IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection

Brain, Behavior, and Immunity

Volumn 25, Issue 5, 2011, Pages 820-829

  Xin, Junping ^a,b   Wainwright, Derek A ^c   Mesnard, Nichole A ^a,b   Serpe, Craig J ^b   Sanders, Virginia M ^d   Jones, Kathryn J ^a,b  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b HINES VA HOSPITAL   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Axotomy; CD4+ T cell; Facial motoneuron; Interleukin 10; Neuroprotection; Survival

Indexed keywords

ALSACTIDE; CD4 ANTIGEN; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR ALPHA; INTERLEUKIN 10 RECEPTOR BETA; MESSENGER RNA; RAG2 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN STEM; CD4+ T LYMPHOCYTE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; FACIAL NERVE; FEMALE; GENE EXPRESSION; GLIA; IMMUNOFLUORESCENCE; IMMUNOMODULATION; LASER MICROBEAM MICRODISSECTION; MOTONEURON; MOUSE; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TH2 CELL; WILD TYPE;

ADOPTIVE TRANSFER; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FACIAL NERVE INJURIES; FEMALE; IMMUNITY, CELLULAR; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-10 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-10 RECEPTOR BETA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR NEURONS; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79957921767     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.08.004     Document Type: Article

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