Activation of murine microglial cell lines by lipopolysaccharide and interferon-γ causes NO-mediated decreases in mitochondrial and cellular function

European Journal of Neuroscience

Volumn 13, Issue 3, 2001, Pages 529-538

  Moss, David W ^a,b   Bates, Timothy E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

ATP; Glutathione; Murine; Neurodegeneration; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIUM LIPOPOLYSACCHARIDE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; CYTOKINE; GAMMA INTERFERON; GLUTATHIONE; LACTATE DEHYDROGENASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); TRYPAN BLUE; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEGENERATIVE DISEASE; ELECTRON TRANSPORT; ENZYME INDUCTION; MICROGLIA; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; MOUSE; NERVE CELL MEMBRANE; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTATHIONE; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGE INFLAMMATORY PROTEIN-1; MACROPHAGES; MICE; MICROGLIA; MITOCHONDRIA; NERVE DEGENERATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OMEGA-N-METHYLARGININE; OXIDATIVE STRESS;

EID: 0035135369     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2001.01418.x     Document Type: Article

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