메뉴 건너뛰기




Volumn 15, Issue 8, 2012, Pages 595-610

Application of NMR metabolomics to search for human disease biomarkers

Author keywords

Biomarkers; Cmultivariate statistics; Metabolomics; NMR

Indexed keywords

BIOLOGICAL MARKER;

EID: 84867250802     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/138620712802650522     Document Type: Article
Times cited : (120)

References (134)
  • 2
    • 33750105113 scopus 로고    scopus 로고
    • Science in Greece: From the age of Hippocrates to the age of the genome
    • Falagas, M. E. Science in Greece: from the age of Hippocrates to the age of the genome. FASEB J., 2006, 20 (12), 1946-1950.
    • (2006) Faseb J , vol.20 , Issue.12 , pp. 1946-1950
    • Falagas, M.E.1
  • 4
    • 84955496686 scopus 로고    scopus 로고
    • Metabonomics
    • Nicholson, J.K.; Lindon, J. C. Metabonomics. Nature, 2008, 455 (23), 1045-1056.
    • (2008) Nature , vol.455 , Issue.23 , pp. 1045-1056
    • Nicholson, J.K.1    Lindon, J.C.2
  • 5
    • 16844377775 scopus 로고    scopus 로고
    • A history of diabetes mellitus or how a disease of the kidneys evolved into a kidney disease
    • Eknoyan, G.; Nagy, J. A history of diabetes mellitus or how a disease of the kidneys evolved into a kidney disease. Adv. Chronic Kidney D., 2005, 12, (2), 223-229.
    • (2005) Adv. Chronic Kidney D , vol.12 , Issue.2 , pp. 223-229
    • Eknoyan, G.1    Nagy, J.2
  • 6
    • 76249085655 scopus 로고    scopus 로고
    • Clinical chemistry: Challenges for analytical chemistry and the nanosciences from medicine
    • Durner, J. Clinical chemistry: Challenges for analytical chemistry and the nanosciences from medicine. Angew. Chem., Int. Ed., 2009, 49 (6), 1026-1051.
    • (2009) Angew. Chem., Int. Ed , vol.49 , Issue.6 , pp. 1026-1051
    • Durner, J.1
  • 7
    • 0016203474 scopus 로고
    • Techniques of orthomolecular diagnosis
    • Robinson, B.; Pauling, L. Techniques of orthomolecular diagnosis. Clin. Chem., 1974, 20 (8), 961-965.
    • (1974) Clin. Chem , vol.20 , Issue.8 , pp. 961-965
    • Robinson, B.1    Pauling, L.2
  • 9
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics - The link between genotypes and phenotypes
    • Fiehn, O. Metabolomics - the link between genotypes and phenotypes. Plant Mol. Biol. 2002, 48 (1-2), 155-171.
    • (2002) Plant Mol. Biol , vol.48 , Issue.1-2 , pp. 155-171
    • Fiehn, O.1
  • 10
    • 0036787307 scopus 로고    scopus 로고
    • Beyond Mendel: An evolving view of human genetic disease transmission
    • Badano, J. L.; Katsanis, N. Beyond Mendel: an evolving view of human genetic disease transmission. Nat. Rev. Genet., 2002, 3 (10), 779-789.
    • (2002) Nat. Rev. Genet , vol.3 , Issue.10 , pp. 779-789
    • Badano, J.L.1    Katsanis, N.2
  • 11
    • 65849122374 scopus 로고    scopus 로고
    • Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers
    • Rebbeck, T. R.; Domchek, S. M. Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res., 2008, 10 (108).
    • (2008) Breast Cancer Res , vol.10 , Issue.108
    • Rebbeck, T.R.1    Domchek, S.M.2
  • 13
    • 79551598937 scopus 로고    scopus 로고
    • Therapeutic approaches for women predisposed to breast cancer
    • Nathanson, K. L.; Domchek, S. M. Therapeutic approaches for women predisposed to breast cancer. Annu. Rev. Med., 2011, 62, 295-306.
    • (2011) Annu. Rev. Med , vol.62 , pp. 295-306
    • Nathanson, K.L.1    Domchek, S.M.2
  • 14
    • 79953097676 scopus 로고    scopus 로고
    • Preserving the self: The process of decision making about hereditary breast cancer and ovarian cancer risk reduction
    • Howard, A. F.; Balneaves, L. G.; Bottorff, J. L.; Rodney, P. Preserving the self: the process of decision making about hereditary breast cancer and ovarian cancer risk reduction. Qual Health Res., 2011, 21 (4), 502-519.
    • (2011) Qual Health Res , vol.21 , Issue.4 , pp. 502-519
    • Howard, A.F.1    Balneaves, L.G.2    Bottorff, J.L.3    Rodney, P.4
  • 15
    • 82955167905 scopus 로고    scopus 로고
    • Proteomics in Parkinson's disease: An unbiased approach towards peripheral biomarkers and new therapies
    • Alberio, T.; Fasano, M. Proteomics in Parkinson's disease: An unbiased approach towards peripheral biomarkers and new therapies. J. Biotechnol., 2011, 156 (4), 325-337.
    • (2011) J. Biotechnol , vol.156 , Issue.4 , pp. 325-337
    • Alberio, T.1    Fasano, M.2
  • 16
    • 79961178546 scopus 로고    scopus 로고
    • Emerging and neglected tropical diseases: Translational application of proteomics
    • Denman, B.; Goodman, S. R. Emerging and neglected tropical diseases: translational application of proteomics. Exp. Biol. Med., 2011, 236 (8), 972-976.
    • (2011) Exp. Biol. Med , vol.236 , Issue.8 , pp. 972-976
    • Denman, B.1    Goodman, S.R.2
  • 17
    • 79952496444 scopus 로고    scopus 로고
    • Progress in mining the human proteome for disease applications
    • Hanash, S. Progress in mining the human proteome for disease applications. OMICS, 2011, 15 (3), 133-139.
    • (2011) Omics , vol.15 , Issue.3 , pp. 133-139
    • Hanash, S.1
  • 18
    • 0029815467 scopus 로고    scopus 로고
    • Glycosylation of microtubule-associated protein tau: An abnormal posttranslational modification in Alzheimer's disease
    • Wang, J.-Z.; Grundke-Iqbal, I.; Iqbal, K. Glycosylation of microtubule-associated protein tau: An abnormal posttranslational modification in Alzheimer's disease. Nature, 1996, 2 (8), 871-875.
    • (1996) Nature , vol.2 , Issue.8 , pp. 871-875
    • Wang, J.-Z.1    Grundke-Iqbal, I.2    Iqbal, K.3
  • 19
    • 79959539790 scopus 로고    scopus 로고
    • Ubiquitylation in apoptosis: A post-translational modification at the edge of life and death
    • Vucic, D.; Dixit, V. M.; Wertz, I. E. Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death. Nat. Rev. Mol. Cell Biol., 2011, 12 (7), 439-452.
    • (2011) Nat. Rev. Mol. Cell Biol , vol.12 , Issue.7 , pp. 439-452
    • Vucic, D.1    Dixit, V.M.2    Wertz, I.E.3
  • 20
    • 80053573543 scopus 로고    scopus 로고
    • Small changes, Big impact: Posttranslational modifications and function of huntingtin in huntington disease
    • Ehrnhoefer, D. E.; Sutton, L.; Hayden, M. R. Small changes, Big impact: posttranslational modifications and function of huntingtin in huntington disease. The Neuroscientist, 2011, 17 (5), 475-492.
    • (2011) The Neuroscientist , vol.17 , Issue.5 , pp. 475-492
    • Ehrnhoefer, D.E.1    Sutton, L.2    Hayden, M.R.3
  • 21
    • 71449127146 scopus 로고    scopus 로고
    • The proteomic profile of pancreatic cancer cell lines corresponding to carcinogenesis and metastasis
    • Yamada, M.; Fujii, K.; Koyama, K.; Hirohashi, S.; Kondo, T. The proteomic profile of pancreatic cancer cell lines corresponding to carcinogenesis and metastasis. J. Proteomics Bioinf., 2009, 2 (1), 001-018.
    • (2009) J. Proteomics Bioinf , vol.2 , Issue.1 , pp. 001-018
    • Yamada, M.1    Fujii, K.2    Koyama, K.3    Hirohashi, S.4    Kondo, T.5
  • 22
    • 10844252383 scopus 로고    scopus 로고
    • Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry
    • Shen, J.; Person, M. D.; Zhu, J.; Abbruzzese, J. L.; Li, D. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. Cancer Res., 2004, 64 (24), 9018-9026.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 9018-9026
    • Shen, J.1    Person, M.D.2    Zhu, J.3    Abbruzzese, J.L.4    Li, D.5
  • 28
    • 72249116728 scopus 로고    scopus 로고
    • NMR metabolomics and drug discovery
    • Powers, R. NMR metabolomics and drug discovery. Magn. Reson. Chem., 2009, 47 (S1), S2-S11.
    • (2009) Magn. Reson. Chem , vol.47 , Issue.S1
    • Powers, R.1
  • 29
    • 79959878069 scopus 로고    scopus 로고
    • Metabolomics, pathway regulation, and pathway discovery
    • Zhang, G.-F.; Sadhukhan, S.; Tochtrop, G. P.; Brunengraber, H. Metabolomics, pathway regulation, and pathway discovery. J. Biol. Chem., 2011, 286, (27), 23631-23635.
    • (2011) J. Biol. Chem , vol.286 , Issue.27 , pp. 23631-23635
    • Zhang, G.-F.1    Sadhukhan, S.2    Tochtrop, G.P.3    Brunengraber, H.4
  • 30
    • 0015131404 scopus 로고
    • Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography
    • Pauling, L.; Robinson, A. B.; Teranishit, R.; Cary, P. Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. Proc. Natl. Acad. Sci. U S A, 1971, 68 (10), 2374-2376.
    • (1971) Proc. Natl. Acad. Sci. U S A , vol.68 , Issue.10 , pp. 2374-2376
    • Pauling, L.1    Robinson, A.B.2    Teranishit, R.3    Cary, P.4
  • 33
    • 34047109055 scopus 로고    scopus 로고
    • Metabolomics of aquatic organisms: The new 'omics' on the block
    • Viant, M. R. Metabolomics of aquatic organisms: the new 'omics' on the block. Mar. Ecol. Prog. Ser., 2007, 332, 301-306.
    • (2007) Mar. Ecol. Prog. ser , vol.332 , pp. 301-306
    • Viant, M.R.1
  • 34
    • 61849165638 scopus 로고    scopus 로고
    • Environmental metabolomics: A critical review and future perspectives
    • Bundy, J. G.; Davey, M. P.; Viant, M. R. Environmental metabolomics: a critical review and future perspectives. Metabolomics, 2008, 5 (1), 3-21.
    • (2008) Metabolomics , vol.5 , Issue.1 , pp. 3-21
    • Bundy, J.G.1    Davey, M.P.2    Viant, M.R.3
  • 39
    • 79954416685 scopus 로고    scopus 로고
    • Advances in mass spectrometry applied to pharmaceutical metabolomics
    • Drexler, D. M.; Reily, M. D.; Shipkova, P. A. Advances in mass spectrometry applied to pharmaceutical metabolomics. Anal. Bioanal. Chem., 2011, 399, 2645-2653.
    • (2011) Anal. Bioanal. Chem , vol.399 , pp. 2645-2653
    • Drexler, D.M.1    Reily, M.D.2    Shipkova, P.A.3
  • 40
    • 78649810282 scopus 로고    scopus 로고
    • Metabolomics approach for investigation of effects of dengue virus infection using the EA.hy926 cell line
    • Birungi, G.; Meijie Chen, S.; Pheng Loy, B.; Lee Ng, M.; Fong Yau Li, S. Metabolomics approach for investigation of effects of dengue virus infection using the EA.hy926 cell line. J. Proteome Res., 2010, 9, 6523-6534.
    • (2010) J. Proteome Res , vol.9 , pp. 6523-6534
    • Birungi, G.1    Meijie Chen, S.2    Pheng Loy, B.3    Lee Ng, M.4    Fong Yau Li, S.5
  • 41
    • 13244264923 scopus 로고    scopus 로고
    • Metabolite fingerprinting and profiling in plants using NMR
    • Krishnan, P. Metabolite fingerprinting and profiling in plants using NMR. J. Exp. Bot., 2004, 56 (410), 255-265.
    • (2004) J. Exp. Bot , vol.56 , Issue.410 , pp. 255-265
    • Krishnan, P.1
  • 42
    • 33847352401 scopus 로고    scopus 로고
    • A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR- null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome
    • Atherton, H. J.; Bailey, N. J.; Zhang, W.; Taylor, J.; Major, H.; Shockcor, J.; Clarke, K.; Griffin, J. L. A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR- null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome. Physiol. Genomics, 2006, 27 (2), 178-186.
    • (2006) Physiol. Genomics , vol.27 , Issue.2 , pp. 178-186
    • Atherton, H.J.1    Bailey, N.J.2    Zhang, W.3    Taylor, J.4    Major, H.5    Shockcor, J.6    Clarke, K.7    Griffin, J.L.8
  • 43
    • 33846109344 scopus 로고    scopus 로고
    • Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics
    • Pan, Z.; Raftery, D. Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics. Anal. Bioanal. Chem., 2007, 387 (2), 525-527.
    • (2007) Anal. Bioanal. Chem , vol.387 , Issue.2 , pp. 525-527
    • Pan, Z.1    Raftery, D.2
  • 44
    • 80051665642 scopus 로고    scopus 로고
    • An 1H NMR and UPLC-MS-based plasma metabonomic study to investigate the biochemical changes in chronic unpredictable mild stress model of depression
    • Zheng, S.; Zhang, S.; Yu, M.; Tang, J.; Lu, X.; Wang, F.; Yang, J.; Li, F. An 1H NMR and UPLC-MS-based plasma metabonomic study to investigate the biochemical changes in chronic unpredictable mild stress model of depression. Metabolomics, 2011, 7 (3), 413-423.
    • (2011) Metabolomics , vol.7 , Issue.3 , pp. 413-423
    • Zheng, S.1    Zhang, S.2    Yu, M.3    Tang, J.4    Lu, X.5    Wang, F.6    Yang, J.7    Li, F.8
  • 46
    • 78651355465 scopus 로고    scopus 로고
    • Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer
    • Gu, H.; Pan, Z.; Xi, B.; Asiago, V.; Musselman, B.; Raftery, D. Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer. Anal. Chim. Acta, 2011, 686 (1-2), 57-63.
    • (2011) Anal. Chim. Acta , vol.686 , Issue.1-2 , pp. 57-63
    • Gu, H.1    Pan, Z.2    Xi, B.3    Asiago, V.4    Musselman, B.5    Raftery, D.6
  • 47
    • 0020645974 scopus 로고
    • High resolution 1H n.m.r. studies of vertebrate blood and plasma
    • Nicholson, J. K.; Buckingham, M. J.; Saldler, P. J. High resolution 1H n.m.r. studies of vertebrate blood and plasma. Biochem. J., 1983, 211 (3), 605-615.
    • (1983) Biochem. J , vol.211 , Issue.3 , pp. 605-615
    • Nicholson, J.K.1    Buckingham, M.J.2    Saldler, P.J.3
  • 48
    • 33846977711 scopus 로고    scopus 로고
    • Metabonomics in pharmaceutical R & D
    • Lindon, J. C.; Holmes, E.; Nicholson, J. K. Metabonomics in pharmaceutical R & D. FEBS J., 2007, 274 (5), 1140-1151.
    • (2007) Febs J , vol.274 , Issue.5 , pp. 1140-1151
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 50
    • 64949105863 scopus 로고    scopus 로고
    • Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1H NMR spectroscopy
    • Teng, R.; Junankar, P. R.; Bubb, W. A.; Rae, C.; Mercier, P.; Kirk, K. Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1H NMR spectroscopy. NMR Biomed., 2009, 22 (3), 292-302.
    • (2009) NMR Biomed , vol.22 , Issue.3 , pp. 292-302
    • Teng, R.1    Junankar, P.R.2    Bubb, W.A.3    Rae, C.4    Mercier, P.5    Kirk, K.6
  • 51
    • 77951454811 scopus 로고    scopus 로고
    • NMR-based analysis of metabolites in urine provides rapid diagnosis and etiology of pneumonia
    • Slupsky, C. M. NMR-based analysis of metabolites in urine provides rapid diagnosis and etiology of pneumonia. Biomarkers Med., 2010, 4 (2), 195-197.
    • (2010) Biomarkers Med , vol.4 , Issue.2 , pp. 195-197
    • Slupsky, C.M.1
  • 52
    • 79958856339 scopus 로고    scopus 로고
    • A Decade in prostate cancer: From NMR to metabolomics
    • DeFeo, E. M.; Wu, C.-L.; McDougal, W. S.; Cheng, L. L. A decade in prostate cancer: from NMR to metabolomics. Nat. Rev. Urol., 2011, 8 (6), 301-311.
    • (2011) Nat. Rev. Urol , vol.8 , Issue.6 , pp. 301-311
    • Defeo, E.M.1    Wu, C.-L.2    McDougal, W.S.3    Cheng, L.L.4
  • 53
    • 68949110561 scopus 로고    scopus 로고
    • Metabolic profiling of Parkinson's disease: Evidence of biomarker from gene expression analysis and rapid neural network detection
    • Ahmed, S. S. S. J.; Santosh, W.; Kumar, S.; Christlet, H. Metabolic profiling of Parkinson's disease: evidence of biomarker from gene expression analysis and rapid neural network detection. J. Biomed. Sci., 2009, 16, 63.
    • (2009) J. Biomed. Sci , vol.16 , pp. 63
    • Ahmed, S.S.S.J.1    Santosh, W.2    Kumar, S.3    Christlet, H.4
  • 54
    • 77149179378 scopus 로고    scopus 로고
    • NMR-based metabolomic analysis of cerebrospinal fluid and serum in neurological diseases - A diagnostic tool?
    • Sinclair, A. J.; Viant, M. R.; Ball, A. K.; Burdon, M. A.; Walker, E. A.; Stewart, P. M.; Rauz, S.; Young, S. P. NMR-based metabolomic analysis of cerebrospinal fluid and serum in neurological diseases - a diagnostic tool? NMR Biomed., 2009, 23 (2), 123-132.
    • (2009) NMR Biomed , vol.23 , Issue.2 , pp. 123-132
    • Sinclair, A.J.1    Viant, M.R.2    Ball, A.K.3    Burdon, M.A.4    Walker, E.A.5    Stewart, P.M.6    Rauz, S.7    Young, S.P.8
  • 55
    • 33749165575 scopus 로고    scopus 로고
    • Metabonomic models of human pancreatic cancer using 1D proton NMR spectra of lipids in plasma
    • Beger, R. D.; Schnackenberg, L. K.; Holland, R. D.; Li, D.; Dragan, Y. Metabonomic models of human pancreatic cancer using 1D proton NMR spectra of lipids in plasma. Metabolomics, 2006, 2 (3), 125-134.
    • (2006) Metabolomics , vol.2 , Issue.3 , pp. 125-134
    • Beger, R.D.1    Schnackenberg, L.K.2    Holland, R.D.3    Li, D.4    Dragan, Y.5
  • 59
    • 31344450644 scopus 로고    scopus 로고
    • Metabolic profiling using principal component analysis, discriminant partial least squares, and genetic algorithms
    • Ramadan, Z.; Jacobs, D.; Grigorov, M.; Kochhar, S. Metabolic profiling using principal component analysis, discriminant partial least squares, and genetic algorithms. Talanta, 2006, 68 (5), 1683-1691.
    • (2006) Talanta , vol.68 , Issue.5 , pp. 1683-1691
    • Ramadan, Z.1    Jacobs, D.2    Grigorov, M.3    Kochhar, S.4
  • 60
    • 64949194229 scopus 로고    scopus 로고
    • Metabolite profiling of fecal water extracts from human colorectal cancer
    • Monleón, D.; Morales, J. M.; Barrasa, A.; López, J. A.; Vázquez, C.; Celda, B. Metabolite profiling of fecal water extracts from human colorectal cancer. NMR Biomed., 2009, 22 (3), 342-348.
    • (2009) NMR Biomed , vol.22 , Issue.3 , pp. 342-348
    • Monleón, D.1    Morales, J.M.2    Barrasa, A.3    López, J.A.4    Vázquez, C.5    Celda, B.6
  • 61
    • 80052961525 scopus 로고    scopus 로고
    • Metabolomics and preterm birth: What biomarkers in cervicovaginal secretions are predictive of high-risk pregnant women?
    • Auray-Blais, C.; Raiche, E.; Gagnon, R.; Berthiaume, M.; Pasquier, J.-C. Metabolomics and preterm birth: What biomarkers in cervicovaginal secretions are predictive of high-risk pregnant women? International J. Mass Spectrom., 2011, 307 (1-3), 33-38.
    • (2011) International J. Mass Spectrom , vol.307 , Issue.1-3 , pp. 33-38
    • Auray-Blais, C.1    Raiche, E.2    Gagnon, R.3    Berthiaume, M.4    Pasquier, J.-C.5
  • 62
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert, O.; Keun, H. C.; Ebbels, T. M. D.; Bundy, J.; Holmes, E.; Lindon, J. C.; Nicholson, J. K. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc., 2007, 2 (11), 2692-2703.
    • (2007) Nat. Protoc , vol.2 , Issue.11 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.D.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6    Nicholson, J.K.7
  • 63
  • 65
    • 60849139445 scopus 로고    scopus 로고
    • Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR spectroscopy and gas chromatography mass spectrometry (GC/MS)
    • Chan, E. C. Y.; Koh, P. K.; Mal, M.; Cheah, P. Y.; Eu, K. W.; Backshall, A.; Cavill, R.; Nicholson, J. K.; Keun, H. C. Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR spectroscopy and gas chromatography mass spectrometry (GC/MS). J. Proteome Res., 2009, 8 (1), 352-361.
    • (2009) J. Proteome Res , vol.8 , Issue.1 , pp. 352-361
    • Chan, C.E.Y.1    Koh, P.K.2    Mal, M.3    Cheah, P.Y.4    Eu, K.W.5    Backshall, A.6    Cavill, R.7    Nicholson, J.K.8    Keun, H.C.9
  • 66
  • 67
    • 59449097019 scopus 로고    scopus 로고
    • Clinical applications of metabolomics in oncology: A Review
    • Spratlin, J. L.; Serkova, N. J.; Eckhardt, S. G. Clinical applications of metabolomics in oncology: A Review. Clin. Cancer Res., 2009, 15, 431-440.
    • (2009) Clin. Cancer Res , vol.15 , pp. 431-440
    • Spratlin, J.L.1    Serkova, N.J.2    Eckhardt, S.G.3
  • 68
    • 33947392610 scopus 로고    scopus 로고
    • Urine stability for metabolomic studies: Effects of preparation and storage
    • Saude, E. J.; Sykes, B. D. Urine stability for metabolomic studies: effects of preparation and storage. Metabolomics, 2007, 3 (1), 19-27.
    • (2007) Metabolomics , vol.3 , Issue.1 , pp. 19-27
    • Saude, E.J.1    Sykes, B.D.2
  • 69
    • 34547190179 scopus 로고    scopus 로고
    • Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies
    • Anthony D. Maher, A.D.; Zirah, S.F.M.; Holmes, E.; Nicholsen J.K. Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies. Anal. Chem., 2007, 79 (14), 5204-5211.
    • (2007) Anal. Chem , vol.79 , Issue.14 , pp. 5204-5211
    • Anthony Maher, A.D.D.1    Zirah, F.S.M.2    Holmes, E.3    Nicholsen, J.K.4
  • 73
    • 84867264005 scopus 로고    scopus 로고
    • NCCLS, urinalysis and collection, transportation, and preservation of urine specimens
    • Approved Guideline-Second Edition, NCCLS, 940 West Valley Rd, Suite 1400, Wayne, Pennsylvania USA
    • NCCLS, Urinalysis and Collection, Transportation, and Preservation of Urine Specimens; Approved Guideline-Second Edition. NCCLS document GP16-A2 [ISBN 1-56238-448-1], NCCLS, 940 West Valley Rd, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2001.
    • (2001) NCCLS Document GP16-A2 [ISBN 1-56238-448-1] , pp. 19087-21898
  • 74
    • 33846986484 scopus 로고    scopus 로고
    • Human urine as test material in 1H NMR-based metabonomics: Recommendations for sample preparation and storage
    • Lauridsen, M.; Hansen, S. H.; Jroszewski, J. W.; Cornett, C. Human urine as test material in 1H NMR-based metabonomics: Recommendations for sample preparation and storage. Anal. Chem., 2007, 79 (3), 1181-1186.
    • (2007) Anal. Chem , vol.79 , Issue.3 , pp. 1181-1186
    • Lauridsen, M.1    Hansen, S.H.2    Jroszewski, J.W.3    Cornett, C.4
  • 76
    • 72749126091 scopus 로고    scopus 로고
    • Effects of a prolonged standardized diet on normalizing the human metabolome. Am
    • Winnike, J. H.; Busby, M. G.; Watkins, P. B.; O'Connell, T. M. Effects of a prolonged standardized diet on normalizing the human metabolome. Am. J. Clin. Nutr., 2009, 90 (6), 1496-1501.
    • (2009) J. Clin. Nutr , vol.90 , Issue.6 , pp. 1496-1501
    • Winnike, J.H.1    Busby, M.G.2    Watkins, P.B.3    O'Connell, T.M.4
  • 80
    • 79958771235 scopus 로고    scopus 로고
    • Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks
    • Bernini, P.; Bertini, I.; Luchinat, C.; Nincheri, P.; Staderini, S.; Turano, P. Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks. J. Biomol. NMR, 2011, 49 (3-4), 231-243.
    • (2011) J. Biomol. NMR , vol.49 , Issue.3-4 , pp. 231-243
    • Bernini, P.1    Bertini, I.2    Luchinat, C.3    Nincheri, P.4    Staderini, S.5    Turano, P.6
  • 82
    • 0026634841 scopus 로고
    • Circadian modulation of glucose and insulin responses to meals: Relationship to cortisol rhythm
    • Van, C. E.; Shapiro, E. T.; Tillil, H.; Polonsky, K. S. Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythm. Am. J. Physiol., 1992, 262 (4, Pt. 1), E467- E475.
    • (1992) Am. J. Physiol , vol.262 , Issue.4
    • Van, C.E.1    Shapiro, E.T.2    Tillil, H.3    Polonsky, K.S.4
  • 84
    • 34248400811 scopus 로고    scopus 로고
    • The increasing importance of inflammation in neurological disease
    • Bone, I. The increasing importance of inflammation in neurological disease. Curr. Opin. Neurol., 2007, 20, (3), 331-333.
    • (2007) Curr. Opin. Neurol , vol.20 , Issue.3 , pp. 331-333
    • Bone, I.1
  • 85
    • 0021403120 scopus 로고
    • Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine
    • Bales, J. R.; P. Higham, D.; Howe, I.; Nicholson, J. K.; Sadler, P. J. Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine. Clin. Chem., 1984, 30 (3), 426-432.
    • (1984) Clin. Chem , vol.30 , Issue.3 , pp. 426-432
    • Bales, J.R.1    Higham, D.P.2    Howe, I.3    Nicholson, J.K.4    Sadler, P.J.5
  • 87
    • 79959950881 scopus 로고    scopus 로고
    • Metabolomic approach by1H NMR spectroscopy of serum for the assessment of chronic liver failure in patients with cirrhosis
    • Amathieu, R.; Nahon, P.; Triba, M.; Bouchemal, N.; Trinchet, J.- C.; Beaugrand, M.; Dhonneur, G.; Le Moyec, L. Metabolomic approach by1H NMR spectroscopy of serum for the assessment of chronic liver failure in patients with cirrhosis. J. Proteome Res., 2011, 10 (7), 3239-3245.
    • (2011) J. Proteome Res , vol.10 , Issue.7 , pp. 3239-3245
    • Amathieu, R.1    Nahon, P.2    Triba, M.3    Bouchemal, N.4    Trinchet -, J.C.5    Beaugrand, M.6    Dhonneur, G.7    Le Moyec, L.8
  • 88
    • 78751581701 scopus 로고    scopus 로고
    • 1H-NMR-based metabolomics of tumor tissue for the metabolic characterization of rat hepatocellular carcinoma formation and metastasis
    • Wang, J.; Zhang, S.; Li, Z.; Yang, J.; Huang, C.; Liang, R.; Liu, Z.; Zhou, R. 1H-NMR-based metabolomics of tumor tissue for the metabolic characterization of rat hepatocellular carcinoma formation and metastasis. Tumor Biol., 2010, 32 (1), 223-231.
    • (2010) Tumor Biol , vol.32 , Issue.1 , pp. 223-231
    • Wang, J.1    Zhang, S.2    Li, Z.3    Yang, J.4    Huang, C.5    Liang, R.6    Liu, Z.7    Zhou, R.8
  • 89
    • 79651471472 scopus 로고    scopus 로고
    • 1H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure
    • Kang, S.-M.; Park, J.-C.; Shin, M.-J.; Lee, H.; Oh, J.; Ryu, D. H.; Hwang, G.-S.; Chung, J. H. 1H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure. Clin. Biochem., 2011, 44 (4), 293-299.
    • (2011) Clin. Biochem , vol.44 , Issue.4 , pp. 293-299
    • Kang, S.-M.1    Park, J.-C.2    Shin, M.-J.3    Lee, H.4    Oh, J.5    Ryu, D.H.6    Hwang, G.-S.7    Chung, J.H.8
  • 95
    • 84855477382 scopus 로고    scopus 로고
    • Comparison of serum metabolite compositions between obese and lean growing pigs using an NMRbased metabonomic approach
    • He, Q.; Ren, P.; Kong, X.; Wu, Y.; Wu, G.; Li, P.; Hao, F.; Tang, H.; Blachier, F.; Yin, Y. Comparison of serum metabolite compositions between obese and lean growing pigs using an NMRbased metabonomic approach. J. Nutr. Biochemistry, 2011, 23 (2), 133-139.
    • (2011) J. Nutr. Biochemistry , vol.23 , Issue.2 , pp. 133-139
    • He, Q.1    Ren, P.2    Kong, X.3    Wu, Y.4    Wu, G.5    Li, P.6    Hao, F.7    Tang, H.8    Blachier, F.9    Yin, Y.10
  • 96
    • 70349921763 scopus 로고    scopus 로고
    • Seeing through macromolecules: T2-filtered NMR for the purity assay of functionalized nanosystems and the screening of biofluids
    • Rastrelli, F.; Jha, S.; Mancin, F. Seeing through macromolecules: T2-filtered NMR for the purity assay of functionalized nanosystems and the screening of biofluids. J. Am. Chem. Soc., 2009, 131, 14222-14224.
    • (2009) J. Am. Chem. Soc , vol.131 , pp. 14222-14224
    • Rastrelli, F.1    Jha, S.2    Mancin, F.3
  • 98
    • 37249067514 scopus 로고    scopus 로고
    • Method for determining molar concentrations of metabolites in complex solutions from two-dimensional 1H-13C NMR spectra
    • Lewis, I. A.; Schommer, S. C.; Hodis, B.; Robb, K. A.; Tonelli, M.; Westler, W. M.; Sussman, M. R.; Markley, J. L. Method for determining molar concentrations of metabolites in complex solutions from two-dimensional 1H-13C NMR spectra. Anal. Chem., 2007, 79, 9385-9390.
    • (2007) Anal. Chem , vol.79 , pp. 9385-9390
    • Lewis, I.A.1    Schommer, S.C.2    Hodis, B.3    Robb, K.A.4    Tonelli, M.5    Westler, W.M.6    Sussman, M.R.7    Markley, J.L.8
  • 99
    • 84858162581 scopus 로고    scopus 로고
    • NMR experiments for the analysis of mixtures: Beyond 1D 1H spectra
    • Jeannerat, D.; Furrer, J. NMR experiments for the analysis of mixtures: Beyond 1D 1H spectra. Comb. Chem. High Throughput Screen., 2012, 15 (1), 15-35.
    • (2012) Comb. Chem. High Throughput Screen , vol.15 , Issue.1 , pp. 15-35
    • Jeannerat, D.1    Furrer, J.2
  • 100
    • 54749118571 scopus 로고    scopus 로고
    • Self-consistent metabolic mixture analysis by heteronuclear NMR. application to a human cancer cell line
    • Zhang, F.; Bruschweiler-Li, L.; Robinette, S. L. Self-consistent metabolic mixture analysis by heteronuclear NMR. application to a human cancer cell line. Anal. Chem., 2008, 80 (19), 7549-7553.
    • (2008) Anal. Chem , vol.80 , Issue.19 , pp. 7549-7553
    • Zhang, F.1    Bruschweiler-Li, L.2    Robinette, S.L.3
  • 101
    • 68549085318 scopus 로고    scopus 로고
    • Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotoperesolved metabolomics (SIRM
    • Fan, T. W. M.; Lane, A. N.; Higashi, R. M.; Farag, M. A.; Gao, H.; Bousamra, M.; Miller, D. M. Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotoperesolved metabolomics (SIRM). Mol. Cancer, 2009, 8, 41.
    • (2009) Mol. Cancer , vol.8 , pp. 41
    • Fan, T.W.M.1    Lane, A.N.2    Higashi, R.M.3    Farag, M.A.4    Gao, H.5    Bousamra, M.6    Miller, D.M.7
  • 103
    • 0042627296 scopus 로고    scopus 로고
    • Quantitative 2D HSQC (Q-HSQC) via suppression of Jdependence of polarization transfer in NMR spectroscopy: Application to wood lignin
    • Heikkinen, S.; Toikka, M. M.; Karhunen, P. T.; Kilpeläinen, I. A. Quantitative 2D HSQC (Q-HSQC) via suppression of Jdependence of polarization transfer in NMR spectroscopy: Application to wood lignin. J. Am. Chem. Soc., 2003, 125 (14), 4362-4367.
    • (2003) J. Am. Chem. Soc , vol.125 , Issue.14 , pp. 4362-4367
    • Heikkinen, S.1    Toikka, M.M.2    Karhunen, P.T.3    Kilpelainen, I.A.4
  • 104
    • 1642335207 scopus 로고    scopus 로고
    • Sensitivity-enhanced quantitative 13C NMR spectroscopy via cancellation of 1JCH dependence in DEPT polarization transfers
    • Henderson, T. J. Sensitivity-enhanced quantitative 13C NMR spectroscopy via cancellation of 1JCH dependence in DEPT polarization transfers. J. Am. Chem. Soc., 2004, 126, 3682-3683.
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 3682-3683
    • Henderson, T.J.1
  • 107
    • 34250618834 scopus 로고    scopus 로고
    • Nondestructive quantification of organic compounds in whole milk without pretreatment by two-dimensional NMR spectroscopy
    • Hu, F.; Furihata, K.; Kato, Y.; Tanokura, M. Nondestructive quantification of organic compounds in whole milk without pretreatment by two-dimensional NMR spectroscopy. J. Agric. Food Chem., 2007, 55, 4307-4311.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 4307-4311
    • Hu, F.1    Furihata, K.2    Kato, Y.3    Tanokura, M.4
  • 108
    • 72149089299 scopus 로고    scopus 로고
    • Quantitative two-dimensional HSQC experiment for high magnetic field NMR spectrometers
    • Koskela, H.; Heikkilä, O.; Kilpeläinen, I.; Heikkinen, S. Quantitative two-dimensional HSQC experiment for high magnetic field NMR spectrometers. J. Magn. Reson., 2010, 202 (1), 24-33.
    • (2010) J. Magn. Reson , vol.202 , Issue.1 , pp. 24-33
    • Koskela, H.1    Heikkilä, O.2    Kilpeläinen, I.3    Heikkinen, S.4
  • 109
    • 79951533289 scopus 로고    scopus 로고
    • Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero1H-13C HSQC (HSQC0
    • Hu, K.; Westler, W. M.; Markley, J. L. Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero1H-13C HSQC (HSQC0). J. Amer. Chem. Soc., 2011, 133 (6), 1662-1665.
    • (2011) J. Amer. Chem. Soc , vol.133 , Issue.6 , pp. 1662-1665
    • Hu, K.1    Westler, W.M.2    Markley, J.L.3
  • 110
    • 41149120469 scopus 로고    scopus 로고
    • Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery
    • Lindon, J. C.; Nicholson, J. K. Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery. TrAC Trends in Anal. Chem., 2008, 27 (3), 194-204.
    • (2008) TrAC Trends in Anal. Chem , vol.27 , Issue.3 , pp. 194-204
    • Lindon, J.C.1    Nicholson, J.K.2
  • 111
    • 34548490763 scopus 로고    scopus 로고
    • Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation
    • Parsons, H. M.; Ludwig, C.; Günther, U. L.; Viant, M. R. Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation. BMC Bioinformatics, 2007, 8, 234.
    • (2007) BMC Bioinformatics , vol.8 , pp. 234
    • Parsons, H.M.1    Ludwig, C.2    Günther, U.L.3    Viant, M.R.4
  • 112
    • 0035796127 scopus 로고    scopus 로고
    • Pattern recognition methods and applications in biomedical magnetic resonance
    • Lindon, J. C.; Holmes, E.; Nicholson, J. K. Pattern recognition methods and applications in biomedical magnetic resonance. Prog. Nucl. Magn. Reson. Spectrosc., 2001, 39 (1), 1-40.
    • (2001) Prog. Nucl. Magn. Reson. Spectrosc , vol.39 , Issue.1 , pp. 1-40
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 113
    • 34249335649 scopus 로고    scopus 로고
    • OPLS discriminant analysis: Combining the strengths of PLS-DA and SIMCA classification
    • Bylesjoe, M.; Rantalainen, M.; Cloarec, O.; Nicholson, J. K.; Holmes, E.; Trygg, J. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification. J. Chemom., 2007, 20, 341-351.
    • (2007) J. Chemom , vol.20 , pp. 341-351
    • Bylesjoe, M.1    Rantalainen, M.2    Cloarec, O.3    Nicholson, J.K.4    Holmes, E.5    Trygg, J.6
  • 114
    • 0032517858 scopus 로고    scopus 로고
    • The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine
    • Holmes, E.; Nicholson, J. K.; Nicholls, A. W.; Lindon, J. C.; Connor, S. C.; Polley, S.; Connelly, J. The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine. Chemom. Intell. Lab. Syst., 1998, 44, 245-255.
    • (1998) Chemom. Intell. Lab. Syst , vol.44 , pp. 245-255
    • Holmes, E.1    Nicholson, J.K.2    Nicholls, A.W.3    Lindon, J.C.4    Connor, S.C.5    Polley, S.6    Connelly, J.7
  • 116
    • 33645663178 scopus 로고    scopus 로고
    • Scaling and normalization effects in NMR spectroscopic metabonomic data sets
    • Craig, A.; Cloarec, O.; Holmes, E.; Nicholson, J. K.; Lindon, J. C. Scaling and normalization effects in NMR spectroscopic metabonomic data sets. Anal. Chem., 2006, 78, 2262-2267.
    • (2006) Anal. Chem , vol.78 , pp. 2262-2267
    • Craig, A.1    Cloarec, O.2    Holmes, E.3    Nicholson, J.K.4    Lindon, J.C.5
  • 117
    • 28844433017 scopus 로고    scopus 로고
    • Negative impact of noise on the principal component analysis of NMR data
    • Halouska, S.; Powers, R. Negative impact of noise on the principal component analysis of NMR data. J. Magn. Reson., 2006, 178 (1)
    • (2006) J. Magn. Reson , vol.178 , Issue.1
    • Halouska, S.1    Powers, R.2
  • 118
    • 79251497689 scopus 로고    scopus 로고
    • Metabolomic profiling with NMR discriminates between biphosphonate and doxorubicin effects on B16 melanoma cells
    • Triba, M. N.; Starzec, A.; Bouchemal, N.; Guenin, E.; Perret, G. Y.; Le Moyec, L. Metabolomic profiling with NMR discriminates between biphosphonate and doxorubicin effects on B16 melanoma cells. NMR Biomed., 2010, 23 (9), 1009-1016.
    • (2010) NMR Biomed , vol.23 , Issue.9 , pp. 1009-1016
    • Triba, M.N.1    Starzec, A.2    Bouchemal, N.3    Guenin, E.4    Perret, G.Y.5    Le Moyec, L.6
  • 119
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations: Improving the biological information content of metabolomics data
    • van den Berg, R. A.; Hoefsloot, H. C. J.; Westerhuis, J. A.; Smilde, A. K.; van der Werf, M. J. Centering, scaling, and transformations: improving the biological information content of metabolomics data. BMC Genomics, 2006, 7, 142.
    • (2006) BMC Genomics , vol.7 , pp. 142
    • Van Den Berg, R.A.1    Hoefsloot, C.H.J.2    Westerhuis, J.A.3    Smilde, A.K.4    Van Der Werf, M.J.5
  • 121
    • 77949308124 scopus 로고    scopus 로고
    • Multivariate paired data analysis: Multilevel PLSDA versus OPLSDA
    • Westerhuis, J. A.; Velzen, E. J. J.; Hoefsloot, H. C. J.; Smilde, A. K. Multivariate paired data analysis: multilevel PLSDA versus OPLSDA. Metabolomics, 2009, 6 (1), 119-128.
    • (2009) Metabolomics , vol.6 , Issue.1 , pp. 119-128
    • Westerhuis, J.A.1    Velzen, E.J.J.2    Hoefsloot, H.C.J.3    Smilde, A.K.4
  • 122
    • 70350380194 scopus 로고    scopus 로고
    • Successful application of OPLS-DA for the discrimination of wild-type and mutated cells in acute lymphoblastic leukemia
    • Molteni, C. G.; Cazzaniga, G.; Condorelli, D. F.; Fortuna, C. G.; Biondi, A.; Musumarra, G. Successful application of OPLS-DA for the discrimination of wild-type and mutated cells in acute lymphoblastic leukemia. QSAR Comb. Sci., 2009, 28 (8), 822-828.
    • (2009) QSAR Comb. Sci , vol.28 , Issue.8 , pp. 822-828
    • Molteni, C.G.1    Cazzaniga, G.2    Condorelli, D.F.3    Fortuna, C.G.4    Biondi, A.5    Musumarra, G.6
  • 123
    • 77951124857 scopus 로고    scopus 로고
    • Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression
    • Basant, A.; Rege, M.; Sharma, S.; Sonawat, H. M. Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression. Malaria J., 2010, 9, 110.
    • (2010) Malaria J , vol.9 , pp. 110
    • Basant, A.1    Rege, M.2    Sharma, S.3    Sonawat, H.M.4
  • 125
    • 0029982849 scopus 로고    scopus 로고
    • Bootstrap confidence levels for phylogenetic trees
    • Efron, B.; Halloran, E.; Holmes, S. Bootstrap confidence levels for phylogenetic trees. Proc. Natl. Acad. Sci. U S A, 1996, 93 (23), 13429-13434.
    • (1996) Proc. Natl. Acad. Sci. U S A , vol.93 , Issue.23 , pp. 13429-13434
    • Efron, B.1    Halloran, E.2    Holmes, S.3
  • 127
    • 0033990046 scopus 로고    scopus 로고
    • Phylogenetic analysis using PHYLIP
    • Retief, J. D. Phylogenetic analysis using PHYLIP. Methods Mol. Biol., 2000, 132, 243-258.
    • (2000) Methods Mol. Biol , vol.132 , pp. 243-258
    • Retief, J.D.1
  • 129
    • 84856162572 scopus 로고    scopus 로고
    • Predicting the in vivo mechanism of action for drug leads using NMR metabolomics
    • Halouska, S.; Fenton, R. J.; Barletta, R. l. G.; Powers, R. Predicting the in vivo mechanism of action for drug leads using NMR metabolomics. ACS Chem. Biol., 2012, 7 (1), 166-171.
    • (2012) ACS Chem. Biol , vol.7 , Issue.1 , pp. 166-171
    • Halouska, S.1    Fenton, R.J.2    Barletta, R.L.G.3    Powers, R.4
  • 133
    • 80655131103 scopus 로고    scopus 로고
    • The cardiovascular risk of healthy individuals studied by NMR metabonomics of plasma samples
    • Bernini, P.; Bertini, I.; Luchinat, C.; Tenori, L.; Tognaccini, A. The cardiovascular risk of healthy individuals studied by NMR metabonomics of plasma samples. J. Proteome Res., 2011, 10 (11), 4983-4992.
    • (2011) J. Proteome Res , vol.10 , Issue.11 , pp. 4983-4992
    • Bernini, P.1    Bertini, I.2    Luchinat, C.3    Tenori, L.4    Tognaccini, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.