메뉴 건너뛰기




Volumn 136, Issue 2, 2012, Pages 175-185

Oxidative stress and macrophage foam cell formation during diabetes mellitus-induced atherogenesis: Role of insulin therapy

Author keywords

Atherosclerosis; Cholesterol; Diabetes mellitus; Insulin; Oxidative stress; Paraoxonases

Indexed keywords

APOLIPOPROTEIN B; ARYLDIALKYLPHOSPHATASE; ARYLDIALKYLPHOSPHATASE 1; ARYLDIALKYLPHOSPHATASE 2; CD36 ANTIGEN; CHOLESTEROL; DIACYLGLYCEROL ACYLTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNINDEXED DRUG; VERY LOW DENSITY LIPOPROTEIN;

EID: 84867335958     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.08.002     Document Type: Review
Times cited : (70)

References (114)
  • 1
    • 0032960337 scopus 로고    scopus 로고
    • Effect of diabetes mellitus on formation of coronary collateral vessels
    • A. Abaci, A. Oǧuzhan, S. Kahraman, N.K. Eryol, S. Unal, and H. Arinc Effect of diabetes mellitus on formation of coronary collateral vessels Circulation 99 1999 2239 2242
    • (1999) Circulation , vol.99 , pp. 2239-2242
    • Abaci, A.1    Oǧuzhan, A.2    Kahraman, S.3    Eryol, N.K.4    Unal, S.5    Arinc, H.6
  • 2
    • 0028883658 scopus 로고
    • Serum paraoxonase activity, concentration and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoprotein
    • C.A. Abbott, M.I. Mackness, S. Kumar, A.J. Boulton, and P.N. Durrington Serum paraoxonase activity, concentration and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoprotein Arterioscler Thromb Vasc Biol 11 1995 1812 1818
    • (1995) Arterioscler Thromb Vasc Biol , vol.11 , pp. 1812-1818
    • Abbott, C.A.1    MacKness, M.I.2    Kumar, S.3    Boulton, A.J.4    Durrington, P.N.5
  • 3
    • 21444454887 scopus 로고    scopus 로고
    • Molecular targets of diabetic cardiovascular complications
    • F.K. Ahmad, H. Zhiheng, and G.L. King Molecular targets of diabetic cardiovascular complications Curr Drug Targets 6 2005 487 494
    • (2005) Curr Drug Targets , vol.6 , pp. 487-494
    • Ahmad, F.K.1    Zhiheng, H.2    King, G.L.3
  • 4
    • 47049118693 scopus 로고    scopus 로고
    • High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients
    • T. Albacker, G. Carvalho, T. Schricker, and K. Lachapelle High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients Ann Thorac Surg 86 2008 20 27
    • (2008) Ann Thorac Surg , vol.86 , pp. 20-27
    • Albacker, T.1    Carvalho, G.2    Schricker, T.3    Lachapelle, K.4
  • 5
    • 0033950472 scopus 로고    scopus 로고
    • Effect of insulin on human aortic endothelial nitric oxide synthase
    • A. Aljada, and P. Dandona Effect of insulin on human aortic endothelial nitric oxide synthase Metabolism 49 2000 147 150
    • (2000) Metabolism , vol.49 , pp. 147-150
    • Aljada, A.1    Dandona, P.2
  • 6
    • 0034746443 scopus 로고    scopus 로고
    • Insulin inhibits NF-kappaB and MCP-1 expression in human aortic endothelial cells
    • A. Aljada, H. Ghanim, R. Saadeh, and P. Dandona Insulin inhibits NF-kappaB and MCP-1 expression in human aortic endothelial cells J Clin Endocrinol Metab 86 2001 450 453
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 450-453
    • Aljada, A.1    Ghanim, H.2    Saadeh, R.3    Dandona, P.4
  • 7
    • 1042268046 scopus 로고    scopus 로고
    • Nutrition Principles and Recommendations in Diabetes
    • American Diabetes Association
    • American Diabetes Association Nutrition Principles and Recommendations in Diabetes Diabetes Care 27 Suppl. 1 2004, January s36
    • (2004) Diabetes Care , vol.27 , Issue.SUPPL. 1 , pp. 36
  • 8
    • 0035928391 scopus 로고    scopus 로고
    • Type 1 diabetes: New perspectives on disease pathogenesis and treatment
    • M.A. Atkinson, and G.S. Eisenbarth Type 1 diabetes: New perspectives on disease pathogenesis and treatment Lancet 358 2001 221 229
    • (2001) Lancet , vol.358 , pp. 221-229
    • Atkinson, M.A.1    Eisenbarth, G.S.2
  • 9
    • 0033301270 scopus 로고    scopus 로고
    • Macrophage foam cell formation during early atherogenesis is determined by the balance between pro-oxidants and anti-oxidants in arterial cells and blood lipoproteins
    • M. Aviram Macrophage foam cell formation during early atherogenesis is determined by the balance between pro-oxidants and anti-oxidants in arterial cells and blood lipoproteins Antioxid Redox Signal 1 1999 585 594
    • (1999) Antioxid Redox Signal , vol.1 , pp. 585-594
    • Aviram, M.1
  • 10
    • 0034013311 scopus 로고    scopus 로고
    • Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: Studies in humans and in atherosclerotic apolipoprotein E-deficient mice
    • M. Aviram, L. Dornfeld, M. Rosenblat, N. Volkova, M. Kaplan, and R. Coleman Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: Studies in humans and in atherosclerotic apolipoprotein E-deficient mice Am J Clin Nutr 71 2000 1062 1076
    • (2000) Am J Clin Nutr , vol.71 , pp. 1062-1076
    • Aviram, M.1    Dornfeld, L.2    Rosenblat, M.3    Volkova, N.4    Kaplan, M.5    Coleman, R.6
  • 11
    • 0036296295 scopus 로고    scopus 로고
    • Wine flavonoids protect against LDL oxidation and atherosclerosis
    • M. Aviram, and B. Fuhrman Wine flavonoids protect against LDL oxidation and atherosclerosis Ann N Y Acad Sci 957 2002 146 161
    • (2002) Ann N y Acad Sci , vol.957 , pp. 146-161
    • Aviram, M.1    Fuhrman, B.2
  • 12
    • 5344238178 scopus 로고    scopus 로고
    • Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development
    • M. Aviram, and M. Rosenblat Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development Free Radic Biol Med 37 2004 1304 1316
    • (2004) Free Radic Biol Med , vol.37 , pp. 1304-1316
    • Aviram, M.1    Rosenblat, M.2
  • 13
    • 22544469174 scopus 로고    scopus 로고
    • Paraoxonases and cardiovascular diseases: Pharmacological and nutritional influences
    • M. Aviram, and M. Rosenblat Paraoxonases and cardiovascular diseases: pharmacological and nutritional influences Curr Opin Lipidol 16 2005 393 399
    • (2005) Curr Opin Lipidol , vol.16 , pp. 393-399
    • Aviram, M.1    Rosenblat, M.2
  • 14
    • 67049099187 scopus 로고    scopus 로고
    • Hyperlipidaemia and cardiovascular disease: Inflammation andoxidative stress in diabetic patients
    • M. Aviram Hyperlipidaemia and cardiovascular disease: Inflammation andoxidative stress in diabetic patients Curr Opin Lipidol 20 2009 258 259
    • (2009) Curr Opin Lipidol , vol.20 , pp. 258-259
    • Aviram, M.1
  • 15
    • 39949085776 scopus 로고    scopus 로고
    • Oxidative stress and vascular disease in diabetes: Is the dichotomization of insulin signaling still valid?
    • A. Avogaro, S.V. de Kreutzenberg, and G.P. Fadini Oxidative stress and vascular disease in diabetes: Is the dichotomization of insulin signaling still valid? Free Radic Biol Med 44 2008 1209 1215
    • (2008) Free Radic Biol Med , vol.44 , pp. 1209-1215
    • Avogaro, A.1    De Kreutzenberg, S.V.2    Fadini, G.P.3
  • 16
    • 4043058031 scopus 로고    scopus 로고
    • Advanced end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes
    • G. Basta, A.M. Schmidt, and R. De Caterina Advanced end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes Cardiovasc Res 63 2004 582 592
    • (2004) Cardiovasc Res , vol.63 , pp. 582-592
    • Basta, G.1    Schmidt, A.M.2    De Caterina, R.3
  • 17
    • 77951529201 scopus 로고    scopus 로고
    • Vitamin e reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype
    • S. Blum, M. Vardi, J.B. Brown, A. Russell, U. Milman, and C. Shapira Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype Pharmacogenomics 11 2010 675 684
    • (2010) Pharmacogenomics , vol.11 , pp. 675-684
    • Blum, S.1    Vardi, M.2    Brown, J.B.3    Russell, A.4    Milman, U.5    Shapira, C.6
  • 18
    • 65649098029 scopus 로고    scopus 로고
    • Phosphorylation of IRS proteins, insulin action, and insulin resistance
    • S. Boura-Halfon, and Y. Zick Phosphorylation of IRS proteins, insulin action, and insulin resistance Am J Physiol Endocrinol Metab 296 2009 E581 E591
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Boura-Halfon, S.1    Zick, Y.2
  • 19
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • M.S. Brown, and J.L. Goldstein The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor Cell 89 1997 331 340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 20
    • 0035724855 scopus 로고    scopus 로고
    • Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event
    • A.M. Brown, and G.F. Gibbons Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event Arterioscler Thromb Vasc Biol 21 2001 1656 1661
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1656-1661
    • Brown, A.M.1    Gibbons, G.F.2
  • 21
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry of and molecular biology of diabetic complications
    • M. Brownlee Biochemistry of and molecular biology of diabetic complications Nature 414 2001 813 820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 22
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • M. Brownlee The pathobiology of diabetic complications: a unifying mechanism Diabetes 54 2005 1615 1625
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 23
    • 80053586942 scopus 로고    scopus 로고
    • Excess exposure to insulin is the primary cause of insulin resistance and its associated atherosclerosis
    • W. Cao, J. Ning, X. Yang, and Z. Liu Excess exposure to insulin is the primary cause of insulin resistance and its associated atherosclerosis Curr Mol Pharmacol 4 2011 154 166
    • (2011) Curr Mol Pharmacol , vol.4 , pp. 154-166
    • Cao, W.1    Ning, J.2    Yang, X.3    Liu, Z.4
  • 24
  • 25
    • 2942750058 scopus 로고    scopus 로고
    • Atherogenic lipoprotein particles in atherosclerosis
    • R. Carmena, P. Duriez, and J.C. Fruchart Atherogenic lipoprotein particles in atherosclerosis Circulation 109 2004 III2 III7
    • (2004) Circulation , vol.109
    • Carmena, R.1    Duriez, P.2    Fruchart, J.C.3
  • 26
    • 75549083004 scopus 로고    scopus 로고
    • Antioxidant anti-inflammatory treatment in type 2 diabetes
    • A. Ceriello, and R. Testa Antioxidant anti-inflammatory treatment in type 2 diabetes Diabetes Care 32 2009 S232 S236
    • (2009) Diabetes Care , vol.32
    • Ceriello, A.1    Testa, R.2
  • 27
    • 66349086461 scopus 로고    scopus 로고
    • Diabetes and atherosclerosis: Is there a role for hyperglycemia?
    • A. Chait, and K.E. Bornfeldt Diabetes and atherosclerosis: Is there a role for hyperglycemia? J Lipid Res 50 2009 S335 S339
    • (2009) J Lipid Res , vol.50
    • Chait, A.1    Bornfeldt, K.E.2
  • 28
    • 20944436002 scopus 로고    scopus 로고
    • Advances in diabetes for the millennium: Vitamins and oxidant stress in diabetes and its complications
    • B. Chertow Advances in diabetes for the millennium: Vitamins and oxidant stress in diabetes and its complications MedGenMed 6 Suppl. 3 2004 4
    • (2004) MedGenMed , vol.6 , Issue.SUPPL. 3 , pp. 4
    • Chertow, B.1
  • 30
    • 0028858162 scopus 로고
    • Acute hyperinsulinemia decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM
    • M.H. Cummings, G.F. Watts, A.M. Umpleby, T.R. Hennessy, J.M. Kelly, and N.C. Jackson Acute hyperinsulinemia decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM Diabetes 44 1995 1059 1065
    • (1995) Diabetes , vol.44 , pp. 1059-1065
    • Cummings, M.H.1    Watts, G.F.2    Umpleby, A.M.3    Hennessy, T.R.4    Kelly, J.M.5    Jackson, N.C.6
  • 31
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kappaB and stimulates I-kappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • P. Dandona, A. Aljada, P. Mohanty, H. Ghanim, W. Hamouda, and E. Assian Insulin inhibits intranuclear nuclear factor kappaB and stimulates I-kappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86 2001 3257 3265
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    Assian, E.6
  • 34
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus N Engl J Med 329 1993 977 986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 35
    • 33645509709 scopus 로고    scopus 로고
    • Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
    • X. Du, D. Edelstein, S. Obici, N. Higham, M.H. Zou, and M. Brownlee Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation J Clin Invest 116 2006 1071 1080
    • (2006) J Clin Invest , vol.116 , pp. 1071-1080
    • Du, X.1    Edelstein, D.2    Obici, S.3    Higham, N.4    Zou, M.H.5    Brownlee, M.6
  • 36
    • 0034012271 scopus 로고    scopus 로고
    • Significant improvement of apolipoprotein B-containing lipoprotein metabolism by insulin treatment in patients with non-insulin-dependent diabetes mellitus
    • L. Duvillard, F. Pont, E. Florentin, P. Gambert, and B. Vergès Significant improvement of apolipoprotein B-containing lipoprotein metabolism by insulin treatment in patients with non-insulin-dependent diabetes mellitus Diabetologia 43 1 2000 27 35
    • (2000) Diabetologia , vol.43 , Issue.1 , pp. 27-35
    • Duvillard, L.1    Pont, F.2    Florentin, E.3    Gambert, P.4    Vergès, B.5
  • 37
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • J.L. Evans, I.D. Goldfine, B.A. Maddux, and G.M. Grodsky Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes Endocr Rev 23 2002 599 622
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 38
    • 0024561103 scopus 로고
    • Importance of small intestine in diabetic hypercholesterolemia
    • K.R. Feingold Importance of small intestine in diabetic hypercholesterolemia Diabetes 38 1989 141 145
    • (1989) Diabetes , vol.38 , pp. 141-145
    • Feingold, K.R.1
  • 39
    • 1342343976 scopus 로고    scopus 로고
    • Diabetes and atherogenesis
    • M. Fisher Diabetes and atherogenesis Heart 90 2004 336 340
    • (2004) Heart , vol.90 , pp. 336-340
    • Fisher, M.1
  • 40
    • 72949112222 scopus 로고    scopus 로고
    • High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx
    • A. Gantman, B. Fuhrman, M. Aviram, and T. Hayek High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx Biochem Biophys Res Commun 391 2010 523 528
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 523-528
    • Gantman, A.1    Fuhrman, B.2    Aviram, M.3    Hayek, T.4
  • 41
    • 57749105450 scopus 로고    scopus 로고
    • Selective regulation of heme oxygenase-1 expression and function by insulin through IRS1/ phosphoinositide 3-kinase/Akt2 pathway
    • P. Geraldes, K. Yagi, Y. Ohshiro, Z. He, Y. Maeno, and J. Yamamoto-Hiraoka Selective regulation of heme oxygenase-1 expression and function by insulin through IRS1/ phosphoinositide 3-kinase/Akt2 pathway J Biol Chem 283 2008 34327 34336
    • (2008) J Biol Chem , vol.283 , pp. 34327-34336
    • Geraldes, P.1    Yagi, K.2    Ohshiro, Y.3    He, Z.4    Maeno, Y.5    Yamamoto-Hiraoka, J.6
  • 42
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • F. Giacco, and M. Brownlee Oxidative stress and diabetic complications Circ Res 107 2010 1058 1070
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 43
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolics composition and processing
    • M.L. Gil, F.A. Tomas-Barberan, B. Hess-Pierce, D.M. Holcroft, and A.A. Kader Antioxidant activity of pomegranate juice and its relationship with phenolics composition and processing J Agric Food Chem 10 2000 4581 4589
    • (2000) J Agric Food Chem , vol.10 , pp. 4581-4589
    • Gil, M.L.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 44
    • 84910110212 scopus 로고    scopus 로고
    • The insulin resistance syndrome: Impact on lipoprotein metabolism and atherothrombosis
    • H.N. Ginsberg, and L.S. Huang The insulin resistance syndrome: impact on lipoprotein metabolism and atherothrombosis J Cardiovasc Risk 7 2000 325 331
    • (2000) J Cardiovasc Risk , vol.7 , pp. 325-331
    • Ginsberg, H.N.1    Huang, L.S.2
  • 45
    • 0031775498 scopus 로고    scopus 로고
    • Genotype-specific transcriptional regulation of PAI-1 gene by insulin, hypertriglyceridemic VLDL, and Lp(a) in transfected, cultured human endothelial cells
    • H.E. Grenett, R.L. Benza, G.M. Fless, X.N. Li, G.C. Davis, and F.M. Booyse Genotype-specific transcriptional regulation of PAI-1 gene by insulin, hypertriglyceridemic VLDL, and Lp(a) in transfected, cultured human endothelial cells Arterioscler Thromb Vasc Biol 18 1998 1803 1809
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1803-1809
    • Grenett, H.E.1    Benza, R.L.2    Fless, G.M.3    Li, X.N.4    Davis, G.C.5    Booyse, F.M.6
  • 46
    • 0028102993 scopus 로고
    • Effect of diabetes, insulin and glucose load on lipid peroxidation in the rat
    • M.P. Habib, F.D. Dickerson, and A.D. Mooradian Effect of diabetes, insulin and glucose load on lipid peroxidation in the rat Metabolism 43 1994 1442 1445
    • (1994) Metabolism , vol.43 , pp. 1442-1445
    • Habib, M.P.1    Dickerson, F.D.2    Mooradian, A.D.3
  • 47
    • 26244444682 scopus 로고    scopus 로고
    • Macrophage-foam cell formation in streptozotocin-induced diabetic mice: Stimulatory effect of glucose
    • T. Hayek, K. Hussein, M. Aviram, R. Coleman, S. Keidar, and E. Pavoltzky Macrophage-foam cell formation in streptozotocin-induced diabetic mice: Stimulatory effect of glucose Atherosclerosis 183 2005 25 33
    • (2005) Atherosclerosis , vol.183 , pp. 25-33
    • Hayek, T.1    Hussein, K.2    Aviram, M.3    Coleman, R.4    Keidar, S.5    Pavoltzky, E.6
  • 48
    • 36049008500 scopus 로고    scopus 로고
    • Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: A stimulatory role for d-glucose
    • T. Hayek, M. Kaplan, R. Kerry, and M. Aviram Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: a stimulatory role for d-glucose Atherosclerosis 195 2007 277 286
    • (2007) Atherosclerosis , vol.195 , pp. 277-286
    • Hayek, T.1    Kaplan, M.2    Kerry, R.3    Aviram, M.4
  • 49
    • 80051669138 scopus 로고    scopus 로고
    • Oxidative stress and the etiology of insulin resistance and type 2 diabetes
    • E.J. Henriksen, M.K. Diamond-Stanic, and E.M. Marchionne Oxidative stress and the etiology of insulin resistance and type 2 diabetes Free Radic Biol Med 51 2011 993 999
    • (2011) Free Radic Biol Med , vol.51 , pp. 993-999
    • Henriksen, E.J.1    Diamond-Stanic, M.K.2    Marchionne, E.M.3
  • 50
    • 0033964671 scopus 로고    scopus 로고
    • Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells
    • C. Hermann, B. Assmus, C. Urbich, A.M. Zeiher, and S. Dimmeler Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells Arterioscler Thromb Vasc Biol 20 2000 402 409
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 402-409
    • Hermann, C.1    Assmus, B.2    Urbich, C.3    Zeiher, A.M.4    Dimmeler, S.5
  • 51
    • 0033538671 scopus 로고    scopus 로고
    • Expression of human scavenger receptor class B type i in cultured human monocyte-derived macrophages and atherosclerotic lesions
    • K.S. Hirano, Y. Yamashita, T. Nakagawa, F. Ohya, K. Matsuura, and Tsukamoto Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions Circ Res 85 1999 108 116
    • (1999) Circ Res , vol.85 , pp. 108-116
    • Hirano, K.S.1    Yamashita, Y.2    Nakagawa, T.3    Ohya, F.4    Matsuura, K.5    Tsukamoto6
  • 52
  • 53
    • 0032104180 scopus 로고    scopus 로고
    • Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2
    • J.D. Horton, I. Shimomura, and M.S. Brown Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2 J Clin Invest 101 1998 2331 2339
    • (1998) J Clin Invest , vol.101 , pp. 2331-2339
    • Horton, J.D.1    Shimomura, I.2    Brown, M.S.3
  • 54
    • 33646867218 scopus 로고    scopus 로고
    • Roles of ATP binding cassette transporters A1 and G1 scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages
    • W. Jessup, I.C. Gelissen, K. Gaus, and L. Kritharides Roles of ATP binding cassette transporters A1 and G1 scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages Curr Opin Lipidol 17 2006 247 257
    • (2006) Curr Opin Lipidol , vol.17 , pp. 247-257
    • Jessup, W.1    Gelissen, I.C.2    Gaus, K.3    Kritharides, L.4
  • 55
    • 0032880816 scopus 로고    scopus 로고
    • Ox-LDL atherogenic and proinflammatory characteristics during macrophage foam cell formation: An inhibitory role for nutritional antioxidants and serum paraoxonase
    • M. Kaplan, and M. Aviram Ox-LDL atherogenic and proinflammatory characteristics during macrophage foam cell formation: An inhibitory role for nutritional antioxidants and serum paraoxonase Clin Chem Lab Med 37 1999 777 787
    • (1999) Clin Chem Lab Med , vol.37 , pp. 777-787
    • Kaplan, M.1    Aviram, M.2
  • 56
    • 58149354540 scopus 로고    scopus 로고
    • High glucose concentration increases macrophage cholesterol biosynthesis in diabetes through activation of the sterol regulatory element binding protein 1 (SREBP1): Inhibitory effect of insulin
    • M. Kaplan, R. Kerry, M. Aviram, and T. Hayek High glucose concentration increases macrophage cholesterol biosynthesis in diabetes through activation of the sterol regulatory element binding protein 1 (SREBP1): Inhibitory effect of insulin J Cardiovasc Pharmacol 52 2008 324 332
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 324-332
    • Kaplan, M.1    Kerry, R.2    Aviram, M.3    Hayek, T.4
  • 57
    • 84860417839 scopus 로고    scopus 로고
    • Antiatheromatic effects of insulin
    • D.T. Karamitsos Antiatheromatic effects of insulin Diabetes Res Clin Pract 93 Suppl. 1 2011 S105 S108
    • (2011) Diabetes Res Clin Pract , vol.93 , Issue.SUPPL. 1
    • Karamitsos, D.T.1
  • 58
    • 0041823628 scopus 로고    scopus 로고
    • Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
    • H.M. Knott, B.E. Brown, M.J. Davies, and R.T. Dean Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles Eur J Biochem 270 2003 3572 3582
    • (2003) Eur J Biochem , vol.270 , pp. 3572-3582
    • Knott, H.M.1    Brown, B.E.2    Davies, M.J.3    Dean, R.T.4
  • 59
    • 0141526100 scopus 로고    scopus 로고
    • Insulin treatment prevents LDL from accelerated oxidation in patients with diabetes
    • A. Kondo, M. Manabe, K. Saito, M. Maekawa, and T. Kanno Insulin treatment prevents LDL from accelerated oxidation in patients with diabetes J Atheroscler Thromb 9 2002 280 287
    • (2002) J Atheroscler Thromb , vol.9 , pp. 280-287
    • Kondo, A.1    Manabe, M.2    Saito, K.3    Maekawa, M.4    Kanno, T.5
  • 60
    • 82955195724 scopus 로고    scopus 로고
    • The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates β-cell insulin release
    • M. Koren-Gluzer, M. Aviram, E. Meilin, and T. Hayek The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates β-cell insulin release Atherosclerosis 219 2011 510 518
    • (2011) Atherosclerosis , vol.219 , pp. 510-518
    • Koren-Gluzer, M.1    Aviram, M.2    Meilin, E.3    Hayek, T.4
  • 61
    • 0032881850 scopus 로고    scopus 로고
    • Charting the fate of the good cholesterol: Identification and characterization of the high-density lipoprotein receptor SR-BI
    • M. Krieger Charting the fate of the good cholesterol: Identification and characterization of the high-density lipoprotein receptor SR-BI Annu Rev Biochem 68 1999 523 558
    • (1999) Annu Rev Biochem , vol.68 , pp. 523-558
    • Krieger, M.1
  • 62
    • 0026572097 scopus 로고
    • 2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase
    • 2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase J Clin Invest 89 1992 1006 1013
    • (1992) J Clin Invest , vol.89 , pp. 1006-1013
    • Krieger-Brauer, H.1    Kather, H.2
  • 63
    • 0034651949 scopus 로고    scopus 로고
    • Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin
    • K. Kuboki, Z.Y. Jiang, N. Takahara, S.W. Ha, M. Igarashi, and T. Yamauchi Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin Circulation 101 2000 676 681
    • (2000) Circulation , vol.101 , pp. 676-681
    • Kuboki, K.1    Jiang, Z.Y.2    Takahara, N.3    Ha, S.W.4    Igarashi, M.5    Yamauchi, T.6
  • 65
    • 85047690709 scopus 로고    scopus 로고
    • Increased CD36 protein as a response to defective insulin signaling in macrophages
    • C.P. Liang, S. Han, R.C. Okamoto, I. Tabas, D. Accili, and A.R. Tall Increased CD36 protein as a response to defective insulin signaling in macrophages J Clin Invest 113 2004 764 773
    • (2004) J Clin Invest , vol.113 , pp. 764-773
    • Liang, C.P.1    Han, S.2    Okamoto, R.C.3    Tabas, I.4    Accili, D.5    Tall, A.R.6
  • 66
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • A.J. Lusis Atherosclerosis Nature 407 2000 233 241
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 67
    • 25444464894 scopus 로고    scopus 로고
    • The paraoxonase-2-310 polymorphism is associated with the presence of microvascular complications in diabetes mellitus
    • B. Mackness, P. McElduff, and M.I. Mackness The paraoxonase-2-310 polymorphism is associated with the presence of microvascular complications in diabetes mellitus J Intern Med 258 2005 363 368
    • (2005) J Intern Med , vol.258 , pp. 363-368
    • MacKness, B.1    McElduff, P.2    MacKness, M.I.3
  • 68
    • 1842844426 scopus 로고    scopus 로고
    • Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase
    • R. Madonna, A. Pandolfi, M. Massaro, A. Consoli, and R. De Caterina Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase Diabetologia 47 2004 532 536
    • (2004) Diabetologia , vol.47 , pp. 532-536
    • Madonna, R.1    Pandolfi, A.2    Massaro, M.3    Consoli, A.4    De Caterina, R.5
  • 70
    • 0038359684 scopus 로고    scopus 로고
    • Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications
    • P. Martin-Gallan, A. Carrascosa, M. Gussinye, and C. Dominguez Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications Free Radic Biol Med 34 2003 1563 1574
    • (2003) Free Radic Biol Med , vol.34 , pp. 1563-1574
    • Martin-Gallan, P.1    Carrascosa, A.2    Gussinye, M.3    Dominguez, C.4
  • 71
    • 33845530202 scopus 로고    scopus 로고
    • Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes
    • M. Mastorikou, M. Mackness, and B. Mackness Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes Diabetes 55 2006 3099 3103
    • (2006) Diabetes , vol.55 , pp. 3099-3103
    • Mastorikou, M.1    MacKness, M.2    MacKness, B.3
  • 72
    • 50649095436 scopus 로고    scopus 로고
    • Glycation of paraoxonase 1 inhibits its activity and impairs the ability of high-density lipoprotein to metabolize membrane lipid hydroperoxides
    • M. Mastorikou, B. Mackness, Y. Liu, and M. Mackness Glycation of paraoxonase 1 inhibits its activity and impairs the ability of high-density lipoprotein to metabolize membrane lipid hydroperoxides Diabet Med 25 2008 1049 1055
    • (2008) Diabet Med , vol.25 , pp. 1049-1055
    • Mastorikou, M.1    MacKness, B.2    Liu, Y.3    MacKness, M.4
  • 73
    • 78650232469 scopus 로고    scopus 로고
    • Banting Memorial Lecture 2010. Type 2 diabetes as an 'infectious' disease: Is this the Black Death of the 21st century?
    • D.R. Matthews, and P.C. Matthews Banting Memorial Lecture 2010. Type 2 diabetes as an 'infectious' disease: Is this the Black Death of the 21st century? Diabet Med 28 1 2011 2 9
    • (2011) Diabet Med , vol.28 , Issue.1 , pp. 2-9
    • Matthews, D.R.1    Matthews, P.C.2
  • 74
    • 0028943670 scopus 로고
    • Glucose-enriched medium enhances cell-mediated low density lipoprotein peroxidation
    • C. Maziere, M. Auclair, F. Rose-Robert, P. Leflon, and J.C. Maziere Glucose-enriched medium enhances cell-mediated low density lipoprotein peroxidation FEBS Lett 363 1995 277 279
    • (1995) FEBS Lett , vol.363 , pp. 277-279
    • Maziere, C.1    Auclair, M.2    Rose-Robert, F.3    Leflon, P.4    Maziere, J.C.5
  • 75
    • 0021367111 scopus 로고
    • In vivo stimulation of low-density lipoprotein degradation by insulin
    • T. Mazzone, D. Foster, and A. Chait In vivo stimulation of low-density lipoprotein degradation by insulin Diabetes 33 1984 333 338
    • (1984) Diabetes , vol.33 , pp. 333-338
    • Mazzone, T.1    Foster, D.2    Chait, A.3
  • 76
    • 75049083347 scopus 로고    scopus 로고
    • Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: Studies in PON2-deficient mice
    • E. Meilin, M. Aviram, and T. Hayek Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: Studies in PON2-deficient mice Atherosclerosis 208 2010 390 395
    • (2010) Atherosclerosis , vol.208 , pp. 390-395
    • Meilin, E.1    Aviram, M.2    Hayek, T.3
  • 77
    • 79954613936 scopus 로고    scopus 로고
    • Insulin increases macrophage triglyceride accumulation under diabetic conditions through the down regulation of hormone sensitive lipase and adipose triglyceride lipase
    • E. Meilin, M. Aviram, and T. Hayek Insulin increases macrophage triglyceride accumulation under diabetic conditions through the down regulation of hormone sensitive lipase and adipose triglyceride lipase Biofactors 37 2011 95 103
    • (2011) Biofactors , vol.37 , pp. 95-103
    • Meilin, E.1    Aviram, M.2    Hayek, T.3
  • 78
  • 79
    • 39749147110 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
    • D.M. Muoio, and C.B. Newgard Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes Nat Rev Mol Cell Biol 9 2008 193 205
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 193-205
    • Muoio, D.M.1    Newgard, C.B.2
  • 80
    • 79955911852 scopus 로고    scopus 로고
    • Vasculotoxic effects of insulin and its role in atherosclerosis: What is the evidence?
    • S. Nandish, O. Bailon, J. Wyatt, J. Smith, A. Stevens, and M. Lujan Vasculotoxic effects of insulin and its role in atherosclerosis: What is the evidence? Curr Atheroscler Rep 13 2011 123 128
    • (2011) Curr Atheroscler Rep , vol.13 , pp. 123-128
    • Nandish, S.1    Bailon, O.2    Wyatt, J.3    Smith, J.4    Stevens, A.5    Lujan, M.6
  • 82
    • 0037157596 scopus 로고    scopus 로고
    • Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: A prospective study
    • A. Norhammar, A. Tenerz, G. Nilsson, A. Hamsten, S. Efendíc, and L. Rydén Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: A prospective study Lancet 359 2002 2140 2144
    • (2002) Lancet , vol.359 , pp. 2140-2144
    • Norhammar, A.1    Tenerz, A.2    Nilsson, G.3    Hamsten, A.4    Efendíc, S.5    Rydén, L.6
  • 83
    • 0038343487 scopus 로고    scopus 로고
    • Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: A new crossroad of AGE to cholesterol metabolism
    • N. Ohgami, A. Miyazaki, M. Sakai, A. Kuniyasu, H. Nakayama, and S. Horiuchi Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: A new crossroad of AGE to cholesterol metabolism J Atheroscler Thromb 10 2003 1 6
    • (2003) J Atheroscler Thromb , vol.10 , pp. 1-6
    • Ohgami, N.1    Miyazaki, A.2    Sakai, M.3    Kuniyasu, A.4    Nakayama, H.5    Horiuchi, S.6
  • 84
    • 34848815430 scopus 로고    scopus 로고
    • Changes in glycaemic control and risk of coronary artery disease in type 1 diabetes mellitus: Findings from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC)
    • C.T. Prince, D.J. Becker, T. Costacou, R.G. Miller, and T.J. Orchard Changes in glycaemic control and risk of coronary artery disease in type 1 diabetes mellitus: Findings from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) Diabetologia 50 2007 2280 2288
    • (2007) Diabetologia , vol.50 , pp. 2280-2288
    • Prince, C.T.1    Becker, D.J.2    Costacou, T.3    Miller, R.G.4    Orchard, T.J.5
  • 87
    • 79551470306 scopus 로고    scopus 로고
    • Oxidative stress, insulin signaling, and diabetes
    • J.L. Rains, and S.K. Jain Oxidative stress, insulin signaling, and diabetes Free Radic Biol Med 50 2011 567 575
    • (2011) Free Radic Biol Med , vol.50 , pp. 567-575
    • Rains, J.L.1    Jain, S.K.2
  • 88
    • 77955292064 scopus 로고    scopus 로고
    • Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein e null mice
    • C. Rask-Madsen, Q. Li, B. Freund, D. Feather, R. Abramov, and I.H. Wu Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice Cell Metab 11 5 2010 379 389
    • (2010) Cell Metab , vol.11 , Issue.5 , pp. 379-389
    • Rask-Madsen, C.1    Li, Q.2    Freund, B.3    Feather, D.4    Abramov, R.5    Wu, I.H.6
  • 89
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • G.M. Reaven Role of insulin resistance in human disease Diabetes 37 1988 1595 1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 90
    • 0034128280 scopus 로고    scopus 로고
    • Triglyceride synthesis: Insights from the cloning of diacylglycerol acyltransferase
    • V. Robert, Jr Farese, C. Sylvaine, and S.J. Smith Triglyceride synthesis: Insights from the cloning of diacylglycerol acyltransferase Curr Opin Lipidol 11 2000 229 234
    • (2000) Curr Opin Lipidol , vol.11 , pp. 229-234
    • Robert, V.1    Farese, J.2    Sylvaine, C.3    Smith, S.J.4
  • 91
    • 0030812762 scopus 로고    scopus 로고
    • Insulin and sulfonylurea therapy in NIDDM patients. Are the effects on lipoprotein metabolism different even with similar blood glucose control?
    • G. Romano, L. Patt,i, F. Innelli, L. Di Marino, G. Annuzzi, and M. Iavicoli Insulin and sulfonylurea therapy in NIDDM patients. Are the effects on lipoprotein metabolism different even with similar blood glucose control? Diabetes 46 1997 1601 1606
    • (1997) Diabetes , vol.46 , pp. 1601-1606
    • Romano, G.1    Patt, I.L.2    Innelli, F.3    Di Marino, L.4    Annuzzi, G.5    Iavicoli, M.6
  • 92
    • 65549138006 scopus 로고    scopus 로고
    • Paraoxonases role in the prevention of cardiovascular diseases
    • M. Rosenblat, and M. Aviram Paraoxonases role in the prevention of cardiovascular diseases Biofactors 35 2009 98 104
    • (2009) Biofactors , vol.35 , pp. 98-104
    • Rosenblat, M.1    Aviram, M.2
  • 93
    • 67649690455 scopus 로고    scopus 로고
    • Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1 (DGAT1), the rate limiting enzyme in triglyceride biosynthesis
    • M. Rosenblat, R. Coleman, S.T. Reddy, and M. Aviram Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1 (DGAT1), the rate limiting enzyme in triglyceride biosynthesis J Lipid Res 50 2009 870 879
    • (2009) J Lipid Res , vol.50 , pp. 870-879
    • Rosenblat, M.1    Coleman, R.2    Reddy, S.T.3    Aviram, M.4
  • 94
    • 33745495836 scopus 로고    scopus 로고
    • Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages
    • M. Rosenblat, T. Hayek, and M. Aviram Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages Atherosclerosis 187 2006 363 371
    • (2006) Atherosclerosis , vol.187 , pp. 363-371
    • Rosenblat, M.1    Hayek, T.2    Aviram, M.3
  • 95
    • 33744511920 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: Relevance to diabetes
    • M. Rosenblat, R. Karry, and M. Aviram Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: Relevance to diabetes Atherosclerosis 187 2006 74 81
    • (2006) Atherosclerosis , vol.187 , pp. 74-81
    • Rosenblat, M.1    Karry, R.2    Aviram, M.3
  • 96
    • 43049162677 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties
    • O. Rozenberg, M. Shiner, M. Aviram, and T. Hayek Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties Free Radic Biol Med 44 2008 1951 1959
    • (2008) Free Radic Biol Med , vol.44 , pp. 1951-1959
    • Rozenberg, O.1    Shiner, M.2    Aviram, M.3    Hayek, T.4
  • 97
    • 0032570590 scopus 로고    scopus 로고
    • The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells
    • S. Rustaeus, P. Stillemark, K. Lindberg, D. Gordon, and S.V. Olofsson The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells J Biol Chem 273 1998 5196 5203
    • (1998) J Biol Chem , vol.273 , pp. 5196-5203
    • Rustaeus, S.1    Stillemark, P.2    Lindberg, K.3    Gordon, D.4    Olofsson, S.V.5
  • 98
    • 33846029180 scopus 로고    scopus 로고
    • Adipose triglyceride lipase and hormone sensitive lipase are the major enzymes in adipose triacylglycerol catabolism
    • M. Schwiger, R. Schreiber, G. Haemmerle, A. Lass, C. Fledelius, and P. Jacobsen Adipose triglyceride lipase and hormone sensitive lipase are the major enzymes in adipose triacylglycerol catabolism J Biol Chem 281 2006 40236 40241
    • (2006) J Biol Chem , vol.281 , pp. 40236-40241
    • Schwiger, M.1    Schreiber, R.2    Haemmerle, G.3    Lass, A.4    Fledelius, C.5    Jacobsen, P.6
  • 100
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins transcriptional regulators of lipid synthetic genes
    • H. Shimano Sterol regulatory element binding proteins transcriptional regulators of lipid synthetic genes Prog Lipid Res 40 2001 439 452
    • (2001) Prog Lipid Res , vol.40 , pp. 439-452
    • Shimano, H.1
  • 101
    • 0030031585 scopus 로고    scopus 로고
    • Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: Studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes
    • D. Sparks, T.L. Phung, M. Bolognino, and C.E. Sparks Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: Studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes Biochem J 313 1996 567 574
    • (1996) Biochem J , vol.313 , pp. 567-574
    • Sparks, D.1    Phung, T.L.2    Bolognino, M.3    Sparks, C.E.4
  • 103
    • 0028030813 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
    • H.O. Steinberg, G. Brechtel, A. Johnson, N. Fineberg, and A.D. Baron Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release J Clin Invest 94 1994 1172 1179
    • (1994) J Clin Invest , vol.94 , pp. 1172-1179
    • Steinberg, H.O.1    Brechtel, G.2    Johnson, A.3    Fineberg, N.4    Baron, A.D.5
  • 104
    • 0029886687 scopus 로고    scopus 로고
    • Hyperinsulinemia and atherosclerosis
    • R.W. Stout Hyperinsulinemia and atherosclerosis Diabetes 45 Suppl. 3 1996 S45 S46
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 3
    • Stout, R.W.1
  • 105
    • 78650943619 scopus 로고    scopus 로고
    • Effects of vitamin e supplementation on glycaemic control in type 2 diabetes: Systematic review of randomized controlled trials
    • N. Suksomboon, N. Poolsup, and S. Sinprasert Effects of vitamin E supplementation on glycaemic control in type 2 diabetes: Systematic review of randomized controlled trials J Clin Pharm Ther 36 2011 53 63
    • (2011) J Clin Pharm Ther , vol.36 , pp. 53-63
    • Suksomboon, N.1    Poolsup, N.2    Sinprasert, S.3
  • 106
    • 38849114338 scopus 로고    scopus 로고
    • Cholesterol efflux pathways and other potential mechanisms involved in the atheroprotective effect of high density lipoprotein
    • A.R. Tall Cholesterol efflux pathways and other potential mechanisms involved in the atheroprotective effect of high density lipoprotein J Intern Med 263 2008 256 273
    • (2008) J Intern Med , vol.263 , pp. 256-273
    • Tall, A.R.1
  • 107
    • 77954509575 scopus 로고    scopus 로고
    • Atherosclerosis, diabetes and lipoproteins
    • G.H. Tomkin Atherosclerosis, diabetes and lipoproteins Expert Rev Cardiovasc Ther 8 2010 1015 1029
    • (2010) Expert Rev Cardiovasc Ther , vol.8 , pp. 1015-1029
    • Tomkin, G.H.1
  • 108
    • 20544469710 scopus 로고    scopus 로고
    • Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis
    • M. Van Eck, M. Pennings, M. Hoekstra, R. Out, and T.J. Van Berkel Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis Curr Opin Lipidol 16 2005 307 315
    • (2005) Curr Opin Lipidol , vol.16 , pp. 307-315
    • Van Eck, M.1    Pennings, M.2    Hoekstra, M.3    Out, R.4    Van Berkel, T.J.5
  • 109
    • 0036787465 scopus 로고    scopus 로고
    • Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha
    • S.K. Venugopal, S. Devaraj, T. Yang, and I. Jialal Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha Diabetes 51 2002 3049 3054
    • (2002) Diabetes , vol.51 , pp. 3049-3054
    • Venugopal, S.K.1    Devaraj, S.2    Yang, T.3    Jialal, I.4
  • 110
    • 24644491335 scopus 로고    scopus 로고
    • Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice
    • R.K. Vikramadithyan, Y. Hu, H.L. Noh, C.P. Liang, K. Hallam, and A.R. Tall Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice J Clin Invest 2005 2005 2434 2443
    • (2005) J Clin Invest , vol.2005 , pp. 2434-2443
    • Vikramadithyan, R.K.1    Hu, Y.2    Noh, H.L.3    Liang, C.P.4    Hallam, K.5    Tall, A.R.6
  • 111
    • 78751640180 scopus 로고    scopus 로고
    • Possible contributions of lipoproteins and cholesterol to the pathogenesis of diabetes mellitus type 2
    • A. Von Eckardstein, and R.A. Sibler Possible contributions of lipoproteins and cholesterol to the pathogenesis of diabetes mellitus type 2 Curr Opin Lipidol 22 2011 26 32
    • (2011) Curr Opin Lipidol , vol.22 , pp. 26-32
    • Von Eckardstein, A.1    Sibler, R.A.2
  • 112
    • 0028811449 scopus 로고
    • The Insulin Resistance Atherosclerosis Study (IRAS) objectives, design, and recruitment results
    • L.E. Wagenknecht, E.J. Mayer, M. Rewers, S. Haffner, J. Selby, and G.M. Borok The Insulin Resistance Atherosclerosis Study (IRAS) objectives, design, and recruitment results Ann Epidemiol 5 1995 464 472
    • (1995) Ann Epidemiol , vol.5 , pp. 464-472
    • Wagenknecht, L.E.1    Mayer, E.J.2    Rewers, M.3    Haffner, S.4    Selby, J.5    Borok, G.M.6
  • 113
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
    • G. Zeng, and M.J. Quon Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells J Clin Invest 98 1996 894 898
    • (1996) J Clin Invest , vol.98 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 114
    • 60849115896 scopus 로고    scopus 로고
    • Cellular cholesterol efflux to serum is 399 impaired in diabetic nephropathy
    • H. Zhou, K.C. Tan, S.W. Shiu, and Y. Wong Cellular cholesterol efflux to serum is 399 impaired in diabetic nephropathy Diabetes Metab Res Rev 24 2008 617 623
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 617-623
    • Zhou, H.1    Tan, K.C.2    Shiu, S.W.3    Wong, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.