Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species

Free Radical Biology and Medicine

Volumn 36, Issue 10, 2004, Pages 1279-1288

  Goyal, Parag ^a   Weissmann, Norbert ^a   Grimminger, Friedrich ^a   Hegel, Cornelia ^a   Bader, Lucius ^a   Rose, Frank ^a   Fink, Ludger ^a   Ghofrani, Hossein A ^a   Schermuly, Ralph T ^a   Schmidt, Harald H H W ^b   Seeger, Werner ^a   Hänze, Jörg ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

Author keywords

Catalase; Free radicals; Hypoxia inducible factor 1; NAD(P)H oxidase 1; Oxygen sensing; Reactive oxygen species

Indexed keywords

CATALASE; DIPHENYLIODONIUM SALT; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; EXPRESSION VECTOR; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; LUNG SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; UPREGULATION;

CATALASE; CELL HYPOXIA; ENZYME INHIBITORS; EPITHELIAL CELLS; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUCIFERASES; LUNG; MEMBRANE PROTEINS; NADH, NADPH OXIDOREDUCTASES; NITRIC OXIDE SYNTHASE; ONIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

VECTORS;

EID: 11144356447     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.02.071     Document Type: Article

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