Phosphorylation of HSP27 by protein Kinase D is essential for mediating neuroprotection against ischemic neuronal injury

Journal of Neuroscience

Volumn 32, Issue 8, 2012, Pages 2667-2682

  Stetler, R Anne ^a,b,c   Gao, Yanqin ^b,c   Zhang, Lili ^a,c   Weng, Zhongfang ^a,c   Zhang, Feng ^a,c   Hu, Xiaoming ^a,c   Wang, Suping ^a,c   Vosler, Peter ^a,c   Cao, Guodong ^a,b,c   Sun, Dandan ^a,c   Graham, Steven H ^a,c   Chen, Jun ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; APOPTOSIS SIGNAL REGULATING KINASE 1; ASPARTIC ACID; HEAT SHOCK PROTEIN 27; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR; PROTEIN KINASE D; RECOMBINANT PROTEIN; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; ENZYME ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SUCROSE GRADIENT; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; ANOXIA; BRAIN ISCHEMIA; CELLS, CULTURED; CEREBRAL CORTEX; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLUCOSE; HSP27 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; L-LACTATE DEHYDROGENASE; LASER-DOPPLER FLOWMETRY; MALE; MAP KINASE KINASE KINASE 5; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN KINASE C; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84863157872     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5169-11.2012     Document Type: Article

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