메뉴 건너뛰기




Volumn 8, Issue 7, 2010, Pages 1015-1029

Atherosclerosis, diabetes and lipoproteins

Author keywords

ApoB48; atherosclerosis; diabetes; intestinal lipoproteins; lipoproteins; postprandial; triglycerides

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER G5; ABC TRANSPORTER G8; CHYLOMICRON; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ABCG5 PROTEIN, HUMAN; ABCG8 PROTEIN, HUMAN; CARRIER PROTEIN; CHOLESTEROL; MEMBRANE PROTEIN; NPC1L1 PROTEIN, HUMAN;

EID: 77954509575     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/erc.10.45     Document Type: Review
Times cited : (33)

References (154)
  • 1
    • 68349152460 scopus 로고    scopus 로고
    • No authors listed Heart disease: Breaking down barriers
    • No authors listed. Heart disease: breaking down barriers. Lancet 374, 501 (2009).
    • (2009) Lancet , vol.374 , pp. 501
  • 3
    • 70449356801 scopus 로고    scopus 로고
    • Type 2 diabetes epidemic: A global education
    • No authors listed
    • No authors listed. Type 2 diabetes epidemic: a global education. Lancet 374, 1654 (2009).
    • (2009) Lancet , vol.374 , pp. 1654
  • 5
    • 0029558769 scopus 로고
    • Dr Black's favourite disease
    • Evans A. Dr Black's favourite disease. Br. Heart J. 74, 696-697 (1995).
    • (1995) Br. Heart J. , vol.74 , pp. 696-697
    • Evans, A.1
  • 6
    • 0032693599 scopus 로고    scopus 로고
    • Atherosclerosis is an inflammatory disease
    • Ross R. Atherosclerosis is an inflammatory disease. Am. Heart J. 138, S419-S420 (1999).
    • (1999) Am. Heart J. , vol.138
    • Ross, R.1
  • 7
    • 0042665536 scopus 로고    scopus 로고
    • Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study
    • Sattar N, Gaw A, Scherbakova O et al. Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation 108, 414-419 (2003).
    • (2003) Circulation , vol.108 , pp. 414-419
    • Sattar, N.1    Gaw, A.2    Scherbakova, O.3
  • 8
    • 70349742564 scopus 로고    scopus 로고
    • C-reactive protein as a risk factor for coronary heart disease: A systematic review and meta-analyses for the U.S. Preventive Services Task Force
    • Buckley DI, Fu R, Freeman M, Rogers K, Helfand M. C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force. Ann. Intern. Med. 151, 483-495 (2009).
    • (2009) Ann. Intern. Med. , vol.151 , pp. 483-495
    • Buckley, D.I.1    Fu, R.2    Freeman, M.3    Rogers, K.4    Helfand, M.5
  • 9
    • 73449130797 scopus 로고    scopus 로고
    • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis
    • Kaptoge S, Di Angelantonio E, Lowe G et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 375, 132-140 (2010).
    • (2010) Lancet , vol.375 , pp. 132-140
    • Kaptoge, S.1    Di Angelantonio, E.2    Lowe, G.3
  • 10
    • 65949111518 scopus 로고    scopus 로고
    • Relation of abdominal fat depots to systemic markers of inflammation in Type 2 diabetes
    • Sam S, Haffner S, Davidson MH et al. Relation of abdominal fat depots to systemic markers of inflammation in Type 2 diabetes. Diabetes Care 32, 932-937 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 932-937
    • Sam, S.1    Haffner, S.2    Davidson, M.H.3
  • 11
    • 0142087611 scopus 로고    scopus 로고
    • Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells
    • Calabró P, Willerson JT, Yeh ET. Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Circulation 108, 1930-1932 (2003).
    • (2003) Circulation , vol.108 , pp. 1930-1932
    • Calabró, P.1    Willerson, J.T.2    Yeh, E.T.3
  • 12
    • 0035099170 scopus 로고    scopus 로고
    • Generation of C-reactive protein and complement components in atherosclerotic plaques
    • Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am. J. Pathol. 158, 1039-1051 (2001).
    • (2001) Am. J. Pathol. , vol.158 , pp. 1039-1051
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 13
    • 0029949314 scopus 로고    scopus 로고
    • Expression of C-reactive protein by alveolar macrophages
    • Dong Q, Wright JR. Expression of C-reactive protein by alveolar macrophages. J. Immunol. 156, 4815-4820 (1996).
    • (1996) J. Immunol. , vol.156 , pp. 4815-4820
    • Dong, Q.1    Wright, J.R.2
  • 14
    • 10744224994 scopus 로고    scopus 로고
    • Interaction of oxidative stress and inflammatory response in coronary plaque instability: Important role of C-reactive protein
    • Kobayashi S, Inoue N, Ohashi Y et al. Interaction of oxidative stress and inflammatory response in coronary plaque instability: important role of C-reactive protein. Arterioscler. Thromb. Vasc. Biol. 23, 1398-1404 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1398-1404
    • Kobayashi, S.1    Inoue, N.2    Ohashi, Y.3
  • 15
    • 17144369225 scopus 로고    scopus 로고
    • Macrophage conditioned medium induces the expression of C-reactive protein in human aortic endothelial cells: Potential for paracrine/autocrine effects
    • Venugopal SK, Devaraj S, Jialal I. Macrophage conditioned medium induces the expression of C-reactive protein in human aortic endothelial cells: potential for paracrine/autocrine effects. Am. J. Pathol. 166, 1265-1271 (2005).
    • (2005) Am. J. Pathol. , vol.166 , pp. 1265-1271
    • Venugopal, S.K.1    Devaraj, S.2    Jialal, I.3
  • 16
    • 0037126012 scopus 로고    scopus 로고
    • Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
    • Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 106, 1439-1441 (2002).
    • (2002) Circulation , vol.106 , pp. 1439-1441
    • Venugopal, S.K.1    Devaraj, S.2    Yuhanna, I.3    Shaul, P.4    Jialal, I.5
  • 17
    • 36448943247 scopus 로고    scopus 로고
    • C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling
    • Singh U, Devaraj S, Vasquez-Vivar J, Jialal I. C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling. J. Mol. Cell Cardiol. 43, 780-791 (2007).
    • (2007) J. Mol. Cell Cardiol. , vol.43 , pp. 780-791
    • Singh, U.1    Devaraj, S.2    Vasquez-Vivar, J.3    Jialal, I.4
  • 18
    • 44649103514 scopus 로고    scopus 로고
    • C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production
    • Nagaoka T, Kuo L, Ren Y, Yoshida A, Hein TW. C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production. Invest. Ophthalmol. Vis. Sci. 49, 2053-2060 (2008).
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 2053-2060
    • Nagaoka, T.1    Kuo, L.2    Ren, Y.3    Yoshida, A.4    Hein, T.W.5
  • 19
    • 18244409093 scopus 로고    scopus 로고
    • C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase
    • Qamirani E, Ren Y, Kuo L, Hein TW. C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase. Arterioscler. Thromb. Vasc. Biol. 25, 995-1001 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 995-1001
    • Qamirani, E.1    Ren, Y.2    Kuo, L.3    Hein, T.W.4
  • 20
    • 33645834145 scopus 로고    scopus 로고
    • Calcium [corrected] channel blockers reduce angiotensin II-induced superoxide generation and inhibit lectin-like oxidized low-density lipoprotein receptor-1 expression in endothelial cells
    • Toba H, Shimizu T, Miki S et al. Calcium [corrected] channel blockers reduce angiotensin II-induced superoxide generation and inhibit lectin-like oxidized low-density lipoprotein receptor-1 expression in endothelial cells. Hypertens. Res. 2, 105-116 (2006).
    • (2006) Hypertens. Res. , vol.2 , pp. 105-116
    • Toba, H.1    Shimizu, T.2    Miki, S.3
  • 21
    • 7244226296 scopus 로고    scopus 로고
    • C-reactive protein enhances LOX-1 expression in human aortic endothelial cells: Relevance of LOX-1 to C-reactive protein-induced endothelial dysfunction
    • Li L, Roumeliotis N, Sawamura T, Renier G. C-reactive protein enhances LOX-1 expression in human aortic endothelial cells: relevance of LOX-1 to C-reactive protein-induced endothelial dysfunction. Circ. Res. 95, 877-883 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 877-883
    • Li, L.1    Roumeliotis, N.2    Sawamura, T.3    Renier, G.4
  • 22
    • 46949086807 scopus 로고    scopus 로고
    • Human C-reactive protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats
    • Singh U, Dasu MR, Yancey PG, Afify A, Devaraj S, Jialal I. Human C-reactive protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats. J. Lipid Res. 49, 1015-1023 (2008).
    • (2008) J. Lipid Res. , vol.49 , pp. 1015-1023
    • Singh, U.1    Dasu, M.R.2    Yancey, P.G.3    Afify, A.4    Devaraj, S.5    Jialal, I.6
  • 24
    • 13444249472 scopus 로고    scopus 로고
    • Modification of PI3K- and MAPK-dependent chemotaxis in aortic vascular smooth muscle cells by protein kinase CbII
    • Campbell M, Trimble ER. Modification of PI3K- and MAPK-dependent chemotaxis in aortic vascular smooth muscle cells by protein kinase CbII. Circ. Res. 96, 197-206 (2005).
    • (2005) Circ. Res. , vol.96 , pp. 197-206
    • Campbell, M.1    Trimble, E.R.2
  • 25
    • 4143101425 scopus 로고    scopus 로고
    • Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways
    • Campbell M, Allen WE, Sawyer C, Vanhaesebroeck B, Trimble ER. Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. Circ. Res. 95, 380-388 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 380-388
    • Campbell, M.1    Allen, W.E.2    Sawyer, C.3    Vanhaesebroeck, B.4    Trimble, E.R.5
  • 26
    • 71649114494 scopus 로고    scopus 로고
    • Clinical implications of JUPITER (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study
    • Yang EY, Nambi V, Tang Z et al. Clinical implications of JUPITER (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study. J. Am. Coll. Cardiol. 54, 2388-2395 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , pp. 2388-2395
    • Yang, E.Y.1    Nambi, V.2    Tang, Z.3
  • 27
    • 3543146709 scopus 로고    scopus 로고
    • C-reactive protein induces apoptosis in human coronary vascular smooth muscle cells
    • Blaschke F, Bruemmer D, Yin F et al. C-reactive protein induces apoptosis in human coronary vascular smooth muscle cells. Circulation 110, 579-587 (2004).
    • (2004) Circulation , vol.110 , pp. 579-587
    • Blaschke, F.1    Bruemmer, D.2    Yin, F.3
  • 28
    • 69349104588 scopus 로고    scopus 로고
    • Lipids, atherosclerosis and CVD risk: Is CRP an innocent bystander?
    • Nordestgaard BG, Zacho J. Lipids, atherosclerosis and CVD risk: is CRP an innocent bystander? Nutr. Metab. Cardiovasc. Dis. 19, 521-524 (2009).
    • (2009) Nutr. Metab. Cardiovasc. Dis. , vol.19 , pp. 521-524
    • Nordestgaard, B.G.1    Zacho, J.2
  • 29
    • 73349104939 scopus 로고    scopus 로고
    • Does elevated C-reactive protein cause human atherothrombosis? Novel insights from genetics, intervention trials, and elsewhere
    • Nordestgaard BG. Does elevated C-reactive protein cause human atherothrombosis? Novel insights from genetics, intervention trials, and elsewhere. Curr. Opin. Lipidol. 20, 393-401 (2009).
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 393-401
    • Nordestgaard, B.G.1
  • 30
    • 59649104145 scopus 로고    scopus 로고
    • The evolving role of C-reactive protein in atherothrombosis
    • Devaraj S, Singh U, Jialal I. The evolving role of C-reactive protein in atherothrombosis. Clin. Chem. 55, 229-238 (2009).
    • (2009) Clin. Chem. , vol.55 , pp. 229-238
    • Devaraj, S.1    Singh, U.2    Jialal, I.3
  • 31
    • 62649083251 scopus 로고    scopus 로고
    • Chlamydia pneumoniae and atherosclerosis: Current state and future prospectives
    • Sessa R, Nicoletti M, Di Pietro M et al. Chlamydia pneumoniae and atherosclerosis: current state and future prospectives. Int. J. Immunopathol. Pharmacol. 22, 9-14 (2009).
    • (2009) Int. J. Immunopathol. Pharmacol. , vol.22 , pp. 9-14
    • Sessa, R.1    Nicoletti, M.2    Di Pietro, M.3
  • 32
    • 0031456505 scopus 로고    scopus 로고
    • Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions
    • Napoli C, D'Armiento FP, Mancini FP et al. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J. Clin. Invest. 100, 2680-2690 (1997).
    • (1997) J. Clin. Invest. , vol.100 , pp. 2680-2690
    • Napoli, C.1    D'Armiento, F.P.2    Mancini, F.P.3
  • 33
    • 57749092004 scopus 로고    scopus 로고
    • The pathology of atherosclerosis: Plaque development and plaque responses to medical treatment
    • Insull W Jr. The pathology of atherosclerosis: plaque development and plaque responses to medical treatment. Am. J. Med. 122(Suppl. 1), S3-S14 (2009).
    • (2009) Am. J. Med. , vol.122 , Issue.SUPPL. 1
    • Insull Jr., W.1
  • 34
    • 0026469336 scopus 로고
    • The process of atherogenesis - Cellular and molecular interaction: From experimental animals to humans
    • Ross R, Agius L. The process of atherogenesis - cellular and molecular interaction: from experimental animals to humans. Diabetologia 35(Suppl. 2), S34-S40 (1992).
    • (1992) Diabetologia , vol.35 , Issue.SUPPL. 2
    • Ross, R.1    Agius, L.2
  • 35
    • 42549152982 scopus 로고    scopus 로고
    • Stents versus coronary-artery bypass grafting for left main coronary artery disease
    • Seung KB, Park DW, Kim YH et al. Stents versus coronary-artery bypass grafting for left main coronary artery disease. N. Engl. J. Med. 358, 1781-1792 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1781-1792
    • Seung, K.B.1    Park, D.W.2    Kim, Y.H.3
  • 36
    • 67149136723 scopus 로고    scopus 로고
    • Diabetes with coronary disease - A moving target amid evolving therapies?
    • Boden WE, Taggart DP. Diabetes with coronary disease - a moving target amid evolving therapies? N. Engl. J. Med. 360, 2570-2572 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2570-2572
    • Boden, W.E.1    Taggart, D.P.2
  • 37
    • 24944538001 scopus 로고    scopus 로고
    • Acute coronary syndromes without ST-segment elevation - What is the role of early intervention?
    • Boden WE. Acute coronary syndromes without ST-segment elevation - what is the role of early intervention? N. Engl. J. Med. 353, 1159-1161 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1159-1161
    • Boden, W.E.1
  • 38
    • 0032789444 scopus 로고    scopus 로고
    • Nitric oxide: A unique endogenous signaling molecule in vascular biology
    • Ignarro LJ. Nitric oxide: a unique endogenous signaling molecule in vascular biology. Biosci. Rep. 19, 51-71 (1999).
    • (1999) Biosci. Rep. , vol.19 , pp. 51-71
    • Ignarro, L.J.1
  • 39
    • 69949111623 scopus 로고    scopus 로고
    • Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases
    • Napoli C, Ignarro LJ. Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases. Arch. Pharm. Res. 32, 1103-1108 (2009).
    • (2009) Arch. Pharm. Res. , vol.32 , pp. 1103-1108
    • Napoli, C.1    Ignarro, L.J.2
  • 40
    • 37349128539 scopus 로고    scopus 로고
    • The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans
    • Lavi S, Yang EH, Prasad A et al. The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans. Hypertension 51, 127-133 (2008).
    • (2008) Hypertension , vol.51 , pp. 127-133
    • Lavi, S.1    Yang, E.H.2    Prasad, A.3
  • 41
    • 49849088365 scopus 로고    scopus 로고
    • The flame that lights the fire: Oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension
    • Schiffrin EL. The flame that lights the fire: oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension. Hypertension 52, 205-206 (2008).
    • (2008) Hypertension , vol.52 , pp. 205-206
    • Schiffrin, E.L.1
  • 42
    • 5444239280 scopus 로고    scopus 로고
    • Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis
    • Ignarro LJ, Napoli C. Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis. Curr. Atheroscler. Rep. 6(4), 281-287 (2004).
    • (2004) Curr. Atheroscler. Rep. , vol.6 , Issue.4 , pp. 281-287
    • Ignarro, L.J.1    Napoli, C.2
  • 43
    • 0033973485 scopus 로고    scopus 로고
    • High density lipoprotein oxidation: In vitro susceptibility and potential in vivo consequences
    • Francis GA. High density lipoprotein oxidation: in vitro susceptibility and potential in vivo consequences. Biochim. Biophys. Acta 1483, 217-235 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1483 , pp. 217-235
    • Francis, G.A.1
  • 44
    • 74049093243 scopus 로고    scopus 로고
    • The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression
    • Tabas I, Tall A, Accili D. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circ. Res. 106, 58-67 (2010).
    • (2010) Circ. Res. , vol.106 , pp. 58-67
    • Tabas, I.1    Tall, A.2    Accili, D.3
  • 45
    • 34250214950 scopus 로고    scopus 로고
    • The macrophage at the crossroads of insulin resistance and atherosclerosis
    • Liang CP, Han S, Senokuchi T, Tall AR. The macrophage at the crossroads of insulin resistance and atherosclerosis. Circ. Res. 100, 1546-1555 (2007).
    • (2007) Circ. Res. , vol.100 , pp. 1546-1555
    • Liang, C.P.1    Han, S.2    Senokuchi, T.3    Tall, A.R.4
  • 46
    • 72949116358 scopus 로고    scopus 로고
    • Macrophage death and defective inflammation resolution in atherosclerosis
    • Tabas I. Macrophage death and defective inflammation resolution in atherosclerosis. Nat. Rev. Immunol. 10, 36-46 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 36-46
    • Tabas, I.1
  • 47
    • 0036852824 scopus 로고    scopus 로고
    • Innate and acquired immunity in atherogenesis
    • Binder CJ, Cheung MK, Shaw PX et al. Innate and acquired immunity in atherogenesis. Nat. Med. 8, 1218-1226 (2002).
    • (2002) Nat. Med. , vol.8 , pp. 1218-1226
    • Binder, C.J.1    Cheung, M.K.2    Shaw, P.X.3
  • 48
    • 0033820636 scopus 로고    scopus 로고
    • Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells
    • Napoli C, Quehenberger O, De Nigris F, Abete P, Glass CK, Palinski W. Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells. FASEB J. 14, 1996-2007 (2000).
    • (2000) FASEB J , vol.14 , pp. 1996-2007
    • Napoli, C.1    Quehenberger, O.2    De Nigris, F.3    Abete, P.4    Glass, C.K.5    Palinski, W.6
  • 49
    • 0034035885 scopus 로고    scopus 로고
    • Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis
    • Palinski W, Witztum JL. Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis. J. Intern. Med. 247, 371-380 (2000).
    • (2000) J. Intern. Med. , vol.247 , pp. 371-380
    • Palinski, W.1    Witztum, J.L.2
  • 50
    • 11144224296 scopus 로고    scopus 로고
    • Immunomodulation of atherosclerosis: Implications for vaccine development
    • Nilsson J, Hansson GK, Shah PK. Immunomodulation of atherosclerosis: implications for vaccine development. Arterioscler. Thromb. Vasc. Biol. 25, 18-28 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 18-28
    • Nilsson, J.1    Hansson, G.K.2    Shah, P.K.3
  • 52
    • 21044439562 scopus 로고    scopus 로고
    • Atheroprotective immunization with MDA-modified Apo B-100 peptide sequences is associated with activation of Th2 specific antibody expression
    • Fredrikson GN, Andersson L, Söderberg I et al. Atheroprotective immunization with MDA-modified Apo B-100 peptide sequences is associated with activation of Th2 specific antibody expression. Autoimmunity 38, 171-179 (2005).
    • (2005) Autoimmunity , vol.38 , pp. 171-179
    • Fredrikson, G.N.1    Andersson, L.2    Söderberg, I.3
  • 53
    • 0038639407 scopus 로고    scopus 로고
    • Inhibition of atherosclerosis in ApoE-null mice by immunization with ApoB-100 peptide sequences
    • Fredrikson GN, Söderberg I, Lindholm M et al. Inhibition of atherosclerosis in ApoE-null mice by immunization with ApoB-100 peptide sequences. Arterioscler. Thromb. Vasc. Biol. 23, 879-884 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 879-884
    • Fredrikson, G.N.1    Söderberg, I.2    Lindholm, M.3
  • 54
    • 67349151367 scopus 로고    scopus 로고
    • Associations between autoantibodies against apolipoprotein B-100 peptides and vascular complications in patients with Type 2 diabetes
    • Fredrikson GN, Anand DV, Hopkins D et al. Associations between autoantibodies against apolipoprotein B-100 peptides and vascular complications in patients with Type 2 diabetes. Diabetologia 52, 1426-1433 (2009).
    • (2009) Diabetologia , vol.52 , pp. 1426-1433
    • Fredrikson, G.N.1    Anand, D.V.2    Hopkins, D.3
  • 55
    • 77950020916 scopus 로고    scopus 로고
    • Toll like receptor 4 in atherosclerosis and plaque destabilization
    • den Dekker WK, Cheng C, Pasterkamp G, Duckers HJ. Toll like receptor 4 in atherosclerosis and plaque destabilization. Atherosclerosis 209(2), 314-320 (2009).
    • (2009) Atherosclerosis , vol.209 , Issue.2 , pp. 314-320
    • Den Dekker, W.K.1    Cheng, C.2    Pasterkamp, G.3    Duckers, H.J.4
  • 56
    • 0027183867 scopus 로고
    • Glycosylated low density lipoprotein is more sensitive to oxidation: Implications for the diabetic patient?
    • Bowie A, Owens D, Collins P, Johnson A, Tomkin GH. Glycosylated low density lipoprotein is more sensitive to oxidation: implications for the diabetic patient? Atherosclerosis 102, 63-67 (1993).
    • (1993) Atherosclerosis , vol.102 , pp. 63-67
    • Bowie, A.1    Owens, D.2    Collins, P.3    Johnson, A.4    Tomkin, G.H.5
  • 57
    • 0035281469 scopus 로고    scopus 로고
    • Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease
    • DOI 10.1016/S0735-1097(00)01199-2, PII S0735109700011992
    • Inoue T, Uchida T, Kamishirado H, Takayanagi K, Hayashi T, Morooka S. Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease. J. Am. Coll. Cardiol. 37, 775-779 (2001). (Pubitemid 32202444)
    • (2001) Journal of the American College of Cardiology , vol.37 , Issue.3 , pp. 775-779
    • Inoue, T.1    Uchida, T.2    Kamishirado, H.3    Takayanagi, K.4    Hayashi, T.5    Morooka, S.6
  • 58
    • 0038463522 scopus 로고    scopus 로고
    • Autoantibodies against modified low-density lipoproteins in coronary artery disease
    • Tornvall P, Waeg G, Nilsson J, Hamsten A, Regnström J. Autoantibodies against modified low-density lipoproteins in coronary artery disease. Atherosclerosis 167, 347-353 (2003).
    • (2003) Atherosclerosis , vol.167 , pp. 347-353
    • Tornvall, P.1    Waeg, G.2    Nilsson, J.3    Hamsten, A.4    Regnström, J.5
  • 59
    • 0242381313 scopus 로고    scopus 로고
    • Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis
    • Karvonen J, Päivänsalo M, Kesäniemi YA, Hörkkö S. Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis. Circulation 108, 2107-2112 (2003).
    • (2003) Circulation , vol.108 , pp. 2107-2112
    • Karvonen, J.1    Päivänsalo, M.2    Kesäniemi, Y.A.3    Hörkkö, S.4
  • 60
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes (UKPDS 33). Lancet 352, 837-853 (1998).
    • (1998) Lancet , vol.352 , pp. 837-853
  • 61
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with Type 2 diabetes
    • Patel A, MacMahon S, Chalmers J et al. Intensive blood glucose control and vascular outcomes in patients with Type 2 diabetes. N. Engl. J. Med. 358, 2560-2572 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2560-2572
    • Patel, A.1    MacMahon, S.2    Chalmers, J.3
  • 62
    • 45149131667 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in Type 2 diabetes
    • Action to Control Cardiovascular Risk in Diabetes Study Group
    • Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in Type 2 diabetes. N. Engl. J. Med. 358, 2545-2559 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2545-2559
  • 63
    • 0037965858 scopus 로고    scopus 로고
    • Diabetes: Mellitus or lipidus?
    • Shafrir E, Raz I. Diabetes: mellitus or lipidus? Diabetologia 46, 433-440 (2003).
    • (2003) Diabetologia , vol.46 , pp. 433-440
    • Shafrir, E.1    Raz, I.2
  • 64
    • 0038466496 scopus 로고
    • Patterns of decrease of free fatty acids during glucose tolerence tests
    • Shafrir E, Gutman A. Patterns of decrease of free fatty acids during glucose tolerence tests. Diabetes 14, 77-83 (1965).
    • (1965) Diabetes , vol.14 , pp. 77-83
    • Shafrir, E.1    Gutman, A.2
  • 65
    • 0035859849 scopus 로고    scopus 로고
    • Plasma nonesterified fatty acid concentration as a risk factor for sudden cardiac death: The Paris Prospective Study
    • Leaf A. Plasma nonesterified fatty acid concentration as a risk factor for sudden cardiac death: the Paris Prospective Study. Circulation 104, 744-745 (2001).
    • (2001) Circulation , vol.104 , pp. 744-745
    • Leaf, A.1
  • 66
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 298, 299-308 (2007).
    • (2007) JAMA , vol.298 , pp. 299-308
    • Nordestgaard, B.G.1    Benn, M.2    Schnohr, P.3    Tybjaerg-Hansen, A.4
  • 67
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 298, 309-316 (2007).
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6
  • 68
    • 54049094000 scopus 로고    scopus 로고
    • FOXO1 integrates insulin signaling to VLDL production
    • Kamagate A, Dong HH. FOXO1 integrates insulin signaling to VLDL production. Cell Cycle 7, 3162-3170 (2008).
    • (2008) Cell Cycle , vol.7 , pp. 3162-3170
    • Kamagate, A.1    Dong, H.H.2
  • 69
    • 45549090182 scopus 로고    scopus 로고
    • Inactivation of hepatic FOXO1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
    • Dong XC, Copps KD, Guo S et al. Inactivation of hepatic FOXO1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab. 8, 65-76 (2008).
    • (2008) Cell Metab , vol.8 , pp. 65-76
    • Dong, X.C.1    Copps, K.D.2    Guo, S.3
  • 70
    • 77955845052 scopus 로고    scopus 로고
    • Lipoprotein metabolism mediates the association of MTP polymorphism with b-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis
    • DOI: 10.1016/j. jnutbio.2009.06.007, Epub ahead of print
    • Musso G, Gambino R, Cassader M. Lipoprotein metabolism mediates the association of MTP polymorphism with b-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis. J. Nutr. Biochem. DOI: 10.1016/j. jnutbio.2009.06.007 (2009) (Epub ahead of print).
    • (2009) J. Nutr. Biochem.
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 71
    • 0034691299 scopus 로고    scopus 로고
    • Cardiovascular disease mortality in familial forms of hypertriglyceridemia: A 20-year prospective study
    • Austin MA, McKnight B, Edwards KL et al. Cardiovascular disease mortality in familial forms of hypertriglyceridemia: a 20-year prospective study. Circulation 101, 2777-2782 (2000).
    • (2000) Circulation , vol.101 , pp. 2777-2782
    • Austin, M.A.1    McKnight, B.2    Edwards, K.L.3
  • 72
    • 0001575898 scopus 로고    scopus 로고
    • Type III hyperlipoproteinemia (dysbetalipoproteinemia): The role of apolipoprotein e in normal and abnormal lipoprotein metabolism
    • (8th Edition). Scriver CR, Beaudet AL, Sly WS, Valle D (Eds). McGraw-Hill, NY, USA
    • Mahley RW, Rall SC. Type III hyperlipoproteinemia (dysbetalipoproteinemia): the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: The Metabolic & Molecular Bases of Inherited Disease (8th Edition). Scriver CR, Beaudet AL, Sly WS, Valle D (Eds). McGraw-Hill, NY, USA, 2835-2862 (2001).
    • (2001) The Metabolic & Molecular Bases of Inherited Disease , pp. 2835-2862
    • Mahley, R.W.1    Rall, S.C.2
  • 73
    • 33644502854 scopus 로고    scopus 로고
    • The metabolic syndrome: Prevalence CHD risk and treatment
    • Sarti C, Gallagher J. The metabolic syndrome: prevalence, CHD risk, and treatment. J. Diabetes Complicat. 20, 121-132 (2006).
    • (2006) J. Diabetes Complicat. , vol.20 , pp. 121-132
    • Sarti, C.1    Gallagher, J.2
  • 74
    • 0002316655 scopus 로고    scopus 로고
    • Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency
    • (8th Edition). Scriver CR, Beaudet AL, Sly WS, Valle D (Eds). McGraw-Hill, NY, USA
    • Brunzell JD, Deeb SS. Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency. In: The Metabolic & Molecular Bases of Inherited Disease (8th Edition). Scriver CR, Beaudet AL, Sly WS, Valle D (Eds). McGraw-Hill, NY, USA, 2789-2816 (2001).
    • (2001) The Metabolic & Molecular Bases of Inherited Disease , pp. 2789-2816
    • Brunzell, J.D.1    Deeb, S.S.2
  • 75
    • 0035573979 scopus 로고    scopus 로고
    • Postprandial increase of complement component 3 in normolipidemic patients with coronary artery disease: Effects of expanded-dose simvastatin
    • Halkes CJ, van Dijk H, de Jaegere PP et al. Postprandial increase of complement component 3 in normolipidemic patients with coronary artery disease: effects of expanded-dose simvastatin. Arterioscler. Thromb. Vasc. Biol. 9, 1526-1530 (2001).
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.9 , pp. 1526-1530
    • Halkes, C.J.1    Van Dijk, H.2    De Jaegere, P.P.3
  • 76
    • 0042572498 scopus 로고    scopus 로고
    • A combination of high concentrations of serum triglyceride and non-high-density-lipoprotein-cholesterol is a risk factor for cardiovascular disease in subjects with abnormal glucose metabolism - The Hoorn Study
    • Bos G, Dekker JM, Nijpels G et al. A combination of high concentrations of serum triglyceride and non-high-density-lipoprotein-cholesterol is a risk factor for cardiovascular disease in subjects with abnormal glucose metabolism - the Hoorn Study. Diabetologia 46, 910-916 (2003).
    • (2003) Diabetologia , vol.46 , pp. 910-916
    • Bos, G.1    Dekker, J.M.2    Nijpels, G.3
  • 77
    • 0036554781 scopus 로고    scopus 로고
    • Coronary heart disease risk factors ranked by importance for the individual and community: A 21-year follow-up of 12 000 men and women from the Copenhagen City Heart Study
    • Schnohr P, Jensen JS, Scharling H, Nordestgaard BG. Coronary heart disease risk factors ranked by importance for the individual and community: a 21-year follow-up of 12 000 men and women from the Copenhagen City Heart Study. Eur. Heart J. 23, 620-626 (2002).
    • (2002) Eur. Heart J. , vol.23 , pp. 620-626
    • Schnohr, P.1    Jensen, J.S.2    Scharling, H.3    Nordestgaard, B.G.4
  • 78
    • 33846637379 scopus 로고    scopus 로고
    • Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies
    • Sarwar N, Danesh J, Eiriksdottir G et al. Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation 115, 450-458 (2007).
    • (2007) Circulation , vol.115 , pp. 450-458
    • Sarwar, N.1    Danesh, J.2    Eiriksdottir, G.3
  • 79
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary-artery disease in Type 2 diabetes: The Diabetes Atherosclerosis Intervention Study (DAIS), a randomised study
    • No authors listed
    • No authors listed. Effect of fenofibrate on progression of coronary-artery disease in Type 2 diabetes: the Diabetes Atherosclerosis Intervention Study (DAIS), a randomised study. Lancet 357, 905-910 (2001).
    • (2001) Lancet , vol.357 , pp. 905-910
  • 80
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with Type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • Keech A, Simes RJ, Barter P et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with Type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 366, 1849-1861 (2005).
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3
  • 81
    • 73849086222 scopus 로고    scopus 로고
    • Combination therapy of statins and fibrates in the management of cardiovascular risk
    • Fiévet C, Staels B. Combination therapy of statins and fibrates in the management of cardiovascular risk. Curr. Opin. Lipidol. 20, 505-511 (2009).
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 505-511
    • Fiévet, C.1    Staels, B.2
  • 82
    • 0037121346 scopus 로고    scopus 로고
    • Bezafibrate in men with lower extremity arterial disease: Randomised controlled trial
    • Meade T, Zuhrie R, Cook C, Cooper J. Bezafibrate in men with lower extremity arterial disease: randomised controlled trial. Br. Med. J. 325, 1139 (2002).
    • (2002) Br. Med. J. , vol.325 , pp. 1139
    • Meade, T.1    Zuhrie, R.2    Cook, C.3    Cooper, J.4
  • 83
    • 9444293381 scopus 로고    scopus 로고
    • Determination of apolipoprotein B-48 in serum by a sandwich ELISA
    • Kinoshita M, Kojima M, Matsushima T, Teramoto T. Determination of apolipoprotein B-48 in serum by a sandwich ELISA. Clin. Chim. Acta 351, 115-120 (2005).
    • (2005) Clin. Chim. Acta , vol.351 , pp. 115-120
    • Kinoshita, M.1    Kojima, M.2    Matsushima, T.3    Teramoto, T.4
  • 84
    • 0018649439 scopus 로고
    • Atherogenesis: A postprandial phenomenon
    • Zilversmit DB. Atherogenesis: a postprandial phenomenon. Circulation 60, 473-485 (1979).
    • (1979) Circulation , vol.60 , pp. 473-485
    • Zilversmit, D.B.1
  • 86
    • 0042074140 scopus 로고    scopus 로고
    • Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: A case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study
    • Hopkins PN, Heiss G, Ellison RC et al. Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study. Circulation 108, 519-523 (2003).
    • (2003) Circulation , vol.108 , pp. 519-523
    • Hopkins, P.N.1    Heiss, G.2    Ellison, R.C.3
  • 87
    • 0042691798 scopus 로고    scopus 로고
    • Intimal retention of cholesterol derived from apolipoprotein B100- and apolipoprotein B48-containing lipoproteins in carotid arteries of Watanabe heritable hyperlipidemic rabbits
    • Proctor SD, Mamo JC. Intimal retention of cholesterol derived from apolipoprotein B100- and apolipoprotein B48-containing lipoproteins in carotid arteries of Watanabe heritable hyperlipidemic rabbits. Arterioscler. Thromb. Vasc. Biol. 23, 1595-1600 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1595-1600
    • Proctor, S.D.1    Mamo, J.C.2
  • 88
    • 0038573898 scopus 로고    scopus 로고
    • Identification of lipoproteins of intestinal origin in human atherosclerotic plaque
    • Pal S, Semorine K, Watts GF, Mamo J. Identification of lipoproteins of intestinal origin in human atherosclerotic plaque. Clin. Chem. Lab. Med. 41, 792-795 (2003).
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 792-795
    • Pal, S.1    Semorine, K.2    Watts, G.F.3    Mamo, J.4
  • 89
    • 39649120533 scopus 로고    scopus 로고
    • Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases
    • Nakano T, Nakajima K, Niimi M et al. Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases. Clin. Chim. Acta 390, 38-43 (2008).
    • (2008) Clin. Chim. Acta , vol.390 , pp. 38-43
    • Nakano, T.1    Nakajima, K.2    Niimi, M.3
  • 90
    • 0019828002 scopus 로고
    • Uptake of chylomicron remnants by the native LDL receptor in human monocyte-derived macrophages
    • Floren CH, Chait A. Uptake of chylomicron remnants by the native LDL receptor in human monocyte-derived macrophages. Biochim. Biophys. Acta 665, 608-611 (1981).
    • (1981) Biochim. Biophys. Acta , vol.665 , pp. 608-611
    • Floren, C.H.1    Chait, A.2
  • 91
    • 0027989299 scopus 로고
    • Cellular binding site and membrane binding proteins for triglyceride-rich lipoproteins in human monocyte-macrophages and THP-1 monocytic cells
    • Gianturco SH, Ramprasad MP, Lin AH, Song R, Bradley WA. Cellular binding site and membrane binding proteins for triglyceride-rich lipoproteins in human monocyte-macrophages and THP-1 monocytic cells. J. Lipid Res. 35, 1674-1687 (1994).
    • (1994) J. Lipid Res. , vol.35 , pp. 1674-1687
    • Gianturco, S.H.1    Ramprasad, M.P.2    Lin, A.H.3    Song, R.4    Bradley, W.A.5
  • 93
    • 0034878974 scopus 로고    scopus 로고
    • Binding and uptake of chylomicron remnants by primary and THP-1 human monocyte-derived macrophages: Determination of binding proteins
    • Elsegood CL, Pal S, Roach PD, Mamo JC. Binding and uptake of chylomicron remnants by primary and THP-1 human monocyte-derived macrophages: determination of binding proteins. Clin. Sci. (Lond.) 101, 111-119 (2001).
    • (2001) Clin. Sci. (Lond.) , vol.101 , pp. 111-119
    • Elsegood, C.L.1    Pal, S.2    Roach, P.D.3    Mamo, J.C.4
  • 94
    • 33748045788 scopus 로고    scopus 로고
    • An investigation by electron microscopy of chylomicron remnant uptake by human monocyte-derived macrophages
    • Elsegood CL, Mamo JC. An investigation by electron microscopy of chylomicron remnant uptake by human monocyte-derived macrophages. Atherosclerosis 188, 251-259 (2006).
    • (2006) Atherosclerosis , vol.188 , pp. 251-259
    • Elsegood, C.L.1    Mamo, J.C.2
  • 95
    • 50449099694 scopus 로고    scopus 로고
    • Are we ready for a prospective study to investigate the role of chylomicrons in cardiovascular disease?
    • Cohn JS. Are we ready for a prospective study to investigate the role of chylomicrons in cardiovascular disease? Atherosclerosis Suppl. 9, 15-18 (2008).
    • (2008) Atherosclerosis , vol.9 , Issue.SUPPL. , pp. 15-18
    • Cohn, J.S.1
  • 96
    • 0033959286 scopus 로고    scopus 로고
    • Improved metabolic control reduces the number of postprandial apolipoprotein B-48- containing particles in Type 2 diabetes
    • Phillips C, Murugasu G, Owens D, Collins P, Johnson A, Tomkin GH. Improved metabolic control reduces the number of postprandial apolipoprotein B-48- containing particles in Type 2 diabetes. Atherosclerosis 148, 283-291 (2000).
    • (2000) Atherosclerosis , vol.148 , pp. 283-291
    • Phillips, C.1    Murugasu, G.2    Owens, D.3    Collins, P.4    Johnson, A.5    Tomkin, G.H.6
  • 98
    • 0025845115 scopus 로고
    • Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptation
    • Kern F Jr. Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptation. N. Engl. J. Med. 324, 896-899 (1991).
    • (1991) N. Engl. J. Med. , vol.324 , pp. 896-899
    • Kern Jr., F.1
  • 99
    • 10744221008 scopus 로고    scopus 로고
    • Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption
    • Altmann SW, Davis HR Jr, Zhu IJ et al. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 303, 1201-1204 (2004).
    • (2004) Science , vol.303 , pp. 1201-1204
    • Altmann, S.W.1    Davis Jr., H.R.2    Zhu, I.J.3
  • 100
    • 37249042184 scopus 로고    scopus 로고
    • Fenofibrate reduces intestinal cholesterol absorption via PPAR{a}-dependent modulation of NPC1L1 expression in mouse
    • Valasek MA, Clarke SL, Repa JJ. Fenofibrate reduces intestinal cholesterol absorption via PPAR{a}-dependent modulation of NPC1L1 expression in mouse. J. Lipid Res. 48, 2725-2735 (2007).
    • (2007) J. Lipid Res. , vol.48 , pp. 2725-2735
    • Valasek, M.A.1    Clarke, S.L.2    Repa, J.J.3
  • 101
    • 0035942162 scopus 로고    scopus 로고
    • A selective peroxisome proliferator-activated receptor d agonist promotes reverse cholesterol transport
    • Oliver WR Jr, Shenk JL, Snaith MR et al. A selective peroxisome proliferator-activated receptor d agonist promotes reverse cholesterol transport Proc. Natl Acad. Sci. USA 98, 5306-5311 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5306-5311
    • Oliver Jr., W.R.1    Shenk, J.L.2    Snaith, M.R.3
  • 102
    • 70350370460 scopus 로고    scopus 로고
    • PPARd activation leads to increased trans intestinal cholesterol efflux
    • Vrins CL, Van der Velde AE, Van den Oever K et al. PPARd activation leads to increased trans intestinal cholesterol efflux. J. Lipid Res. 50, 2046-2054 (2009).
    • (2009) J. Lipid Res. , vol.50 , pp. 2046-2054
    • Vrins, C.L.1    Van Der Velde, A.E.2    Van Den Oever, K.3
  • 103
    • 70350371463 scopus 로고    scopus 로고
    • Alterations in cholesterol absorption/ synthesis markers characterize Framingham offspring study participants with CHD
    • Matthan NR, Pencina M, LaRocque JM et al. Alterations in cholesterol absorption/ synthesis markers characterize Framingham offspring study participants with CHD. J. Lipid Res. 50, 1927-1935 (2009).
    • (2009) J. Lipid Res. , vol.50 , pp. 1927-1935
    • Matthan, N.R.1    Pencina, M.2    Larocque, J.M.3
  • 104
    • 64749098665 scopus 로고    scopus 로고
    • The relationships of cholesterol metabolism and plasma plant sterols with the severity of coronary artery disease
    • Silbernagel G, Fauler G, Renner W et al. The relationships of cholesterol metabolism and plasma plant sterols with the severity of coronary artery disease. J. Lipid Res. 50, 334-341 (2009).
    • (2009) J. Lipid Res. , vol.50 , pp. 334-341
    • Silbernagel, G.1    Fauler, G.2    Renner, W.3
  • 105
    • 74049133921 scopus 로고    scopus 로고
    • In vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers
    • Yamanashi Y, Takada T, Suzuki H. In vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers. Pharmacogenet. Genomics 19(11), 884-892 (2009).
    • (2009) Pharmacogenet. Genomics , vol.19 , Issue.11 , pp. 884-892
    • Yamanashi, Y.1    Takada, T.2    Suzuki, H.3
  • 106
    • 28644452453 scopus 로고    scopus 로고
    • Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment
    • Simon JS, Karnoub MC, Devlin DJ et al. Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment. Genomics 86, 648-656 (2005).
    • (2005) Genomics , vol.86 , pp. 648-656
    • Simon, J.S.1    Karnoub, M.C.2    Devlin, D.J.3
  • 107
    • 77951069483 scopus 로고    scopus 로고
    • Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly
    • Polisecki E, Peter I, Simon JS et al. Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. J. Lipid Res. 51(5), 1201-1207 (2009).
    • (2009) J. Lipid Res. , vol.51 , Issue.5 , pp. 1201-1207
    • Polisecki, E.1    Peter, I.2    Simon, J.S.3
  • 108
    • 34447320754 scopus 로고    scopus 로고
    • The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes
    • Lally S, Owens D, Tomkin GH. The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes. Atherosclerosis 193, 343-351 (2007).
    • (2007) Atherosclerosis , vol.193 , pp. 343-351
    • Lally, S.1    Owens, D.2    Tomkin, G.H.3
  • 109
    • 33646412333 scopus 로고    scopus 로고
    • Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in Type 2 diabetes: The role of Niemann- Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein
    • Lally S, Tan CY, Owens D, Tomkin GH. Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in Type 2 diabetes: the role of Niemann- Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein. Diabetologia 49, 1008-1016 (2006).
    • (2006) Diabetologia , vol.49 , pp. 1008-1016
    • Lally, S.1    Tan, C.Y.2    Owens, D.3    Tomkin, G.H.4
  • 110
    • 33751439597 scopus 로고    scopus 로고
    • Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins
    • Staprans I, Pan XM, Rapp JH, Moser AH, Feingold KR. Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins. J. Lipid Res. 47, 2575-2580 (2006).
    • (2006) J. Lipid Res. , vol.47 , pp. 2575-2580
    • Staprans, I.1    Pan, X.M.2    Rapp, J.H.3    Moser, A.H.4    Feingold, K.R.5
  • 111
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
    • Berge KE, Tian H, Graf GA et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290, 1771-1775 (2000).
    • (2000) Science , vol.290 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3
  • 113
    • 0348111456 scopus 로고    scopus 로고
    • ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary excretion
    • Graf GA, Yu L, Li WP et al. ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary excretion. J. Biol. Chem. 278, 48275-48282 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 48275-48282
    • Graf, G.A.1    Yu, L.2    Li, W.P.3
  • 114
    • 34247399882 scopus 로고    scopus 로고
    • Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in ABCG8(-/-) mice
    • Wang HH, Patel SB, Carey MC, Wang DQ. Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in ABCG8(-/-) mice. Hepatology 45, 998-1006 (2007).
    • (2007) Hepatology , vol.45 , pp. 998-1006
    • Wang, H.H.1    Patel, S.B.2    Carey, M.C.3    Wang, D.Q.4
  • 115
    • 37249034137 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in ABCG5 and ABCG8 are associated with changes in cholesterol metabolism during weight loss
    • Santosa S, Demonty I, Lichtenstein AH, Ordovas JM, Jones PJ. Single nucleotide polymorphisms in ABCG5 and ABCG8 are associated with changes in cholesterol metabolism during weight loss. J. Lipid Res. 48, 2607-2613 (2007).
    • (2007) J. Lipid Res. , vol.48 , pp. 2607-2613
    • Santosa, S.1    Demonty, I.2    Lichtenstein, A.H.3    Ordovas, J.M.4    Jones, P.J.5
  • 116
    • 4644279032 scopus 로고    scopus 로고
    • Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity
    • Gylling H, Hallikainen M, Pihlajamäki J et al. Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity. J. Lipid Res. 45, 1660-1665 (2004).
    • (2004) J. Lipid Res. , vol.45 , pp. 1660-1665
    • Gylling, H.1    Hallikainen, M.2    Pihlajamäki, J.3
  • 117
    • 0942279560 scopus 로고    scopus 로고
    • Down-regulation of hepatic and intestinal ABCG5 and ABCG8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes
    • Bloks VW, Bakker-Van Waarde WM, Verkade HJ et al. Down-regulation of hepatic and intestinal ABCG5 and ABCG8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes. Diabetologia 47, 104-112 (2004).
    • (2004) Diabetologia , vol.47 , pp. 104-112
    • Bloks, V.W.1    Bakker-Van Waarde, W.M.2    Verkade, H.J.3
  • 118
    • 33846829068 scopus 로고    scopus 로고
    • Genes that affect cholesterol synthesis, cholesterol absorption and chylomicron assembly. The relationship between the liver and intestine in control and streptozotosin diabetic rats
    • Lally S, Owens D, Tomkin GH. Genes that affect cholesterol synthesis, cholesterol absorption and chylomicron assembly. The relationship between the liver and intestine in control and streptozotosin diabetic rats. Metabolism 56, 430-438 (2007).
    • (2007) Metabolism , vol.56 , pp. 430-438
    • Lally, S.1    Owens, D.2    Tomkin, G.H.3
  • 119
    • 1842834052 scopus 로고    scopus 로고
    • A common microsomal triglyceride transfer protein polymorphism significantly reduces low density lipoprotein cholesterol in Type 2 diabetic patients through its effect on the triglyceride-rich lipoproteins
    • Phillips C, Mullan K, Owens D, Tomkin GH. A common microsomal triglyceride transfer protein polymorphism significantly reduces low density lipoprotein cholesterol in Type 2 diabetic patients through its effect on the triglyceride-rich lipoproteins. QJM 97, 211-218 (2004).
    • (2004) QJM , vol.97 , pp. 211-218
    • Phillips, C.1    Mullan, K.2    Owens, D.3    Tomkin, G.H.4
  • 120
    • 0031807231 scopus 로고    scopus 로고
    • A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels
    • Karpe F, Lundahl B, Ehrenborg E, Eriksson P, Hamsten A. A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels. Atheroscler. Thromb. Vasc. Biol. 18(5), 756-761 (1998).
    • (1998) Atheroscler. Thromb. Vasc. Biol. , vol.18 , Issue.5 , pp. 756-761
    • Karpe, F.1    Lundahl, B.2    Ehrenborg, E.3    Eriksson, P.4    Hamsten, A.5
  • 121
    • 2442675345 scopus 로고    scopus 로고
    • The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease
    • Ledmyr H, McMahon AD, Ehrenborg E et al. The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. Circulation 109, 2279-2284 (2004).
    • (2004) Circulation , vol.109 , pp. 2279-2284
    • Ledmyr, H.1    McMahon, A.D.2    Ehrenborg, E.3
  • 122
    • 26844580001 scopus 로고    scopus 로고
    • JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
    • Aggarwal D, West KL, Zern TL, Shrestha S, Vergara-Jimenez M, Fernandez ML. JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs. BMC Cardiovasc. Disord. 5, 30 (2005).
    • (2005) BMC Cardiovasc. Disord. , vol.5 , pp. 30
    • Aggarwal, D.1    West, K.L.2    Zern, T.L.3    Shrestha, S.4    Vergara-Jimenez, M.5    Fernandez, M.L.6
  • 123
    • 0033846558 scopus 로고    scopus 로고
    • Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with Type II diabetes
    • Bernard S, Touzet S, Personne I et al. Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with Type II diabetes. Diabetologia 43, 995-999 (2000).
    • (2000) Diabetologia , vol.43 , pp. 995-999
    • Bernard, S.1    Touzet, S.2    Personne, I.3
  • 124
    • 68549104176 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein gene polymorphism strongly influences circulating malondialdehyde-modified low-density lipoprotein
    • Okumura K, Imamura A, Murakami R et al. Microsomal triglyceride transfer protein gene polymorphism strongly influences circulating malondialdehyde- modified low-density lipoprotein. Metabolism 58, 1306-1311 (2009).
    • (2009) Metabolism , vol.58 , pp. 1306-1311
    • Okumura, K.1    Imamura, A.2    Murakami, R.3
  • 125
    • 0032813673 scopus 로고    scopus 로고
    • The role of microsomal triglyceride transfer protein and dietary cholesterol in chylomicron production in diabetes
    • Gleeson A, Anderton K, Owens D et al. The role of microsomal triglyceride transfer protein and dietary cholesterol in chylomicron production in diabetes. Diabetologia 42, 944-949 (1999).
    • (1999) Diabetologia , vol.42 , pp. 944-949
    • Gleeson, A.1    Anderton, K.2    Owens, D.3
  • 126
    • 0036064687 scopus 로고    scopus 로고
    • Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidaemia in diabetes
    • Phillips C, Anderton K, Bennett A et al. Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidaemia in diabetes. Metabolism 51, 847-852 (2002).
    • (2002) Metabolism , vol.51 , pp. 847-852
    • Phillips, C.1    Anderton, K.2    Bennett, A.3
  • 127
    • 33646826006 scopus 로고    scopus 로고
    • Lipid and lipoprotein dysregulation in insulin resistant states
    • Avramoglu RK, Basciano H, Adeli K. Lipid and lipoprotein dysregulation in insulin resistant states. Clin. Chim. Acta 368, 1-19 (2006).
    • (2006) Clin. Chim. Acta , vol.368 , pp. 1-19
    • Avramoglu, R.K.1    Basciano, H.2    Adeli, K.3
  • 128
    • 0141755321 scopus 로고    scopus 로고
    • Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: A model of insulin resistance and Type 2 diabetes
    • Zoltowska M, Ziv E, Delvin E et al. Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: a model of insulin resistance and Type 2 diabetes. Diabetes 52, 2539-2545 (2003).
    • (2003) Diabetes , vol.52 , pp. 2539-2545
    • Zoltowska, M.1    Ziv, E.2    Delvin, E.3
  • 129
    • 11144241636 scopus 로고    scopus 로고
    • Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: Studies in the fructose-fed Syrian Golden hamster
    • Lewis GF, Uffelman K, Naples M et al. Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian Golden hamster. Endocrinology 146, 247-255 (2005).
    • (2005) Endocrinology , vol.146 , pp. 247-255
    • Lewis, G.F.1    Uffelman, K.2    Naples, M.3
  • 130
    • 33744812746 scopus 로고    scopus 로고
    • Intestinal microsomal triglyceride transfer protein in Type 2 diabetic and non-diabetic subjects: The relationship to triglyceride-rich postprandial lipoprotein composition
    • Phillips C, Mullan K, Owens D, Tomkin GH. Intestinal microsomal triglyceride transfer protein in Type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition. Atherosclerosis 187, 57-64 (2006).
    • (2006) Atherosclerosis , vol.187 , pp. 57-64
    • Phillips, C.1    Mullan, K.2    Owens, D.3    Tomkin, G.H.4
  • 131
    • 77953486383 scopus 로고    scopus 로고
    • An intrinsic gut leptin melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption
    • Iqbal J, Li X, Chang BH et al. An intrinsic gut leptin melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption. J. Lipid Res. 51(7), 1929-1942 (2010).
    • (2010) J. Lipid Res. , vol.51 , Issue.7 , pp. 1929-1942
    • Iqbal, J.1    Li, X.2    Chang, B.H.3
  • 132
    • 67649117896 scopus 로고    scopus 로고
    • Native LDL-cholesterol mediated monocyte adhesion molecule overexpression is blocked by simvastatin
    • Serrano CV Jr, Pesaro AE, de Lemos JA et al. Native LDL-cholesterol mediated monocyte adhesion molecule overexpression is blocked by simvastatin. Cardiovasc. Drugs Ther. 3, 215-220 (2009).
    • (2009) Cardiovasc. Drugs Ther. , vol.3 , pp. 215-220
    • Serrano Jr., C.V.1    Pesaro, A.E.2    De Lemos, J.A.3
  • 133
    • 70349425845 scopus 로고    scopus 로고
    • Small dense LDL and VLDL predict common carotid artery IMT and elicit an inflammatory response in peripheral blood mononuclear and endothelial cells
    • Norata GD, Raselli S, Grigore L et al. Small dense LDL and VLDL predict common carotid artery IMT and elicit an inflammatory response in peripheral blood mononuclear and endothelial cells. Atherosclerosis 206, 556-562 (2009).
    • (2009) Atherosclerosis , vol.206 , pp. 556-562
    • Norata, G.D.1    Raselli, S.2    Grigore, L.3
  • 134
    • 24144481801 scopus 로고    scopus 로고
    • Activation of peripheral blood CD14+ monocytes occurs in diabetes
    • Cipolletta C, Ryan KE, Hanna EV, Trimble ER. Activation of peripheral blood CD14+ monocytes occurs in diabetes. Diabetes 54, 2779-2786 (2005).
    • (2005) Diabetes , vol.54 , pp. 2779-2786
    • Cipolletta, C.1    Ryan, K.E.2    Hanna, E.V.3    Trimble, E.R.4
  • 135
    • 0032966525 scopus 로고    scopus 로고
    • Glucose and free radicals impair the antioxidant properties of serum albumin
    • Bourdon E, Loreau N, Blache D. Glucose and free radicals impair the antioxidant properties of serum albumin. FASEB J. 13, 233-244 (1999).
    • (1999) FASEB J. , vol.13 , pp. 233-244
    • Bourdon, E.1    Loreau, N.2    Blache, D.3
  • 136
    • 0036721312 scopus 로고    scopus 로고
    • Low density lipoprotein can cause death of islet b-cells by its cellular uptake and oxidative modification
    • Cnop M, Hannaert JC, Grupping AY, Pipeleers DG. Low density lipoprotein can cause death of islet b-cells by its cellular uptake and oxidative modification. Endocrinology 143, 3449-3453 (2002).
    • (2002) Endocrinology , vol.143 , pp. 3449-3453
    • Cnop, M.1    Hannaert, J.C.2    Grupping, A.Y.3    Pipeleers, D.G.4
  • 137
    • 0037898380 scopus 로고    scopus 로고
    • Diabetic dyslipidaemia: From basic research to clinical practice
    • Taskinen MR. Diabetic dyslipidaemia: from basic research to clinical practice. Diabetologia 46, 733-749 (2003).
    • (2003) Diabetologia , vol.46 , pp. 733-749
    • Taskinen, M.R.1
  • 138
    • 35848940724 scopus 로고    scopus 로고
    • The clinical relevance of LDL size and subclasses modulation in patients with Type 2 diabetes
    • Rizzo M, Rini GB, Berneis K. The clinical relevance of LDL size and subclasses modulation in patients with Type 2 diabetes. Exp. Clin. Endocrinol. Diabetes 115, 477-482 (2007).
    • (2007) Exp. Clin. Endocrinol. Diabetes , vol.115 , pp. 477-482
    • Rizzo, M.1    Rini, G.B.2    Berneis, K.3
  • 139
    • 20444394398 scopus 로고    scopus 로고
    • Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes
    • Phillips C, Owens D, Mullan K, Tomkin GH. Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes. Atherosclerosis 181, 100-114 (2005).
    • (2005) Atherosclerosis , vol.181 , pp. 100-114
    • Phillips, C.1    Owens, D.2    Mullan, K.3    Tomkin, G.H.4
  • 140
    • 0142184423 scopus 로고    scopus 로고
    • Oxidative modification of triacylglycerol-rich lipoproteins
    • Young IS, McFarlane C, McEneny J. Oxidative modification of triacylglycerol-rich lipoproteins. Biochem. Soc. Trans. 31(Pt 5), 1062-1065 (2003).
    • (2003) Biochem. Soc. Trans. , vol.31 , Issue.PART 5 , pp. 1062-1065
    • Young, I.S.1    McFarlane, C.2    McEneny, J.3
  • 141
    • 33846988243 scopus 로고    scopus 로고
    • Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins
    • Lam TK, Gutierrez-Juarez R, Pocai A et al. Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins. Nat. Med. 13, 171-180 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 171-180
    • Lam, T.K.1    Gutierrez-Juarez, R.2    Pocai, A.3
  • 142
    • 77953232310 scopus 로고    scopus 로고
    • Coronary artery calcium and cardiovascular risk in diabetes
    • Elkeles RS. Coronary artery calcium and cardiovascular risk in diabetes. Atherosclerosis 210(2), 331-336 (2010).
    • (2010) Atherosclerosis , vol.210 , Issue.2 , pp. 331-336
    • Elkeles, R.S.1
  • 144
    • 0024561103 scopus 로고
    • Importance of small intestine in diabetic hypercholesterolemia
    • Feingold KR. Importance of small intestine in diabetic hypercholesterolemia. Diabetes 38, 141-145 (1989).
    • (1989) Diabetes , vol.38 , pp. 141-145
    • Feingold, K.R.1
  • 145
    • 0023074248 scopus 로고
    • A comparative study of the rate-limiting enzymes of cholesterol synthesis, esterification and catabolism in the alloxan-induced diabetic rat and rabbit
    • Devery R, O'Meara N, Collins P, Johnson A, Scott L, Tomkin GH. A comparative study of the rate-limiting enzymes of cholesterol synthesis, esterification and catabolism in the alloxan-induced diabetic rat and rabbit. Comp. Biochem. Physiol. 87b, 697-702 (1987).
    • (1987) Comp. Biochem. Physiol. , vol.87 B , pp. 697-702
    • Devery, R.1    O'Meara, N.2    Collins, P.3    Johnson, A.4    Scott, L.5    Tomkin, G.H.6
  • 146
    • 34848846093 scopus 로고    scopus 로고
    • Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of Type 1 diabetes: The effect of improved glycemic control
    • Sittiwet C, Gylling H, Hallikainen M et al. Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of Type 1 diabetes: the effect of improved glycemic control. Atherosclerosis 194, 465-472 (2007).
    • (2007) Atherosclerosis , vol.194 , pp. 465-472
    • Sittiwet, C.1    Gylling, H.2    Hallikainen, M.3
  • 147
    • 33746690405 scopus 로고    scopus 로고
    • Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with Type 2 diabetes
    • Matikainen N, Mänttäri S, Schweizer A et al. Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with Type 2 diabetes. Diabetologia 49, 2049-2057 (2006).
    • (2006) Diabetologia , vol.49 , pp. 2049-2057
    • Matikainen, N.1    Mänttäri, S.2    Schweizer, A.3
  • 148
    • 0025647276 scopus 로고
    • Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats
    • Feingold KR, Soued M, Adi S et al. Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats. Diabetes 39, 1569-1574 (1990).
    • (1990) Diabetes , vol.39 , pp. 1569-1574
    • Feingold, K.R.1    Soued, M.2    Adi, S.3
  • 149
    • 33745310797 scopus 로고    scopus 로고
    • Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: Evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine
    • Federico LM, Naples M, Taylor D, Adeli K. Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine. Diabetes 55, 1316-1326 (2006).
    • (2006) Diabetes , vol.55 , pp. 1316-1326
    • Federico, L.M.1    Naples, M.2    Taylor, D.3    Adeli, K.4
  • 150
    • 33847012545 scopus 로고    scopus 로고
    • Tumor necrosis factor-a induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins
    • Qin B, Qiu W, Avramoglu RK, Adeli K. Tumor necrosis factor-a induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes 56, 450-461 (2007).
    • (2007) Diabetes , vol.56 , pp. 450-461
    • Qin, B.1    Qiu, W.2    Avramoglu, R.K.3    Adeli, K.4
  • 152
    • 0034570331 scopus 로고    scopus 로고
    • The relationship between cholesterol absorption and intestinal cholesterol synthesis in the diabetic rat model
    • Gleeson A, Owens D, Collins P, Johnson A, Tomkin GH. The relationship between cholesterol absorption and intestinal cholesterol synthesis in the diabetic rat model. Int. J. Exp. Diabetes Res. 1, 203-210 (2000).
    • (2000) Int. J. Exp. Diabetes Res. , vol.1 , pp. 203-210
    • Gleeson, A.1    Owens, D.2    Collins, P.3    Johnson, A.4    Tomkin, G.H.5
  • 153
    • 26244453309 scopus 로고    scopus 로고
    • Proactive Investigators Secondary prevention of macrovascular events in patients with Type 2 diabetes in the Proactive Study (Prospective Pioglitazone Clinical Trial in Macrovascular Events): A randomised controlled trial
    • Dormandy JA, Charbonnel B, Eckland DJ et al.; Proactive Investigators. Secondary prevention of macrovascular events in patients with Type 2 diabetes in the Proactive Study (Prospective Pioglitazone Clinical Trial in Macrovascular Events): a randomised controlled trial. Lancet 366, 1279-1289 (2005).
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3
  • 154
    • 34548590934 scopus 로고    scopus 로고
    • Pioglitazone and risk of cardiovascular events in patients with Type 2 diabetes mellitus: A meta-analysis of randomized trials
    • Lincoff AM, Wolski K, Nicholls SJ, Nissen SE. Pioglitazone and risk of cardiovascular events in patients with Type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 298, 1180-1188 (2007).
    • (2007) JAMA , vol.298 , pp. 1180-1188
    • Lincoff, A.M.1    Wolski, K.2    Nicholls, S.J.3    Nissen, S.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.