Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4) P2 in regulating insulin sensitivity defined by knock-in analysis

Biochemical Journal

Volumn 434, Issue 2, 2011, Pages 265-274

  Wullschleger, Stephan ^a   Wasserman, David H ^b   Gray, Alex ^a   Sakamoto, Kei ^a   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Insulin signalling; Phosphoinositide 3 kinase (PI3K); Pleckstrin homology domain (PH domain); Protein tyrosine phosphatase; Tandem pleckstrin homology domain containing protein (TAPP)

Indexed keywords

ADAPTOR PROTEIN; GLUCOSE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN KINASE B; TANDEM PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN 1; TANDEM PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; GLUCOSE TRANSPORT; INSULIN SENSITIVITY; MOUSE; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; WILD TYPE;

ANIMALS; BINDING SITES; EMBRYO, MAMMALIAN; FEMALE; GENE KNOCK-IN TECHNIQUES; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

MUS;

EID: 79951539991     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20102012     Document Type: Article

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