Traumatic spinal cord injury produced by controlled contusion in mouse

Journal of Neurotrauma

Volumn 17, Issue 4, 2000, Pages 299-319

  Jakeman, Lyn B ^a,b   Guan, Zhen ^a   Ping, Wei ^a   Ponnappan, Ravi ^a   Dzwonczyk, Roger ^a   Popovich, Phillip G ^a   Stokes, Bradford T ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b 302 Hamilton Hall ^*  (United States)

Author keywords

Behavioral outcome; Biomechanical feedback; Histopathology; Inflammation; Murine; Rapid compression; Recovery of function; Wound healing

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; CONVALESCENCE; ELECTROMAGNETIC FIELD; FEMALE; GENETIC ENGINEERING; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LOCOMOTION; MALE; MOUSE; MUTATION; NONHUMAN; SCAR FORMATION; SPINAL CORD INJURY;

EID: 0034076496     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2000.17.299     Document Type: Article

References (51)

1. ALLEN, A.R. (1911). Surgery of experimental lesion of spinal cord equivalent to crush injury or fracture dislocation of spinal column. A preliminary report. J.A.M.A. 57, 870-880.
2. ANDERSON, T.E., and STOKES, B.T. (1992). Experimental models for spinal cord injury research: physical and physiological considerations. J. Neurotrauma 9, Suppl. 1, S135-S142.
3. BALENTINE, J.D. (1978). Pathology of experimental spinal cord trauma. I. The necrotic lesion as a function of vascular injury. Lab. Invest. 39, 236-253.
4. BASSO, D.M., BEATTIE, M.S., and BRESNAHAN, J.C. (1995). A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12, 1-21.
5. BASSO, D.M., BEATTIE, M.S., and BRESNAHAN, J.C. (1996a). Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp. Neurol. 139, 244-256.
6. BASSO, D.M., BEATTIE, M.S., BRESNAHAN, J.C., et al. (1996b). MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. J. Neurotrauma 13, 343-359.
7. BEHRMANN, D.L., BRESNAHAN, J.C., BEATTIE, M.S., and SHAH, B.R. (1992). Spinal cord injury produced by consistent displacement of the cord in rats: behavioral and histologic analysis. J. Neurotrauma 9, 197-217.
8. BLIGHT, A.R. (1985). Computer simulation of action potentials and after potential in mammalian myelinated axons: the case for a lower resistance myelin sheath. Neuroscience 15, 13-31.
9. BLIGHT, A. (1988). Mechanical factors in experimental spinal cord injury. J. Am. Paraplegia Soc. 11, 26-34.
10. BLIGHT, A.R. (1996). An overview of spinal cord injury models, in: Neurotrauma. R.K. Narayan, J.E. Wilberger, and J.T. Povlishock (eds), McGraw Hill: New York, pps. 1367-1379.
11. BRESNAHAN, J.C., BEATTIE, M.S., TODD, F.D., III, and NOYES, D.H. (1987). A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device. Exp. Neurol. 95, 548-570.
12. BUNGE, R.P., PUCKETT, W.R., BECERRA, J.L., MARCILLO, A., and QUENCER, R.M. (1993). Observations on the pathology of human spinal cord injury: a review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination, in: Advances in Neurology. F.J. Seil (ed), Raven Press: New York, pps.75-89.
13. BUNGE, R.P., PUCKETT, W.R., and HIESTER, E.D. (1997). Observations on the pathology of several types of human spinal cord injury, with emphasis on the astrocyte response to penetrating injuries, in: Neuronal Regeneration, Reorganization, and Repair. F.J. Seil (ed), Lippincott-Raven Publishers: Philadelphia, pps. 305-315.
14. CARLSON, S.L., PARRISH, M.E., SPRINGER, J.E., DOTY, K., and DOSSETT, L. (1998). Acute inflammatory response in spinal cord following impact injury. Exp. Neurol. 151, 77-88.
15. DOHRMANN, G.J., and PANJABI, M.M. (1976). "Standardized" spinal cord trauma: biomechanical parameters and lesion volume. Surg. Neurol. 6, 263-267.
16. DUCKER, T.B., and HAMIT, H.F. (1969). Experimental treatments of acute spinal cord injury. J. Neurosurg. 30, 693-697.
17. DUCKER, T.B., KINDT, G.W., and KEMPE, L.G. (1971). Pathological findings in acute experimental spinal cord trauma. J. Neurosurg. 35, 700-708.
18. DUSART, I., and SCHWAB, M.E. (1993). Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur. J. Neurosci. 6, 712-724.
19. FORD, R.W. (1983). A reproducible spinal cord injury model in the cat. J. Neurosurg. 59, 268-275.
20. FREEMAN, L.W., and WRIGHT, T. (1953). Experimental observations of concussion and contusion of the spinal cord. Ann. Surg. 137, 433-443.
21. FUJIKI, M., ZHANG, Z., GUTH, L., and STEWARD, O. (1996). Genetic influences on cellular reactions to spinal cord injury: activation of macrophages/microglia and astrocytes is delayed in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J. Comp. Neurol. 371, 469-484.
22. GALE, K., KERASIDIS, H., and WRATHALL, J.R. (1985). Spinal cord contusion in the rat: behavioral analysis of functional neurologic impairment. Exp. Neurol. 88, 123-134.
23. GRIFFITHS, I.R. (1976). Spinal cord blood flow after acute experimental cord injury in dogs. J. Neurol. Sci. 27, 247-259.
24. HEBEL, R., and STROMBERG, I. (1986). Anatomy and Embryology of the Laboratory Rat. Biomed Verlag Worthsee: Worthsee, Germany.
25. HSU, S.M., RAINE, L., and FANGER, H. (1981). The use of antiavidin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics. Am. J. Clin. Pathol. 75, 816-821.
26. KAKULAS, B. (1996). A Quantitative Study of Tissue Elements in Human Spinal Cord Injuries (SCI). Annual Review, International Spinal Research Trust. J. Cavanagh, Ed. ISRT Research Division, Surrey, UK.
27. KOOZEKANANI, S.H., VISE, W.M., HASHEMI, R.M., and MCGHEE, R.B. (1976). Possible mechanism for observed pathophysiological variability in experimental spinal cord injury by the method of Allen. J. Neurosurg. 44, 429-434.
28. KRIKORIAN, J.G., GUTH, L., and DONATI, E.J. (1981). Origin of the connective tissue scar in the transected rat spinal cord. Exp. Neurol. 72, 698-707.
29. KUHN, P.L., and WRATHALL, J.R. (1998). A mouse model of graded contusive spinal cord injury. J. Neurotrauma 15, 125-140.
30. MA, M., WALTERS, P., BASSO, D.M., STOKES, B.T., and JAKEMAN, L.B. (1998). Time course of behavioral recovery after contusion injury in mouse. J. Neurotrauma 15, 882.
31. MA, M., WALTERS, P., WEI, P., BASSO, D.M., STOKES, B.T., and JAKEMAN, L.B. (1999). Mouse contusion injury: Behavioral and histological characterization. Society for Neuroscience Abstracts 25, 311.
32. NATHAN, C.F. (1987). Secretory products of macrophages. J. Clin. Invest. 79, 319-326.
33. NOYES, D.H. (1987a). Correlation between parameters of spinal cord impact and resultant injury. Exp. Neurol. 95, 535-547.
34. NOYES, D.H. (1987b). Electromechanical impactor for producing experimental spinal cord injury in animals. Med. Biol. Eng. Comp. 25, 335-340.
35. PANJABI, M.M. (1987). Experimental spinal cord trauma. A biomechanical viewpoint. Paraplegia 25, 217-220.
36. PANJABI, M.M., and WRATHALL, J.R. (1988). Biomechanical analysis of experimental spinal cord injury and functional loss. Spine 13, 1365-1370.
37. PENDER, M.P., STANLEY, G.P., YOONG, G., and NGUYEN, K.B. (1990). The neuropathology of chronic relapsing experimental allergic encephalomyelitis induced in the Lewis rat by inoculation with whole spinal cord and treatment with cyclosporin A. Acta Neuropathol. 80, 172-183.
38. POPOVICH, P.G., WEI, P., and STOKES, B.T. (1997). The cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J. Comp. Neurol. 377, 443-464.
39. STEWARD, O., SCHAUWECKER, P.E., GUTH, L., et al. (1999). Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Exp. Neurol. 157, 19-42.
40. STOKES, B.T., and HORNER, P.J. (1996). Spinal cord injury modeling and functional outcome assessment, in: Neurotrauma. R.K. Narayan, J.E. Wilberger, and J.T. Povlishock (eds), McGraw Hill: New York, pps. 1395-1403.
41. STOKES, B.T., HORNER, P.J., and AKINO, M. (1995). Spinal cord injury modeling and functional assessment, in: Central Nervous System Trauma: Research Techniques. S.T. Ohnishi and T. Ohnishi (eds), CRC Press: New York, pps. 281-295.
42. STOKES, B.T., NOYES, D.H., and BEHRMANN, D.L. (1992). An electromechanical spinal injury device with dynamic sensitivity. J. Neurotrauma 9, 187-195.
43. TARLOV, I.M., and KLINGER, H. (1954). Spinal cord compression studies. III. Time limits for recovery after acute compression in dogs. Arch. Neurol. Psychiatry 71, 588-597.
44. THOMPSON, F.J., REIER, P.J., LUCAS, C.C., and PARMER, R. (1992). Altered patterns of reflex excitability subsequent to contusion injury of the rat spinal cord. J. Neurophysiol. 68, 1473-1486.
45. VERISH, H.T. (1979). A two cent bodian stain. J. Histotechnol. 2, 22-23.
46. WANG, X., MESSING, A., and DAVID, S. (1997). Axonal and nonneuronal cell responses to spinal cord injury in mice lacking glial fibrillary acidic protein. Exp. Neurol. 148, 568-576.
47. YEO, J.D., PAYNE, W., HINWOOD, B., and KIDMAN, A.D. (1975). The experimental contusion injury of the spinal cord in sheep. Paraplegia 12, 279-298.
48. YEO, J.D., HALES, J.R., STABBACK, S., BRADLEY, S., FAWCETT, A.A., and KEARNS, R. (1984). Effects of a contusion injury on spinal cord blood flow in the sheep. Spine 9, 676-680.
49. ZHANG, Z., and GUTH, L. (1997). Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration. Exp. Neurol. 147, 159-171.
50. ZHANG, Z., FUJIKI, M., GUTH, L, and STEWARD, O. (1996). Genetic influences on cellular reactions to spinal cord injury: a wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J. Comp. Neurol. 371, 485-495.
51. ZHANG, Z., KREBS, C.J., and GUTH, L. (1997). Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response. Exp. Neurol. 143, 141-152.