Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: Modulatory effect of nitric oxide

Journal of Leukocyte Biology

Volumn 75, Issue 6, 2004, Pages 1070-1078

  Sharma, Prashant ^a   Raghavan, Santhanam A V ^a   Saini, Rashmi ^a   Dikshit, Madhu ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Apoptosis; Ascorbic acid; Peroxynitrite; Phagocytosis

Indexed keywords

ARACHIDONIC ACID; ASCORBIC ACID; DEHYDROASCORBIC ACID; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL ADHESION; CELL AGGREGATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOTOXICITY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; ARACHIDONIC ACID; ASCORBIC ACID; CELLS, CULTURED; DEHYDROASCORBIC ACID; ESCHERICHIA COLI; FREE RADICAL SCAVENGERS; HUMANS; MACACA MULATTA; MALE; NADPH OXIDASE; NEUTROPHILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; OXYGEN; PEROXYNITROUS ACID; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

ANIMALIA; ESCHERICHIA COLI; LETHRINIDAE;

EID: 2642568618     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0903415     Document Type: Article

References (54)

1. Sethi, S., Dikshit, M. (2000) Modulation of polymorphonuclear leukocytes function by nitric oxide. Thromb. Res. 100, 223-247.
2. Babior, B. M. (2000) Phagocytes and oxidative stress. Am. J. Med. 109, 33-44.
3. Pieper, G. M., Clarke, G. A., Gross, S. J. (1994) Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes. J. Pharmacol. Exp. Ther. 260, 451-456.
4. Sethi, S., Singh, M. P., Dikshit, M. (1999) Nitric oxide-mediated augmentation of polymorphonuclear free radical generation after hypoxia-reoxygenation. Blood 93, 333-340.
5. Clancy, R. M., Leszczynska-Piziak, J., Abramson, S. B. (1992) Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J. Clin. Invest. 90, 1116-1121.
6. Seth, P., Kumari, R., Dikshit, M., Srimal, R. C. (1994) Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine. Blood 84, 2741-2748.
7. Sethi, S., Sharma, P., Dikshit, M. (2001) Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte. Nitric Oxide 5, 482-493.
8. Ischiropoulos, H., Zhu, L., Beckman, J. S. (1992) Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298, 446-451.
9. Malawista, S. E., Montgomery, R. R., Van Blaricom, G. (1996) Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible inhibitors of nitric oxide synthase. J. Leukoc. Biol. 60, 753-757.
10. Washko, P., Wang, Y., Levine, M. (1993) Ascorbic acid recycling in human neutrophils. J. Biol. Chem. 268, 15531-15535.
11. Wang, Y., Russo, T. A., Kwon, O., Chanock, S., Rumsey, S. C., Levine, M. (1997) Ascorbate recycling in human neutrophils: induction by bacteria. Proc. Natl. Acad. Sci. USA 94, 13816-13819.
12. Sharma, P., Raghavan, S. A. V., Dikshit, M. (2003) Role of ascorbic acid in the regulation of nitric oxide generation from polymorphonuclear leukocytes. Biochem. Biophys. Res. Commun, 308, 12-17.
13. Raghavan, S. A. V., Sharma, P., Dikshit, M. (2003) Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes. Thromb. Res. 110, 117-126.
14. Bredius, R. G. M., de Vries, E. E., Troelslral, A., Alphen, L. V., Weening, R. S., Van De Winkle, J. G., Out, T. A. (1993) Phagocytosis of staphylococcus aureus and hemophilus influenzae type B opsonized by polyclonal human IgG1 and IgG2 antibodies. J. Immunol. 151, 1463-1472.
15. Vermes, I., Hannen, C., Steffens-Nakken, H., Reutelingsperger, C. (1995) A novel assay for apoptosis, flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled Annexin V. J. Immunol. Methods 184, 39-51.
16. Jones, M. N. (1984) Nitrate reduction by shaking with cadmium: alternative to cadmium columns. Water Res. 18, 643-646.
17. Eiserich, J. P., Hristova, M., Cross, C. E., Jones, A. D., Freeman, B. A., Halliwell, B., van der Vliet, A. (1998) Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391, 393-397.
18. Williams, M. S., Noguchi, S., Ilenkart, P. A., Osawa, Y. (1998) Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death. J. Immunol. 161, 6526-6531.
19. Dikshit, M., Sharma, P. (2002) Nitric oxide-mediated modulation of free radical generation response in the rat polymorphonuclear leukocytes: a flowcytometric study. Methods Cell Sci. 24, 69-76.
20. Evans, R. M., Currie, L., Campbell, A. (1982) The distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration. Br. J. Nutr. 47, 473-482.
21. Washko, P., Rotrosen, D., Levine, M. (1990) Ascorbic acid accumulation in plated human neutrophils. FEBS Lett. 260, 101-104.
22. Carr, A., Frei, B. (2000) The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide. Free Radic. Biol. Med. 28, 1806-1814.
23. Mizutani, A., Tsukagoshi, N. (1999) Molecular role of ascorbate in enhancement of NO production in activated macrophage-like cell line J774.1. J. Nutr. Sci. Vitaminol. (Tokyo) 45, 423-435.
24. Heller, R., Unbehaun, A., Schellenberg, B., Mayer, B., Werner-Felmayer, G., Werner, E. R. (2001) L-Ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J. Biol. Chem. 276, 40-47.
25. Heller, R., Munscher-Paulig, F., Grabner, R., Till, U. (1999) L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells. J. Biol. Chem. 274, 8254-8260.
26. De Laurenzi, V., Melino, G., Savini, I., Annicchiarico-Petruzzelli, M., Finazzi-Agro, A., Avigliano, L. (1995) Cell death by oxidative stress and ascorbic acid regeneration in human neuroectodermal cell lines. Eur. J. Cancer 31A, 463-466.
27. Sakagami, B., Kuribayashi, N., lida, M., Hagiwara, T., Takahashi, H., Yoshida, H., Shiota, F., Ohata, H., Momose, K., Takeda, M. (1996) The requirement for and mobilization of calcium during induction by sodium ascorbate and by hydrogen peroxide of cell death. Life Sci. 58, 1131-1138.
28. Song, J. H., Shin, S. H., Wang, W., Ross, G. M. (2001) Involvement of oxidative stress in ascorbate-induced proapoptotic death of PC12 cells. Exp. Neurol. 169, 425-437.
29. Song, J. H. (2001) Oxidative stress induced by ascorbate causes neuronal damage in an in vitro system. Brain Res. 895, 66-72.
30. Krause, R., Patruta, S., Daxbock, F., Fladerer, P., Biegelmayer, C., Wenisch, C. (2001) Effect of vitamin C on neutrophil function after high-intensity exercise. Eur. J. Clin. Invest. 31, 258-263.
31. Levy, R., Shriker, O., Porath, A., Riesenberg, K., Schlaeffer, F. (1996) Vitamin C for the treatment of recurrent furunculosis in patients with impaired neutrophil functions. J. Infect. Dis. 173, 1502-1505.
32. Peters, E. M., Goetzsche, G. M., Grobelaar, B., Nokas, T. D. (1993) Vitamin C supplementation reduces the incidence of post-race symptoms of upper-respiratory tract infection in ultramarathon runners. Am. J. Clin. Nutr. 57, 170-174.
33. De la Fuente, M., Ferrandez, M. D., Burgos, M. S., Soler, A., Prieto, A., Miquel, J. (1998) Immune function in aged women is improved by ingestion of vitamins C and E. Can. J. Physiol. Pharmacol. 76, 373-380.
34. Shilotri, P. G. (1977) Phagocytosis and leukocyte enzymes in ascorbic acid-deficient guinea pigs. J. Nutr. 107, 1513-1516.
35. Andreasen, C. B., Frank, D. E. (1999) The effects of ascorbic acid on in vivo heterophil function. Avian Dis. 43, 656-663.
36. Volchegorskii, I. A., Vasil'kov, A. Y. (2000) Effects of ascorbic acid on lipid peroxidation and functional states of neutrophils at the early period after transurethral resection of the prostate. Bull. Exp. Biol. Med. 130, 1055-1057.
37. Victor, V. V., Guayerbas, N., Puerto, M., Medina, S., De la Fuente, M. (2000) Ascorbic acid modulates in vitro the function of macrophages from mice with endotoxic shock. Immunopharmacology 46, 89-101.
38. Sharma, S., Barthwal, M. K., Dikshit, M. (2002) NO synthesis and its regulation in the arachidonic acid-stimulated rat polymorphonuclear leukocytes. Nitric Oxide 7, 119-126.
39. Curnutte, J. T., Badwey, J. A., Robinson, J. M., Karnovsky, M. L. (1984) Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate. J. Biol. Chem. 259, 11851-11857.
40. Rao, K. M., Padmanabhan, J., Kilby, D. L., Cohen, H. J., Currie, M. S., Weinberg, J. B. (1992) Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor. J. Leukoc. Biol. 51, 496-500.
41. Vowells, S. J., Sekhsaria, S., Malech, H. L., Shelit, M., Fleisher, T. A. (1995) Flow cytometric analysis of the granulocyte respiratory burst: a comparative study of fluorescent probes. J. Immunol. Methods 178, 89-97.
42. Welch, R. W., Wang, Y., Crossman, A., Park, J. B., Kirk, K. L., Levine, M. (1995) Accumulation of vitamin C (ascorbate) and its oxidised metabolite dehydroascorbic acid occurs by separate mechanisms. J. Biol. Chem. 270, 12584-12592.
43. O'Donnell, V. B., Smith, G. C., Jones, O. T. G. (1994) Involvement of phenyl radicals in iodonium inhibition of flavoenzyme. Mol. Pharmacol. 46, 178-785.
44. Morikawa, M., Inoue, M., Tokumaru, S., Kogo, H. (1995) Enhancing and inhibitory effects of nitric oxide on superoxide anion generation in human polymorphonuclear leukocytes. Br. J. Pharmacol. 115, 1302-1306.
45. Radi, R., Beckman, J. S., Bush, K. M., Freeman, B. A. (1991a) Peroxynitrite-induced oxidation of sulfhydryls: the cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266, 4244-4250.
46. Cassina, A., Radi, R. (1996) Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport. Arch. Biochem. Biophys. 328, 309-316.
47. Radi, R., Beckman, J. S., Bush, K. M., Freeman, B. A. (1991b) Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288, 481-487.
48. Ward, C., Wong, T. H., Murray, J., Rahman, I., Haslett, C., Chilvers, E. R., Rossi, A. G. (2000) Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic GMP-independent mechanism. Biochem. Pharmacol. 59, 305-314.
49. Squadrito, G. L., Jin, X., Pryer, W. A. (1995) Stopped flow kinetic study of the reaction of ascorbic acid with peroxynitrite. Arch. Biochem. Biophys. 322, 53-59.
50. Guidarelli, A., De Sanctis, R., Cellini, B., Fiorani, M., Dacha, M., Cantoni, O. (2001) Intracellular ascorbic acid enhances the DNA single-strand breakage and toxicity induced by peroxynitrite in U937 cells. Biochem. J. 356, 509-513.
51. Roginsky, V. A., Stegmann, H. B. (1994) Ascorbyl radical as natural indicator of oxidative stress: qualitative regularities. Free Radic. Biol. Med. 17, 93-103.
52. Podomore, I. D., Griffiths, H. R., Herbert, K. E., Mistry, N., Mistry, P., Lunec, J. (1998) Vitamin C exhibits pro-oxidant properties. Nature 392, 559.
53. Childs, A., Jacobs, C., Kaminski, T., Halliwell, B., Leeuwenburgh, C. (2001) Supplementation with vitamin C and N-acetycysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic. Biol. Med. 31, 745-753.
54. Bode, A. M., Yavarow, C. R., Fry, D. A., Vargas, T. (1993) Enzymatic basis for the altered ascorbic acid and dehydroascorbic acid levels in diabetes. Biochem. Biophys. Res. Commun. 191, 1347-1353.