cells determines demyelination
    • Rodriguez M, Pavelko KD, Njjenga MK, Logan WC, Wettstein PJ: The balance between persistent virus infection and immune cells determines demyelination. J Immunol 1996, 157:5699-5709
    • (1996) J Immunol , vol.157 , pp. 5699-5709
    • Rodriguez, M.1    Pavelko, K.D.2    Njjenga, M.K.3    Logan, W.C.4    Wettstein, P.J.5
  • 12
    • 84993913357 scopus 로고
    • Multiple sclerosis: TNF revisited, with promise
    • Raine CS: Multiple sclerosis: TNF revisited, with promise. Nat Med 1995, 1:211-214
    • (1995) Nat Med , vol.1 , pp. 211-214
    • Raine, C.S.1
  • 13
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE: Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989, 170:607-612
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 14
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj KW, Raine CS, Cannella B, Brosnan CF: Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991, 87:949-954
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.W.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 15
    • 0030738366 scopus 로고    scopus 로고
    • Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
    • Bonetti B, Raine CS: Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann Neurol 1997, 42:74-84
    • (1997) Ann Neurol , vol.42 , pp. 74-84
    • Bonetti, B.1    Raine, C.S.2
  • 16
    • 0025773147 scopus 로고
    • Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis
    • Sharief MK, Hentges R: Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis. N Engl J Med 1991, 325:467-472
    • (1991) N Engl J Med , vol.325 , pp. 467-472
    • Sharief, M.K.1    Hentges, R.2
  • 17
    • 0025092159 scopus 로고
    • Proliferation of astrocytes in vitro in response to cytokines: A primary role for tumor necrosis factor
    • Selmaj KW, Farooq M, Norton WT, Raine CS, Brosnan CF: Proliferation of astrocytes in vitro in response to cytokines: a primary role for tumor necrosis factor. J Immunol 1990, 144:129-135
    • (1990) J Immunol , vol.144 , pp. 129-135
    • Selmaj, K.W.1    Farooq, M.2    Norton, W.T.3    Raine, C.S.4    Brosnan, C.F.5
  • 18
    • 0025813019 scopus 로고
    • Effects of interleukin-1 and tumor necrosis factor-α on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro
    • Merrill J: Effects of interleukin-1 and tumor necrosis factor-α on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro. Dev Neurosci 1991, 13:130-137
    • (1991) Dev Neurosci , vol.13 , pp. 130-137
    • Merrill, J.1
  • 19
    • 0030054637 scopus 로고    scopus 로고
    • Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1
    • Karmann K, Min W, Fanslow WC, Pober JS: Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. J Exp Med 1996, 184:173-182
    • (1996) J Exp Med , vol.184 , pp. 173-182
    • Karmann, K.1    Min, W.2    Fanslow, W.C.3    Pober, J.S.4
  • 20
    • 0030240326 scopus 로고    scopus 로고
    • The central nervous system as an immunocompetent organ: Role of glial cells in antigen presentation
    • Shrikant P, Benveniste EN: The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation. J Immunol 1996, 157:1819-1822
    • (1996) J Immunol , vol.157 , pp. 1819-1822
    • Shrikant, P.1    Benveniste, E.N.2
  • 21
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN: Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 1996, 19:331-338
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 22
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS: Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 1988, 23:339-346
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 23
    • 0025827448 scopus 로고
    • Cytokine cytotoxicity against oligodendrocytes: Apoptosis induced by lymphotoxin
    • Selmaj K, Raine CS, Farooq M, Norton WT, Brosnan CF: Cytokine cytotoxicity against oligodendrocytes: apoptosis induced by lymphotoxin. J Immunol 1991, 147:1522-1529
    • (1991) J Immunol , vol.147 , pp. 1522-1529
    • Selmaj, K.1    Raine, C.S.2    Farooq, M.3    Norton, W.T.4    Brosnan, C.F.5
  • 24
    • 0030942747 scopus 로고    scopus 로고
    • ICE/CED-3 family executes oligodendrocyte apoptosis by tumor necrosis factor
    • Hisahara S, Shoji S, Okano H, Miura M: ICE/CED-3 family executes oligodendrocyte apoptosis by tumor necrosis factor. J Neurochem 1997, 69:10-20
    • (1997) J Neurochem , vol.69 , pp. 10-20
    • Hisahara, S.1    Shoji, S.2    Okano, H.3    Miura, M.4
  • 26
    • 0028066844 scopus 로고
    • Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins
    • Baker D, Butler D, Scallon BJ, O'Neill JK, Turk JL, Feldmann M: Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur J Immunol 1994, 24:2040-2048
    • (1994) Eur J Immunol , vol.24 , pp. 2040-2048
    • Baker, D.1    Butler, D.2    Scallon, B.J.3    O'Neill, J.K.4    Turk, J.L.5    Feldmann, M.6
  • 27
    • 0028855346 scopus 로고
    • Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I
    • Selmaj K, Papierz W, Glabinski A, Kohno T: Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I. J Neuroimmunol 1995, 56:135-141
    • (1995) J Neuroimmunol , vol.56 , pp. 135-141
    • Selmaj, K.1    Papierz, W.2    Glabinski, A.3    Kohno, T.4
  • 29
    • 0030918326 scopus 로고    scopus 로고
    • Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis
    • Frei K, Eugster H-P, Bopst M, Constantinescu CS, Lavi E, Fontana A: Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis. J Exp Med 1997, 185:2177-2182
    • (1997) J Exp Med , vol.185 , pp. 2177-2182
    • Frei, K.1    Eugster, H.-P.2    Bopst, M.3    Constantinescu, C.S.4    Lavi, E.5    Fontana, A.6
  • 30
    • 0030856118 scopus 로고    scopus 로고
    • A critical role for lymphotoxin in experimental allergic encephalomyelitis
    • Suen WE, Bergman CM, Hjelmstrom P, Ruddle NH: A critical role for lymphotoxin in experimental allergic encephalomyelitis. J Exp Med 1997, 186:1233-1240
    • (1997) J Exp Med , vol.186 , pp. 1233-1240
    • Suen, W.E.1    Bergman, C.M.2    Hjelmstrom, P.3    Ruddle, N.H.4
  • 31
    • 0038917435 scopus 로고    scopus 로고
    • Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
    • Korner H, Rimington DS, Strickland DH, Lemckert FA, Pollard JD, Sedgwick JD: Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J Exp Med 1997, 186:1585-1590
    • (1997) J Exp Med , vol.186 , pp. 1585-1590
    • Korner, H.1    Rimington, D.S.2    Strickland, D.H.3    Lemckert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 33
    • 0030905895 scopus 로고    scopus 로고
    • Some misconceptions about understanding autoimmunity through experiments with knockouts
    • Steinman L: Some misconceptions about understanding autoimmunity through experiments with knockouts. J Exp Med 1997, 185:2039-2041
    • (1997) J Exp Med , vol.185 , pp. 2039-2041
    • Steinman, L.1
  • 35
    • 0028864801 scopus 로고
    • Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor α
    • Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G, Kollias G: Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor α. Proc Natl Acad Sci USA 1995, 92:11294-11298
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11294-11298
    • Probert, L.1    Akassoglou, K.2    Pasparakis, M.3    Kontogeorgos, G.4    Kollias, G.5
  • 36
    • 0030639621 scopus 로고    scopus 로고
    • Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice
    • Akassoglou K, Probert L, Kontogeorgos G, Kollias G: Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. J Immunol 1997, 158:438-445
    • (1997) J Immunol , vol.158 , pp. 438-445
    • Akassoglou, K.1    Probert, L.2    Kontogeorgos, G.3    Kollias, G.4
  • 37
    • 0027327619 scopus 로고
    • Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
    • Rothe J, Lesslauer W, Lotscher H, Lang Y, Koebel P, Kontgen F, Althage A, Zinkernagel R, Steinmetz M, Bluethmann H: Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 1993, 364:798-802
    • (1993) Nature , vol.364 , pp. 798-802
    • Rothe, J.1    Lesslauer, W.2    Lotscher, H.3    Lang, Y.4    Koebel, P.5    Kontgen, F.6    Althage, A.7    Zinkernagel, R.8    Steinmetz, M.9    Bluethmann, H.10
  • 39
    • 0029989339 scopus 로고    scopus 로고
    • Immune and inflammatory responses in TNF α-deficient mice: A critical requirement for TNF α in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
    • Pasparakis M, Alexopoulou L, Episkopou V, Kollias G: Immune and inflammatory responses in TNF α-deficient mice: a critical requirement for TNF α in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J Exp Med 1996, 184:1397-1411
    • (1996) J Exp Med , vol.184 , pp. 1397-1411
    • Pasparakis, M.1    Alexopoulou, L.2    Episkopou, V.3    Kollias, G.4
  • 41
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
    • Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV, Lassmann H: Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 1994, 71:219-225
    • (1994) Lab Invest , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3    Breitschopf, H.4    Hartung, H.P.5    Toyka, K.V.6    Lassmann, H.7
  • 42
    • 0026468291 scopus 로고
    • In situ hybridization with digoxigenin-labeled probes: Sensitive and reliable detection method applied to myelinating rat brain
    • Breitschopf H, Suchanek G, Gould RM, Coleman DR, Lassmann H: In situ hybridization with digoxigenin-labeled probes: sensitive and reliable detection method applied to myelinating rat brain. Acta Neuropathol 1992, 84:581-587
    • (1992) Acta Neuropathol , vol.84 , pp. 581-587
    • Breitschopf, H.1    Suchanek, G.2    Gould, R.M.3    Coleman, D.R.4    Lassmann, H.5
  • 43
    • 0026008986 scopus 로고
    • Glial cell differentiation in neuron-free and neuron-rich regions. I. Selective appearance of S-100 protein in radial glial cells of the hippocampal fimbria in human fetuses
    • Berl
    • Stagaard Janas M, Nowakowski RS, Terkelsen OB, Mollgard K: Glial cell differentiation in neuron-free and neuron-rich regions. I. Selective appearance of S-100 protein in radial glial cells of the hippocampal fimbria in human fetuses. Anat Embryol (Berl) 1991, 184:549-558
    • (1991) Anat Embryol , vol.184 , pp. 549-558
    • Stagaard Janas, M.1    Nowakowski, R.S.2    Terkelsen, O.B.3    Mollgard, K.4
  • 44
    • 0024418358 scopus 로고
    • Vacuolar myelopathy with multinucleated giant cells in the aquired immune deficiency syndrome (AIDS): Light and electron microscopic distribution of human immunodeficiency virus (HIV) antigens
    • Maier H, Budka H, Lassmann H, Pohl P: Vacuolar myelopathy with multinucleated giant cells in the aquired immune deficiency syndrome (AIDS): light and electron microscopic distribution of human immunodeficiency virus (HIV) antigens. Acta Neuropathol 1989, 78: 497-503
    • (1989) Acta Neuropathol , vol.78 , pp. 497-503
    • Maier, H.1    Budka, H.2    Lassmann, H.3    Pohl, P.4
  • 45
  • 46
  • 49
    • 0025787089 scopus 로고
    • Multiple sclerosis: A pivotal role for the T cell in lesion development
    • Raine CS: Multiple sclerosis: a pivotal role for the T cell in lesion development. Neuropathol Appl Neurobiol 1991, 17:265-274
    • (1991) Neuropathol Appl Neurobiol , vol.17 , pp. 265-274
    • Raine, C.S.1
  • 50
    • 0025289805 scopus 로고
    • Persistent anti-myelin basic protein IgG antibody response in multiple sclerosis cerebrospinal fluid
    • Link H, Baig S, Olsson O, Yu-Ping J, Hojeberg B, Olsson T: Persistent anti-myelin basic protein IgG antibody response in multiple sclerosis cerebrospinal fluid. J Neuroimmunol 1990, 28:237-248
    • (1990) J Neuroimmunol , vol.28 , pp. 237-248
    • Link, H.1    Baig, S.2    Olsson, O.3    Yu-Ping, J.4    Hojeberg, B.5    Olsson, T.6
  • 52
    • 0031302405 scopus 로고    scopus 로고
    • Cell death during autoimmune demyelination: Effector but not target cells are eliminated by apoptosis
    • Bonetti B, Pohl J, Gao Y-L, Raine CS: Cell death during autoimmune demyelination: effector but not target cells are eliminated by apoptosis. J Immunol 1997, 159:5733-5741
    • (1997) J Immunol , vol.159 , pp. 5733-5741
    • Bonetti, B.1    Pohl, J.2    Gao, Y.-L.3    Raine, C.S.4
  • 53
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli P: The pathophysiology of tumor necrosis factors. Annu Rev Immunol 1992, 10:411-452
    • (1992) Annu Rev Immunol , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 54
    • 0029845006 scopus 로고    scopus 로고
    • Mechanisms of cytokine-mediated localized immunoprotection
    • Sarvetnick N: Mechanisms of cytokine-mediated localized immunoprotection. J Exp Med 1996, 184:1597-1600
    • (1996) J Exp Med , vol.184 , pp. 1597-1600
    • Sarvetnick, N.1
  • 58
    • 0029817787 scopus 로고    scopus 로고
    • Heightened expression of tumor necrosis factor α, interleukin 1α, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice
    • Kordek R, Nerurkar VR, Liberski PP, Isaacson S, Yanagihara R, Gajdusek DC: Heightened expression of tumor necrosis factor α, interleukin 1α, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice. Proc Natl Acad Sci USA 1996, 93:9754-9758
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9754-9758
    • Kordek, R.1    Nerurkar, V.R.2    Liberski, P.P.3    Isaacson, S.4    Yanagihara, R.5    Gajdusek, D.C.6
  • 59
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu Z-G, Hsu H, Goeddel DV, Karin M: Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 1996, 87:565-576
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.-G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 60
  • 61
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α-induced cell death
    • Beg AA, Baltimore D: An essential role for NF-κB in preventing TNF-α-induced cell death. Science 1996, 274:782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 63
    • 0030996264 scopus 로고    scopus 로고
    • Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia
    • Dopp JM, Mackenzie-Graham A, Otero GC, Merrill JE: Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia. J Neuroimmunol 1997, 75:104-112
    • (1997) J Neuroimmunol , vol.75 , pp. 104-112
    • Dopp, J.M.1    Mackenzie-Graham, A.2    Otero, G.C.3    Merrill, J.E.4
  • 64
    • 0028882460 scopus 로고
    • Differential oligodendroglial expression of the tumor necrosis factor receptors in vivo and in vitro
    • Tchelingerian JL, Monge M, Le Saux F, Zalc B, Jacque C: Differential oligodendroglial expression of the tumor necrosis factor receptors in vivo and in vitro. J Neurochem 1995, 65:2377-2380
    • (1995) J Neurochem , vol.65 , pp. 2377-2380
    • Tchelingerian, J.L.1    Monge, M.2    Le Saux, F.3    Zalc, B.4    Jacque, C.5
  • 65
    • 0027082393 scopus 로고
    • Interactions between oligodendrocytes and microglia: A major role for complement and tumour necrosis factor in oligodendrocyte adherence and killing
    • Zajicek JP, Wing M, Scolding NJ, Compston DAS: Interactions between oligodendrocytes and microglia: a major role for complement and tumour necrosis factor in oligodendrocyte adherence and killing. Brain 1992, 115:1611-1631
    • (1992) Brain , vol.115 , pp. 1611-1631
    • Zajicek, J.P.1    Wing, M.2    Scolding, N.J.3    Compston, D.A.S.4
  • 66
    • 0025850757 scopus 로고
    • The longstanding MS lesion: A quantitative MRI and electron microscopic study
    • Barnes D, Munro PM, Youl BD, Prineas JW, McDonald WI: The longstanding MS lesion: a quantitative MRI and electron microscopic study. Brain 1991, 114:1271-1280
    • (1991) Brain , vol.114 , pp. 1271-1280
    • Barnes, D.1    Munro, P.M.2    Youl, B.D.3    Prineas, J.W.4    McDonald, W.I.5
  • 67
    • 0028178798 scopus 로고
    • Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
    • Cheng B, Christakos S, Mattson MP: Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 1994, 12:139-153
    • (1994) Neuron , vol.12 , pp. 139-153
    • Cheng, B.1    Christakos, S.2    Mattson, M.P.3
  • 70
    • 0023108382 scopus 로고
    • Astrocytes induce blood-brain barrier properties in endothelial cells
    • Janzer RC, Raff MC: Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 1987, 325:253-257
    • (1987) Nature , vol.325 , pp. 253-257
    • Janzer, R.C.1    Raff, M.C.2


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