-
1
-
-
12444279265
-
On the origin of cancer cells
-
13298683
-
Warburg O On the origin of cancer cells Science 1956, 123:309-314. 13298683
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
2
-
-
0037108709
-
High expression of inducible 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers
-
12384552
-
Atsumi T Chesney J Metz C Leng L Donnelly S Makita Z Mitchell R Bucala R High expression of inducible 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers Cancer Research 2002, 62:5881-5887. 12384552
-
(2002)
Cancer Research
, vol.62
, pp. 5881-5887
-
-
Atsumi, T.1
Chesney, J.2
Metz, C.3
Leng, L.4
Donnelly, S.5
Makita, Z.6
Mitchell, R.7
Bucala, R.8
-
3
-
-
0345686721
-
Protein profiles associated with survival in lung adenocarcinoma
-
263849 14573703
-
Chen GA Gharib TG Wang H Huang CC Kuick R Thomas DG Shedden KA Misek DE Taylor JMG Giordano TJ Protein profiles associated with survival in lung adenocarcinoma Proceedings of the National Academy of Sciences of the United States of America 2003, 100:13537-13542. 263849 14573703
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 13537-13542
-
-
Chen, G.A.1
Gharib, T.G.2
Wang, H.3
Huang, C.C.4
Kuick, R.5
Thomas, D.G.6
Shedden, K.A.7
Misek, D.E.8
Taylor, J.M.G.9
Giordano, T.J.10
-
4
-
-
0033585463
-
Hexokinase type II: A novel tumor-specific promoter for gene-targeted therapy differentially expressed and regulated in human cancer cells
-
10022541 10022541
-
Katabi MM Chan HLB Karp SE Batist G Hexokinase type II: A novel tumor-specific promoter for gene-targeted therapy differentially expressed and regulated in human cancer cells Human Gene Therapy 1999, 10:155-164. 10022541
-
(1999)
Human Gene Therapy
, vol.10
, pp. 155-164
-
-
Katabi, M.M.1
Chan, H.L.B.2
Karp, S.E.3
Batist, G.4
-
5
-
-
0344197042
-
Lactate dehydrogenase isoenzymes 1 and 5: Differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors
-
14654714
-
Koukourakis MI Giatromanolaki A Sivridis E Lactate dehydrogenase isoenzymes 1 and 5: Differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors Tumor Biology 2003, 24:199-202. 14654714
-
(2003)
Tumor Biology
, vol.24
, pp. 199-202
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
-
6
-
-
13444272912
-
Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stromal
-
1490315 15736311
-
Koukourakis MI Giatromanolaki A Sivridis E Gatter KC Harris AL Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stromal Neoplasia 2005, 7:1-6. 1490315 15736311
-
(2005)
Neoplasia
, vol.7
, pp. 1-6
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Gatter, K.C.4
Harris, A.L.5
-
7
-
-
10744221423
-
Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer
-
1223948 14683524
-
Isidoro A Martinez M Fernandez PL Ortega AD Santamaria G Chamorro M Reed JC Cuezva JM Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer Biochemical Journal 2004, 378:17-20. 1223948 14683524
-
(2004)
Biochemical Journal
, vol.378
, pp. 17-20
-
-
Isidoro, A.1
Martinez, M.2
Fernandez, P.L.3
Ortega, A.D.4
Santamaria, G.5
Chamorro, M.6
Reed, J.C.7
Cuezva, J.M.8
-
8
-
-
0842312546
-
Comparison of F-18 fluorodeoxyglucose uptake with glucose transporter-1 expression and proliferation rate in human glioma and non-small-cell lung cancer
-
15061260
-
Chung JK Lee YJ Kim SK Jeong JM Lee DS Lee MC Comparison of F-18 fluorodeoxyglucose uptake with glucose transporter-1 expression and proliferation rate in human glioma and non-small-cell lung cancer Nuclear Medicine Communications 2004, 25:11-17. 15061260
-
(2004)
Nuclear Medicine Communications
, vol.25
, pp. 11-17
-
-
Chung, J.K.1
Lee, Y.J.2
Kim, S.K.3
Jeong, J.M.4
Lee, D.S.5
Lee, M.C.6
-
10
-
-
55949125948
-
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes
-
2577687 18939998
-
Fan T Kucia M Jankowski K Higashi R Ratajczak J Ratajczak M Lane A Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes Molecular Cancer 2008, 7:79. 2577687 18939998
-
(2008)
Molecular Cancer
, vol.7
, pp. 79
-
-
Fan, T.1
Kucia, M.2
Jankowski, K.3
Higashi, R.4
Ratajczak, J.5
Ratajczak, M.6
Lane, A.7
-
12
-
-
0027361294
-
Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon (1-13C)glucose incubation
-
7901007
-
Portais J-C Schuster R Merle M Canioni P Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon (1-13C)glucose incubation European Journal of Biochemistry 1993, 217:457-468. 7901007
-
(1993)
European Journal of Biochemistry
, vol.217
, pp. 457-468
-
-
Portais, J.-C.1
Schuster, R.2
Merle, M.3
Canioni, P.4
-
13
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
2148292 18032601
-
DeBerardinis RJ Mancuso A Daikhin E Nissim I Yudkoff M Wehrli S Thompson CB Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis Proc Natl Acad Sci U S A. 2007, 104(49):19345-19350. 2148292 18032601
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, Issue.49
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
Thompson, C.B.7
-
14
-
-
68549092230
-
Intermediary Metabolism
-
New York: Raven Press Ltd R.G. Crystal aJBW
-
Fisher AB Intermediary Metabolism The Lung Scientific Foundations New York: Raven Press Ltd R.G. Crystal aJBW 1991, 5-12.
-
(1991)
The Lung Scientific Foundations
, pp. 5-12
-
-
Fisher, A.B.1
-
16
-
-
0000324202
-
Recent advances in profiling plant metabolites by multinuclear and multidimensional NMR
-
Rockville, Maryland: American Society of Plant Physiologists Shachar-Hill Y, Pfeffer PE
-
Fan TWM Recent advances in profiling plant metabolites by multinuclear and multidimensional NMR Nuclear Magnetic Resonance in plant biology Rockville, Maryland: American Society of Plant Physiologists Shachar-Hill Y, Pfeffer PE 1996, 16:181-254.
-
(1996)
Nuclear Magnetic Resonance in Plant Biology
, vol.16
, pp. 181-254
-
-
Fan, T.W.M.1
-
17
-
-
68549132927
-
Human Lung Cancers Discerned By 13C-Isotopomer Profiling Have Altered Metabolic Pathways
-
Manchester, U.K
-
Fan TW-M Lane AN Farag M Arumugam V Higashi RM Bousamra M Miller DM Human Lung Cancers Discerned By 13C-Isotopomer Profiling Have Altered Metabolic Pathways Third International meeting of the Metabolomics Society; 11-14 June, 2007 Manchester, U.K 2007.
-
(2007)
Third International Meeting of the Metabolomics Society; 11-14 June, 2007
-
-
Fan, T.W.-M.1
Lane, A.N.2
Farag, M.3
Arumugam, V.4
Higashi, R.M.5
Bousamra, M.6
Miller, D.M.7
-
18
-
-
34249870845
-
Quantification and identification of isotopomer distributions of metabolites in crude cell extracts using 1H TOCSY
-
Lane AN Fan TW-M Quantification and identification of isotopomer distributions of metabolites in crude cell extracts using 1H TOCSY Metabolomics 2007, 3:79-86.
-
(2007)
Metabolomics
, vol.3
, pp. 79-86
-
-
Lane, A.N.1
Fan, T.W.-M.2
-
19
-
-
35448932305
-
Isotopomer-based metabolomic analysis by NMR and mass spectrometry
-
17964943
-
Lane AN Fan TW Higashi RM Isotopomer-based metabolomic analysis by NMR and mass spectrometry Methods Cell Biol 2008, 84:541-588. 17964943
-
(2008)
Methods Cell Biol
, vol.84
, pp. 541-588
-
-
Lane, A.N.1
Fan, T.W.2
Higashi, R.M.3
-
20
-
-
38749110011
-
Structure-based profiling of Metabolites and Isotopomers by NMR
-
Fan TW-M Lane AN Structure-based profiling of Metabolites and Isotopomers by NMR Progress in NMR Spectroscopy 2008, 52:69-117.
-
(2008)
Progress in NMR Spectroscopy
, vol.52
, pp. 69-117
-
-
Fan, T.W.-M.1
Lane, A.N.2
-
21
-
-
0001413420
-
Metabolite profiling by one- and two-dimensional NMR analysis of complex mixtures
-
Fan TW-M Metabolite profiling by one- and two-dimensional NMR analysis of complex mixtures Progress in Nuclear Magnetic Resonance Spectroscopy 1996, 28:161-219.
-
(1996)
Progress in Nuclear Magnetic Resonance Spectroscopy
, vol.28
, pp. 161-219
-
-
Fan, T.W.-M.1
-
22
-
-
33745437095
-
Metabolomics-edited transcriptomics analysis of Se anticancer action in human lung cancer cells
-
Fan T Bandura L Higashi R Lane A Metabolomics-edited transcriptomics analysis of Se anticancer action in human lung cancer cells Metabolomics 2005, 1:325-339.
-
(2005)
Metabolomics
, vol.1
, pp. 325-339
-
-
Fan, T.1
Bandura, L.2
Higashi, R.3
Lane, A.4
-
23
-
-
30844471152
-
Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition
-
16308265
-
Azmi J Connelly J Holmes E Nicholson JK Shore RF Griffin JL Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition Biomarkers 2005, 10:401-416. 16308265
-
(2005)
Biomarkers
, vol.10
, pp. 401-416
-
-
Azmi, J.1
Connelly, J.2
Holmes, E.3
Nicholson, J.K.4
Shore, R.F.5
Griffin, J.L.6
-
24
-
-
33646724060
-
Combining desorption electrospray ionization mass spectrometry and nuclear magnetic resonance for differential metabolomics without sample preparation
-
16628593
-
Chen HW Pan ZZ Talaty N Raftery D Cooks RG Combining desorption electrospray ionization mass spectrometry and nuclear magnetic resonance for differential metabolomics without sample preparation Rapid Communications in Mass Spectrometry 2006, 20:1577-1584. 16628593
-
(2006)
Rapid Communications in Mass Spectrometry
, vol.20
, pp. 1577-1584
-
-
Chen, H.W.1
Pan, Z.Z.2
Talaty, N.3
Raftery, D.4
Cooks, R.G.5
-
27
-
-
3542995149
-
In vivo and in vitro metabolomic analysis of anaerobic rice coleoptiles revealed unexpected pathways
-
Fan TWM Lane AN Higashi RM In vivo and in vitro metabolomic analysis of anaerobic rice coleoptiles revealed unexpected pathways Russian Journal of Plant Physiology 2003, 50:787-793.
-
(2003)
Russian Journal of Plant Physiology
, vol.50
, pp. 787-793
-
-
Fan, T.W.M.1
Lane, A.N.2
Higashi, R.M.3
-
28
-
-
0035232521
-
Metabolic engineering for L-lysine production by Corynebacterium glutamicum
-
11816814
-
de Graaf AA Eggeling L Sahm H Metabolic engineering for L-lysine production by Corynebacterium glutamicum Adv Biochem Eng Biotechnol. 2001, 73:9-29. 11816814
-
(2001)
Adv Biochem Eng Biotechnol
, vol.73
, pp. 9-29
-
-
de Graaf, A.A.1
Eggeling, L.2
Sahm, H.3
-
29
-
-
0031804597
-
Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose
-
Lee W-NP Boros LG Puigjaner J Bassilian S Lim S Cascante M Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose Am J Physiol Endocrinol Metab 1998, 274:E843-851.
-
(1998)
Am J Physiol Endocrinol Metab
, vol.274
-
-
Lee, W.-N.P.1
Boros, L.G.2
Puigjaner, J.3
Bassilian, S.4
Lim, S.5
Cascante, M.6
-
30
-
-
0037022527
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)
-
122412 11880625
-
Lu D Mulder H Zhao P Burgess SC Jensen MV Kamzolova S Newgard CB Sherry AD 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS) Proceedings of the National Academy of Sciences of the United States of America 2002, 99:2708-2713. 122412 11880625
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 2708-2713
-
-
Lu, D.1
Mulder, H.2
Zhao, P.3
Burgess, S.C.4
Jensen, M.V.5
Kamzolova, S.6
Newgard, C.B.7
Sherry, A.D.8
-
31
-
-
33845423112
-
Integrating metabolomics and transcriptomics for probing Se anticancer mechanisms
-
17145697
-
Fan TWM Higashi RM Lane AN Integrating metabolomics and transcriptomics for probing Se anticancer mechanisms Drug Metabolism Reviews 2006, 38:707-732. 17145697
-
(2006)
Drug Metabolism Reviews
, vol.38
, pp. 707-732
-
-
Fan, T.W.M.1
Higashi, R.M.2
Lane, A.N.3
-
32
-
-
33846423878
-
Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis
-
16835632
-
Hertz L Peng L Dienel GA Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/ glycogenolysis J Cereb Blood Flow Metab 2007, 27:219-249. 16835632
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 219-249
-
-
Hertz, L.1
Peng, L.2
Dienel, G.A.3
-
34
-
-
7944226627
-
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
-
15533718
-
Altenberg B Greulich KO Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes Genomics 2004, 84:1014-1020. 15533718
-
(2004)
Genomics
, vol.84
, pp. 1014-1020
-
-
Altenberg, B.1
Greulich, K.O.2
-
35
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
11943784
-
Lu HS Forbes RA Verma A Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis Journal of Biological Chemistry 2002, 277:23111-23115. 11943784
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 23111-23115
-
-
Lu, H.S.1
Forbes, R.A.2
Verma, A.3
-
36
-
-
21844479862
-
Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis
-
15905043
-
Erol A Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis Medical Hypotheses 2005, 65:525-529. 15905043
-
(2005)
Medical Hypotheses
, vol.65
, pp. 525-529
-
-
Erol, A.1
-
38
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
16892081
-
King A Selak MA Gottlieb E Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer Oncogene 2006, 25:4675-4682. 16892081
-
(2006)
Oncogene
, vol.25
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
40
-
-
33749495312
-
Estradiol stimulates the biosynthetic pathways of breast cancer cells: Detection by metabolic flux analysis
-
16904360
-
Forbes NS Meadows AL Clark DS Blanch HW Estradiol stimulates the biosynthetic pathways of breast cancer cells: Detection by metabolic flux analysis Metabolic Engineering 2006, 8:639-652. 16904360
-
(2006)
Metabolic Engineering
, vol.8
, pp. 639-652
-
-
Forbes, N.S.1
Meadows, A.L.2
Clark, D.S.3
Blanch, H.W.4
-
41
-
-
0033385223
-
Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction
-
10578094
-
Irani N Wirth M Heuvel van den J Wagner R Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction Biotechnol Bioeng. 1999, 66(4):238-246. 10578094
-
(1999)
Biotechnol Bioeng.
, vol.66
, Issue.4
, pp. 238-246
-
-
Irani, N.1
Wirth, M.2
Heuvel, J.3
Wagner, R.4
-
42
-
-
0034938530
-
Potential mechanisms for the inhibition of tumor cell growth by manganese superoxide dismutase
-
11491650
-
Kim KH Rodriguez AM Carrico PM Melendez JA Potential mechanisms for the inhibition of tumor cell growth by manganese superoxide dismutase Antioxidants & Redox Signaling 2001, 3:361-373. 11491650
-
(2001)
Antioxidants & Redox Signaling
, vol.3
, pp. 361-373
-
-
Kim, K.H.1
Rodriguez, A.M.2
Carrico, P.M.3
Melendez, J.A.4
-
43
-
-
0032532093
-
Analysis of phosphorylated metabolites in crayfish extracts by two-dimensional 1H-31P NMR heteronuclear total correlation spectroscopy (hetero TOCSY)
-
9799525
-
Gradwell MJ Fan TWM Lane AN Analysis of phosphorylated metabolites in crayfish extracts by two-dimensional 1H-31P NMR heteronuclear total correlation spectroscopy (hetero TOCSY) Analytical Biochemistry 1998, 263:139-149. 9799525
-
(1998)
Analytical Biochemistry
, vol.263
, pp. 139-149
-
-
Gradwell, M.J.1
Fan, T.W.M.2
Lane, A.N.3
-
44
-
-
33745728711
-
MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics
-
16808440
-
Broeckling CD Reddy IR Duran AL Zhao X Sumner LW MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics Anal Chem 2006, 78:4334-4341. 16808440
-
(2006)
Anal Chem
, vol.78
, pp. 4334-4341
-
-
Broeckling, C.D.1
Reddy, I.R.2
Duran, A.L.3
Zhao, X.4
Sumner, L.W.5
-
45
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method
-
11846609
-
Livak KJ Schmittgen TD Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method Methods 2001, 25:402-408. 11846609
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|