-
1
-
-
61349152312
-
Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice
-
Abulafia D. P., de Rivero Vaccari J. P., Lozano J. D., Lotocki G., Keane R. W., and, Dietrich W. D., (2009) Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J. Cereb. Blood Flow Metab. 29, 534-544.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 534-544
-
-
Abulafia, D.P.1
De Rivero, V.J.P.2
Lozano, J.D.3
Lotocki, G.4
Keane, R.W.5
Dietrich, W.D.6
-
2
-
-
44649184557
-
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy
-
Ago T., Liu T., Zhai P., Chen W., Li H., Molkentin J. D., Vatner S. F., and, Sadoshima J., (2008) A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. Cell 133, 978-993.
-
(2008)
Cell
, vol.133
, pp. 978-993
-
-
Ago, T.1
Liu, T.2
Zhai, P.3
Chen, W.4
Li, H.5
Molkentin, J.D.6
Vatner, S.F.7
Sadoshima, J.8
-
4
-
-
23444441962
-
Interleukin-1 and neuronal injury
-
Allan S. M., Tyrrell P. J., and, Rothwell N. J., (2005) Interleukin-1 and neuronal injury. Nat. Rev. Immunol. 5, 629-640.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 629-640
-
-
Allan, S.M.1
Tyrrell, P.J.2
Rothwell, N.J.3
-
5
-
-
84858254017
-
PDGF receptor signaling in pericytes following ischemic brain injury
-
Arimura K., Ago T., Kamouchi M., Nakamura K., Ishitsuka K., Kuroda J., Sugimori H., Ooboshi H., Sasaki T., and, Kitazono T., (2012) PDGF receptor signaling in pericytes following ischemic brain injury. Curr. Neurovasc. Res. 9, 1-9.
-
(2012)
Curr. Neurovasc. Res.
, vol.9
, pp. 1-9
-
-
Arimura, K.1
Ago, T.2
Kamouchi, M.3
Nakamura, K.4
Ishitsuka, K.5
Kuroda, J.6
Sugimori, H.7
Ooboshi, H.8
Sasaki, T.9
Kitazono, T.10
-
6
-
-
74549178528
-
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
-
Arslan F., Smeets M. B., O'Neill L. A., et al,. (2010) Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody. Circulation 121, 80-90.
-
(2010)
Circulation
, vol.121
, pp. 80-90
-
-
Arslan, F.1
Smeets, M.B.2
O'Neill, L.A.3
-
7
-
-
0033638508
-
Role for matrix metalloproteinase 9 after cerebral ischemia: Effects of gene knockout and enzyme inhibition with BB-94
-
Asahi M., Asahi K., Jung J. C., del Zoppo G. J., Fini M. E., and, Lo E. H., (2000) Role for matrix metalloproteinase 9 after cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J. Cereb. Blood Flow Metab. 20, 1681-1689.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 1681-1689
-
-
Asahi, M.1
Asahi, K.2
Jung, J.C.3
Del Zoppo, G.J.4
Fini, M.E.5
Lo, E.H.6
-
8
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone F. C., and, Feuerstein G. Z., (1999) Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 19, 819-834.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
9
-
-
59349084695
-
Sensitization and tolerization to brain antigens in stroke
-
Becker K. J., (2009) Sensitization and tolerization to brain antigens in stroke. Neuroscience 158, 1090-1097.
-
(2009)
Neuroscience
, vol.158
, pp. 1090-1097
-
-
Becker, K.J.1
-
10
-
-
0037830589
-
Adoptive transfer of myelin basic protein-tolerized splenocytes to naive animals reduces infarct size: A role for lymphocytes in ischemic brain injury?
-
Becker K., Kindrick D., McCarron R., Hallenbeck J., and, Winn R., (2003) Adoptive transfer of myelin basic protein-tolerized splenocytes to naive animals reduces infarct size: a role for lymphocytes in ischemic brain injury? Stroke 34, 1809-1815.
-
(2003)
Stroke
, vol.34
, pp. 1809-1815
-
-
Becker, K.1
Kindrick, D.2
McCarron, R.3
Hallenbeck, J.4
Winn, R.5
-
11
-
-
0035413361
-
Role of IL-1alpha and IL-1beta in ischemic brain damage
-
Boutin H., LeFeuvre R. A., Horai R., Asano M., Iwakura Y., and, Rothwell N. J., (2001) Role of IL-1alpha and IL-1beta in ischemic brain damage. J. Neurosci. 21, 5528-5534.
-
(2001)
J. Neurosci.
, vol.21
, pp. 5528-5534
-
-
Boutin, H.1
Lefeuvre, R.A.2
Horai, R.3
Asano, M.4
Iwakura, Y.5
Rothwell, N.J.6
-
12
-
-
79957938359
-
Toll-like receptors 2 and 4 in ischemic stroke: Outcome and therapeutic values
-
Brea D., Blanco M., Ramos-Cabrer P., Moldes O., Arias S., Pérez-Mato M., Leira R., Sobrino T., and, Castillo J., (2011) Toll-like receptors 2 and 4 in ischemic stroke: outcome and therapeutic values. J. Cereb. Blood Flow Metab. 31, 1424-1431.
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 1424-1431
-
-
Brea, D.1
Blanco, M.2
Ramos-Cabrer, P.3
Moldes, O.4
Arias, S.5
Pérez-Mato, M.6
Leira, R.7
Sobrino, T.8
Castillo, J.9
-
13
-
-
77952413047
-
Inflammasome signaling at the heart of central nervous system pathology
-
Chakraborty S., Kaushik D. K., Gupta M., and, Basu A., (2010) Inflammasome signaling at the heart of central nervous system pathology. J. Neurosci. Res. 88, 1615-1631.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 1615-1631
-
-
Chakraborty, S.1
Kaushik, D.K.2
Gupta, M.3
Basu, A.4
-
14
-
-
78649526394
-
Sterile inflammation: Sensing and reacting to damage
-
Chen G. Y., and, Nuñez G., (2010) Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 10, 826-837.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 826-837
-
-
Chen, G.Y.1
Nuñez, G.2
-
15
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
Chen C. J., Kono H., Golenbock D., Reed G., Akira S., and, Rock K. L., (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat. Med. 13, 851-856.
-
(2007)
Nat. Med.
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
16
-
-
84856691107
-
An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection
-
Chen F., Liu Z., Wu W., Rozo C., Bowdridge S., Millman A., Van Rooijen N., Urban J. F. Jr, Wynn T. A., and, Gause W. C., (2012) An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat. Med. 18, 260-266.
-
(2012)
Nat. Med.
, vol.18
, pp. 260-266
-
-
Chen, F.1
Liu, Z.2
Wu, W.3
Rozo, C.4
Bowdridge, S.5
Millman, A.6
Van Rooijen, N.7
Urban, Jr.J.F.8
Wynn, T.A.9
Gause, W.C.10
-
17
-
-
78650763016
-
Proteomic investigation of a neural substrate intimately related to brain death
-
Chou J. L., Wu C. H., Tsai C. Y., Chang A. Y., and, Chan S. H., (2011) Proteomic investigation of a neural substrate intimately related to brain death. Proteomics 11, 239-248.
-
(2011)
Proteomics
, vol.11
, pp. 239-248
-
-
Chou, J.L.1
Wu, C.H.2
Tsai, C.Y.3
Chang, A.Y.4
Chan, S.H.5
-
18
-
-
56849129516
-
Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice
-
Clausen B. H., Lambertsen K. L., Babcock A. A., Holm T. H., Dagnaes-Hansen F., and, Finsen B., (2008) Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J. Neuroinflammation 5, 46.
-
(2008)
J. Neuroinflammation
, vol.5
, pp. 46
-
-
Clausen, B.H.1
Lambertsen, K.L.2
Babcock, A.A.3
Holm, T.H.4
Dagnaes-Hansen, F.5
Finsen, B.6
-
19
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
TRANSFORMS Study Group
-
Cohen J. A., Barkhof F., Comi G., et al,. and TRANSFORMS Study Group. (2010) Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N. Engl. J. Med. 362, 402-415.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
-
20
-
-
13344283416
-
Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke
-
Connolly E. S. Jr, Winfree C. J., Springer T. A., Naka Y., Liao H., Yan S. D., Stern D. M., Solomon R. A., Gutierrez-Ramos J. C., and, Pinsky D. J., (1996) Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke. J. Clin. Invest. 97, 209-216.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 209-216
-
-
Connolly, Jr.E.S.1
Winfree, C.J.2
Springer, T.A.3
Naka, Y.4
Liao, H.5
Yan, S.D.6
Stern, D.M.7
Solomon, R.A.8
Gutierrez-Ramos, J.C.9
Pinsky, D.J.10
-
21
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua D. J., Sherlock J., Chen Y., et al,. (2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421, 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
-
22
-
-
79952433204
-
Brain extracellular fluid protein changes in acute stroke patients
-
Dayon L., Turck N., Garcí-Berrocoso T., Walter N., Burkhard P. R., Vilalta A., Sahuquillo J., Montaner J., and, Sanchez J. C., (2011) Brain extracellular fluid protein changes in acute stroke patients. J. Proteome Res. 10, 1043-1051.
-
(2011)
J. Proteome Res.
, vol.10
, pp. 1043-1051
-
-
Dayon, L.1
Turck, N.2
Garcí-Berrocoso, T.3
Walter, N.4
Burkhard, P.R.5
Vilalta, A.6
Sahuquillo, J.7
Montaner, J.8
Sanchez, J.C.9
-
23
-
-
36549047503
-
Brain sphingosine-1-phosphate receptors: Implication for FTY720 in the treatment of multiple sclerosis
-
Dev K. K., Mullershausen F., Mattes H., Kuhn R. R., Bilbe G., Hoyer D., and, Mir A., (2008) Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis. Pharmacol. Ther. 117, 77-93.
-
(2008)
Pharmacol. Ther.
, vol.117
, pp. 77-93
-
-
Dev, K.K.1
Mullershausen, F.2
Mattes, H.3
Kuhn, R.R.4
Bilbe, G.5
Hoyer, D.6
Mir, A.7
-
24
-
-
33846583388
-
Stroke-induced immunodepression: Experimental evidence and clinical relevance
-
Dirnagl U., Klehmet J., Braun J. S., Harms H., Meisel C., Ziemssen T., Prass K., and, Meisel A., (2007) Stroke-induced immunodepression: experimental evidence and clinical relevance. Stroke 38, 770-773.
-
(2007)
Stroke
, vol.38
, pp. 770-773
-
-
Dirnagl, U.1
Klehmet, J.2
Braun, J.S.3
Harms, H.4
Meisel, C.5
Ziemssen, T.6
Prass, K.7
Meisel, A.8
-
25
-
-
81255195550
-
Ischemia and reperfusionâfrom mechanism to translation
-
Eltzschig H. K., and, Eckle T., (2011) Ischemia and reperfusionâ from mechanism to translation. Nat. Med. 17, 1391-1401.
-
(2011)
Nat. Med.
, vol.17
, pp. 1391-1401
-
-
Eltzschig, H.K.1
Eckle, T.2
-
26
-
-
79954802122
-
Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia
-
Famakin B. M., Mou Y., Ruetzler C. A., Bembry J., Maric D., and, Hallenbeck J. M., (2011) Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia. Brain Res. 1388, 148-156.
-
(2011)
Brain Res.
, vol.1388
, pp. 148-156
-
-
Famakin, B.M.1
Mou, Y.2
Ruetzler, C.A.3
Bembry, J.4
Maric, D.5
Hallenbeck, J.M.6
-
27
-
-
84856521251
-
Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury
-
Farrar C. A., Keogh B., McCormack W., O'Shaughnessy A., Parker A., Reilly M., and, Sacks S. H., (2012) Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J. 26, 799-807.
-
(2012)
FASEB J.
, vol.26
, pp. 799-807
-
-
Farrar, C.A.1
Keogh, B.2
McCormack, W.3
O'Shaughnessy, A.4
Parker, A.5
Reilly, M.6
Sacks, S.H.7
-
28
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
Fossiez F., Djossou O., Chomarat P., et al,. (1996) T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183, 2593-2603.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2593-2603
-
-
Fossiez, F.1
Djossou, O.2
Chomarat, P.3
-
29
-
-
80051667284
-
The role of radical generation in increasing cerebrovascular permeability
-
Fraser P. A., (2011) The role of radical generation in increasing cerebrovascular permeability. Free Radic. Biol. Med. 51, 967-977.
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 967-977
-
-
Fraser, P.A.1
-
30
-
-
84861548128
-
Essential role of interleukin-6 in post-stroke angiogenesis
-
Gertz K., Kronenberg G., Kälin R. E., et al,. (2012) Essential role of interleukin-6 in post-stroke angiogenesis. Brain 135, 1964-1980.
-
(2012)
Brain
, vol.135
, pp. 1964-1980
-
-
Gertz, K.1
Kronenberg, G.2
Kälin, R.E.3
-
31
-
-
0036908651
-
The many faces of tumor necrosis factor in stroke
-
Hallenbeck J. M., (2002) The many faces of tumor necrosis factor in stroke. Nat. Med. 8, 1363-1368.
-
(2002)
Nat. Med.
, vol.8
, pp. 1363-1368
-
-
Hallenbeck, J.M.1
-
32
-
-
77449106966
-
Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
-
Hasegawa Y., Suzuki H., Sozen T., Rolland W., and, Zhang J. H., (2010) Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke 41, 368-374.
-
(2010)
Stroke
, vol.41
, pp. 368-374
-
-
Hasegawa, Y.1
Suzuki, H.2
Sozen, T.3
Rolland, W.4
Zhang, J.H.5
-
33
-
-
78149275209
-
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke
-
Hayakawa K., Qiu J., and, Lo E. H., (2010) Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann. N. Y. Acad. Sci. 1207, 50-57.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1207
, pp. 50-57
-
-
Hayakawa, K.1
Qiu, J.2
Lo, E.H.3
-
34
-
-
35448947910
-
T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation
-
Hurn P. D., Subramanian S., Parker S. M., Afentoulis M. E., Kaler L. J., Vandenbark A. A., and, Offner H., (2007) T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation. J. Cereb. Blood Flow Metab. 27, 1798-1805.
-
(2007)
J. Cereb. Blood Flow Metab.
, vol.27
, pp. 1798-1805
-
-
Hurn, P.D.1
Subramanian, S.2
Parker, S.M.3
Afentoulis, M.E.4
Kaler, L.J.5
Vandenbark, A.A.6
Offner, H.7
-
35
-
-
77957858212
-
Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia
-
Hyakkoku K., Hamanaka J., Tsuruma K., Shimazawa M., Tanaka H., Uematsu S., Akira S., Inagaki N., Nagai H., and, Hara H., (2010) Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia. Neuroscience 171, 258-267.
-
(2010)
Neuroscience
, vol.171
, pp. 258-267
-
-
Hyakkoku, K.1
Hamanaka, J.2
Tsuruma, K.3
Shimazawa, M.4
Tanaka, H.5
Uematsu, S.6
Akira, S.7
Inagaki, N.8
Nagai, H.9
Hara, H.10
-
36
-
-
2342614850
-
Neurovascular regulation in the normal brain and in Alzheimer's disease
-
Iadecola C., (2004) Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat. Rev. Neurosci. 5, 347-360.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 347-360
-
-
Iadecola, C.1
-
37
-
-
79960141471
-
The immunology of stroke: From mechanisms to translation
-
Iadecola C., and, Anrather J., (2011) The immunology of stroke: from mechanisms to translation. Nat. Med. 17, 796-808.
-
(2011)
Nat. Med.
, vol.17
, pp. 796-808
-
-
Iadecola, C.1
Anrather, J.2
-
38
-
-
39749173780
-
The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells
-
Ifergan I., Kébir H., Bernard M., Wosik K., Dodelet-Devillers A., Cayrol R., Arbour N., and, Prat A., (2008) The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain 131, 785-799.
-
(2008)
Brain
, vol.131
, pp. 785-799
-
-
Ifergan, I.1
Kébir, H.2
Bernard, M.3
Wosik, K.4
Dodelet-Devillers, A.5
Cayrol, R.6
Arbour, N.7
Prat, A.8
-
39
-
-
0028854369
-
Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex
-
Jander S., Karemer M., Schroeter M., Witte O. W., and, Stoll G., (1995) Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex. J. Cereb. Blood Flow Metab. 15, 42-51.
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 42-51
-
-
Jander, S.1
Karemer, M.2
Schroeter, M.3
Witte, O.W.4
Stoll, G.5
-
40
-
-
84856209632
-
Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke
-
Jung J. E., Kim G. S., and, Chan P. H., (2011) Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. Stroke 42, 3574-3579.
-
(2011)
Stroke
, vol.42
, pp. 3574-3579
-
-
Jung, J.E.1
Kim, G.S.2
Chan, P.H.3
-
41
-
-
79959360656
-
Brain pericytes: Emerging concepts and functional roles in brain homeostasis
-
Kamouchi M., Ago T., and, Kitazono T., (2011) Brain pericytes: emerging concepts and functional roles in brain homeostasis. Cell. Mol. Neurobiol. 31, 175-193.
-
(2011)
Cell. Mol. Neurobiol.
, vol.31
, pp. 175-193
-
-
Kamouchi, M.1
Ago, T.2
Kitazono, T.3
-
42
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H., Kreymborg K., Ifergan I., Dodelet-Devillers A., Cayrol R., Bernard M., Giuliani F., Arbour N., Becher B., and, Prat A., (2007) Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat. Med. 13, 1173-1175.
-
(2007)
Nat. Med.
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
Dodelet-Devillers, A.4
Cayrol, R.5
Bernard, M.6
Giuliani, F.7
Arbour, N.8
Becher, B.9
Prat, A.10
-
43
-
-
33745788420
-
HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain
-
Kim J. B., Sig Choi J., Yu Y. M., Nam K., Piao C. S., Kim S. W., Lee M. H., Han P. L., Park J. S., and, Lee J. K., (2006) HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J. Neurosci. 26, 6413-6421.
-
(2006)
J. Neurosci.
, vol.26
, pp. 6413-6421
-
-
Kim, J.B.1
Sig, C.J.2
Yu, Y.M.3
Nam, K.4
Piao, C.S.5
Kim, S.W.6
Lee, M.H.7
Han, P.L.8
Park, J.S.9
Lee, J.K.10
-
44
-
-
78549273305
-
Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model
-
Konoeda F., Shichita T., Yoshida H., Sugiyama Y., Muto G., Hasegawa E., Morita R., Suzuki N., and, Yoshimura A., (2010) Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model. Biochem. Biophys. Res. Commun. 402, 500-506.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.402
, pp. 500-506
-
-
Konoeda, F.1
Shichita, T.2
Yoshida, H.3
Sugiyama, Y.4
Muto, G.5
Hasegawa, E.6
Morita, R.7
Suzuki, N.8
Yoshimura, A.9
-
45
-
-
10944231103
-
Anti-monocyte chemoattractant protein-1 gene therapy protects against focal brain ischemia in hypertensive rats
-
Kumai Y., Ooboshi H., Takada J., Kamouchi M., Kitazono T., Egashira K., Ibayashi S., and, Iida M., (2004) Anti-monocyte chemoattractant protein-1 gene therapy protects against focal brain ischemia in hypertensive rats. J. Cereb. Blood Flow Metab. 24, 1359-1368.
-
(2004)
J. Cereb. Blood Flow Metab.
, vol.24
, pp. 1359-1368
-
-
Kumai, Y.1
Ooboshi, H.2
Takada, J.3
Kamouchi, M.4
Kitazono, T.5
Egashira, K.6
Ibayashi, S.7
Iida, M.8
-
46
-
-
33745761474
-
Microglia in cerebral ischemia: Molecular actions and interactions
-
Lai A. Y., and, Todd K. G., (2006) Microglia in cerebral ischemia: molecular actions and interactions. Can. J. Physiol. Pharmacol. 84, 49-59.
-
(2006)
Can. J. Physiol. Pharmacol.
, vol.84
, pp. 49-59
-
-
Lai, A.Y.1
Todd, K.G.2
-
47
-
-
71049180369
-
Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
-
Lakhan S. E., Kirchgessner A., and, Hofer M., (2009) Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J. Transl. Med. 7, 97.
-
(2009)
J. Transl. Med.
, vol.7
, pp. 97
-
-
Lakhan, S.E.1
Kirchgessner, A.2
Hofer, M.3
-
48
-
-
4444374308
-
A role for interferon-gamma in focal cerebral ischemia in mice
-
Lambertsen K. L., Gregersen R., Meldgaard M., Clausen B. H., HeibÃl E. K., Ladeby R., Knudsen J., Frandsen A., Owens T., and, Finsen B., (2004) A role for interferon-gamma in focal cerebral ischemia in mice. J. Neuropathol. Exp. Neurol. 63, 942-955.
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 942-955
-
-
Lambertsen, K.L.1
Gregersen, R.2
Meldgaard, M.3
Clausen, B.H.4
Heibãl, E.K.5
Ladeby, R.6
Knudsen, J.7
Frandsen, A.8
Owens, T.9
Finsen, B.10
-
49
-
-
59649123881
-
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
-
Liesz A., Suri-Payer E., Veltkamp C., Doerr H., Sommer C., Rivest S., Giese T., and, Veltkamp R., (2009) Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat. Med. 15, 192-199.
-
(2009)
Nat. Med.
, vol.15
, pp. 192-199
-
-
Liesz, A.1
Suri-Payer, E.2
Veltkamp, C.3
Doerr, H.4
Sommer, C.5
Rivest, S.6
Giese, T.7
Veltkamp, R.8
-
50
-
-
79959300120
-
FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia
-
Liesz A., Sun L., Zhou W., Schwarting S., Mracsko E., Zorn M., Bauer H., Sommer C., and, Veltkamp R., (2011a) FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia. PLoS ONE 6, e21312.
-
(2011)
PLoS ONE
, vol.6
-
-
Liesz, A.1
Sun, L.2
Zhou, W.3
Schwarting, S.4
Mracsko, E.5
Zorn, M.6
Bauer, H.7
Sommer, C.8
Veltkamp, R.9
-
51
-
-
79952175153
-
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
-
Liesz A., Zhou W., Mracskõ Ã., et al,. (2011b) Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke. Brain 134, 704-720.
-
(2011)
Brain
, vol.134
, pp. 704-720
-
-
Liesz, A.1
Zhou, W.2
Mracskõ, Ã.3
-
52
-
-
0028292231
-
Tumor necrosis factor-alpha expression in ischemic neurons
-
Liu T., Clark R. K., McDonnell P. C., Young P. R., White R. F., Barone F. C., and, Feuerstein G. Z., (1994) Tumor necrosis factor-alpha expression in ischemic neurons. Stroke 25, 1481-1488.
-
(1994)
Stroke
, vol.25
, pp. 1481-1488
-
-
Liu, T.1
Clark, R.K.2
McDonnell, P.C.3
Young, P.R.4
White, R.F.5
Barone, F.C.6
Feuerstein, G.Z.7
-
53
-
-
36849076615
-
Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats
-
Liu K., Mori S., Takahashi H. K., et al,. (2007) Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats. FASEB J. 21, 3904-3916.
-
(2007)
FASEB J.
, vol.21
, pp. 3904-3916
-
-
Liu, K.1
Mori, S.2
Takahashi, H.K.3
-
54
-
-
78149292554
-
Degeneration and repair in central nervous system disease
-
Lo E. H., (2010) Degeneration and repair in central nervous system disease. Nat. Med. 16, 1205-1209.
-
(2010)
Nat. Med.
, vol.16
, pp. 1205-1209
-
-
Lo, E.H.1
-
55
-
-
79954579638
-
Stroke and the immune system: From pathophysiology to new therapeutic strategies
-
Macrez R., Ali C., Toutirais O., Le Mauff B., Defer G., Dirnagl U., and, Vivien D., (2011) Stroke and the immune system: from pathophysiology to new therapeutic strategies. Lancet Neurol. 10, 471-480.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 471-480
-
-
MacRez, R.1
Ali, C.2
Toutirais, O.3
Le Mauff, B.4
Defer, G.5
Dirnagl, U.6
Vivien, D.7
-
56
-
-
59349116736
-
Toll-like receptor signaling in endogenous neuroprotection and stroke
-
Marsh B. J., Williams-Karnesky R. L., and, Stenzel-Poore M. P., (2009) Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience 158, 1007-1020.
-
(2009)
Neuroscience
, vol.158
, pp. 1007-1020
-
-
Marsh, B.J.1
Williams-Karnesky, R.L.2
Stenzel-Poore, M.P.3
-
57
-
-
68649126866
-
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
-
Martin B., Hirota K., Cua D. J., Stockinger B., and, Veldhoen M., (2009) Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity 31, 321-330.
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
Stockinger, B.4
Veldhoen, M.5
-
58
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1beta
-
Martinon F., Burns K., and, Tschopp J., (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-1beta. Mol. Cell 10, 417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
59
-
-
82555196087
-
Suppressing immunosuppression after stroke
-
Meisel C., and, Meisel A., (2011) Suppressing immunosuppression after stroke. N. Engl. J. Med. 365, 2134-2136.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2134-2136
-
-
Meisel, C.1
Meisel, A.2
-
60
-
-
78149238637
-
Metalloproteinase and stroke infarct size: Role for anti-inflammatory treatment?
-
Morancho A., Rosell A., Garcia-Bonilla L., and, Montaner J., (2010) Metalloproteinase and stroke infarct size: role for anti-inflammatory treatment? Ann. N. Y. Acad. Sci. 1207, 123-133.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1207
, pp. 123-133
-
-
Morancho, A.1
Rosell, A.2
Garcia-Bonilla, L.3
Montaner, J.4
-
61
-
-
77955487488
-
The science of stroke: Mechanisms in search of treatments
-
Moskowitz M. A., Lo E. H., and, Iadecola C., (2010) The science of stroke: mechanisms in search of treatments. Neuron 67, 181-198.
-
(2010)
Neuron
, vol.67
, pp. 181-198
-
-
Moskowitz, M.A.1
Lo, E.H.2
Iadecola, C.3
-
62
-
-
79954992071
-
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4 T cells
-
Motomura Y., Kitamura H., Hijikata A., et al,. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4 T cells. Nat. Immunol. 12, 450-459.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 450-459
-
-
Motomura, Y.1
Kitamura, H.2
Hijikata, A.3
-
63
-
-
33646874015
-
Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages
-
Offner H., Subramanian S., Parker S. M., Wang C., Afentoulis M. E., Lewis A., Vandenbark A. A., and, Hurn P. D., (2006) Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages. J. Immunol. 176, 6523-6531.
-
(2006)
J. Immunol.
, vol.176
, pp. 6523-6531
-
-
Offner, H.1
Subramanian, S.2
Parker, S.M.3
Wang, C.4
Afentoulis, M.E.5
Lewis, A.6
Vandenbark, A.A.7
Hurn, P.D.8
-
64
-
-
69549124480
-
CD4 + CD25-LAG3 + regulatory T cells controlled by the transcription factor Egr-2
-
Okamura T., Fujio K., Shibuya M., Sumitomo S., Shoda H., Sakaguchi S., and, Yamamoto K., (2009) CD4 + CD25-LAG3 + regulatory T cells controlled by the transcription factor Egr-2. Proc. Natl Acad. Sci. USA 106, 13974-13979.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 13974-13979
-
-
Okamura, T.1
Fujio, K.2
Shibuya, M.3
Sumitomo, S.4
Shoda, H.5
Sakaguchi, S.6
Yamamoto, K.7
-
65
-
-
20044368016
-
Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia
-
Ooboshi H., Ibayashi S., Shichita T., et al,. (2006) Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia. Circulation 111, 913-919.
-
(2006)
Circulation
, vol.111
, pp. 913-919
-
-
Ooboshi, H.1
Ibayashi, S.2
Shichita, T.3
-
66
-
-
20944435890
-
Emerging roles of thioredoxin cycle enzymes in the central nervous system
-
Patenaude A., Murthy M. R., and, Mirault M. E., (2005) Emerging roles of thioredoxin cycle enzymes in the central nervous system. Cell. Mol. Life Sci. 62, 1063-1080.
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1063-1080
-
-
Patenaude, A.1
Murthy, M.R.2
Mirault, M.E.3
-
67
-
-
79953139969
-
Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice
-
Pfeilschifter W., Czech-Zechmeister B., Sujak M., Foerch C., Wichelhaus T. A., and, Pfeilschifter J., (2011) Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice. Exp. Transl. Stroke Med. 3, 2.
-
(2011)
Exp. Transl. Stroke Med.
, vol.3
, pp. 2
-
-
Pfeilschifter, W.1
Czech-Zechmeister, B.2
Sujak, M.3
Foerch, C.4
Wichelhaus, T.A.5
Pfeilschifter, J.6
-
68
-
-
42549139329
-
Early release of HMGB-1 from neurons after the onset of brain ischemia
-
Qiu J., Nishimura M., Wang Y., Sims J. R., Qiu S., Savitz S. I., Salomone S., and, Moskowitz M. A., (2008) Early release of HMGB-1 from neurons after the onset of brain ischemia. J. Cereb. Blood Flow Metab. 28, 927-938.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 927-938
-
-
Qiu, J.1
Nishimura, M.2
Wang, Y.3
Sims, J.R.4
Qiu, S.5
Savitz, S.I.6
Salomone, S.7
Moskowitz, M.A.8
-
69
-
-
70349868418
-
Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo
-
Rashidian J., Rousseaux M. W., Venderova K., et al,. (2009) Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. J. Neurosci. 29, 12497-12505.
-
(2009)
J. Neurosci.
, vol.29
, pp. 12497-12505
-
-
Rashidian, J.1
Rousseaux, M.W.2
Venderova, K.3
-
70
-
-
84858688293
-
Regulation of inflammasome signaling
-
Rathinum V. A., Vanaja S. K., and, Fitzgerald K. A., (2012) Regulation of inflammasome signaling. Nat. Immunol. 13, 333-342.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 333-342
-
-
Rathinum, V.A.1
Vanaja, S.K.2
Fitzgerald, K.A.3
-
71
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi A., Coisne C., Baumjohann D., Benvenuto F., Bottinelli D., Lira S., Uccelli A., Lanzavecchia A., Engelhardt B., and, Sallusto F., (2009) C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat. Immunol. 10, 514-523.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
Benvenuto, F.4
Bottinelli, D.5
Lira, S.6
Uccelli, A.7
Lanzavecchia, A.8
Engelhardt, B.9
Sallusto, F.10
-
72
-
-
79958265647
-
Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke
-
Ren X., Akiyoshi K., Dziennis S., Vandenbark A. A., Herson P. S., Hurn P. D., and, Offner H., (2011) Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke. J. Neurosci. 31, 8556-8563.
-
(2011)
J. Neurosci.
, vol.31
, pp. 8556-8563
-
-
Ren, X.1
Akiyoshi, K.2
Dziennis, S.3
Vandenbark, A.A.4
Herson, P.S.5
Hurn, P.D.6
Offner, H.7
-
73
-
-
66449130960
-
Regulation of innate immune responses in the brain
-
Rivest S., (2009) Regulation of innate immune responses in the brain. Nat. Rev. Immunol. 9, 429-439.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 429-439
-
-
Rivest, S.1
-
74
-
-
0028597088
-
Local immune responses in the rat middle cerebral artery occlusion
-
Schroeter M., Jander S., Witte O. W., and, Stoll G., (1994) Local immune responses in the rat middle cerebral artery occlusion. J. Neuroimmunol. 55, 195-203.
-
(1994)
J. Neuroimmunol.
, vol.55
, pp. 195-203
-
-
Schroeter, M.1
Jander, S.2
Witte, O.W.3
Stoll, G.4
-
75
-
-
68349160698
-
Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
-
Shichita T., Sugiyama Y., Ooboshi H., et al,. (2009) Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat. Med. 15, 946-950.
-
(2009)
Nat. Med.
, vol.15
, pp. 946-950
-
-
Shichita, T.1
Sugiyama, Y.2
Ooboshi, H.3
-
76
-
-
84861999263
-
Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain
-
Shichita T., Hasegawa E., Kimura A., et al,. (2012) Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain. Nat. Med. 18, 911-918.
-
(2012)
Nat. Med.
, vol.18
, pp. 911-918
-
-
Shichita, T.1
Hasegawa, E.2
Kimura, A.3
-
77
-
-
0032930869
-
Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury
-
Soriano S. G., Coxon A., Wang Y. F., Frosch M. P., Lipton S. A., Hickey P. R., and, Mayadas T. N., (1999) Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. Stroke 30, 134-139.
-
(1999)
Stroke
, vol.30
, pp. 134-139
-
-
Soriano, S.G.1
Coxon, A.2
Wang, Y.F.3
Frosch, M.P.4
Lipton, S.A.5
Hickey, P.R.6
Mayadas, T.N.7
-
78
-
-
84863157872
-
Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injury
-
Stetler R. A., Gao Y., Zhang L., et al,. (2012) Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injury. J. Neurosci. 32, 2667-2682.
-
(2012)
J. Neurosci.
, vol.32
, pp. 2667-2682
-
-
Stetler, R.A.1
Gao, Y.2
Zhang, L.3
-
79
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart C. R., Stuart L. M., Wilkinson K., et al,. (2010) CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat. Immunol. 11, 155-161.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
-
80
-
-
80054840927
-
Monocyte chemoattractant protein-1-deficiency impairs the expression of IL-6, IL-1b and G-CSF after transient focal ischemia in mice
-
Strecker J. K., Minnerup J., Gess B., Ringelstein E. B., Schäbitz W. R., and, Schilling M., (2011) Monocyte chemoattractant protein-1-deficiency impairs the expression of IL-6, IL-1b and G-CSF after transient focal ischemia in mice. PLoS ONE 6, e25863.
-
(2011)
PLoS ONE
, vol.6
-
-
Strecker, J.K.1
Minnerup, J.2
Gess, B.3
Ringelstein, E.B.4
Schäbitz, W.R.5
Schilling, M.6
-
81
-
-
67650070642
-
Recombinant T cell receptor ligand treats experimental stroke
-
Subramanian S., Zhang B., Kosaka Y., Burrows G. G., Grafe M. R., Vandenbark A. A., Hurn P. D., and, Offner H., (2009) Recombinant T cell receptor ligand treats experimental stroke. Stroke 40, 2539-2545.
-
(2009)
Stroke
, vol.40
, pp. 2539-2545
-
-
Subramanian, S.1
Zhang, B.2
Kosaka, Y.3
Burrows, G.G.4
Grafe, M.R.5
Vandenbark, A.A.6
Hurn, P.D.7
Offner, H.8
-
82
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton C. E., Lalor S. J., Sweeney C. M., Brereton C. F., Lavelle E. C., and, Mills K. H., (2009) Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
83
-
-
62949143181
-
Astrocytes and ischemic injury
-
Takano T., Oberheim N., Cotrina M. L., and, Nedergaard M., (2009) Astrocytes and ischemic injury. Stroke 40, S8-S12.
-
(2009)
Stroke
, vol.40
-
-
Takano, T.1
Oberheim, N.2
Cotrina, M.L.3
Nedergaard, M.4
-
84
-
-
35348860696
-
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
-
Tang S. C., Arumugam T. V., Xu X., et al,. (2007) Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc. Natl Acad. Sci. USA 104, 13798-13803.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 13798-13803
-
-
Tang, S.C.1
Arumugam, T.V.2
Xu, X.3
-
85
-
-
52449112645
-
Blood cell-derived RANTES mediates cerebral microvascular dysfunction, inflammation, and tissue injury after focal ischemia-reperfusion
-
Terao S., Yilmaz G., Stokes K. Y., Russell J., Ishikawa M., Kawase T., and, Granger D. N., (2008) Blood cell-derived RANTES mediates cerebral microvascular dysfunction, inflammation, and tissue injury after focal ischemia-reperfusion. Stroke 39, 2560-2570.
-
(2008)
Stroke
, vol.39
, pp. 2560-2570
-
-
Terao, S.1
Yilmaz, G.2
Stokes, K.Y.3
Russell, J.4
Ishikawa, M.5
Kawase, T.6
Granger, D.N.7
-
86
-
-
64249155625
-
Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia
-
Terao Y., Ohta H., Oda A., Nakagaito Y., Kiyota Y., and, Shintani Y., (2009) Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia. Neurosci. Res. 64, 75-82.
-
(2009)
Neurosci. Res.
, vol.64
, pp. 75-82
-
-
Terao, Y.1
Ohta, H.2
Oda, A.3
Nakagaito, Y.4
Kiyota, Y.5
Shintani, Y.6
-
87
-
-
38149044364
-
Analysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke
-
Vogelgesang A., Grunwald U., Langner S., Jack R., Bröker B. M., Kessler C., and, Dressel A., (2008) Analysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke. Stroke 39, 237-241.
-
(2008)
Stroke
, vol.39
, pp. 237-241
-
-
Vogelgesang, A.1
Grunwald, U.2
Langner, S.3
Jack, R.4
Bröker, B.M.5
Kessler, C.6
Dressel, A.7
-
88
-
-
79551495392
-
Fingolimod provides long-term protection in rodent models of cerebral ischemia
-
Wei Y., Yemisci M., Kim H. H., et al,. (2011) Fingolimod provides long-term protection in rodent models of cerebral ischemia. Ann. Neurol. 69, 119-129.
-
(2011)
Ann. Neurol.
, vol.69
, pp. 119-129
-
-
Wei, Y.1
Yemisci, M.2
Kim, H.H.3
-
89
-
-
0141819958
-
The stress response: Implications for the clinical development of hsp90 inhibitors
-
Whitesell L., Bagatell R., and, Falsey R., (2003) The stress response: implications for the clinical development of hsp90 inhibitors. Curr. Cancer Drug Targets 3, 349-358.
-
(2003)
Curr. Cancer Drug Targets
, vol.3
, pp. 349-358
-
-
Whitesell, L.1
Bagatell, R.2
Falsey, R.3
-
90
-
-
80053604734
-
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke
-
Wong C. H., Jenne C. N., Leger C., and, Kubes P., (2011) Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science 334, 101-105.
-
(2011)
Science
, vol.334
, pp. 101-105
-
-
Wong, C.H.1
Jenne, C.N.2
Leger, C.3
Kubes, P.4
-
91
-
-
0037222255
-
Structure, mechanism and regulation of peroxiredoxins
-
Wood Z. A., Schröder E., Robin Harris J., and, Poole L. B., (2003) Structure, mechanism and regulation of peroxiredoxins. Trends Biochem. Sci. 28, 32-40.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 32-40
-
-
Wood, Z.A.1
Schröder, E.2
Robin, H.J.3
Poole, L.B.4
-
92
-
-
79959999864
-
Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia
-
Xiong X., Barreto G. E., Xu L., Ouyang Y. B., Xie X., and, Giffard R. G., (2011) Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia. Stroke 42, 2026-2032.
-
(2011)
Stroke
, vol.42
, pp. 2026-2032
-
-
Xiong, X.1
Barreto, G.E.2
Xu, L.3
Ouyang, Y.B.4
Xie, X.5
Giffard, R.G.6
-
93
-
-
24744468600
-
JAK/STAT3 pathway is involved in survival of neurons in response to insulin like growth factor and negatively regulated by suppressor of cytokine signal-3
-
Yadav A., Kalita A., Dhillon S., and, Banerjee K., (2005) JAK/STAT3 pathway is involved in survival of neurons in response to insulin like growth factor and negatively regulated by suppressor of cytokine signal-3. J. Biol. Chem. 280, 31830-31840.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31830-31840
-
-
Yadav, A.1
Kalita, A.2
Dhillon, S.3
Banerjee, K.4
-
94
-
-
22244468321
-
Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: Possible involvement of Stat3 activation in the protection of neurons
-
Yamashita T., Sawamoto K., Suzuki S., Suzuki N., Adachi K., Kawase T., Mihara M., Ohsugi Y., Abe K., and, Okano H., (2005) Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J. Neurochem. 94, 459-468.
-
(2005)
J. Neurochem.
, vol.94
, pp. 459-468
-
-
Yamashita, T.1
Sawamoto, K.2
Suzuki, S.3
Suzuki, N.4
Adachi, K.5
Kawase, T.6
Mihara, M.7
Ohsugi, Y.8
Abe, K.9
Okano, H.10
-
95
-
-
70449092388
-
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
-
Yanai H., Ban T., Wang Z., et al,. (2009) HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462, 99-103.
-
(2009)
Nature
, vol.462
, pp. 99-103
-
-
Yanai, H.1
Ban, T.2
Wang, Z.3
-
96
-
-
79551627378
-
HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signaling
-
Yang Q. W., Lu F. L., Zhou Y., Wang L., Zhong Q., Lin S., Xiang J., Li J. C., Fang C. Q., and, Wang J. Z., (2011) HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signaling. J. Cereb. Blood Flow Metab. 31, 593-605.
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 593-605
-
-
Yang, Q.W.1
Lu, F.L.2
Zhou, Y.3
Wang, L.4
Zhong, Q.5
Lin, S.6
Xiang, J.7
Li, J.C.8
Fang, C.Q.9
Wang, J.Z.10
-
97
-
-
33646454450
-
Role of T lymphocytes and interferon-gamma in ischemic stroke
-
Yilmaz G., Arumugam T. V., Stokes K. Y., and, Granger D. N., (2006) Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation 113, 2105-2112.
-
(2006)
Circulation
, vol.113
, pp. 2105-2112
-
-
Yilmaz, G.1
Arumugam, T.V.2
Stokes, K.Y.3
Granger, D.N.4
-
98
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q., Raoof M., Chen Y., Sumi Y., Sursal T., Junger W., Brohi K., Itagaki K., and, Hauser C. J., (2010) Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464, 104-107.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
Junger, W.6
Brohi, K.7
Itagaki, K.8
Hauser, C.J.9
-
99
-
-
79955473647
-
Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats
-
Zhang J., Takahashi H. K., Liu K., et al,. (2011) Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats. Stroke 42, 1420-1428.
-
(2011)
Stroke
, vol.42
, pp. 1420-1428
-
-
Zhang, J.1
Takahashi, H.K.2
Liu, K.3
-
100
-
-
37549004821
-
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke
-
Zheng K., Kim J. Y., Ma H., Lee J. E., and, Yenari M. A., (2008) Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J. Cereb. Blood Flow Metab. 28, 53-63.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 53-63
-
-
Zheng, K.1
Kim, J.Y.2
Ma, H.3
Lee, J.E.4
Yenari, M.A.5
-
101
-
-
32144461723
-
Stroke and neurovascular protection
-
del Zoppo G. J., (2006) Stroke and neurovascular protection. N. Engl. J. Med. 354, 553-555.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 553-555
-
-
Del Zoppo, G.J.1
|