-
1
-
-
33644681926
-
Hydrogen peroxide as a paracrine vascular mediator: Regulation and signaling leading to dysfunction
-
Ardanaz N, Pagano PJ (2006) Hydrogen peroxide as a paracrine vascular mediator: Regulation and signaling leading to dysfunction. Exp Biol Med (Maywood) 231:237–251
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, pp. 237-251
-
-
Ardanaz, N.1
Pagano, P.J.2
-
2
-
-
0035104547
-
Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat
-
Armour J, Tyml K, Lidington D, Wilson JX (2001) Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat. J Appl Physiol 90:795–803
-
(2001)
J Appl Physiol
, vol.90
, pp. 795-803
-
-
Armour, J.1
Tyml, K.2
Lidington, D.3
Wilson, J.X.4
-
3
-
-
31644437329
-
Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia-reperfusion
-
Bailey DM, Raman S, McEneny J, Young IS, Parham KL, Hullin DA, Davies B, McKeeman G, McCord JM, Lewis MH (2006) Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia-reperfusion. Free Radic Biol Med 40:591–600
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 591-600
-
-
Bailey, D.M.1
Raman, S.2
McEneny, J.3
Young, I.S.4
Parham, K.L.5
Hullin, D.A.6
Davies, B.7
McKeeman, G.8
McCord, J.M.9
Lewis, M.H.10
-
4
-
-
0036022393
-
Lack of effectiveness of short-term intravenous micronutrient nutrition in restoring plasma antioxidant status after surgery
-
Baines M, Shenkin A (2002) Lack of effectiveness of short-term intravenous micronutrient nutrition in restoring plasma antioxidant status after surgery. Clin Nutr 21:145–150
-
(2002)
Clin Nutr
, vol.21
, pp. 145-150
-
-
Baines, M.1
Shenkin, A.2
-
5
-
-
0034979392
-
Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis
-
Bateman RM, Jagger JE, Sharpe MD, Ellsworth ML, Mehta S, Ellis CG (2001) Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis. Am J Physiol Heart Circ Physiol 280:H2848–H2856
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
, pp. H2848-H2856
-
-
Bateman, R.M.1
Jagger, J.E.2
Sharpe, M.D.3
Ellsworth, M.L.4
Mehta, S.5
Ellis, C.G.6
-
6
-
-
0029997657
-
Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk
-
Borrelli E, Roux-Lombard P, Grau GE, Girardin E, Ricou B, Dayer J, Suter PM (1996) Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med 24:392–397
-
(1996)
Crit Care Med
, vol.24
, pp. 392-397
-
-
Borrelli, E.1
Roux-Lombard, P.2
Grau, G.E.3
Girardin, E.4
Ricou, B.5
Dayer, J.6
Suter, P.M.7
-
7
-
-
24344499139
-
Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
-
Cai H (2005) Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences. Cardiovasc Res 68:26–36
-
(2005)
Cardiovasc Res
, vol.68
, pp. 26-36
-
-
Cai, H.1
-
8
-
-
0036253437
-
Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: The role of vitamin C
-
Carr AC, Frei B (2002) Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C. J Biol Chem 383:627–636
-
(2002)
J Biol Chem
, vol.383
, pp. 627-636
-
-
Carr, A.C.1
Frei, B.2
-
9
-
-
0036084592
-
Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
-
Cerwinka WH, Cooper D, Krieglstein CF, Feelisch M, Granger DN (2002) Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol 282:H1111–H1117
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
, pp. H1111-H1117
-
-
Cerwinka, W.H.1
Cooper, D.2
Krieglstein, C.F.3
Feelisch, M.4
Granger, D.N.5
-
10
-
-
0037305085
-
Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
-
Cerwinka WH, Cooper D, Krieglstein CF, Ross CR, McCord JM, Granger DN (2003) Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol 284:H535–H541
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
, pp. H535-H541
-
-
Cerwinka, W.H.1
Cooper, D.2
Krieglstein, C.F.3
Ross, C.R.4
McCord, J.M.5
Granger, D.N.6
-
11
-
-
26444521256
-
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
-
Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M (2005) Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc Natl Acad Sci USA 102:13604–13609
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13604-13609
-
-
Chen, Q.1
Espey, M.G.2
Krishna, M.C.3
Mitchell, J.B.4
Corpe, C.P.5
Buettner, G.R.6
Shacter, E.7
Levine, M.8
-
12
-
-
0035140667
-
Tirilazad mesylate improve water immersion stress induced decrease in erythrocyte deformability in the rats
-
Chmiel B, Grabowska-Bochenek R, Piskorska D (2001) Tirilazad mesylate improve water immersion stress induced decrease in erythrocyte deformability in the rats. Med Sci Monit 7:38–41
-
(2001)
Med Sci Monit
, vol.7
, pp. 38-41
-
-
Chmiel, B.1
Grabowska-Bochenek, R.2
Piskorska, D.3
-
13
-
-
4143142181
-
The beneficial effects of antioxidant supplementation in enteral feeding in critically ill patients: A prospective, randomized, double-blind, placebo-controlled trial
-
Crimi E, Liguori A, Condorelli M, Cioffi M, Astuto M, Bontempo P, Pignalosa O, Vietri MT, Molinari AM, Sica V, Della Corte F, Napoli C (2004) The beneficial effects of antioxidant supplementation in enteral feeding in critically ill patients: a prospective, randomized, double-blind, placebo-controlled trial. Anesth Analg 99:857–863
-
(2004)
Anesth Analg
, vol.99
, pp. 857-863
-
-
Crimi, E.1
Liguori, A.2
Condorelli, M.3
Cioffi, M.4
Astuto, M.5
Bontempo, P.6
Pignalosa, O.7
Vietri, M.T.8
Molinari, A.M.9
Sica, V.10
Della Corte, F.11
Napoli, C.12
-
14
-
-
0034898299
-
Ascorbic acid and N-acetylcysteine improve in vitro the function of lymphocytes from mice with endotoxin-induced oxidative stress
-
De la Fuente M, Victor VM (2001) Ascorbic acid and N-acetylcysteine improve in vitro the function of lymphocytes from mice with endotoxin-induced oxidative stress. Free Radic Res 35:73–84
-
(2001)
Free Radic Res
, vol.35
, pp. 73-84
-
-
De La Fuente, M.1
Victor, V.M.2
-
15
-
-
13244281950
-
Protective role of dehydroascorbate in rat liver ischemia-reperfusion injury
-
De Tata V, Brizzi S, Saviozzi M, Lazzarotti A, Fierabracci V, Malvaldi G, Casini A (2005) Protective role of dehydroascorbate in rat liver ischemia-reperfusion injury. J Surg Res 123:215–221
-
(2005)
J Surg Res
, vol.123
, pp. 215-221
-
-
De Tata, V.1
Brizzi, S.2
Saviozzi, M.3
Lazzarotti, A.4
Fierabracci, V.5
Malvaldi, G.6
Casini, A.7
-
16
-
-
20844449351
-
Assessment of ascorbic acid stability in different multilayered parenteral nutrition bags: Critical influence of the bag wall material
-
Dupertuis YM, Ramseyer S, Fathi M, Pichard C (2005) Assessment of ascorbic acid stability in different multilayered parenteral nutrition bags: critical influence of the bag wall material. JPEN J Parenter Enteral Nutr 29:125–130
-
(2005)
JPEN J Parenter Enteral Nutr
, vol.29
, pp. 125-130
-
-
Dupertuis, Y.M.1
Ramseyer, S.2
Fathi, M.3
Pichard, C.4
-
17
-
-
0028228067
-
Ascorbic acid reduces the endotoxin-induced lung injury in awake sheep
-
Dwenger A, Pape HC, Bantel C, Schweitzer G, Krumm K, Grotz M, Lueken B, Funck M, Regel G (1994) Ascorbic acid reduces the endotoxin-induced lung injury in awake sheep. Eur J Clin Invest 24:229–235
-
(1994)
Eur J Clin Invest
, vol.24
, pp. 229-235
-
-
Dwenger, A.1
Pape, H.C.2
Bantel, C.3
Schweitzer, G.4
Krumm, K.5
Grotz, M.6
Lueken, B.7
Funck, M.8
Regel, G.9
-
18
-
-
0034332693
-
Neutrophil superoxide anion–generating capacity, endothelial function and oxidative stress in chronic heart failure: Effects of short- and long-term vitamin C therapy
-
Ellis GR, Anderson RA, Lang D, Blackman DJ, Morris RH, Morris-Thurgood J, McDowell IF, Jackson SK, Lewis MJ, Frenneaux MP (2000) Neutrophil superoxide anion–generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy. J Am Coll Cardiol 36:1474–1482
-
(2000)
J am Coll Cardiol
, vol.36
, pp. 1474-1482
-
-
Ellis, G.R.1
Erson, R.A.2
Lang, D.3
Blackman, D.J.4
Morris, R.H.5
Morris-Thurgood, J.6
McDowell, I.F.7
Jackson, S.K.8
Lewis, M.J.9
Frenneaux, M.P.10
-
19
-
-
1942438660
-
Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing
-
Eskurza I, Monahan KD, Robinson JA, Seals DR (2004) Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol 556:315–324
-
(2004)
J Physiol
, vol.556
, pp. 315-324
-
-
Eskurza, I.1
Monahan, K.D.2
Robinson, J.A.3
Seals, D.R.4
-
20
-
-
0036479117
-
Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells
-
Fan J, Frey RS, Rahman A, Malik AB (2002) Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells. J Biol Chem 277:3404–3411
-
(2002)
J Biol Chem
, vol.277
, pp. 3404-3411
-
-
Fan, J.1
Frey, R.S.2
Rahman, A.3
Malik, A.B.4
-
21
-
-
24944489381
-
Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites
-
Ferlitsch A, Pleiner J, Mittermayer F, Schaller G, Homoncik M, Peck-Radosavljevic M, Wolzt M (2005) Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites. Crit Care Med 33:2028–2033
-
(2005)
Crit Care Med
, vol.33
, pp. 2028-2033
-
-
Ferlitsch, A.1
Pleiner, J.2
Mittermayer, F.3
Schaller, G.4
Homoncik, M.5
Peck-Radosavljevic, M.6
Wolzt, M.7
-
22
-
-
33645780634
-
Endothelial nitric oxide synthase in vascular disease: From marvel to menace
-
Forstermann U, Munzel T (2006) Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 113:1708–1714
-
(2006)
Circulation
, vol.113
, pp. 1708-1714
-
-
Forstermann, U.1
Munzel, T.2
-
23
-
-
0029860081
-
Xanthine oxidase activity and free radical generation in patients with sepsis syndrome
-
Galley HF, Davies MJ, Webster NR (1996) Xanthine oxidase activity and free radical generation in patients with sepsis syndrome. Crit Care Med 24:1649–1653
-
(1996)
Crit Care Med
, vol.24
, pp. 1649-1653
-
-
Galley, H.F.1
Davies, M.J.2
Webster, N.R.3
-
24
-
-
33646022817
-
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation
-
Gaut JP, Belaaouaj A, Byun J, Roberts LJ 2nd, Maeda N, Frei B, Heinecke JW (2006) Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. Free Radic Biol Med 40:1494–1501
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1494-1501
-
-
Gaut, J.P.1
Belaaouaj, A.2
Byun, J.3
Roberts, L.J.4
Maeda, N.5
Frei, B.6
Heinecke, J.W.7
-
25
-
-
9344267214
-
Effect of sepsis on skeletal muscle oxygen consumption and tissue oxygenation: Interpreting capillary oxygen transport data using a mathematical model
-
Goldman D, Bateman RM, Ellis CG (2004) Effect of sepsis on skeletal muscle oxygen consumption and tissue oxygenation: interpreting capillary oxygen transport data using a mathematical model. Am J Physiol Heart Circ Physiol 287:H2535–H2544
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, pp. H2535-H2544
-
-
Goldman, D.1
Bateman, R.M.2
Ellis, C.G.3
-
26
-
-
11144356447
-
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species
-
Goyal P, Weissmann N, Grimminger F, Hegel C, Bader L, Rose F, Fink L, Ghofrani HA, Schermuly RT, Schmidt HH, Seeger W, Hanze J (2004) Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species. Free Radic Biol Med 36:1279–1288
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 1279-1288
-
-
Goyal, P.1
Weissmann, N.2
Grimminger, F.3
Hegel, C.4
Bader, L.5
Rose, F.6
Fink, L.7
Ghofrani, H.A.8
Schermuly, R.T.9
Schmidt, H.H.10
Seeger, W.11
Hanze, J.12
-
27
-
-
0033781454
-
Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
-
Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M (2000) Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 20:2175–2183
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2175-2183
-
-
Griendling, K.K.1
Sorescu, D.2
Lassegue, B.3
Ushio-Fukai, M.4
-
28
-
-
5344279750
-
Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts
-
Guaiquil VH, Golde DW, Beckles DL, Mascareno EJ, Siddiqui MA (2004) Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts. Free Radic Biol Med 37:1419–1429
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1419-1429
-
-
Guaiquil, V.H.1
Golde, D.W.2
Beckles, D.L.3
Mascareno, E.J.4
Siddiqui, M.A.5
-
29
-
-
17844398242
-
Vitamins E and C are safe across a broad range of intakes
-
Hathcock JN, Azzi A, Blumberg J, Bray T, Dickinson A, Frei B, Jialal I, Johnston CS, Kelly FJ, Kraemer K, Packer L, Parthasarathy S, Sies H, Traber MG (2005) Vitamins E and C are safe across a broad range of intakes. Am J Clin Nutr 81:736–745
-
(2005)
Am J Clin Nutr
, vol.81
, pp. 736-745
-
-
Hathcock, J.N.1
Azzi, A.2
Blumberg, J.3
Bray, T.4
Dickinson, A.5
Frei, B.6
Jialal, I.7
Johnston, C.S.8
Kelly, F.J.9
Kraemer, K.10
Packer, L.11
Parthasarathy, S.12
Sies, H.13
Traber, M.G.14
-
30
-
-
0035949516
-
Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
-
Huang J, Agus DB, Winfree CJ, Kiss S, Mack WJ, McTaggart RA, Choudhri TF, Kim LJ, Mocco J, Pinsky DJ, Fox WD, Israel RJ, Boyd TA, Golde DW, Connolly ES Jr (2001) Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. Proc Natl Acad Sci USA 98:11720–11724
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11720-11724
-
-
Huang, J.1
Agus, D.B.2
Winfree, C.J.3
Kiss, S.4
Mack, W.J.5
McTaggart, R.A.6
Choudhri, T.F.7
Kim, L.J.8
Mocco, J.9
Pinsky, D.J.10
Fox, W.D.11
Israel, R.J.12
Boyd, T.A.13
Golde, D.W.14
Connolly, E.S.15
-
31
-
-
0032476697
-
Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations
-
Jackson TS, Xu A, Vita JA, Keaney JF Jr (1998) Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations. Circ Res 83:916–922
-
(1998)
Circ Res
, vol.83
, pp. 916-922
-
-
Jackson, T.S.1
Xu, A.2
Vita, J.A.3
Keaney, J.F.4
-
32
-
-
26044435676
-
Exogenous superoxide mediates pro-oxidative, proinflammatory, and procoagulatory changes in primary endothelial cell cultures
-
Jacobi J, Kristal B, Chezar J, Shaul SM, Sela S (2005) Exogenous superoxide mediates pro-oxidative, proinflammatory, and procoagulatory changes in primary endothelial cell cultures. Free Radic Biol Med 39:1238–1248
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 1238-1248
-
-
Jacobi, J.1
Kristal, B.2
Chezar, J.3
Shaul, S.M.4
Sela, S.5
-
33
-
-
4143119045
-
Effect of ascorbic acid on hepatic vasoregulatory gene expression during polymicrobial sepsis
-
Kim JY, Lee SM (2004) Effect of ascorbic acid on hepatic vasoregulatory gene expression during polymicrobial sepsis. Life Sci 75:2015–2026
-
(2004)
Life Sci
, vol.75
, pp. 2015-2026
-
-
Kim, J.Y.1
Lee, S.M.2
-
34
-
-
33744823294
-
Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells
-
Kim HJ, Lee SI, Lee DH, Smith D, Jo H, Schellhorn HE, Boo YC (2006) Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells. Biochem Biophys Res Commun 345:1657–1662
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1657-1662
-
-
Kim, H.J.1
Lee, S.I.2
Lee, D.H.3
Smith, D.4
Jo, H.5
Schellhorn, H.E.6
Boo, Y.C.7
-
35
-
-
23044455420
-
Association between hydrogen peroxide-dependent byproducts of ascorbic acid and increased hepatic acetyl-CoA carboxylase activity
-
Knafo L, Chessex P, Rouleau T, Lavoie JC (2005) Association between hydrogen peroxide-dependent byproducts of ascorbic acid and increased hepatic acetyl-CoA carboxylase activity. Clin Chem 51:1462–1471
-
(2005)
Clin Chem
, vol.51
, pp. 1462-1471
-
-
Knafo, L.1
Chessex, P.2
Rouleau, T.3
Lavoie, J.C.4
-
36
-
-
0037446983
-
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells
-
Knowles HJ, Raval RR, Harris AL, Ratcliffe PJ (2003) Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Res 63:1764–1768
-
(2003)
Cancer Res
, vol.63
, pp. 1764-1768
-
-
Knowles, H.J.1
Raval, R.R.2
Harris, A.L.3
Ratcliffe, P.J.4
-
37
-
-
0036071854
-
Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: Intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition
-
Korcok J, Wu F, Tyml K, Hammond RR, Wilson JX (2002) Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: Intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition. J Neurochem 81:185–193
-
(2002)
J Neurochem
, vol.81
, pp. 185-193
-
-
Korcok, J.1
Wu, F.2
Tyml, K.3
Hammond, R.R.4
Wilson, J.X.5
-
38
-
-
0345283081
-
Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes
-
Korcok J, Dixon SJ, Lo TC, Wilson JX (2003) Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes. Brain Res 993:201–207
-
(2003)
Brain Res
, vol.993
, pp. 201-207
-
-
Korcok, J.1
Dixon, S.J.2
Lo, T.C.3
Wilson, J.X.4
-
39
-
-
26444449535
-
Endotoxin increases ascorbate recycling and concentration in mouse liver
-
Kuo SM, Tan CH, Dragan M, Wilson JX (2005) Endotoxin increases ascorbate recycling and concentration in mouse liver. J Nutr 135:2411–2416
-
(2005)
J Nutr
, vol.135
, pp. 2411-2416
-
-
Kuo, S.M.1
Tan, C.H.2
Dragan, M.3
Wilson, J.X.4
-
40
-
-
0036272286
-
Multivitamin solutions for enteral supplementation: A source of peroxides
-
Laborie S, Lavoie JC, Rouleau T, Chessex P (2002) Multivitamin solutions for enteral supplementation: A source of peroxides. Nutrition 18:470–473
-
(2002)
Nutrition
, vol.18
, pp. 470-473
-
-
Laborie, S.1
Lavoie, J.C.2
Rouleau, T.3
Chessex, P.4
-
41
-
-
0036092494
-
Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis
-
Laudes IJ, Chu JC, Sikranth S, Huber-Lang M, Guo RF, Riedemann N, Sarma JV, Schmaier AH, Ward PA (2002) Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. Am J Pathol 160:1867–1875
-
(2002)
Am J Pathol
, vol.160
, pp. 1867-1875
-
-
Laudes, I.J.1
Chu, J.C.2
Sikranth, S.3
Huber-Lang, M.4
Guo, R.F.5
Riedemann, N.6
Sarma, J.V.7
Schmaier, A.H.8
Ward, P.A.9
-
42
-
-
6344285417
-
Endothelial cell superoxide generation: Regulation and relevance for cardiovascular pathophysiology
-
Li JM, Shah AM. (2004) Endothelial cell superoxide generation: Regulation and relevance for cardiovascular pathophysiology. Am J Physiol Regul Integr Comp Physiol 287:R1014–R1030
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.287
, pp. R1014-R1030
-
-
Li, J.M.1
Shah, A.M.2
-
43
-
-
14844349754
-
Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: Role of p47phox phosphorylation and binding to TRAF4
-
Li JM, Fan LM, Christie MR, Shah AM (2005) Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: Role of p47phox phosphorylation and binding to TRAF4. Mol Cell Biol 25:2320–2330
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2320-2330
-
-
Li, J.M.1
Fan, L.M.2
Christie, M.R.3
Shah, A.M.4
-
44
-
-
0037297449
-
Ascorbic acid dynamics in the seriously ill and injured
-
Long CL, Maull KI, Krishnan RS, Laws HL, Geiger JW, Borghesi L, Franks W, Lawson TC, Sauberlich HE (2003) Ascorbic acid dynamics in the seriously ill and injured. J Surg Res 109:144–148
-
(2003)
J Surg Res
, vol.109
, pp. 144-148
-
-
Long, C.L.1
Maull, K.I.2
Krishnan, R.S.3
Laws, H.L.4
Geiger, J.W.5
Borghesi, L.6
Franks, W.7
Lawson, T.C.8
Sauberlich, H.E.9
-
45
-
-
4444273012
-
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: Effect on survival in patients with septic shock
-
Lopez A, Lorente JA, Steingrub J, Bakker J, McLuckie A, Willatts S, Brockway M, Anzueto A, Holzapfel L, Breen D, Silverman MS, Takala J, Donaldson J, Arneson C, Grove G, Grossman S, Grover R (2004) Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med 32:21–30
-
(2004)
Crit Care Med
, vol.32
, pp. 21-30
-
-
Lopez, A.1
Lorente, J.A.2
Steingrub, J.3
Bakker, J.4
McLuckie, A.5
Willatts, S.6
Brockway, M.7
Anzueto, A.8
Holzapfel, L.9
Breen, D.10
Silverman, M.S.11
Takala, J.12
Donaldson, J.13
Arneson, C.14
Grove, G.15
Grossman, S.16
Grover, R.17
-
46
-
-
29644442625
-
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
-
Lu H, Dalgard CL, Mohyeldin A, McFate T, Tait AS, Verma A (2005) Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J Biol Chem 280:41928–41939
-
(2005)
J Biol Chem
, vol.280
, pp. 41928-41939
-
-
Lu, H.1
Dalgard, C.L.2
Mohyeldin, A.3
McFate, T.4
Tait, A.S.5
Verma, A.6
-
47
-
-
33748313144
-
A cerebroprotective dose of intravenous citrate/sorbitol-stabilized dehydroascorbic acid is correlated with increased cerebral ascorbic acid and inhibited lipid peroxidation after murine reperfused stroke
-
Mack WJ, Mocco J, Ducruet AF, Laufer I, King RG, Zhang Y, Guo W, Pinsky DJ, Connolly ES Jr (2006) A cerebroprotective dose of intravenous citrate/sorbitol-stabilized dehydroascorbic acid is correlated with increased cerebral ascorbic acid and inhibited lipid peroxidation after murine reperfused stroke. Neurosurgery 59:383–388
-
(2006)
Neurosurgery
, vol.59
, pp. 383-388
-
-
Mack, W.J.1
Mocco, J.2
Ducruet, A.F.3
Laufer, I.4
King, R.G.5
Zhang, Y.6
Guo, W.7
Pinsky, D.J.8
Connolly, E.S.9
-
48
-
-
0034190373
-
How does ascorbic acid prevent endothelial dysfunction?
-
May JM (2000) How does ascorbic acid prevent endothelial dysfunction? Free Radic Biol Med 28:1421–1429
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1421-1429
-
-
May, J.M.1
-
49
-
-
27544469136
-
Macrophage uptake and recycling of ascorbic acid: Response to activation by lipopolysaccharide
-
May JM, Huang J, Qu ZC (2005) Macrophage uptake and recycling of ascorbic acid: response to activation by lipopolysaccharide. Free Radic Biol Med 39:1449–1459
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 1449-1459
-
-
May, J.M.1
Huang, J.2
Qu, Z.C.3
-
51
-
-
21844463540
-
Statin treatment after onset of sepsis in a murine model improves survival
-
Merx MW, Liehn EA, Graf J, van de Sandt A, Schaltenbrand M, Schrader J, Hanrath P, Weber C (2005) Statin treatment after onset of sepsis in a murine model improves survival. Circulation 112:117–124
-
(2005)
Circulation
, vol.112
, pp. 117-124
-
-
Merx, M.W.1
Liehn, E.A.2
Graf, J.3
Van De Sandt, A.4
Schaltenbrand, M.5
Schrader, J.6
Hanrath, P.7
Weber, C.8
-
52
-
-
0032983447
-
Antioxidant status in patients with acute respiratory distress syndrome
-
Metnitz PG, Bartens C, Fischer M, Fridrich P, Steltzer H, Druml W (1999) Antioxidant status in patients with acute respiratory distress syndrome. Intensive Care Med 25:180–185
-
(1999)
Intensive Care Med
, vol.25
, pp. 180-185
-
-
Metnitz, P.G.1
Bartens, C.2
Fischer, M.3
Fridrich, P.4
Steltzer, H.5
Druml, W.6
-
53
-
-
25444491942
-
Tetrahydrobiopterin corrects Escherichia coli endotoxin-induced endothelial dysfunction
-
Mittermayer F, Pleiner J, Schaller G, Zorn S, Namiranian K, Kapiotis S, Bartel G, Wolfrum M, Brugel M, Thiery J, Macallister RJ, Wolzt M (2005) Tetrahydrobiopterin corrects Escherichia coli endotoxin-induced endothelial dysfunction. Am J Physiol Heart Circ Physiol 289:H1752–H1757
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
, pp. H1752-H1757
-
-
Mittermayer, F.1
Pleiner, J.2
Schaller, G.3
Zorn, S.4
Namiranian, K.5
Kapiotis, S.6
Bartel, G.7
Wolfrum, M.8
Brugel, M.9
Thiery, J.10
Macallister, R.J.11
Wolzt, M.12
-
54
-
-
0142249406
-
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice
-
Miyaji T, Hu X, Yuen PS, Muramatsu Y, Iyer S, Hewitt SM, Star RA (2003) Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Kidney Int 64:1620–1631
-
(2003)
Kidney Int
, vol.64
, pp. 1620-1631
-
-
Miyaji, T.1
Hu, X.2
Yuen, P.S.3
Muramatsu, Y.4
Iyer, S.5
Hewitt, S.M.6
Star, R.A.7
-
55
-
-
4444273747
-
High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers
-
Muhlhofer A, Mrosek S, Schlegel B, Trommer W, Rozario F, Böhles H, Schremmer D, Zoller WG, Biesalski HK (2004) High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers. Eur J Clin Nutr 58:1151–1158
-
(2004)
Eur J Clin Nutr
, vol.58
, pp. 1151-1158
-
-
Muhlhofer, A.1
Mrosek, S.2
Schlegel, B.3
Trommer, W.4
Rozario, F.5
Böhles, H.6
Schremmer, D.7
Zoller, W.G.8
Biesalski, H.K.9
-
56
-
-
0036895263
-
Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients
-
Nathens AB, Neff MJ, Jurkovich GJ, Klotz P, Farver K, Ruzinski JT, Radella F, Garcia I, Maier RV (2002) Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 236:814–822
-
(2002)
Ann Surg
, vol.236
, pp. 814-822
-
-
Nathens, A.B.1
Neff, M.J.2
Jurkovich, G.J.3
Klotz, P.4
Farver, K.5
Ruzinski, J.T.6
Radella, F.7
Garcia, I.8
Maier, R.V.9
-
57
-
-
10944230821
-
Pentastarch in a balanced solution reduces hepatic leukocyte recruitment in early sepsis
-
Ondiveeran HK, Fox-Robichaud AE (2004) Pentastarch in a balanced solution reduces hepatic leukocyte recruitment in early sepsis. Microcirculation 11:679–687
-
(2004)
Microcirculation
, vol.11
, pp. 679-687
-
-
Ondiveeran, H.K.1
Fox-Robichaud, A.E.2
-
58
-
-
0035146571
-
The activity of tissue factor pathway inhibitor in experimental models of superantigen-induced shock and polymicrobial intra-abdominal sepsis
-
Opal SM, Palardy JE, Parejo NA, Creasey AA (2001) The activity of tissue factor pathway inhibitor in experimental models of superantigen-induced shock and polymicrobial intra-abdominal sepsis. Crit Care Med 29:13–17
-
(2001)
Crit Care Med
, vol.29
, pp. 13-17
-
-
Opal, S.M.1
Palardy, J.E.2
Parejo, N.A.3
Creasey, A.A.4
-
59
-
-
1842435160
-
Vitamin C pharmacokinetics: Implications for oral and intravenous use
-
Padayatty SJ, Sun H, Wang Y, Riordan HD, Hewitt SM, Katz A, Wesley RA, Levine M (2004) Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann Intern Med 140:533–537
-
(2004)
Ann Intern Med
, vol.140
, pp. 533-537
-
-
Padayatty, S.J.1
Sun, H.2
Wang, Y.3
Riordan, H.D.4
Hewitt, S.M.5
Katz, A.6
Wesley, R.A.7
Levine, M.8
-
60
-
-
0033013982
-
Effect of isoproterenol on myocardial structure and function in septic rats
-
Piper RD, Li FY, Myers ML, Sibbald WJ (1999) Effect of isoproterenol on myocardial structure and function in septic rats. J Appl Physiol 86:993–1001
-
(1999)
J Appl Physiol
, vol.86
, pp. 993-1001
-
-
Piper, R.D.1
Li, F.Y.2
Myers, M.L.3
Sibbald, W.J.4
-
61
-
-
0242460460
-
Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress
-
Pleiner J, Mittermayer F, Schaller G, Marsik C, MacAllister RJ, Wolzt M (2003) Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress. J Am Coll Cardiol 42:1656–1662
-
(2003)
J am Coll Cardiol
, vol.42
, pp. 1656-1662
-
-
Pleiner, J.1
Mittermayer, F.2
Schaller, G.3
Marsik, C.4
Macallister, R.J.5
Wolzt, M.6
-
62
-
-
14544299688
-
Therapeutic intervention and targets for sepsis
-
Rice TW, Bernard GR (2005) Therapeutic intervention and targets for sepsis. Annu Rev Med 56:225–248
-
(2005)
Annu Rev Med
, vol.56
, pp. 225-248
-
-
Rice, T.W.1
Bernard, G.R.2
-
63
-
-
0035829842
-
Early goal-directed therapy collaborative group. Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M (2001) Early goal-directed therapy collaborative group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
64
-
-
33846918427
-
Microcirculatory dysfunction in the brain precedes changes in evoked potentials in endotoxin-induced sepsis syndrome in rats
-
Rosengarten B, Hecht M, Auch D, Ghofrani HA, Schermuly RT, Grimminger F, Kaps M (2006) Microcirculatory dysfunction in the brain precedes changes in evoked potentials in endotoxin-induced sepsis syndrome in rats. Cerebrovasc Dis 23:140–147
-
(2006)
Cerebrovasc Dis
, vol.23
, pp. 140-147
-
-
Rosengarten, B.1
Hecht, M.2
Auch, D.3
Ghofrani, H.A.4
Schermuly, R.T.5
Grimminger, F.6
Kaps, M.7
-
65
-
-
27144466374
-
Metabolic clearance of the antioxidant ascorbic acid in surgical patients
-
Rumelin A, Humbert T, Luhker O, Drescher A, Fauth U (2005) Metabolic clearance of the antioxidant ascorbic acid in surgical patients. J Surg Res 129:46–51
-
(2005)
J Surg Res
, vol.129
, pp. 46-51
-
-
Rumelin, A.1
Humbert, T.2
Luhker, O.3
Drescher, A.4
Fauth, U.5
-
66
-
-
33750047495
-
Management of sepsis
-
Russell JA (2006) Management of sepsis. N Engl J Med 355:1699–16713
-
(2006)
N Engl J Med
, vol.355
, pp. 1699-16713
-
-
Russell, J.A.1
-
67
-
-
4444233598
-
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
-
Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32:1825–1831
-
(2004)
Crit Care Med
, vol.32
, pp. 1825-1831
-
-
Sakr, Y.1
Dubois, M.J.2
De Backer, D.3
Creteur, J.4
Vincent, J.L.5
-
68
-
-
0036829699
-
Oxidative stress in septic shock and disseminated intravascular coagulation
-
Salvemini D, Cuzzocrea S (2002) Oxidative stress in septic shock and disseminated intravascular coagulation. Free Radic Biol Med 33:1173–1185
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1173-1185
-
-
Salvemini, D.1
Cuzzocrea, S.2
-
69
-
-
23744477944
-
Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension
-
Schneider MP, Delles C, Schmidt BM, Oehmer S, Schwarz TK, Schmieder RE, John S (2005) Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension. Am J Hypertens 18:1111–1117
-
(2005)
Am J Hypertens
, vol.18
, pp. 1111-1117
-
-
Schneider, M.P.1
Delles, C.2
Schmidt, B.M.3
Oehmer, S.4
Schwarz, T.K.5
Schmieder, R.E.6
John, S.7
-
70
-
-
0029917023
-
Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients
-
Schorah CJ, Downing C, Piripitsi A, Gallivan L, Al-Hazaa AH, Sanderson MJ, Bodenham A (1996) Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients. Am J Clin Nutr 63:760–765
-
(1996)
Am J Clin Nutr
, vol.63
, pp. 760-765
-
-
Schorah, C.J.1
Downing, C.2
Piripitsi, A.3
Gallivan, L.4
Al-Hazaa, A.H.5
Sanderson, M.J.6
Bodenham, A.7
-
71
-
-
78650414437
-
Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries
-
Secor D, Li F, Ellis CG, Sharpe MD, Gross PL, Wilson JX, Tyml K (2010) Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries. Intensive Care Med 36:1928–1934
-
(2010)
Intensive Care Med
, vol.36
, pp. 1928-1934
-
-
Secor, D.1
Li, F.2
Ellis, C.G.3
Sharpe, M.D.4
Gross, P.L.5
Wilson, J.X.6
Tyml, K.7
-
72
-
-
5644225578
-
Functional expression of sodium-dependent vitamin C transporter 2 in human endothelial cells
-
Seno T, Inoue N, Matsui K, Ejiri J, Hirata KI, Kawashima S, Yokoyama M (2004) Functional expression of sodium-dependent vitamin C transporter 2 in human endothelial cells. J Vasc Res 41:345–351
-
(2004)
J Vasc Res
, vol.41
, pp. 345-351
-
-
Seno, T.1
Inoue, N.2
Matsui, K.3
Ejiri, J.4
Hirata, K.I.5
Kawashima, S.6
Yokoyama, M.7
-
73
-
-
2642568618
-
Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: Modulatory effect of nitric oxide
-
Sharma P, Raghavan SA, Saini R, Dikshit M (2004) Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide. J Leukoc Biol 75:1070–1078
-
(2004)
J Leukoc Biol
, vol.75
, pp. 1070-1078
-
-
Sharma, P.1
Raghavan, S.A.2
Saini, R.3
Dikshit, M.4
-
75
-
-
11144348137
-
Antioxidant eugenosedin-A protects against lipopolysaccharide-induced hypotension, hyperglycaemia and cytokine immunoreactivity in rats and mice
-
Shen KP, Lo YC, Yang RC, Liu HW, Chen IJ, Wu BN (2005) Antioxidant eugenosedin-A protects against lipopolysaccharide-induced hypotension, hyperglycaemia and cytokine immunoreactivity in rats and mice. J Pharm Pharmacol 57:117–125
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 117-125
-
-
Shen, K.P.1
Lo, Y.C.2
Yang, R.C.3
Liu, H.W.4
Chen, I.J.5
Wu, B.N.6
-
76
-
-
32344436342
-
Platelet recruitment in the murine hepatic microvasculature during experimental sepsis: Role of neutrophils
-
Singer G, Urakami H, Specian RD, Stokes KY, Granger DN (2006) Platelet recruitment in the murine hepatic microvasculature during experimental sepsis: role of neutrophils. Microcirculation 13:89–97
-
(2006)
Microcirculation
, vol.13
, pp. 89-97
-
-
Singer, G.1
Urakami, H.2
Specian, R.D.3
Stokes, K.Y.4
Granger, D.N.5
-
77
-
-
0036634864
-
Vitamin C matters: Increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid
-
Smith AR, Visioli F, Hagen TM (2002) Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid. FASEB J 16:1102–4110
-
(2002)
FASEB J
, vol.16
, pp. 1102-4110
-
-
Smith, A.R.1
Visioli, F.2
Hagen, T.M.3
-
78
-
-
0029792458
-
Endotoxin stimulates hydrogen peroxide detoxifying activity in rat hepatic endothelial cells
-
Spolarics Z, Stein DS, Garcia ZC (1996) Endotoxin stimulates hydrogen peroxide detoxifying activity in rat hepatic endothelial cells. Hepatology 24:691–696
-
(1996)
Hepatology
, vol.24
, pp. 691-696
-
-
Spolarics, Z.1
Stein, D.S.2
Garcia, Z.C.3
-
79
-
-
0037010370
-
Nitroglycerin in septic shock after intravascular volume resuscitation
-
Spronk PE, Ince C, Gardien MJ, Mathura KR, Oudemans-van Straaten HM, Zandstra DF (2002) Nitroglycerin in septic shock after intravascular volume resuscitation. Lancet 360:1395–1396
-
(2002)
Lancet
, vol.360
, pp. 1395-1396
-
-
Spronk, P.E.1
Ince, C.2
Gardien, M.J.3
Mathura, K.R.4
Oudemans-Van Straaten, H.M.5
Zandstra, D.F.6
-
80
-
-
33644851056
-
Tissue factor in cardiovascular diseases: Molecular mechanisms and clinical implications
-
Steffel J, Luscher TF, Tanner FC (2006) Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications. Circulation 113:722–731
-
(2006)
Circulation
, vol.113
, pp. 722-731
-
-
Steffel, J.1
Luscher, T.F.2
Tanner, F.C.3
-
81
-
-
0344436050
-
Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock
-
Stoclet JC, Martinez MC, Ohlmann P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R (1999) Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock. Circulation 100:107–112
-
(1999)
Circulation
, vol.100
, pp. 107-112
-
-
Stoclet, J.C.1
Martinez, M.C.2
Ohlmann, P.3
Chasserot, S.4
Schott, C.5
Kleschyov, A.L.6
Schneider, F.7
Riantsitohaina, R.8
-
82
-
-
0033847308
-
Nitric oxide synthase inhibition increases venular leukocyte rolling and adhesion in septic rats
-
Sundrani R, Easington CR, Mattoo A, Parrillo JE, Hollenberg SM (2000) Nitric oxide synthase inhibition increases venular leukocyte rolling and adhesion in septic rats. Crit Care Med 28:2898–2903
-
(2000)
Crit Care Med
, vol.28
, pp. 2898-2903
-
-
Sundrani, R.1
Easington, C.R.2
Mattoo, A.3
Parrillo, J.E.4
Hollenberg, S.M.5
-
83
-
-
0034019327
-
Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: A randomized, prospective study
-
Tanaka H, Matsuda T, Miyagantani Y, Yukioka T, Matsuda H, Shimazaki S (2000) Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg 135:326–331
-
(2000)
Arch Surg
, vol.135
, pp. 326-331
-
-
Tanaka, H.1
Matsuda, T.2
Miyagantani, Y.3
Yukioka, T.4
Matsuda, H.5
Shimazaki, S.6
-
84
-
-
0034908498
-
Dysfunction of vasomotor reactivity in severe sepsis and septic shock
-
Terborg C, Schummer W, Albrecht M, Reinhart K, Weiller C, Rother J (2001) Dysfunction of vasomotor reactivity in severe sepsis and septic shock. Intensive Care Med 27:1231–1234
-
(2001)
Intensive Care Med
, vol.27
, pp. 1231-1234
-
-
Terborg, C.1
Schummer, W.2
Albrecht, M.3
Reinhart, K.4
Weiller, C.5
Rother, J.6
-
85
-
-
25144481421
-
Effects of vitamin C on intracoronary L-arginine dependent coronary vasodilatation in patients with stable angina
-
Tousoulis D, Xenakis C, Tentolouris C, Davies G, Antoniades C, Crake T, Stefanadis C (2005) Effects of vitamin C on intracoronary L-arginine dependent coronary vasodilatation in patients with stable angina. Heart 91:1319–1323
-
(2005)
Heart
, vol.91
, pp. 1319-1323
-
-
Tousoulis, D.1
Xenakis, C.2
Tentolouris, C.3
Davies, G.4
Antoniades, C.5
Crake, T.6
Stefanadis, C.7
-
86
-
-
23844460546
-
Delayed ascorbate bolus protects against maldistribution of microvascular blood flow in a rat model of sepsis
-
Tyml K, Li F, Wilson JX (2005) Delayed ascorbate bolus protects against maldistribution of microvascular blood flow in a rat model of sepsis. Crit Care Med 33:1823–1828
-
(2005)
Crit Care Med
, vol.33
, pp. 1823-1828
-
-
Tyml, K.1
Li, F.2
Wilson, J.X.3
-
87
-
-
33847051180
-
Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate
-
Vissers MCM, Gunningham SP, Morrison MJ, Dachs GU, Currie MJ (2007) Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate. Free Radic Biol Med, doi: 10.1016/j.freeradbiomed.2006.11.023
-
(2007)
Free Radic Biol Med
-
-
Vissers, M.1
Gunningham, S.P.2
Morrison, M.J.3
Dachs, G.U.4
Currie, M.J.5
-
88
-
-
6344292310
-
Endothelial nitric oxide synthase-deficient mice exhibit increased susceptibility to endotoxin-induced acute renal failure
-
Wang W, Mitra A, Poole B, Falk S, Lucia MS, Tayal S, Schrier R (2004) Endothelial nitric oxide synthase-deficient mice exhibit increased susceptibility to endotoxin-induced acute renal failure. Am J Physiol Renal Physiol 287:F1044–F1048
-
(2004)
Am J Physiol Renal Physiol
, vol.287
, pp. F1044-F1048
-
-
Wang, W.1
Mitra, A.2
Poole, B.3
Falk, S.4
Lucia, M.S.5
Tayal, S.6
Schrier, R.7
-
89
-
-
0036320934
-
Cellular adaptation to hypoxia: O2 sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2 regulated gene expression
-
Wenger RH (2002) Cellular adaptation to hypoxia: O2 sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2 regulated gene expression. FASEB J 16:1151–1162
-
(2002)
FASEB J
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
90
-
-
23944482400
-
Regulation of vitamin C transport
-
Wilson JX (2005) Regulation of vitamin C transport. Annu Rev Nutr 25:105–125
-
(2005)
Annu Rev Nutr
, vol.25
, pp. 105-125
-
-
Wilson, J.X.1
-
91
-
-
25144503255
-
Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes
-
Wilson JX, Dragan M (2005) Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes. Free Radic Biol Med 39:990–998
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 990-998
-
-
Wilson, J.X.1
Dragan, M.2
-
92
-
-
0036135787
-
Free radicals, antioxidants, and neurologic injury: Possible relationship to cerebral protection by anesthetics
-
Wilson JX, Gelb AW (2002) Free radicals, antioxidants, and neurologic injury: Possible relationship to cerebral protection by anesthetics. J Neurosurg Anesthesiol 14:66–79
-
(2002)
J Neurosurg Anesthesiol
, vol.14
, pp. 66-79
-
-
Wilson, J.X.1
Gelb, A.W.2
-
93
-
-
0037834561
-
Progress in clinical neurosciences: Sepsis-associated encephalopathy: Evolving concepts
-
Wilson JX, Young GB (2003) Progress in clinical neurosciences: Sepsis-associated encephalopathy: Evolving concepts. Can J Neurol Sci 30:98–105
-
(2003)
Can J Neurol Sci
, vol.30
, pp. 98-105
-
-
Wilson, J.X.1
Young, G.B.2
-
94
-
-
0030154883
-
Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle
-
Wilson JX, Dixon SJ, Yu J, Nees S, Tyml K (1996) Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle. Microcirculation 3:211–221
-
(1996)
Microcirculation
, vol.3
, pp. 211-221
-
-
Wilson, J.X.1
Dixon, S.J.2
Yu, J.3
Nees, S.4
Tyml, K.5
-
95
-
-
0000171092
-
Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells
-
Wu F, Cepinskas G, Wilson JX, Tyml K (2001) Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells. Microcirculation 8:415–425
-
(2001)
Microcirculation
, vol.8
, pp. 415-425
-
-
Wu, F.1
Cepinskas, G.2
Wilson, J.X.3
Tyml, K.4
-
96
-
-
0037024337
-
Ascorbate inhibits iNOS expression in endotoxin- and IFN gamma-stimulated rat skeletal muscle endothelial cells
-
Wu F, Tyml K, Wilson JX (2002) Ascorbate inhibits iNOS expression in endotoxin- and IFN gamma-stimulated rat skeletal muscle endothelial cells. FEBS Lett 520:122–126
-
(2002)
FEBS Lett
, vol.520
, pp. 122-126
-
-
Wu, F.1
Tyml, K.2
Wilson, J.X.3
-
97
-
-
0038311988
-
Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice
-
Wu F, Wilson JX, Tyml K (2003) Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice. Am J Physiol Regul Integr Comp Physiol 285:R50–R56
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.285
, pp. R50-R56
-
-
Wu, F.1
Wilson, J.X.2
Tyml, K.3
-
98
-
-
4644290734
-
Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression
-
Wu F, Wilson JX, Tyml K (2004) Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression. Free Radic Biol Med 37:1282–1289
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1282-1289
-
-
Wu, F.1
Wilson, J.X.2
Tyml, K.3
-
99
-
-
46349098098
-
Ascorbate inhibits iNOS induction in microvascular endothelial cells through inhibiting NADPH oxidase activity
-
Wu F, Tyml K, Wilson JX (2005) Ascorbate inhibits iNOS induction in microvascular endothelial cells through inhibiting NADPH oxidase activity. FASEB J 19:A507
-
(2005)
FASEB J
, vol.19
-
-
Wu, F.1
Tyml, K.2
Wilson, J.X.3
-
100
-
-
33751505566
-
Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells
-
Wu F, Schuster DP, Tyml K, Wilson JX (2007) Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells. Free Radic Biol Med 42:124–131
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 124-131
-
-
Wu, F.1
Schuster, D.P.2
Tyml, K.3
Wilson, J.X.4
-
101
-
-
31344468264
-
Propofol improves endothelial dysfunction and attenuates vascular superoxide production in septic rats
-
Yu HP, Lui PW, Hwang TL, Yen CH, Lau YT (2006) Propofol improves endothelial dysfunction and attenuates vascular superoxide production in septic rats. Crit Care Med 34:453–460
-
(2006)
Crit Care Med
, vol.34
, pp. 453-460
-
-
Yu, H.P.1
Lui, P.W.2
Hwang, T.L.3
Yen, C.H.4
Lau, Y.T.5
|