Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells

Free Radical Biology and Medicine

Volumn 42, Issue 1, 2007, Pages 124-131

  Wu, Feng ^a   Schuster, David P ^a   Tyml, Karel ^b   Wilson, John X ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Ascorbate; Endothelial cells; Interferon ; Lipopolysaccharide; NADPH oxidase; p47phox; Sepsis

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; CATALASE; GAMMA INTERFERON; HYDROGEN PEROXIDE; INTERFERON REGULATORY FACTOR 1; ISOPROTEIN; JANUS KINASE 2; MACROGOL; PROTEIN INHIBITOR; PROTEIN P47 PHOX; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STAT1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; INCUBATION TIME; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SEPSIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI; EXTREMITIES; HYDROGEN PEROXIDE; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; JANUS KINASE 2; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MICROCIRCULATION; MUSCLE, SKELETAL; NADPH OXIDASE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; STAT1 TRANSCRIPTION FACTOR;

ESCHERICHIA COLI;

EID: 33751505566     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.10.033     Document Type: Article

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