메뉴 건너뛰기




Volumn 187, Issue 2, 2006, Pages 363-371

Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages

Author keywords

Atherosclerosis; Diabetes; Macrophages; Oxidative stress; Pomegranate juice

Indexed keywords

ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE; CHOLESTEROL; GLUCOSE; GLUTATHIONE; LIPID PEROXIDE; SUGAR; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL;

EID: 33745495836     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2005.09.006     Document Type: Article
Times cited : (288)

References (48)
  • 1
    • 18644377022 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory cardiovascular disorder
    • Ziegler D. Type 2 diabetes as an inflammatory cardiovascular disorder. Curr Mol Med 5 (2005) 309-322
    • (2005) Curr Mol Med , vol.5 , pp. 309-322
    • Ziegler, D.1
  • 2
    • 23044498556 scopus 로고    scopus 로고
    • Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study
    • Wattanakit K., Folsom A.R., Selvin E., et al. Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis 180 (2005) 389-397
    • (2005) Atherosclerosis , vol.180 , pp. 389-397
    • Wattanakit, K.1    Folsom, A.R.2    Selvin, E.3
  • 3
    • 1642616527 scopus 로고    scopus 로고
    • How hyperglycemia promotes atherosclerosis: molecular mechanisms
    • Aronson D., and Rayfield E.J. How hyperglycemia promotes atherosclerosis: molecular mechanisms. Cardiovasc Diabetol 1 (2002) 1
    • (2002) Cardiovasc Diabetol , vol.1 , pp. 1
    • Aronson, D.1    Rayfield, E.J.2
  • 4
    • 2442421194 scopus 로고    scopus 로고
    • Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited
    • Ceriello A., and Motz E. Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol 24 (2004) 816-823
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 816-823
    • Ceriello, A.1    Motz, E.2
  • 5
    • 0038359684 scopus 로고    scopus 로고
    • Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications
    • Martin-Gallan P., Carrascosa A., Gussinye M., and Dominguez C. Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications. Free Radic Biol Med 34 (2003) 1563-1574
    • (2003) Free Radic Biol Med , vol.34 , pp. 1563-1574
    • Martin-Gallan, P.1    Carrascosa, A.2    Gussinye, M.3    Dominguez, C.4
  • 6
    • 20444380690 scopus 로고    scopus 로고
    • Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species
    • Whiteside C.L. Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species. Curr Hypertens Rep 7 (2005) 148-154
    • (2005) Curr Hypertens Rep , vol.7 , pp. 148-154
    • Whiteside, C.L.1
  • 7
    • 26844564082 scopus 로고    scopus 로고
    • Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice
    • Johansen J.S., Harris A.K., Rychly D.J., and Ergul A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 4 (2005) 5
    • (2005) Cardiovasc Diabetol , vol.4 , pp. 5
    • Johansen, J.S.1    Harris, A.K.2    Rychly, D.J.3    Ergul, A.4
  • 8
    • 0036196952 scopus 로고    scopus 로고
    • Effects of alpha-tocopherol supplementation and continuous subcutaneous insulin infusion on oxidative stress in Korean patients with type 2 diabetes
    • Park S., and Choi S.B. Effects of alpha-tocopherol supplementation and continuous subcutaneous insulin infusion on oxidative stress in Korean patients with type 2 diabetes. Am J Clin Nutr 75 (2002) 728-733
    • (2002) Am J Clin Nutr , vol.75 , pp. 728-733
    • Park, S.1    Choi, S.B.2
  • 9
    • 0035062055 scopus 로고    scopus 로고
    • Red wine protects diabetic patients from metal-induced oxidative stress and thrombosis: a pleasant approach to the prevention of cardiovascular disease in diabetes
    • Ceriello A., Bortolotti N., Motz E., et al. Red wine protects diabetic patients from metal-induced oxidative stress and thrombosis: a pleasant approach to the prevention of cardiovascular disease in diabetes. Eur J Clin Invest 31 (2001) 322-328
    • (2001) Eur J Clin Invest , vol.31 , pp. 322-328
    • Ceriello, A.1    Bortolotti, N.2    Motz, E.3
  • 10
    • 14644414751 scopus 로고    scopus 로고
    • Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes
    • Rizvi S.I., Zaid M.A., Anis R., and Mishra N. Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes. Clin Exp Pharmacol Physiol 32 (2005) 70-75
    • (2005) Clin Exp Pharmacol Physiol , vol.32 , pp. 70-75
    • Rizvi, S.I.1    Zaid, M.A.2    Anis, R.3    Mishra, N.4
  • 11
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolics composition and processing
    • Gil M.L., Tomas-Barberan F.A., Hess-Pierce B., Holcroft D.M., and Kader A.A. Antioxidant activity of pomegranate juice and its relationship with phenolics composition and processing. J Agric Food Chem 10 (2000) 4581-4589
    • (2000) J Agric Food Chem , vol.10 , pp. 4581-4589
    • Gil, M.L.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 12
    • 33745506681 scopus 로고    scopus 로고
    • Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. In: Pasquier C, editor. Proceedings of the XI Biennial Meeting of the Society for Free Radical Research International. Paris, France, 16-20 July, 2002. Monduzzi Editore S.P, A-MEDIMOND Inc., pp. 523-28.
  • 13
    • 0034013311 scopus 로고    scopus 로고
    • Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice
    • Aviram M., Dornfeld L., Rosenblat M., et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr 71 (2000) 1062-1076
    • (2000) Am J Clin Nutr , vol.71 , pp. 1062-1076
    • Aviram, M.1    Dornfeld, L.2    Rosenblat, M.3
  • 14
    • 3042653405 scopus 로고    scopus 로고
    • Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation
    • Aviram M., Rosenblat M., Gaitini D., et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 23 (2004) 423-433
    • (2004) Clin Nutr , vol.23 , pp. 423-433
    • Aviram, M.1    Rosenblat, M.2    Gaitini, D.3
  • 15
    • 11844262719 scopus 로고    scopus 로고
    • Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture
    • Boyle J.J. Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol 3 (2005) 63-68
    • (2005) Curr Vasc Pharmacol , vol.3 , pp. 63-68
    • Boyle, J.J.1
  • 17
    • 0033784947 scopus 로고    scopus 로고
    • Diabetic state induces lipid loading and altered expression and secretion of lipoprotein lipase in human monocytes-derived macrophages
    • Dobrian A.D., Lazar V., Sinescu C., Mincu D., and Simionescu M. Diabetic state induces lipid loading and altered expression and secretion of lipoprotein lipase in human monocytes-derived macrophages. Atherosclerosis 153 (2000) 191-201
    • (2000) Atherosclerosis , vol.153 , pp. 191-201
    • Dobrian, A.D.1    Lazar, V.2    Sinescu, C.3    Mincu, D.4    Simionescu, M.5
  • 18
    • 0345346385 scopus 로고    scopus 로고
    • Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo
    • Ceolotto G., Gallo A., Miola M., et al. Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo. Diabetes 48 (1999) 1316-1322
    • (1999) Diabetes , vol.48 , pp. 1316-1322
    • Ceolotto, G.1    Gallo, A.2    Miola, M.3
  • 19
    • 1842830425 scopus 로고    scopus 로고
    • Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation
    • Ling Li, Tatsuya S., and Genevieve R. Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation. Circ Res 94 (2004) 892-901
    • (2004) Circ Res , vol.94 , pp. 892-901
    • Ling Li1    Tatsuya, S.2    Genevieve, R.3
  • 20
    • 13544273816 scopus 로고    scopus 로고
    • Expression of class A scavenger receptor is enhanced by high glucose in vitro under diabetic conditions in vivo: one mechanism for an increased rate of atherosclerosis in diabetes
    • Fukuhara-Takaki K., Sakai M., Sakamoto Y., Takeya M., and Horiuchi S. Expression of class A scavenger receptor is enhanced by high glucose in vitro under diabetic conditions in vivo: one mechanism for an increased rate of atherosclerosis in diabetes. J Biol Chem 280 (2005) 3355-3364
    • (2005) J Biol Chem , vol.280 , pp. 3355-3364
    • Fukuhara-Takaki, K.1    Sakai, M.2    Sakamoto, Y.3    Takeya, M.4    Horiuchi, S.5
  • 21
    • 33745511775 scopus 로고    scopus 로고
    • Hayek T, Hussein K, Aviram M, et al. Macrophage foam cell formation in streptozotocin-induced diabetic mice: stimulatory effect of glucose. Atherosclerosis, in press.
  • 22
    • 0026096803 scopus 로고
    • Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities
    • Gan K.N., Smolen A., Eckerson H.W., and La D.B.N. Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities. Drug Metab Dispos 19 (1991) 100-106
    • (1991) Drug Metab Dispos , vol.19 , pp. 100-106
    • Gan, K.N.1    Smolen, A.2    Eckerson, H.W.3    La, D.B.N.4
  • 23
    • 0024239038 scopus 로고
    • Antioxidant defenses and lipid peroxidation in human blood plasma
    • Frei B., Stocker R., and Ames B.N. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci USA 85 (1988) 9748-9752
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9748-9752
    • Frei, B.1    Stocker, R.2    Ames, B.N.3
  • 24
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol 52 (1978) 302-310
    • (1978) Methods Enzymol , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 25
    • 0024584235 scopus 로고
    • Spectrophotometric assay for lipid peroxides in serum lipoproteins using commercially available reagent
    • El-Saadani M., Esterbauer N., El-Sayed M., Goher M., Nassar A.Y., and Jurgens G. Spectrophotometric assay for lipid peroxides in serum lipoproteins using commercially available reagent. J Lipid Res 30 (1989) 627-630
    • (1989) J Lipid Res , vol.30 , pp. 627-630
    • El-Saadani, M.1    Esterbauer, N.2    El-Sayed, M.3    Goher, M.4    Nassar, A.Y.5    Jurgens, G.6
  • 26
    • 0023693038 scopus 로고
    • In vivo effects of aurothioglucose and sodium thioglucose on rat tissue sulfhydryl levels and plasma sulfhydryl reactivity
    • Hu M.-L., Dillard C.J., and Tappel A.I. In vivo effects of aurothioglucose and sodium thioglucose on rat tissue sulfhydryl levels and plasma sulfhydryl reactivity. Agents Actions 25 (1988) 132-138
    • (1988) Agents Actions , vol.25 , pp. 132-138
    • Hu, M.-L.1    Dillard, C.J.2    Tappel, A.I.3
  • 27
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel C.P., Ischiropoulos H., and Bondy S.C. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5 (1992) 227-231
    • (1992) Chem Res Toxicol , vol.5 , pp. 227-231
    • LeBel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 28
    • 0020625894 scopus 로고
    • Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation
    • Bass D.A., Parce J.W., Dechatelet L.R., Szejda P., Seeds M.C., and Thomas M. Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 130 (1983) 1910-1917
    • (1983) J Immunol , vol.130 , pp. 1910-1917
    • Bass, D.A.1    Parce, J.W.2    Dechatelet, L.R.3    Szejda, P.4    Seeds, M.C.5    Thomas, M.6
  • 30
    • 0014481378 scopus 로고
    • Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: application to mammalian blood and other tissues
    • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: application to mammalian blood and other tissues. Anal Biochem 27 (1969) 502-522
    • (1969) Anal Biochem , vol.27 , pp. 502-522
    • Tietze, F.1
  • 31
    • 0020610387 scopus 로고
    • Plasma lipoprotein separation by discontinuous density gradient ultracentrifugation in hyperlipoproteinemic patients
    • Aviram M. Plasma lipoprotein separation by discontinuous density gradient ultracentrifugation in hyperlipoproteinemic patients. Biochem Med 30 (1983) 111-118
    • (1983) Biochem Med , vol.30 , pp. 111-118
    • Aviram, M.1
  • 32
    • 5344238178 scopus 로고    scopus 로고
    • Paraoxonases 1, 2 and 3, oxidative stress and macrophage foam cells formation during atherosclerosis development
    • Aviram M., and Rosenblat M. Paraoxonases 1, 2 and 3, oxidative stress and macrophage foam cells formation during atherosclerosis development. Free Radic Biol Med 37 (2004) 1304-1316
    • (2004) Free Radic Biol Med , vol.37 , pp. 1304-1316
    • Aviram, M.1    Rosenblat, M.2
  • 33
    • 0033230043 scopus 로고    scopus 로고
    • Glutathione and its role in cellular functions
    • Sies H. Glutathione and its role in cellular functions. Free Radic Res 27 (1999) 916-921
    • (1999) Free Radic Res , vol.27 , pp. 916-921
    • Sies, H.1
  • 34
    • 0036123993 scopus 로고    scopus 로고
    • Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized LDL in macrophage from atherosclerotic mice: protective role of antioxidants and paraoxonase
    • Fuhrman B., Volkova N., and Aviram M. Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized LDL in macrophage from atherosclerotic mice: protective role of antioxidants and paraoxonase. Atherosclerosis 161 (2002) 307-316
    • (2002) Atherosclerosis , vol.161 , pp. 307-316
    • Fuhrman, B.1    Volkova, N.2    Aviram, M.3
  • 35
    • 0344034769 scopus 로고    scopus 로고
    • Lipoprotein abnormalities and their consequences for patients with type 2 diabetes
    • Krentz A.J. Lipoprotein abnormalities and their consequences for patients with type 2 diabetes. Diab Obes Metab 5 Suppl. 1 (2003) S19-S27
    • (2003) Diab Obes Metab , vol.5 , Issue.SUPPL. 1
    • Krentz, A.J.1
  • 36
    • 84984526124 scopus 로고
    • Chemical composition of juice and seeds of pomegranate fruit
    • El-Nemr S.E., Ismail I.A., and Ragab M. Chemical composition of juice and seeds of pomegranate fruit. Nahrung 34 (1991) 601-606
    • (1991) Nahrung , vol.34 , pp. 601-606
    • El-Nemr, S.E.1    Ismail, I.A.2    Ragab, M.3
  • 37
    • 17144365092 scopus 로고    scopus 로고
    • Malondialdehyde, glutathione, glutathione peroxidase and homocysteine levels in type 2 diabetic patients with and without microalbuminuria
    • Ozdemir G., Ozden M., Maral H., Kuskay S., Cetinalp P., and Tarkum I. Malondialdehyde, glutathione, glutathione peroxidase and homocysteine levels in type 2 diabetic patients with and without microalbuminuria. Am Clin Biochem 42 (2005) 99-104
    • (2005) Am Clin Biochem , vol.42 , pp. 99-104
    • Ozdemir, G.1    Ozden, M.2    Maral, H.3    Kuskay, S.4    Cetinalp, P.5    Tarkum, I.6
  • 38
    • 0041823628 scopus 로고    scopus 로고
    • Glycation and glycooxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
    • Knott H.M., Brown B.E., Davies M.J., and Dean R.T. Glycation and glycooxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles. Eur J Biochem 270 (2003) 3572-3582
    • (2003) Eur J Biochem , vol.270 , pp. 3572-3582
    • Knott, H.M.1    Brown, B.E.2    Davies, M.J.3    Dean, R.T.4
  • 39
    • 0032877558 scopus 로고    scopus 로고
    • Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may be due to the abnormal composition of HDL
    • Gowri M.S., Van der Westhuyzen D.R., Brodges S.R., and Anderson J.W. Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may be due to the abnormal composition of HDL. Arterioscler Thromb Vasc Biol 19 (1999) 2226-2233
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2226-2233
    • Gowri, M.S.1    Van der Westhuyzen, D.R.2    Brodges, S.R.3    Anderson, J.W.4
  • 40
    • 0036737786 scopus 로고    scopus 로고
    • Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications
    • Letellier C., Duron M.R., Jouanolle A.M., et al. Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications. Diab Metab 28 (2002) 297-304
    • (2002) Diab Metab , vol.28 , pp. 297-304
    • Letellier, C.1    Duron, M.R.2    Jouanolle, A.M.3
  • 41
    • 1842454052 scopus 로고    scopus 로고
    • Correlation of plasma oxidized low-density lipoprotein levels to vascular complications and human serum paraoxonase in patients with type 2 diabetes
    • Tsuzura S., Ikeda Y., Suchiro T., et al. Correlation of plasma oxidized low-density lipoprotein levels to vascular complications and human serum paraoxonase in patients with type 2 diabetes. Metabolism 53 (2004) 297-302
    • (2004) Metabolism , vol.53 , pp. 297-302
    • Tsuzura, S.1    Ikeda, Y.2    Suchiro, T.3
  • 42
    • 0032921557 scopus 로고    scopus 로고
    • Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants
    • Aviram M., Rosenblat M., Billecke S., et al. Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med 26 (1999) 892-904
    • (1999) Free Radic Biol Med , vol.26 , pp. 892-904
    • Aviram, M.1    Rosenblat, M.2    Billecke, S.3
  • 43
    • 0035710008 scopus 로고    scopus 로고
    • Effect of glycation of high density lipoproteins on their physiochemical properties and on paraoxonase activity
    • Ferretti G., Bacchetti T., Marchionni C., et al. Effect of glycation of high density lipoproteins on their physiochemical properties and on paraoxonase activity. Acta Diabetol 38 (2001) 163-169
    • (2001) Acta Diabetol , vol.38 , pp. 163-169
    • Ferretti, G.1    Bacchetti, T.2    Marchionni, C.3
  • 44
    • 20444419056 scopus 로고    scopus 로고
    • Paraoxonase (1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice
    • Rozenberg O., Shih D.M., and Aviram M. Paraoxonase (1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice. Atherosclerosis 181 (2005) 9-18
    • (2005) Atherosclerosis , vol.181 , pp. 9-18
    • Rozenberg, O.1    Shih, D.M.2    Aviram, M.3
  • 45
    • 23944519922 scopus 로고    scopus 로고
    • Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages
    • Fuhrman B., Volkova N., and Aviram M. Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages. Atherosclerosis 16 (2005) 570-576
    • (2005) Atherosclerosis , vol.16 , pp. 570-576
    • Fuhrman, B.1    Volkova, N.2    Aviram, M.3
  • 46
    • 0037369679 scopus 로고    scopus 로고
    • Increased expression of scavenger receptor (CD36) in monocytes from subjects with type 2 diabetes
    • Sampson M.J., Davies I.R., Braschi S., Ivory K., and Hughes D.A. Increased expression of scavenger receptor (CD36) in monocytes from subjects with type 2 diabetes. Atherosclerosis 167 (2003) 120-134
    • (2003) Atherosclerosis , vol.167 , pp. 120-134
    • Sampson, M.J.1    Davies, I.R.2    Braschi, S.3    Ivory, K.4    Hughes, D.A.5
  • 47
    • 0031978723 scopus 로고    scopus 로고
    • Role of macrophage glycosaminoglycans in the cellular catabolism of oxidized LDL by macrophages
    • Kaplan M., Williams K.J., Mandel H., and Aviram M. Role of macrophage glycosaminoglycans in the cellular catabolism of oxidized LDL by macrophages. Arterioscler Thromb Vasc Biol 4 (1998) 542-553
    • (1998) Arterioscler Thromb Vasc Biol , vol.4 , pp. 542-553
    • Kaplan, M.1    Williams, K.J.2    Mandel, H.3    Aviram, M.4
  • 48
    • 1842424851 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits epidermal grpwth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases
    • Sah J.F., Balasubramaniam S., Ecker R.L., and Rorke E.A. Epigallocatechin-3-gallate inhibits epidermal grpwth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. J Biol Chem 279 (2004) 12755-12762
    • (2004) J Biol Chem , vol.279 , pp. 12755-12762
    • Sah, J.F.1    Balasubramaniam, S.2    Ecker, R.L.3    Rorke, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.