메뉴 건너뛰기




Volumn 36, Issue 10, 2006, Pages 2755-2767

Peripheral B cell receptor editing may promote the production of high-affinity autoantibodies in CD22-deficient mice

Author keywords

Autoantibodies; Autoimmunity; B cells; Systemic lupus erythematosus; Tolerance

Indexed keywords

AUTOANTIBODY; B LYMPHOCYTE RECEPTOR; CD22 ANTIGEN; DNA ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

EID: 33750266512     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636190     Document Type: Article
Times cited : (11)

References (70)
  • 1
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin, B. L., Systemic lupus erythematosus. Cell 1996. 85: 303-306.
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.L.1
  • 2
    • 0028292951 scopus 로고
    • Genetic and structural evidence for antigen selection of anti-DNA antibodies
    • Radic, M. Z. and Weigert, M., Genetic and structural evidence for antigen selection of anti-DNA antibodies. Annu. Rev. Immunol. 1994. 12: 487-520.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 487-520
    • Radic, M.Z.1    Weigert, M.2
  • 3
    • 0028096717 scopus 로고
    • Structure-function correlates of auto-antibodies to nucleic acids. Lessons from immunochemical, genetic and structural studies
    • Eilat, D. and Anderson, W. F., Structure-function correlates of auto-antibodies to nucleic acids. Lessons from immunochemical, genetic and structural studies. Mol. Immunol. 1994. 31: 1377-1390.
    • (1994) Mol. Immunol. , vol.31 , pp. 1377-1390
    • Eilat, D.1    Anderson, W.F.2
  • 4
    • 0022273898 scopus 로고
    • Murine models of systemic lupus erythematosus
    • Theofilopoulos, A. N. and Dixon, F. J., Murine models of systemic lupus erythematosus. Adv. Immunol. 1985. 37: 269-390.
    • (1985) Adv. Immunol. , vol.37 , pp. 269-390
    • Theofilopoulos, A.N.1    Dixon, F.J.2
  • 5
    • 0001404231 scopus 로고
    • Animal models of systemic lupus erythematosus
    • In Wallace, D. and Hahn, B. (Eds) Lea & Febiger, Philadelphia
    • Hahn, B., Animal models of systemic lupus erythematosus. In Wallace, D. and Hahn, B. (Eds) Dubois' Lupus Erythematosus. Lea & Febiger, Philadelphia 1993, 157-177.
    • (1993) Dubois' Lupus Erythematosus , pp. 157-177
    • Hahn, B.1
  • 6
    • 0034816964 scopus 로고    scopus 로고
    • Delineating the genetic basis of systemic lupus erythematosus
    • Wakeland, E. K., Liu, K., Graham, R. R. and Behrens, T. W., Delineating the genetic basis of systemic lupus erythematosus. Immunity 2001. 15: 397-408.
    • (2001) Immunity , vol.15 , pp. 397-408
    • Wakeland, E.K.1    Liu, K.2    Graham, R.R.3    Behrens, T.W.4
  • 7
    • 0034041159 scopus 로고    scopus 로고
    • Lupus, DNase and defective disposal of cellular debris
    • Walport, M. J., Lupus, DNase and defective disposal of cellular debris. Nat. Genet. 2000. 25: 135-136.
    • (2000) Nat. Genet. , vol.25 , pp. 135-136
    • Walport, M.J.1
  • 8
    • 0030993376 scopus 로고    scopus 로고
    • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    • Tedder, T. F., Tuscano, J., Sato, S. and Kehrl, J. H., CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu. Rev. Immunol. 1997. 15: 481-504.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 481-504
    • Tedder, T.F.1    Tuscano, J.2    Sato, S.3    Kehrl, J.H.4
  • 11
    • 0030950344 scopus 로고    scopus 로고
    • Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment
    • Cyster, J. G. and Goodnow, C. C., Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment. Immunity 1997. 6: 509-517.
    • (1997) Immunity , vol.6 , pp. 509-517
    • Cyster, J.G.1    Goodnow, C.C.2
  • 14
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
    • Sato, S., Miller, A. S., Inaoki, M., Bock, C. B., Jansen, P. J., Tang, M. L. and Tedder, T. F., CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice. Immunity 1996. 5: 551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 15
  • 16
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe, T. L., Williams, G. T., Batista, F. D. and Neuberger, M. S., Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J. Exp. Med. 1999. 189: 1307-1313.
    • (1999) J. Exp. Med. , vol.189 , pp. 1307-1313
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4
  • 17
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythernatosus: An autoimmune disease of B cell hyperactivity
    • Lipsky, P. E., Systemic lupus erythernatosus: An autoimmune disease of B cell hyperactivity. Nat. Immunol. 2001. 2: 764-766.
    • (2001) Nat. Immunol. , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 18
    • 0034665505 scopus 로고    scopus 로고
    • Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22a lupus-prone mice
    • Mary, C., Laporte, C., Parzy, D., Santiago, M. L., Stefani, F., Lajaunias, F., Parkhouse, R. M. et al., Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22a lupus-prone mice. J. Immunol. 2000. 165: 2987-2996.
    • (2000) J. Immunol. , vol.165 , pp. 2987-2996
    • Mary, C.1    Laporte, C.2    Parzy, D.3    Santiago, M.L.4    Stefani, F.5    Lajaunias, F.6    Parkhouse, R.M.7
  • 19
    • 0037342154 scopus 로고    scopus 로고
    • B cell inhibitory receptors and autoimmunity
    • Pritchard, N. R. and Smith, K. G., B cell inhibitory receptors and autoimmunity. Immunology 2003. 108: 263-273.
    • (2003) Immunology , vol.108 , pp. 263-273
    • Pritchard, N.R.1    Smith, K.G.2
  • 20
    • 0032212186 scopus 로고    scopus 로고
    • B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain
    • Pewzner-Jung, Y., Friedmann, D., Sonoda, E., Jung, S., Rajewsky, K. and Eilat, D., B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain. J. Immunol. 1998. 161: 4634-4645.
    • (1998) J. Immunol. , vol.161 , pp. 4634-4645
    • Pewzner-Jung, Y.1    Friedmann, D.2    Sonoda, E.3    Jung, S.4    Rajewsky, K.5    Eilat, D.6
  • 21
    • 0036241159 scopus 로고    scopus 로고
    • The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status
    • Yachimovich, N., Mostoslavsky, G., Yarkoni, Y., Verbovetski, I. and Eilat, D., The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status. Eur. J. Immunol. 2002. 32: 1164-1174.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1164-1174
    • Yachimovich, N.1    Mostoslavsky, G.2    Yarkoni, Y.3    Verbovetski, I.4    Eilat, D.5
  • 23
    • 0029936944 scopus 로고    scopus 로고
    • Clonal anergy of B cells: A flexible, reversible, and quantitative concept
    • Nossal, G. J., Clonal anergy of B cells: A flexible, reversible, and quantitative concept. J. Exp. Med. 1996-183: 1953-1956.
    • (1996) J. Exp. Med. , vol.183 , pp. 1953-1956
    • Nossal, G.J.1
  • 24
    • 0034608364 scopus 로고    scopus 로고
    • Revising B cell receptors
    • Nemazee, D. and Weigert, M., Revising B cell receptors. J. Exp. Med. 2000. 191: 1813-1817.
    • (2000) J. Exp. Med. , vol.191 , pp. 1813-1817
    • Nemazee, D.1    Weigert, M.2
  • 25
    • 0029807629 scopus 로고    scopus 로고
    • B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen
    • Lang, J., Jackson, M., Teyton, L., Brunmark, A., Kane, K. and Nemazee, D., B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. J. Exp. Med. 1996. 184: 1685-1697.
    • (1996) J. Exp. Med. , vol.184 , pp. 1685-1697
    • Lang, J.1    Jackson, M.2    Teyton, L.3    Brunmark, A.4    Kane, K.5    Nemazee, D.6
  • 26
    • 2942652985 scopus 로고    scopus 로고
    • Receptor editing is the main mechanism of B cell tolerance toward membrane antigens
    • Halverson, R., Torres, R. M. and Pelanda, R., Receptor editing is the main mechanism of B cell tolerance toward membrane antigens. Nat. Immunol. 2004. 5: 645-650.
    • (2004) Nat. Immunol. , vol.5 , pp. 645-650
    • Halverson, R.1    Torres, R.M.2    Pelanda, R.3
  • 27
    • 0033561554 scopus 로고    scopus 로고
    • Production of high affinity autoantibodies in autoimmune New Zealand black/New Zealand white F1 mice targeted with an anti-DNA heavy chain
    • Friedmann, D., Yachimovich, N., Mostoslavsky, G., Pewzner-Jung, Y., Ben-Yehuda, A., Rajewsky, K. and Eilat, D., Production of high affinity autoantibodies in autoimmune New Zealand black/New Zealand white F1 mice targeted with an anti-DNA heavy chain. J. Immunol. 1999. 162: 4406-4416.
    • (1999) J. Immunol. , vol.162 , pp. 4406-4416
    • Friedmann, D.1    Yachimovich, N.2    Mostoslavsky, G.3    Pewzner-Jung, Y.4    Ben-Yehuda, A.5    Rajewsky, K.6    Eilat, D.7
  • 28
    • 0141539327 scopus 로고    scopus 로고
    • Autoimmune NZB/NZW F1 mice utilize B cell receptor editing for generating high-affinity anti-dsDNA autoantibodies from low-affinity precursors
    • Yachimovich-Cohen, N., Fischel, R., Bachar, N., Yarkoni, Y. and Eilat, D., Autoimmune NZB/NZW F1 mice utilize B cell receptor editing for generating high-affinity anti-dsDNA autoantibodies from low-affinity precursors. Eur. J. Immunol. 2003. 33: 2469-2478.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2469-2478
    • Yachimovich-Cohen, N.1    Fischel, R.2    Bachar, N.3    Yarkoni, Y.4    Eilat, D.5
  • 29
    • 0030584886 scopus 로고    scopus 로고
    • Structural elements controlling anti-DNA antibody affinity and their relationship to anti-phosphorylcholine activity
    • Pewzner-Jung, Y., Simon, T. and Eilat, D., Structural elements controlling anti-DNA antibody affinity and their relationship to anti-phosphorylcholine activity. J. Immunol. 1996. 156: 3065-3073.
    • (1996) J. Immunol. , vol.156 , pp. 3065-3073
    • Pewzner-Jung, Y.1    Simon, T.2    Eilat, D.3
  • 30
    • 0023718496 scopus 로고
    • V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice
    • Eilat, D., Webster, D. M. and Rees, A. R., V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice. J. Immunol. 1988. 141: 1745-1753.
    • (1988) J. Immunol. , vol.141 , pp. 1745-1753
    • Eilat, D.1    Webster, D.M.2    Rees, A.R.3
  • 31
    • 1342300520 scopus 로고    scopus 로고
    • Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice
    • Liang, Z., Xie, C., Chen, C., Kreska, D., Hsu, K., Li, L., Zhou, X. J. and Mohan, C., Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice. J. Exp. Med. 2004. 199: 381-398.
    • (2004) J. Exp. Med. , vol.199 , pp. 381-398
    • Liang, Z.1    Xie, C.2    Chen, C.3    Kreska, D.4    Hsu, K.5    Li, L.6    Zhou, X.J.7    Mohan, C.8
  • 34
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., Constantinescu, A., Morrow, T., Baxter, M. and Peng, A., Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 1993. 7: 2520-2532.
    • (1993) Genes Dev. , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 35
    • 0032822989 scopus 로고    scopus 로고
    • Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice
    • Brard, F., Shannon, M., Prak, E. L., Litwin, S. and Weigert, M., Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice. J. Exp. Med. 1999. 190: 691-704.
    • (1999) J. Exp. Med. , vol.190 , pp. 691-704
    • Brard, F.1    Shannon, M.2    Prak, E.L.3    Litwin, S.4    Weigert, M.5
  • 37
  • 38
    • 1642540587 scopus 로고    scopus 로고
    • Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis
    • Waters, S. T., McDuffie, M., Bagavant, H., Deshmukh, U. S., Gaskin, F., Jiang, C., Tung, K. S. and Fu, S. M., Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis. J. Exp. Med. 2004. 199. 255-264.
    • (2004) J. Exp. Med. , vol.199 , pp. 255-264
    • Waters, S.T.1    McDuffie, M.2    Bagavant, H.3    Deshmukh, U.S.4    Gaskin, F.5    Jiang, C.6    Tung, K.S.7    Fu, S.M.8
  • 40
    • 5444234832 scopus 로고    scopus 로고
    • CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms
    • Poe, J. C., Fujimoto, Y., Hasegawa, M., Haas, K. M., Miller, A. G., Sanford, I. G., Bock, C. B. et al., CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms. Nat. Immunol 2004. 5: 1078-1087.
    • (2004) Nat. Immunol , vol.5 , pp. 1078-1087
    • Poe, J.C.1    Fujimoto, Y.2    Hasegawa, M.3    Haas, K.M.4    Miller, A.G.5    Sanford, I.G.6    Bock, C.B.7
  • 41
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
    • Sato, S., Miller, A. S., Inaoki, M., Bock, C. B., Jansen, P. J., Tang, M. L. K. and Tedder, T. F., CD22 is both positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice. Immunity 1996. 5: 551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.K.6    Tedder, T.F.7
  • 42
    • 0020082244 scopus 로고
    • A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE
    • Gleichmann, E., Van Elven, E. H. and Van der Veen, J. P., A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE. Eur. J. Immunol. 1982. 12: 152-159.
    • (1982) Eur. J. Immunol. , vol.12 , pp. 152-159
    • Gleichmann, E.1    Van Elven, E.H.2    Van der Veen, J.P.3
  • 46
    • 0029854905 scopus 로고    scopus 로고
    • A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: Implications for the origins of autoantibodies in autoimmune disease
    • Hannum, L. G., Ni, D., Haberman, A. M., Weigert, M. G. and Shlomchik, M. J., A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: Implications for the origins of autoantibodies in autoimmune disease. J. Exp. Med. 1996. 184: 1269-1278.
    • (1996) J. Exp. Med. , vol.184 , pp. 1269-1278
    • Hannum, L.G.1    Ni, D.2    Haberman, A.M.3    Weigert, M.G.4    Shlomchik, M.J.5
  • 49
    • 0030475466 scopus 로고    scopus 로고
    • Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells
    • Hikida, M., Mori, M., Takai, T., Tomochika, K., Hamatani, K. and Ohmori, H., Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells. Science 1996. 274: 2092-2094.
    • (1996) Science , vol.274 , pp. 2092-2094
    • Hikida, M.1    Mori, M.2    Takai, T.3    Tomochika, K.4    Hamatani, K.5    Ohmori, H.6
  • 50
    • 0030460833 scopus 로고    scopus 로고
    • Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells
    • Han, S., Zheng, B., Schatz, D. G., Spanopoulou, E. and Kelsoe, G., Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science 1996. 274: 2094-2097.
    • (1996) Science , vol.274 , pp. 2094-2097
    • Han, S.1    Zheng, B.2    Schatz, D.G.3    Spanopoulou, E.4    Kelsoe, G.5
  • 51
    • 0030803748 scopus 로고    scopus 로고
    • V(D)J recombination in mature B cells: A mechanism for altering antibody responses
    • Papavasiliou, F., Casellas, R., Sub, H., Qin, X. F., Besmer, E., Pelanda, R., Nemazee, D. et al., V(D)J recombination in mature B cells: A mechanism for altering antibody responses. Science 1997. 278: 298-301.
    • (1997) Science , vol.278 , pp. 298-301
    • Papavasiliou, F.1    Casellas, R.2    Sub, H.3    Qin, X.F.4    Besmer, E.5    Pelanda, R.6    Nemazee, D.7
  • 52
    • 0033180183 scopus 로고    scopus 로고
    • RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues
    • Monroe, R. J., Seidl, K. J., Gaertner, F., Han, S., Chen, F., Sekiguchi, J., Wang, J. et al., RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. Immunity 1999. 11: 201-212.
    • (1999) Immunity , vol.11 , pp. 201-212
    • Monroe, R.J.1    Seidl, K.J.2    Gaertner, F.3    Han, S.4    Chen, F.5    Sekiguchi, J.6    Wang, J.7
  • 53
    • 0033549813 scopus 로고    scopus 로고
    • Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization
    • Yu, W., Nagaoka, H., Jankovic, M., Misulovin, Z., Suh, H., Rolink, A., Melchers, F. et al., Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization. Nature 1999. 400: 682-687.
    • (1999) Nature , vol.400 , pp. 682-687
    • Yu, W.1    Nagaoka, H.2    Jankovic, M.3    Misulovin, Z.4    Suh, H.5    Rolink, A.6    Melchers, F.7
  • 54
    • 10344265955 scopus 로고    scopus 로고
    • Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing
    • Wakui, M., Kim, J., Butfiloski, E. J., Morel, L. and Sobel, E. S., Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing. J. Immunol. 2004. 173: 7368-7376.
    • (2004) J. Immunol. , vol.173 , pp. 7368-7376
    • Wakui, M.1    Kim, J.2    Butfiloski, E.J.3    Morel, L.4    Sobel, E.S.5
  • 56
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow, C. C., Crosbie, J., Adelstein, S., Lavoie, T. B., Smith-Gill, S. J., Brink, R. A., Pritchard-Briscoe, H. et al., Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 1988. 334: 676-682.
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1    Crosbie, J.2    Adelstein, S.3    Lavoie, T.B.4    Smith-Gill, S.J.5    Brink, R.A.6    Pritchard-Briscoe, H.7
  • 57
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S. B., Crosbie, J., Brink, R., Kantor, A. B., Basten, A. and Goodnow, C. C., Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 1991. 353: 765-769.
    • (1991) Nature , vol.353 , pp. 765-769
    • Hartley, S.B.1    Crosbie, J.2    Brink, R.3    Kantor, A.B.4    Basten, A.5    Goodnow, C.C.6
  • 59
    • 0029059370 scopus 로고
    • Soluble antigen can cause enhanced apoptosis of germinal-centre B cells
    • Pulendran, B., Kannourakis, G., Nouri, S., Smith, K. G. and Nossal, G. J., Soluble antigen can cause enhanced apoptosis of germinal-centre B cells. Nature 1995. 375: 331-334.
    • (1995) Nature , vol.375 , pp. 331-334
    • Pulendran, B.1    Kannourakis, G.2    Nouri, S.3    Smith, K.G.4    Nossal, G.J.5
  • 60
    • 0029014435 scopus 로고
    • Antigen-induced B-cell death and elimination during germinal-centre immune responses
    • Shokat, K. M. and Goodnow, C. C., Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature 1995. 375: 334-338.
    • (1995) Nature , vol.375 , pp. 334-338
    • Shokat, K.M.1    Goodnow, C.C.2
  • 61
    • 0036163380 scopus 로고    scopus 로고
    • CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals
    • Chung, J. B., Sater, R. A., Fields, M. L., Erikson, J. and Monroe, J. G., CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals. Int. Immunol. 2002. 14: 157-166.
    • (2002) Int. Immunol. , vol.14 , pp. 157-166
    • Chung, J.B.1    Sater, R.A.2    Fields, M.L.3    Erikson, J.4    Monroe, J.G.5
  • 62
    • 2242446203 scopus 로고    scopus 로고
    • Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling
    • Petro, J. B., Gerstein, R. M., Lowe, J., Carter, R. S., Shinners, N. and Khan, W. N., Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling. J. Biol. Chem. 2002. 277: 48009-48019.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48009-48019
    • Petro, J.B.1    Gerstein, R.M.2    Lowe, J.3    Carter, R.S.4    Shinners, N.5    Khan, W.N.6
  • 63
    • 0031879766 scopus 로고    scopus 로고
    • Rescue of self-reactive B cells by provision of T cell help in vivo
    • Cook, M. C., Basten, A. and Fazekas de St Groth, B., Rescue of self-reactive B cells by provision of T cell help in vivo. Eur. J. Immunol. 1998. 28: 2549-2558.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2549-2558
    • Cook, M.C.1    Basten, A.2    Fazekas de St Groth, B.3
  • 64
    • 33646029133 scopus 로고    scopus 로고
    • Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mcie
    • Chen, C., Li, H., Tian, Q., Beardall, M., Xu, Y., Casanova, N. and Weigert, M., Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mcie. J. Immunol. 2006. 176: 5183-5190.
    • (2006) J. Immunol. , vol.176 , pp. 5183-5190
    • Chen, C.1    Li, H.2    Tian, Q.3    Beardall, M.4    Xu, Y.5    Casanova, N.6    Weigert, M.7
  • 65
    • 23244447690 scopus 로고    scopus 로고
    • In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance
    • Hippen, K. L., Schram, B. R., Tze, L. E., Pape, K. A., Jenkins, M. K. and Behrens, T. W., In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. J. Immunol. 2005. 175: 909-916.
    • (2005) J. Immunol. , vol.175 , pp. 909-916
    • Hippen, K.L.1    Schram, B.R.2    Tze, L.E.3    Pape, K.A.4    Jenkins, M.K.5    Behrens, T.W.6
  • 66
    • 0034671941 scopus 로고    scopus 로고
    • Ig light chain receptor editing in anergic B cells
    • Tze, L. E., Baness, E. A., Hippen, K. L. and Behrens, T. W., Ig light chain receptor editing in anergic B cells. J. Immunol. 2000. 165: 6796-6802.
    • (2000) J. Immunol. , vol.165 , pp. 6796-6802
    • Tze, L.E.1    Baness, E.A.2    Hippen, K.L.3    Behrens, T.W.4
  • 67
    • 7044286393 scopus 로고    scopus 로고
    • The scope of receptor editing and its association with autoimmunity
    • Verkoczy, L. K, Martensson, A. S. and Nemazee, D., The scope of receptor editing and its association with autoimmunity. Curr. Opin. Immunol. 2004. 16: 808-814.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 808-814
    • Verkoczy, L.K.1    Martensson, A.S.2    Nemazee, D.3
  • 68
    • 0031738699 scopus 로고    scopus 로고
    • Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
    • Rolink, A. G., Andersson, J. and Melchers, F., Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 1998. 28: 3738-3748.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3738-3748
    • Rolink, A.G.1    Andersson, J.2    Melchers, F.3
  • 69
    • 0024472122 scopus 로고
    • Mouse Vk gene classification by nucleic acid sequence similarity
    • Strohal, R., Helmberg, A., Kroemer, G. and Kofler, R., Mouse Vk gene classification by nucleic acid sequence similarity. Immunogenetics 1989. 30: 475-493.
    • (1989) Immunogenetics , vol.30 , pp. 475-493
    • Strohal, R.1    Helmberg, A.2    Kroemer, G.3    Kofler, R.4
  • 70
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedure
    • Holm, S., A simple sequentially rejective multiple test procedure. Scand. J. Statist. 1979. 6: 65-70.
    • (1979) Scand. J. Statist. , vol.6 , pp. 65-70
    • Holm, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.