Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats

Brain, Behavior, and Immunity

Volumn 24, Issue 6, 2010, Pages 959-967

  Loram, Lisa C ^a   Harrison, Jacqueline A ^a   Chao, Lindsey ^a   Taylor, Frederick R ^a   Reddy, Anireddy ^a   Travis, Carissa L ^a   Giffard, Rona ^b   Al Abed, Yousef ^c   Tracey, Kevin ^c   Maier, Steven F ^a   Watkins, Linda R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Choline; Intrathecal; Pain; Rats; Tumor necrosis factor

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; BIOLOGICAL MARKER; BUNGAROTOXIN RECEPTOR; CD11B ANTIGEN; CHOLINE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; I KAPPA B; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NICOTINIC AGENT; TUMOR NECROSIS FACTOR ALPHA; 3-(2,4-DIMETHOXYBENZYLIDENE)ANABASEINE; BENZYLIDENE DERIVATIVE; CHRNA7 PROTEIN, RAT; COMPLEMENTARY DNA; CYTOKINE; NERVE PROTEIN; NICOTINIC RECEPTOR; PRIMER DNA; PYRIDINE DERIVATIVE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL TEST; GENE EXPRESSION; LUMBAR SPINAL CORD; MALE; MECHANICAL ALLODYNIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; VON FREY TEST; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; PAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; SPRAGUE DAWLEY RAT; STIMULATION;

ANIMALS; BENZYLIDENE COMPOUNDS; CYTOKINES; DNA PRIMERS; DNA, COMPLEMENTARY; HIV ENVELOPE PROTEIN GP120; INJECTIONS, SPINAL; INTERLEUKIN-1BETA; MALE; NERVE TISSUE PROTEINS; NICOTINIC AGONISTS; PAIN; PHYSICAL STIMULATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD; TUMOR NECROSIS FACTOR-ALPHA; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR;

EID: 77954215043     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.03.008     Document Type: Article

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